■为了说明基因在卵巢早衰(POI)和该领域的合作中取得的成果,并探索关键主题和未来方向。
■1990年至2022年之间发表的与POI基因有关的文章和评论是从WebofScience核心收藏(WoSCC)中检索的,以进行总的文献计量分析。工具被分析发表,国家,机构,journal,作者,参考,关键词,主题类别,资助机构,并使用文献计量在线分析平台研究热点,书目共现矩阵生成器(BICOMB),CiteSpaceV,和VOSviewer。
■本研究共纳入2,232篇论文。文章在52个国家发表,美国出版最多的,其次是中国。共有308个机构为相关出版物做出了贡献。山东大学发表的论文最多。秦Y的团队发表了最相关的论文。人类生殖与生育力和不育是论文最多的两个期刊。X染色体异常,转录因子突变,FMR1基因是更多POI的方向,DNA修复是近年来研究前沿的重点。
■本研究首次总结了POI基因研究的相关文献,并分析了该领域的当前热点和未来趋势。这些发现可以进一步揭示病因,诊断,和POI的治疗,有利于研究者掌握POI女性的遗传动态。
UNASSIGNED: To illustrate the results achieved by genes in premature ovarian insufficiency (POI) and collaborations in the field, and to explore key themes and future directions.
UNASSIGNED: Articles and reviews related to POI genes published between 1990 and 2022 were retrieved from the Web of Science core collection (WoSCC) for the total bibliometric analysis. Tools were analyzed for publication, country, institution, journal, authors, reference, keywords, subject categories, funding agencies, and research hotspots using a bibliometric online analysis platform, Bibliographic Co-occurrence Matrix Builder (BICOMB), CiteSpace V, and VOSviewer.
UNASSIGNED: A total of 2,232 papers were included in this
study. Articles were published in 52 countries, with the United States publishing the most, followed by China. A total of 308 institutions contributed to relevant publications. Shandong University published the most papers. Qin Y\'s team published the most relevant papers. Human reproduction and fertility and sterility are the two journals with the most papers. X-chromosome abnormalities, transcription factor mutations, and FMR1 genes are the directions of more POI, and DNA repair is the keyword of the research frontier in recent years.
UNASSIGNED: This
study summarizes the relevant literature on POI gene research for the first time and analyzes the current hotspots and future trends in this field. The findings can further reveal the etiology, diagnosis, and treatment of POI, which is beneficial for researchers to grasp the genetic dynamics of POI women.