在COVID-19大流行之前有慢性阻塞性肺疾病(HCOPD)病史的人中,关于季节性流感疫苗接种(SIV)的文献有限,没有关于评估大流行后年份的主题的信息。这项横断面研究使用了2017年至2022年的行为危险因素监测调查(BRFSS)数据(n=822,783名50-79岁的成年人;50.64%的男性)。暴露是HCOPD,结果是过去一年的SIV。加权和调整后的逻辑回归模型进行了总体和显著的效应修饰:吸烟状况,性别,和年份。与没有总体HCOPD和吸烟状况相比,患有HCOPD显着增加了SIV的加权调整赔率(WAO)。性别,和年份。从2017年到2022年,目前,前者,从不吸烟者患有HCOPD,SIV的WAO为:1.36(1.28,1.45),1.35(1.27,1.43),和1.18(1.09,1.27),分别。在目前患有HCOPD的男性中,前者,从不吸烟,SIV的WAO为:1.35(1.23,1.48),1.45(1.33,1.58),和1.23(1.05,1.44),分别。在患有HCOPD的女性中,前者,从不吸烟,SIV的WAO为:1.31(1.20,1.43),1.24(1.15,1.35),和1.13(1.04,1.23),分别。研究结果表明,在COVID-19大流行期间和之后,在2020年和2022年,男性接受SIV的WAO比率明显高于女性。更具体地说,在2020年和2022年,曾吸烟者患有HCOPD的男性接受SIV的WAOR显著高于女性.了解吸烟状况和性别对SIV接收的潜在障碍,尤其是在大流行期间,尤其是对于受HCOPD影响的个体,对于在大流行等国家危机时期更好的卫生干预措施至关重要。此外,在患有HCOPD的人群中,SIV收据较低,应该努力加以改进。
There is limited literature regarding seasonal influenza vaccination (SIV) among those with a history of chronic obstructive pulmonary disease (HCOPD) prior to the COVID-19 pandemic, and no information on the topic assessing the years following the pandemic. This cross-sectional
study used the Behavioral Risk Factor Surveillance Survey (BRFSS) data from the years 2017 to 2022 (n = 822,783 adults ages 50-79 years; 50.64% males). The exposure was a HCOPD, and the outcome was SIV within the past year. Weighted and adjusted logistic regression models were conducted overall and by the significant effect modifiers: smoking status, sex, and year. Having an HCOPD significantly increases the weighted adjusted odds (WAO) of SIV when compared to not having an HCOPD overall and by smoking status, sex, and year. For 2017 through 2022, among all current, former, and never smokers with an HCOPD, the WAO of SIV were: 1.36 (1.28, 1.45), 1.35 (1.27, 1.43), and 1.18 (1.09, 1.27), respectively. Among males with an HCOPD who were current, former, and never smokers, the WAO of SIV were: 1.35 (1.23, 1.48), 1.45 (1.33, 1.58), and 1.23 (1.05, 1.44), respectively. Among females with an HCOPD who were current, former, and never smokers, the WAO of SIV were: 1.31 (1.20, 1.43), 1.24 (1.15, 1.35), and 1.13 (1.04, 1.23), respectively.
Study findings suggest males had significantly greater WAO ratios of receiving SIV than females in 2020 and 2022, during and after the COVID-19 pandemic. More specifically, males with an HCOPD who were former smokers had significantly greater WAOR of receiving SIV than females in 2020 and 2022. Understanding the potential barriers to SIV receipt by smoking status and sex, especially during a pandemic, and especially for individuals impacted by an HCOPD, is essential for better health interventions in times of a national crisis such as a pandemic. Additionally, SIV receipt is low among those with an HCOPD, and efforts should be made to improve this.