背景:童年,青春期,和年轻的成年(CAYA)癌症幸存者,有后期影响的风险,包括癌症相关的疲劳,心血管问题,和心理社会挑战,可能会受益于刺激行为调整的干预措施。三个护士主导的电子健康干预措施(REVIVER)通过视频通话和阐述以人为本的护理,开发了认知行为疗法和/或动机性访谈。这些干预措施的目标是:1)疲劳管理,2)更健康的生活方式行为,3)自我效能感和自我管理。本研究旨在评估REVIVER干预对CAYA癌症幸存者和医疗保健专业人员的可行性和潜在有效性。
方法:在单组混合方法设计中,16-54岁的CAYA癌症幸存者,治疗后五年以上,已注册。可行性,通过鲍恩的可行性研究结果进行评估,包括可接受性,实用性,整合和实施,需求和坚持。来自半结构化访谈的定性数据以及对幸存者和医疗保健专业人员的焦点小组访谈补充了评估。配对样本t检验评估自我报告生活质量的变化,疲劳,生活方式,自我管理,和基线自我效能感(T0),干预后(T1),6个月随访(T2)。
结果:干预措施和视频咨询通常是可以接受的,实用,并成功整合和实施。成功因素包括护士顾问(即,通信,方法,和态度)和个性化方法。障碍包括可持续性问题,技术问题,干预持续时间短。关于需求,71.4%,65.4%,和100%的合格CAYA癌症幸存者从事疲劳(N=15),生活方式(N=17)和赋权(N=3)干预,分别,采访了5、5和2名参与者,相应地。注意到对赋权干预的兴趣(需求)低(N=3),疲劳和赋权干预的辍学率为三分之一(依从性)。生活质量的提高,疲劳(疲劳干预),生活方式(生活方式干预),自我效能感,在完成疲劳和生活方式干预的幸存者中,自我管理是显而易见的,在干预后立即和干预后六个月观察到中等和较大的效应大小。
结论:我们的研究证明了护士主导的视频指导(REVIVER干预)的可行性,尽管对授权干预的需求较低,对疲劳和授权干预的依从性较低。对于完成干预措施的人发现的中高效应大小对于研究REVIVER干预措施的有效性的未来研究具有潜在的临床意义。
BACKGROUND: Childhood, adolescent, and young adult (CAYA) cancer survivors, at risk for late effects, including cancer-related fatigue, cardiovascular issues, and psychosocial challenges, may benefit from interventions stimulating behaviour adjustments. Three nurse-led eHealth
interventions (REVIVER) delivered via video calls and elaborating on person-centred care, cognitive behaviour therapy and/or motivational interviewing were developed. These
interventions target: 1) fatigue management, 2) healthier lifestyle behaviours, and 3) self-efficacy and self-management. This
study aimed to assess the feasibility and potential effectiveness of the REVIVER
interventions for CAYA cancer survivors and healthcare professionals.
METHODS: In a single-group mixed methods design, CAYA cancer survivors aged 16-54, more than five years post-treatment, were enrolled. Feasibility, assessed via Bowen\'s outcomes for feasibility studies, included acceptability, practicality, integration and implementation, demand and adherence. Qualitative data from semi-structured interviews and a focus group interview with survivors and healthcare professionals supplemented the evaluation. Paired sample t-tests assessed changes in self-reported quality of life, fatigue, lifestyle, self-management, and self-efficacy at baseline (T0), post-intervention (T1), and 6-month follow-up (T2).
RESULTS: The interventions and video consults were generally acceptable, practical, and successfully integrated and implemented. Success factors included the nurse consultant (i.e., communication, approach, and attitude) and the personalised approach. Barriers included sustainability concerns, technical issues, and short intervention duration. Regarding demand, 71.4%, 65.4%, and 100% of eligible CAYA cancer survivors engaged in the fatigue (N = 15), lifestyle (N = 17) and empowerment (N = 3) intervention, respectively, with 5, 5 and 2 participants interviewed, correspondingly. Low interest (demand) in the empowerment intervention (N = 3) and dropout rates of one-third for both fatigue and empowerment interventions were noted (adherence). Improvements in quality of life, fatigue (fatigue intervention), lifestyle (lifestyle intervention), self-efficacy, and self-management were evident among survivors who completed the fatigue and lifestyle interventions, with medium and large effect sizes observed immediately after the intervention and six months post-intervention.
CONCLUSIONS: Our
study demonstrates the feasibility of nurse-led video coaching (REVIVER
interventions) despite lower demand for the empowerment intervention and lower adherence to the fatigue and empowerment interventions. The medium and high effect sizes found for those who completed the interventions hold potential clinical significance for future studies investigating the effectiveness of the REVIVER
interventions.