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  • 文章类型: Journal Article
    人们对概念化和诊断脆弱越来越感兴趣。少被理解,然而,关于老年人对“虚弱”一词的看法,以及被归类为“脆弱”的含义。这次范围审查的目的是绘制主要研究的广度;并描述其含义,感知,以及社区居住的老年人中脆弱语言的感知含义。8项研究被纳入审查,并确定了三个核心主题:(1)将脆弱理解为多个领域不可避免的与年龄相关的下降,(2)将脆弱感知为泛化标签,(3)感知语言对健康和医疗保健利用的影响。针对与身体虚弱的个人一起工作的医疗保健专业人员的临床实践建议包括:(1)保持对身体虚弱的整体看法,超越身体功能,包括社会心理和环境构造,(2)使用人称第一语言,(3)使用基于优势的方法讨论脆弱的方面。
    There is growing interest in conceptualizing and diagnosing frailty. Less is understood, however, about older adults\' perceptions of the term \"frail\", and the implications of being classified as \"frail\". The purpose of this scoping review was to map the breadth of primary studies; and describe the meaning, perceptions, and perceived implications of frailty language amongst community-dwelling older adults. Eight studies were included in the review and three core themes were identified: (1) understanding frailty as inevitable age-related decline in multiple domains, (2) perceiving frailty as a generalizing label, and (3) perceiving impacts of language on health and health care utilization. Clinical practice recommendations for health care professionals working with individuals with frailty include: (1) maintaining a holistic view of frailty that extends beyond physical function to include psychosocial and environmental constructs, (2) using person-first language, and (3) using a strengths-based approach to discuss aspects of frailty.
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  • 文章类型: Case Reports
    Clear cells sarcomas (CCS) are exceptionally rare in the tongue, with, to our knowledge, only three previous reports in anglo-saxon literature. Through our case, we will discuss the differential diagnosis of clear cells tumors of the tongue and bring this tumour closer to the newly described entity of the gastrointestinal tract named \"clear cells sarcoma-like gastrointestinal (SCCLGI)\", recently renamed \"gastrointestinal neuroectodermal tumour (GNET)\". SCCLGI/GNET share morphological and molecular characteristics with SCC but had until then been observed only in the digestive tract. Our case could be a lingual localization of a SCCLGI/GNET. SCC and SCCLGI/GNET characteristic molecular profil involves EWSR1-ATF1 [t(12; 22) (q13; q12)] and EWSR1-CREB1 [t(2; 22) (q34; q12)] fusion genes, but it is not specific of these tumours.
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  • 文章类型: Journal Article
    背景:关于儿童银屑病舌部受累的患病率和临床方面的信息很少。目的是评估患病率,银屑病患儿舌部受累的临床特点和危险因素。
    方法:本研究分两个阶段进行。我们表演了一个多中心,23个法国皮肤病学中心的横断面研究。在为期一年的研究中,所有患有牛皮癣的儿童均被系统地纳入。记录舌和银屑病的临床特征。评估了与银屑病和合并症的临床方面的关联。然后,我们进行了文献综述,以评估银屑病儿童中舌头受累的患病率及其对银屑病的阳性预测价值。在PUBMED数据库中使用以下关键字进行搜索:\“儿童\”和\“牛皮癣\”和(\“舌头\”或\“舌炎\”或\“迁徙性舌炎\”或\“良性迁徙性舌炎\”或\“地理舌头\”或\“裂开的舌头”)。
    结果:313例银屑病患儿中,有7.7%有舌头受累。临床方面为地理舌(4.2%),裂舌(2.8%)和两者(0.64%)。舌头受累与儿童的临床特征之间没有关联。引用了二百九十五篇文章,分析了三篇。牛皮癣在舌头异常的情况下非常罕见。
    结论:银屑病患儿舌部受累的患病率为7.7%。未显示临床或流行病学关联。舌头受累不会改变牛皮癣的治疗。在文献综述中,不可能评估银屑病中舌受累的患病率或其阳性预测值。
    BACKGROUND: Little information is available on the prevalence and clinical aspects of tongue involvement in children with psoriasis. The aim was to evaluate the prevalence, clinical aspects and risk factors concerning tongue involvement in children with psoriasis.
    METHODS: This study was carried out in two stages. We performed a multicentre, cross-sectional study in 23 French dermatology centers. All children seen for psoriasis during the one-year study were systematically included. The clinical features of the tongue and of psoriasis were recorded. Association with clinical aspects of psoriasis and comorbidities was evaluated. We then carried out a literature review to evaluate the prevalence of tongue involvement in children with psoriasis and its positive predictive value for psoriasis. A search was conducted in the PUBMED database using the following keywords: \"child\" and \"psoriasis\" and (\"tongue\" or \"glossitis\" or \"migratory glossitis\" or \"benign migratory glossitis\" or \"geographic tongue\" or \"fissured tongue\").
    RESULTS: 7.7% of the 313 children with psoriasis had tongue involvement. The clinical aspects were geographic tongue (4.2%), fissured tongue (2.8%) and both (0.64%). There was no association between tongue involvement and the clinical characteristics of the children. Two hundred and ninety-five articles were referenced and 3 were analysed. Psoriasis is very rare in cases of tongue abnormalities.
    CONCLUSIONS: The prevalence of tongue involvement was 7.7% in children with psoriasis. No clinical or epidemiological association was shown. Tongue involvement does not modify the management of psoriasis. In the literature review it was not possible to evaluate either the prevalence of tongue involvement in psoriasis or the positive predictive value thereof.
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