在人群中,憩室炎和痔疮直肠炎是重要的公共卫生问题。我们通过一项病例对照研究,包括410例病例和401例对照,研究了某些植物性食物的摄入与憩室炎或痔疮发作之间的潜在关联。我们使用了半定量食物频率问卷。根据24小时召回对摄入量进行了额外量化。植物性食品或衍生食品按其主要化学成分分为乙醇,咖啡因/可可碱/可可碱,辣椒素,Alliin,酸,丁香酚,和其他食物,如姜黄素。考虑中的植物性食物的总体摄入量的平均得分为6.3分,病例(8.5)明显高于对照组(4.1)。出现憩室炎或痔疮直肠炎的病例的总体摄入量相似。病例的总摄入量处于上四分位数的可能性为13倍(>7分),与对照组相比。解释性logistic回归模型显示,辣椒素化学食品组与憩室炎和痔疮直肠炎的相关性最强,其次是乙醇,丁香酚,咖啡因/可可碱/可可碱,和酸。艾琳和其他食物组均未显示任何关联。High,经常食用辣椒素,其次是乙醇,丁香酚,咖啡因/可可碱/可可碱,和酸增加憩室炎和痔疮直肠炎的风险。
Diverticulitis and hemorrhoidal proctitis in the population are significant public health problems. We studied the potential association between the intake of certain plant foods and diverticulitis or hemorrhoidal episodes through a
case-control study including 410 cases and 401 controls. We used a semiquantitative food frequency questionnaire. The intake was additionally quantified according to a 24 h recall. The plant foods or derived food products were categorized by their main chemical components into ethanol, caffeine/theine/theobromine, capsaicin, alliin, acids,
eugenol, and miscellaneous foods such as curcumin. The mean score for overall intake of plant foods under consideration was 6.3 points, and this was significantly higher in cases (8.5) than in controls (4.1). Overall intake was similar in cases presenting with diverticulitis or hemorrhoidal proctitis. Cases had 13 times the odds of being in the upper quartile for overall intake (>7 points), compared to controls. Explanatory logistic regression models showed that the strongest association with diverticulitis and hemorrhoidal proctitis was shown by the chemical food group of capsaicin, followed by ethanol,
eugenol, caffeine/theine/theobromine, and acids. Neither alliin nor miscellaneous food groups showed any association. High, frequent consumption of capsaicin, followed by ethanol,
eugenol, caffeine/theine/theobromine, and acids increase the risk of diverticulitis and hemorrhoidal proctitis.