以温度计为信号阅读器的光热试剂介导的便携式检测平台由于其简单性受到了广泛的关注,低成本,和实用性。然而,开发光热试剂,具有优异的光热转换效果,便于合成,优选不对生物传感应用进行任何修改,仍然具有挑战性。在这里,已开发出一种简单而快速的种子介导的原位合成策略,用于制备具有显着的光热转换效果的金纳米星(AuNSs)。通过简单地改变参与原位合成过程的种子大小和组分浓度,AuNS具有可调节的几何形状,允许光热转换被调整到一个高水平的最佳生物传感。同时,通过研究AuNS的形态与光热效应之间的关系,获得了对光热转化机理的准确理解。随后,使用抗坏血酸(AA)作为模型目标,初步论证了AuNSs在构建便携式光热检测平台中的应用。AuNSs的这种原位制备策略不仅表现出显著的光热转换效果,而且避免了复杂和耗时的合成和修饰。因此,通过简单地将目标浓度转换为AA的浓度,它具有扩展到其他目标的便携式检测的巨大潜力。
Photothermal reagent-mediated portable detection platforms using thermometers as signal readers have received extensive attention due to their simplicity, low cost, and practicality. However, exploitation photothermal reagent with excellent photothermal conversion effect, convenient to synthesize, preferably without any modification for biosensing application, is still challenging. Herein, a simple and rapid seed-mediated in situ synthesis strategy has been developed for the preparation of gold nanostars (AuNSs) with remarkable photothermal conversion effect. By simply changing the seed size and component concentrations involved in the in situ synthesis process, AuNSs have adjustable geometries, allowing the photothermal conversion to be tuned to a high level optimal for biosensing. Meanwhile, an accurate understanding of the photothermal conversion mechanism is obtained by studying the relationship between the morphology of AuNSs and the photothermal effect. Subsequently, using ascorbic acid (AA) as a model target, the preliminary application of AuNSs in constructing a portable photothermal detection platform has been demonstrated. This in situ preparation strategy of AuNSs not only exhibits remarkable photothermal conversion effect, but also avoids complicated and time-consuming synthesis and modification. Therefore, it has great potential to be extended to portable detection of other targets by simply converting the concentration of the target to that of AA.