精神病在神经认知障碍患者中很常见,很难管理,并给患者和护理人员造成相当大的负担和压力。开发有效的治疗方法是一个巨大的未满足的医疗需求,但由于需要更新的共识诊断标准,研究已经放缓。为了满足这一需求,国际心理儿科学协会启动了一项制定临床使用标准的程序,研究,和治疗发展努力。该过程包括临床,监管,和行业利益相关者以及全球老年精神病学专家网络对两项调查的回应(N=336)。共识过程的结果证实,临床医生希望对Jeste和Finkel在2000年提出的定义的各个方面进行详细说明,以确保标准得到适当应用。根据讨论,调查,和新兴的研究,对标准进行了修订,以适用于所有主要和轻度神经认知障碍患者的精神病.其他重要的变化包括提供幻觉和妄想的例子,并澄清时间进程,影响,和排除标准。严重和轻度神经认知障碍中精神病的定义可用于推进许多类型的研究,包括开发急需的药物和非药物干预措施,以治疗神经认知障碍患者的精神病。
Psychosis is common among individuals with neurocognitive disorders, is difficult to manage, and causes considerable burden and stress to patients and caregivers. Developing effective treatments is a substantial unmet medical need but research has been slowed by the need for updated
consensus diagnostic criteria. To address this need, the International Psychogeriatrics Association initiated a process to develop criteria for clinical use, research, and treatment development efforts. The process included clinical, regulatory, and industry stakeholders as well as input from a global network of experts in geriatric psychiatry responding to two surveys (N = 336). Results from the
consensus process confirmed that clinicians wanted elaboration of aspects of the definition proposed by Jeste and Finkel in 2000 to ensure that the criteria are applied appropriately. Based on discussions, the survey, and emerging research, criteria were revised to apply to psychosis occurring with all major and mild neurocognitive disorders. Other important changes include providing examples of
hallucinations and delusions and clarifying time course, impact, and exclusionary criteria. This definition of psychosis in major and mild neurocognitive disorders can be used to advance many types of research including development of much needed pharmacologic and nonpharmacologic interventions for psychosis in patients with neurocognitive disorders.