esophageal mass

食管肿块
  • 文章类型: Journal Article
    一名54岁的妇女出现食管病变升高。计算机断层扫描(CT)和磁共振成像显示胰头肿块。内窥镜超声(EUS)显示明确的,圆形,低回声肿块,这被认为是淋巴结肿大。对食管和胰头上方的肿块进行了EUS引导的细针穿刺活检(FNAB)。经病理证实的上皮细胞和多核巨细胞T-SPOT阳性。临床上,怀疑有结核性淋巴结炎和食管结核,抗结核治疗的成功治疗产生了良好的反应。我们的发现表明EUS-FNAB可用于诊断食管结核。
    A 54-year-old woman presented with an elevated esophageal lesion. Computed tomography (CT) and magnetic resonance imaging revealed a mass in the pancreatic head. Endoscopic ultrasound (EUS) showed a well-defined, round, hypoechoic mass, which was considered lymph node enlargement. An EUS-guided fine-needle aspiration biopsy (FNAB) was performed on the esophagus and the mass above the pancreatic head. The pathologically confirmed epithelial cells and multinucleated giant cells were positive for T-SPOT. Clinically, tuberculous lymphadenitis and esophageal tuberculosis were suspected, with successful treatment with anti-tuberculosis therapy resulting in a good response. Our findings suggest that an EUS-FNAB is useful for diagnosing esophageal tuberculosis.
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  • 文章类型: Case Reports
    IgG4相关疾病(IgG4-RD)是一种炎性和纤维化疾病,其引起器官的肿瘤样肿胀并且通常模拟恶性肿瘤的症状。在过去的十年中,它的患病率一直在增加,但食管受累仍然很少见.IgG4-RD最初被认为涉及某些器官,比如胰腺。它有,因为,被描述为全身性疾病过程。出现吞咽困难的患者应考虑IgG4-RD。开始使用皮质类固醇进行适当的治疗可以避免不必要的手术并改善预后。本文对17例食管IgG4-RD进行综述。使用NCBI数据库(PMC和PubMed过滤器)使用关键字\“IgG4疾病,“\”硬化,\"\"食道\"和\"胃肠。“搜索范围缩小到包括使用相同过滤器描述食道IgG4疾病的病例。文献综述确定了16例记录的涉及食管的IgG4-RD病例。在文献综述中,很明显,IgG4-RD影响食道的情况极为罕见.已报告16例。我们介绍了第17例病例,并讨论了IgG4-RD的含义。对于出现吞咽困难的患者,应进行广泛的鉴别诊断,包括IgG4-RD,尤其是当症状难治时。
    IgG4-related disease (IgG4-RD) is an inflammatory and fibrosing disease which causes tumor-like swelling of organs and commonly mimics symptoms of malignancy. It has been increasing in prevalence in the last decade, but esophageal involvement remains rare. IgG4-RD was first known to involve certain organs, such as the pancreas. It has, since, been described as a systemic disease process. IgG4-RD should be considered in patients presenting with dysphagia. Initiation of appropriate treatment with corticosteroids can avoid unnecessary procedures and improve outcomes. The aim of this review is to discuss 17 cases of IgG4-RD of the esophagus. Literature review was conducted using NCBI database (PMC and PubMed filters) using the keywords \"IgG4 disease,\" \"sclerosing,\" \"esophagus\" and \"gastrointestinal.\" The search was narrowed to include cases describing IgG4 disease of the esophagus using the same filters. Literature review identified 16 documented cases of IgG4-RD involving the esophagus. Upon literature review, it remains clear that it is extremely rare for IgG4-RD to affect the esophagus. Sixteen cases have been reported. We present a 17th case and discuss the implications of IgG4-RD. It is important to keep a broad differential diagnosis that includes IgG4-RD for patients presenting with dysphagia, especially when symptoms are refractory.
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  • 文章类型: Case Reports
    Soft tissue sarcomas of the esophagus represent an extremely rare cause of esophageal masses, and an even smaller proportion of these tumors represent dedifferentiated liposarcomas. We present a case of a 75-year-old gentleman presenting with dysphagia found to have a 5 cm pedunculated mass in the cervical esophagus, originating at the cricopharyngeus. This was found to have involvement limited to the superficial mucosa by endoscopic ultrasound, and the lesion was subsequently resected endoscopically. Pathology demonstrated an undifferentiated pleomorphic sarcoma later determined to represent dedifferentiated liposarcoma after fluorescence in situ hybridization analysis. The patient received no additional adjuvant therapy and remains disease free 20 months from the procedure. While treatment experience is limited, our case demonstrates that in selected patients, sustained local control can be obtained without radical resection.
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  • 文章类型: Case Reports
    目的:回顾先天性毛状息肉的文献并描述其临床表现,操作管理,以及在反复窒息发作的新生儿中,由腭咽肌引起的先天性毛状息肉的组织学发现。
    方法:对一名2个月大的男性转诊到三级儿科医院进行图表回顾。
    结果:我们介绍了一例2个月大的男性,因反复出现窒息和呕吐而出现在急诊室。患者以前是健康的,没有既往病史或新生儿史。父母注意到患者的口咽部有一个小的肉质肿块,几分钟后他会咀嚼和吞咽。然而,体检时,没有口咽肿块的证据.患者没有呼吸窘迫。成像显示一个22×7×11mm的长方形,下颈和上胸段食管中的脂肪块,细茎向近端延伸至上塌陷的食管。术中记录的喉镜检查显示,有一个带蒂的软腭肿块附着在右上腭咽肌上。组织病理学显示,外胚层和中胚层成分呈息肉状结构,由角化鳞状上皮与附件结构和中央成熟脂肪组织衬砌,与先天性毛状息肉一致,类似于耳朵的副耳屏和分支异常。在6周的随访中,患者情况良好,体重适当增加,没有进一步窒息发作.在随访检查中没有证据表明咽喉功能障碍。手术部位完全愈合,无复发迹象。
    结论:先天性鼻和口咽毛状息肉少见,但可表现为气道或食管肿块,导致儿科患者呼吸窘迫或窒息发作。角化鳞状上皮的病理发现,附件结构,脂肪和软骨组织类似于先天性副耳屏,可能被认为是支气管弓异常。
    OBJECTIVE: To review the literature of congenital hairy polyps and describe the clinical presentation, operative management, and histologic findings of a congenital hairy polyp arising from the palatopharyngeus muscle in a neonate with recurrent choking episodes.
    METHODS: Chart review of a 2-month-old male referred to a tertiary care pediatric hospital.
    RESULTS: We present a case of a 2-month-old male who presented to the emergency room with recurrent episodes of choking and vomiting. The patient was previously healthy with no prior medical or neonatal history. The parents noted a small fleshy mass in the patient\'s oropharynx that he would chew on and swallow after several minutes. However, on physical exam, there was no evidence of oropharyngeal mass. The patient did not have respiratory distress. Imaging revealed a 22×7×11mm oblong, fatty mass in the lower cervical and upper thoracic esophagus with a thin stalk extending proximally to the upper collapsed esophagus. Intraoperative recorded laryngoscopy revealed a pedunculated soft palate mass attached to the right superior palatopharyngeus muscle. Histopathology revealed ectodermal and mesodermal elements in a polypoid structure lined by keratinizing squamous epithelium with adnexal structures and central mature adipose tissue, consistent with congenital hairy polyp resembling an accessory tragus of the ear and branchial anomaly. At 6-week follow up, the patient was doing well and gaining weight appropriately with no further choking episodes. There was no evidence of velopharyngeal dysfunction on follow up exam. The surgical site was completely healed and there was no evidence of recurrence.
    CONCLUSIONS: Congenital hairy polyps of the naso- and oropharynx are rare but may present as airway or esophageal masses, causing respiratory distress or choking episodes in a pediatric patient. The pathologic findings of keratinizing squamous epithelium, adnexal structures, adipose and cartilage tissues resemble congenital accessory tragus and may be considered a branchial arch anomaly.
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