新的数据表明,1型糖尿病在儿童中是一种比成人更具侵袭性的疾病,在病理生理学和临床过程中具有重要差异。因此,在这两个人群中,疾病改善疗法的疗效可能不同.了解儿童1型糖尿病改善疗法的发展和调节途径将使工业,学术界,资助者,倡导团体,和监管机构将新科学转化为临床护理。这份共识报告描述了儿童和成人之间1型糖尿病的基本差异,并提出了一种深思熟虑的方法来更好地了解1型糖尿病治疗的发展和调节途径。
Emerging data suggest that type 1 diabetes is a more aggressive disease in children than in adults, with important differences in pathophysiology and clinical course. Therefore, the efficacy of disease-modifying therapies may be different in the two populations. Understanding the developmental and regulatory pathways for type 1 diabetes-modifying therapies in children will enable industry, academia, funders, advocacy groups, and regulators to translate new science to clinical care. This
consensus report characterizes the fundamental differences in type 1 diabetes between children and adults and proposes a thoughtful approach to better understand the development and regulatory pathways for type 1 diabetes therapies.