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  • 文章类型: Journal Article
    切口疝是机器人根治性前列腺切除术后的常见并发症。接受机器人前列腺切除术的男性的观察数据表明,横向闭合比垂直闭合导致更低的疝发生率。我们试图比较垂直和横向拔除部位闭合后机器人根治性前列腺切除术后切口疝的发生率。
    我们进行了临床整合,交叉,在一个三级转诊中心(2016年1月-2021年9月)进行的整群随机试验,比较了1356例接受微创根治性前列腺切除术的患者行横向和垂直摘除部位切除术后的疝发生率.主要结果是通过体格检查和自我报告的患者调查定义的前列腺切除术后15个月内切口疝的组间发生率。
    总的来说,197例(20%)患者在15个月内出现切口疝,797在此期间没有切口疝,362例患者的切口疝结局数据缺失.我们发现两种切口类型之间的疝发生率没有显着差异(绝对组间差异1.8%;95%CI-3.4%,6.6%;P=.5)在初步分析或3次敏感性分析中。值得注意的是,因为使用了疝气的包容性定义,这些数据不能用于估计切口疝的真实患病率.
    外科医生在提取标本时应选择他们最舒适的切口和闭合方法。对手术技术的修改研究最好以随机比较的方式进行,和临床整合,交叉,整群随机试验允许大型试验在单个中心以低成本完成.
    ClinicalTrials.gov:NCT01407263。
    UNASSIGNED: Incisional hernias are a frequent complication following robotic radical prostatectomy. Observational data in men undergoing robotic prostatectomy suggest that transverse closure resulted in lower hernia rates than vertical closure. We sought to compare the incidence of incisional hernia after robotic radical prostatectomy after vertical and transverse extraction site closure.
    UNASSIGNED: We conducted a clinically integrated, crossover, cluster randomized trial at a single tertiary referral center (January 2016-September 2021) comparing the rate of hernia after transverse vs vertical extraction site excision in 1356 patients treated with minimally invasive radical prostatectomy. The primary outcome was between-group incidence of incisional hernia within 15 months of prostatectomy defined by physical examination and self-reported patient surveys.
    UNASSIGNED: Overall, 197 (20%) patients developed an incisional hernia within 15 months, 797 did not have an incisional hernia within this period, and 362 had missing outcome data regarding incisional hernia. We found no significant difference in hernia rates between the 2 incision types (absolute between-group difference 1.8%; 95% CI -3.4%, 6.6%; P = .5) in the primary analysis or in the 3 sensitivity analyses. Notably, because of the inclusive definition of hernia used, these data cannot be used as an estimate of the true prevalence of incisional hernia.
    UNASSIGNED: Surgeons should choose the incision and closure approach they are most comfortable with when extracting specimens. Studies of modifications to the surgical technique are best conducted as randomized comparisons, and the clinically integrated, crossover, cluster randomized trial allows large trials to be completed at a single center and at low cost.
    UNASSIGNED: ClinicalTrials.gov: NCT01407263.
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  • 文章类型: Journal Article
    水平叮咬X光片在牙科中广泛且频繁地使用,并且在诊断近端龋齿和近端牙槽骨水平方面非常可靠。然而,它在检测邻间根龋方面是有挑战性的,水平和/或垂直牙槽骨丢失,和分叉牵连。本文的目的是评估与水平咬伤技术相比,垂直咬伤图像在龋齿和牙槽骨水平诊断中的准确性。
    这20名患者中的每一名都有八张咬痕X射线照片,以获得相同后部区域的四张水平咬痕(对照)和四张垂直咬痕(实验)图像;在传感器板上使用钢丝(3毫米)以帮助稍后测量放大率。X射线照片经过数字化处理,并由两名专家修复专家评估龋齿,并由两名经验丰富的牙周病医生评估骨质流失。他们还被比作“黄金标准”,“这是使用临床和影像学检查进行诊断。在图像评估期间,他们彼此失明。
    在20名患者的样本量中,70%是男性,30%是女性,平均年龄29.9岁.获得四个标准叮咬X射线照片的平均X射线照片数量对于垂直叮咬X射线照片为5.9±1.7,对于水平叮咬X射线照片为5.3±1.3。从牙釉质交界处(CEJ)到牙髓骨水平的测量结果未显示水平和垂直咬合X射线照片之间的显着差异。与水平咬合(57.5%)相比,垂直咬合(100%)中磨牙中分叉面积的检测要高得多(P<0.0001)。结论:在分叉受累的检测中,垂直咬痕X光片比水平咬痕X光片占上风,龋齿检测,和牙槽骨丢失。因此,强烈建议在龋齿和牙周病患者中使用垂直咬牙,而不是常规的水平咬牙。
    UNASSIGNED: Horizontal bitewing radiographs are widely and frequently used in dentistry and are very reliable in diagnosing proximal caries and interproximal alveolar bone level. However, it is challengeable in detecting interproximal root caries, horizontal and/or vertical alveolar bone loss, and furcation involvements. The aim of this article was to assess the accuracy of vertical bitewing images in the diagnosis of caries and alveolar bone level compared to the horizontal bitewing technique.
    UNASSIGNED: Each one of the 20 patients had eight bitewing radiographs to get four horizontal bitewing (control) and four vertical bitewing (experimental) images for the same posterior area; a steel wire (3 mm) was used on the sensor plate to help measure the magnification later on. The radiographs were processed digitally and were evaluated for caries by two expert restorative specialists and for bone loss by two experienced periodontists. They were also compared to the \"gold standard,\" which is using of both clinical and radiographic examination for diagnosis. They were blinded to each other during images evaluation.
    UNASSIGNED: Of the 20-patient sample size, 70% were male and 30% were female, with a mean age of 29.9. The average number of radiographs taken to achieve four standard bitewing radiographs was 5.9 ± 1.7 for vertical bitewings and 5.3 ± 1.3 for horizontal bitewing radiograph. The measurements from the cementoenamel junction (CEJ) to the level of crestal bone didn\'t show a significant difference between the horizontal and vertical bitewing radiographs. The detection of furcation area in the molar teeth was much higher in the vertical bitewing (100%) compared to the horizontal bitewing (57.5%) (P < 0.0001). Conclusion: The vertical bitewing radiograph has the upper hand over the horizontal bitewing radiograph in the detection of furcation involvement, caries detection, and alveolar bone loss. Therefore, it is highly recommended to use vertical bitewing in caries and patients with periodontal disease rather than the conventional horizontal bitewing.
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  • 文章类型: Journal Article
    OBJECTIVE: Anterior rectocele is usually an asymptomatic condition in many women, yet it can be associated with obstructed defaecation syndrome (ODS). Transperineal repair of rectocele (TPR) has been followed by variable rates of improvement in ODS. The present pilot randomized clinical trial aimed to evaluate the outcome of TPR with vertical plication (VP) of the rectovaginal septum compared to horizontal plication (HP).
    METHODS: Adult women with anterior rectocele were recruited to the study and were randomly allocated to one of two equal groups. The first group underwent TPR with VP of the rectovaginal septum and the second group underwent TPR with HP. The main outcome measures were improvement in ODS, recurrence of rectocele, complications and dyspareunia.
    RESULTS: The trial included 40 female patients with anterior rectocele. There was no significant difference between the two groups regarding the postoperative Wexner score. Complete cure and significant improvement in ODS symptoms were comparable after the two techniques. The reduction in rectocele size after HP was significantly greater than after VP (1.7 vs. 2.6, P < 0.0001). Significant improvement in dyspareunia was recorded after HP (P = 0.001) but not after VP (P = 0.1). There was no significant difference between the two groups with regard to operating time, complications and recurrence.
    CONCLUSIONS: VP and HP of the rectovaginal septum in TPR were associated with a comparable improvement in ODS symptoms and similar complication rates. HP was followed by a greater reduction in the rectocele size and greater improvement in dyspareunia than VP.
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  • 文章类型: Journal Article
    BACKGROUND: A high level of workplace social capital (WSC) may contribute to the protection of employees\' health. We hypothesized that a participatory workplace intervention would increase the level of WSC defined as vertical WSC (i.e. WSC linking together employees and their leaders) and horizontal WSC (i.e. WSC bonding employees together).
    METHODS: We conducted a secondary data analysis of a cluster randomized controlled trial that was implemented among all employees in 78 municipal Danish pre-schools (44 intervention and 34 control group schools). The study sample consisted of 606 employees, 386 in the intervention and 220 in the control group. The intervention aimed to improve the psychosocial working environment by using a participatory approach and focusing on core job tasks. Vertical and horizontal WSC was measured by five and four items, respectively, at baseline and at 24-months follow-up. We estimated intervention effect by calculating the interaction of change over time by group assignment (intervention versus control group) and included workplace identification number in a repeated statement to take into account that employees were nested within workplaces. We conducted post-hoc analyses to examine whether intervention effect differed by implementation degree.
    RESULTS: WSC decreased in both groups. In the main analyses, there was no statistically significant difference between intervention and control group, neither for vertical nor horizontal WSC. However, when we excluded intervention workplaces with a low degree of implementation, we found a statistically significant difference between the intervention and the control group (estimate: 0.25, 95% CI: 0.00 to 0.50, p = 0.049), indicating that vertical WSC decreased in the control group and remained stable in the intervention group.
    CONCLUSIONS: There was not a statistically significant difference between intervention and control group in the main analysis. Post-hoc analyses, however, suggest that the intervention may have prevented a decrease in vertical WSC among employees in workplaces with a high or a medium degree of implementation. A conference abstract with the key results of this study has been previously presented and published, European Journal of Public Health, Volume 28, Issue suppl_4, November 2018, cky260, https://academic.oup.com/eurpub/article/28/suppl_4/cky260/5187184 .
    BACKGROUND: ISRCTN16271504 , retrospectively registered on November 15, 2016.
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  • 文章类型: Journal Article
    BACKGROUND: It is important to restore horizontal and vertical stability to the acromioclavicular (AC) joint when treating dislocations of this joint. Most surgical stabilization techniques of the AC joint have primarily addressed the coracoclavicular ligament complex; however, these techniques may not satisfactorily restore horizontal stability to the AC joint.
    OBJECTIVE: To evaluate the strength and bidirectional stability of 3 AC joint stabilizing techniques in a cadaveric model.
    METHODS: Controlled laboratory study.
    METHODS: A total of 24 cadaveric shoulders were randomly allocated to 3 treatment groups. For each group, a standardized AC joint stabilizing procedure was performed, and the specimens were potted for mechanical testing. The following reconstruction techniques were used: a single clavicular tunnel for group A, a double clavicular tunnel for group B, and a double clavicular tunnel plus suture fixation across the AC joint for group C. The specimens underwent cyclic loading in the horizontal and vertical planes and then load to failure. Eight control specimens also underwent cyclic loading in both planes. Construct stiffness during cyclic loading, change in displacement after cyclic loading in both planes, load to failure in the vertical plane, and mode of failure were evaluated, and stiffness was compared among the treatment groups as well as with a control group.
    RESULTS: There was a decrease in joint stiffness for all groups, including controls, during the cyclic loading. Compared with controls, all 3 treatment groups demonstrated equivalent stiffness and displacement in the vertical plane. In the horizontal plane, all 3 treatment groups demonstrated decreased stiffness, increased displacement, or both when compared with controls. When groups were compared, no treatment arm proved superior regarding stiffness or displacement in either plane. Load-to-failure testing of the 3 treatment groups in the vertical plane demonstrated construct strength and stiffness comparable with reports for the native AC joint. The mode of failure was predominantly fracture at the point of fixation to the testing apparatus.
    CONCLUSIONS: There was no difference in bidirectional strength and stability between the single- and double-clavicular tunnel techniques of coracoclavicular reconstruction. The addition of a stabilizing suture across the AC joint does not improve horizontal stability in the absence of repair of the AC joint capsule and deltotrapezial fascia.
    CONCLUSIONS: This laboratory study provides further evidence of the importance of the AC joint capsule and associated soft tissues in affording horizontal stability to that joint. Information from this and subsequent studies utilizing a bidirectional model can influence the choice of surgical procedure in the clinical treatment of AC joint dislocations.
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  • 文章类型: Journal Article
    工作场所社会资本(WSC)可能有益于员工的健康和福祉;然而,大多数研究都从个人而不是工作场所层面分析了WSC。我们测试是否较高水平的垂直WSC(员工和上级之间的WSC)和水平WSC(员工之间的WSC),在工作场所层面衡量,前瞻性地与更高水平的员工幸福相关。
    使用干预研究的数据,我们分析了工作场所汇总的纵向和横向WSC在基线与工作满意度之间的关联,24个月随访时的疲惫和睡眠障碍。样本包括606名市政学前雇员(71个工作场所)。我们根据个人和工作场所的特点进行了调整,结果的基线评分,干预状况,以及暴露与干预状态的相互作用。我们在SAS中使用Genmod程序,并重复陈述以说明工作场所内个体的相关性。我们使用个体水平WSC测量重复分析。
    基线时纵向和横向WSC水平较高,预测工作满意度水平较高(分别为0.20,p=0.01和0.24,p=0.01),而在调整最大的模型中,随访时的疲惫水平较低(-0.33,p=0.04和-0.43,p=0.04)。对个体水平测量的分析产生了类似的结果,并进一步显示了较高水平的水平WSC与较低水平的睡眠障碍之间的关联。
    纵向和横向WSC水平的提高与市政学前教育员工的幸福感预期相关。因此,工作场所可以考虑将重点放在改善WSC上,作为确保或改善员工福祉的一种手段。
    Workplace social capital (WSC) may be beneficial for employees\' health and well-being; however, most studies have analyzed WSC on the individual and not the workplace level. We test whether higher compared to lower levels of vertical WSC (WSC between employees and superiors) and horizontal WSC (WSC between employees), measured at the workplace level, is prospectively associated with higher levels of employees\' well-being.
    Using data from an intervention study, we analyzed associations between workplace aggregated vertical and horizontal WSC at baseline with job satisfaction, exhaustion and sleep disturbances at 24-months follow-up. The sample included 606 municipal pre-school employees (71 workplaces). We adjusted for individual and workplace characteristics, baseline scores of outcomes, intervention status, and the interaction of exposure with intervention status. We used the Genmod procedure in SAS with a repeated statement to account for correlation of individuals within workplaces. We repeated analyses using individual-level WSC measurements.
    Higher levels of vertical and horizontal WSC at baseline predicted a higher level of job satisfaction (0.20, p = 0.01 and 0.24, p = 0.01, respectively) and a lower level of exhaustion (- 0.33, p = 0.04 and - 0.43, p = 0.04) at follow-up in the most adjusted model. Analyses with individual-level measures yielded similar results and further showed an association of a higher level of horizontal WSC with a lower level of sleep disturbances.
    Higher levels of vertical and horizontal WSC were prospectively associated with better well-being of employees in municipal pre-schools. Workplaces may thus consider focusing on improving WSC as a means for ensuring or improving employees\' well-being.
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  • 文章类型: Journal Article
    OBJECTIVE: To compare the effects of horizontal and vertical vaginal cuff closure techniques on vagina length after vaginal hysterectomy.
    METHODS: Prospective randomized study (Canadian Task Force classification I).
    METHODS: Teaching and research hospital, a tertiary center.
    METHODS: Fifty-two women with POP-Q stage 0 or 1 uterine prolapse were randomized into 2 groups using vertical (n = 26) or horizontal (n = 26) vaginal cuff closure.
    METHODS: All patients underwent vaginal hysterectomy.
    RESULTS: Vagina length in the 2 groups was compared preoperatively, immediately after surgery, and at 6 weeks postoperatively. Mean (SD) preoperative vagina length in the horizontal and vertical groups was similar (7.87 [0.92] cm vs 7.99 [0.78] cm; p = .41). Immediately postoperatively, the vagina was significantly shorter in the horizontal group than in the vertical group (6.61 [0.89] cm vs 7.51 [0.74] cm; p < .001). At 6 weeks postoperatively, the vagina was still significantly shorter in the horizontal group (6.55 [0.89] cm vs 7.42 (0.73) cm; p < .001). The mean difference in vagina length before and after surgery was also significantly higher in the horizontal group than in the vertical group (-1.26 [0.12] cm vs 0.49 [0.11] cm; p < .001).
    CONCLUSIONS: Vertical cuff closure during vaginal hysterectomy seems to preserve vagina length better than does horizontal cuff closure.
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