endovascular surgery

血管内手术
  • 文章类型: Journal Article
    3D打印模型在基于模拟的训练和血管手术计划中的使用正在引起人们的兴趣。本研究旨在概述3D打印技术在血管外科中的当前应用。我们通过搜索四个数据库进行了系统评价:PubMed,WebofScience,Scopus,和Cochrane图书馆(最后搜索:2024年3月1日)。我们纳入了考虑治疗血管狭窄/闭塞性或动脉瘤疾病的研究。我们包括报告3D打印模型应用结果的论文,不包括病例报告或非常有限的病例系列(≤5个打印模型或测试/模拟)。最后,纳入并分析了22项研究。计算机断层扫描血管造影(CTA)是用于获取图像的主要诊断方法,作为生成3D打印模型的基础。处理CTA数据涉及使用医学成像软件;3DSlicer(布莱根妇女医院,哈佛大学,波士顿,MA),ITK-Snap,和模仿(物化NV,鲁汶,比利时)是最常用的。AutodeskMeshmixer(旧金山,CA,美国)和3-matic(MaterialiseNV,鲁汶,比利时)是后处理阶段最常用的网格编辑软件。PolyJet™,熔融沉积建模(FDM),和立体光刻(SLA)是最常用的3D打印技术。使用3D打印模型进行规划和培训似乎可以将医生的信心和表现水平提高多达40%,并导致手术时间和造影剂量的使用减少到不同程度。
    The use of 3D-printed models in simulation-based training and planning for vascular surgery is gaining interest. This study aims to provide an overview of the current applications of 3D-printing technologies in vascular surgery. We performed a systematic review by searching four databases: PubMed, Web of Science, Scopus, and Cochrane Library (last search: 1 March 2024). We included studies considering the treatment of vascular stenotic/occlusive or aneurysmal diseases. We included papers that reported the outcome of applications of 3D-printed models, excluding case reports or very limited case series (≤5 printed models or tests/simulations). Finally, 22 studies were included and analyzed. Computed tomography angiography (CTA) was the primary diagnostic method used to obtain the images serving as the basis for generating the 3D-printed models. Processing the CTA data involved the use of medical imaging software; 3DSlicer (Brigham and Women\'s Hospital, Harvard University, Boston, MA), ITK-Snap, and Mimics (Materialise NV, Leuven, Belgium) were the most frequently used. Autodesk Meshmixer (San Francisco, CA, USA) and 3-matic (Materialise NV, Leuven, Belgium) were the most frequently employed mesh-editing software during the post-processing phase. PolyJet™, fused deposition modeling (FDM), and stereolithography (SLA) were the most frequently employed 3D-printing technologies. Planning and training with 3D-printed models seem to enhance physicians\' confidence and performance levels by up to 40% and lead to a reduction in the procedure time and contrast volume usage to varying extents.
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  • 文章类型: Case Reports
    立体定向放射外科(SRS)治疗前庭神经鞘瘤(VS)后的动脉瘤形成是一种罕见的并发症。其特点和最佳治疗策略仍存在争议,临床过程尤其未知,因为报告的动脉瘤是首先偶然发现的,或动脉瘤破裂突然发生,他们立即得到治疗。
    一名68岁的男子在20年前接受了SRS,由于辐射引起的梭形小脑前下动脉瘤破裂,出现蛛网膜下腔出血(SAH)。他接受了母体动脉闭塞治疗,导致改良的Rankin量表等级2。该报告说明了通过回顾性磁共振成像评估在破裂前检测到动脉瘤形成的第一例。
    我们描述了动脉瘤快速进展和破裂的可能风险,专注于从SRS到动脉瘤形成的间隔。无论辐射剂量如何,SRS诱导的动脉瘤的形成时间怀疑从几年到几十年不等;然而,估计为假性动脉瘤的动脉瘤在几年内破裂的风险极高,即使尺寸很小。如果发现动脉瘤未破裂,不仅在预防SAH导致的不良预后方面有一些优势,而且在使用血运重建的可选治疗策略方面也有一些优势.长期年度随访,包括船只检查,不仅可以评估肿瘤状态,还可以早期发现任何血管病变。
    UNASSIGNED: Aneurysmal formation after stereotactic radiosurgery (SRS) for vestibular schwannoma (VS) is a rare complication. Its characteristics and the best treatment strategies remain controversial, and the clinical course is especially unknown because reported aneurysms are first incidentally detected, or aneurysmal rupture occurs suddenly, and they are treated immediately.
    UNASSIGNED: A 68-year-old man who underwent SRS for VS 20 years ago presented with subarachnoid hemorrhage (SAH) due to rupture of a radiation-induced fusiform anterior inferior cerebellar artery aneurysm. He was treated with parent artery occlusion, resulting in a modified Rankin scale grade 2. This report illustrates the first case of detected aneurysm formation before rupture with retrospective magnetic resonance imaging evaluation.
    UNASSIGNED: We describe the possible risk of rapid progression and rupture of aneurysms, focusing on the interval from SRS to aneurysmal formation. The period of formation of SRS-induced aneurysms is suspected to vary from years to decades regardless of radiation doses; however, aneurysms estimated as pseudoaneurysms have an extremely high risk of rupture within a few years, even when small in size. If aneurysms are discovered unruptured, there are some advantages in not only the prevention of poor prognosis due to SAH but also in the availability of optional therapeutic strategies using revascularization. Long-term annual follow-up, including vessel examination, is warranted not only to assess tumor status but also for early detection of any vascular lesions.
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  • 文章类型: Case Reports
    腹腔肠干(CMT),一种极其罕见的解剖变异,将腹腔动脉和肠系膜上动脉(SMA)结合在一起,具有重要的临床和手术意义。尽管它很罕见,理解这些含义对于有效管理至关重要。本报告概述了一名99岁女性出现感染性休克和腹痛的病例,成像显示附带的CMT。本文旨在通过全面的病例回顾和文献检索,阐明与CMT相关的手术意义。一名99岁的女性,患有多种心血管合并症,表现为精神状态改变和右下腹腹痛。抵达后,病人表现出迷失方向,无法服从命令,缺氧,和低血压。重要的实验室发现包括20.6x109/L的白色计数,乳酸为6.1mmol/L,53mg/dL的葡萄糖,丙氨酸转氨酶(ALT)/天冬氨酸转氨酶(AST)186/336U/L,肌酐为4.2mg/dL。即时干预涉及高流量氧气,液体复苏,静脉注射抗生素,并因感染性休克进入ICU。CT血管造影(CTA)显示附带的大共同干,包括腹腔干和肠系膜上动脉(SMA)。在SMA的起源处存在高度狭窄。然而,所有的血管在远端都有广泛的专利,排除急性肠系膜闭塞。到第12天,患者在保守治疗后达到临床稳定并出院。并发症如动脉瘤,解剖,狭窄,血栓形成,或CMT的急性闭塞可能需要复杂的手术干预,包括血管内手术或开放肝脏手术。了解这些技术复杂性对于避免危重患者的手术并发症至关重要。
    The celiacomesenteric trunk (CMT), an exceedingly rare anatomic variant uniting the celiac artery and superior mesenteric artery (SMA), holds significant clinical and surgical implications. Despite its rarity, understanding these implications is crucial for effective management. This report outlines the case of a 99-year-old female presenting with septic shock and abdominal pain, with imaging revealing an incidental CMT. This paper aims to elucidate the surgical implications associated with CMT through a comprehensive case review and literature search. A 99-year-old female with multiple cardiovascular comorbidities presented with altered mental status and right lower quadrant abdominal pain. Upon arrival, the patient exhibited disorientation, an inability to follow commands, hypoxia, and hypotension. Significant laboratory findings included a white count of 20.6 x 109/L, lactate of 6.1 mmol/L, glucose of 53 mg/dL, alanine transaminase (ALT)/aspartate aminotransferase (AST) of 186/336 U/L, and creatinine of 4.2 mg/dL. Immediate interventions involved high-flow oxygen, fluid resuscitation, intravenous antibiotics, and admission to the ICU for septic shock. A CT angiogram (CTA) revealed an incidental large common trunk comprising the celiac trunk and superior mesenteric artery (SMA). There was a high-grade stenosis at the origin of the SMA. However, all the vessels were widely patent distally, and acute mesenteric occlusion was ruled out. By day 12, the patient achieved clinical stability after conservative management and was discharged. Complications such as aneurysm, dissection, stenosis, thrombosis, or acute occlusion of a CMT may necessitate complex surgical interventions, including endovascular procedures or open hepatic surgery. Understanding these technical complexities is vital for avoiding surgical complications in critically ill patients.
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  • 文章类型: Systematic Review
    背景:治疗未破裂的脑动静脉畸形(bAVM)是重大挑战,许多不确定性仍在争论中。ARUBA试验引发了对这些病变的最佳管理策略的进一步研究。这里,我们对符合ARUBA标准的研究进行了系统评价和荟萃分析,旨在将患者数据与结果相关联,并讨论这些研究的关键方面。
    方法:遵循PRISMA指南,我们进行了系统审查。分析的变量包括bAVMSpetzler-Martin(SM)等级,治疗方式,以及死亡率和神经功能缺损等结果。我们比较了至少50%被分类为SM1-2病变的病例和少于50%的病例的研究。同样,我们对至少50%的显微手术病例和少于50%的病例进行了比较.我们检查了死亡率之间的相关性,SM分布,和治疗方式。
    结果:我们的分析包括16项研究,有2.417例患者。bAVMsSM-1-2级的频率范围从44%到76%,SM-3级从19%到48%,SM4-5从5%到23%。值得注意的是,有超过50%的SM1-2级病变病例的研究显示死亡率显著低于有少于50%的SM1-2级病变病例的研究(p<0.001).在超过50%的显微外科手术病例和少于50%的研究之间,死亡率或神经功能缺损没有显着差异。
    结论:分析显示,出现SM1-2病变的bAVM比例较高的研究与较低的死亡率相关。死亡率与治疗方式没有显着关联。
    Treating unruptured brain arteriovenous malformations (bAVMs) represent significant challenges, with numerous uncertainties still in debate. The ARUBA trial induced further investigation into optimal management strategies for these lesions. Here, we present a systematic-review and meta-analysis focusing on ARUBA-eligible studies, aiming to correlate patient data with outcomes and discuss key aspects of these studies.
    Following PRISMA guidelines, we conducted a systematic-review. Variables analyzed included bAVM Spetzler-Martin (SM) grade, treatment modalities, and outcomes such as mortality and neurological deficits. We compared studies with a minimum of 50% cases classified as SM 1-2 lesions and those with less than 50% in this category. Similarly, a comparison between studies with at least 50% microsurgery-cases and those with less than 50% was performed. We examined correlations between mortality incidence, SM distribution, and treatment modalities.
    Our analysis included 16 studies with 2.417 patients. The frequency of bAVMs SM-grade 1-2 ranged from 44% to 76%, SM-grade 3 from 19% to 48%, and SM 4-5 from 5 to 23%. Notably, studies with more than 50% cases presenting lesions SM-grade 1-2 presented significantly lower mortality rates than those with less than 50% cases of SM 1-2 lesions (P < 0.001). No significant difference in mortality rates or neurological deficits was identified between studies with more than 50% of microsurgery-cases and those with less than 50%.
    The analysis revealed that studies with a higher proportion of bAVMs presenting SM 1-2 lesions were associated with lower mortality rates. Mortality did not show a significant association with treatment modalities.
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  • 文章类型: Comparative Study
    背景:传统上通过开放修复(OR)治疗p动脉瘤(PAA)。血管内修复(ER)已成为一种新的医治战略。本系统综述和荟萃分析的目的是评估和比较OR和ER在PAA急诊治疗中的当前结果。
    方法:对PubMed/Medline数据库进行了系统的文献检索。结果是30天死亡率,发病率,主要截肢率(30天),主要截肢率(1年),1年主要通畅率,1年二次通畅率和1年生存率。此外,我们纳入了2009年至2021年在Martin-LutherUniversityHalle-Wittenberg接受治疗的pop动脉瘤患者的临床数据.
    结果:我们从2014年和2015年确定了两项队列研究,共有199例患者接受了紧急手术(39ER和160OR)。我们还包括来自我们机构的26名患者。对于紧急治疗,30天大截肢率(18%对3%,赔率比5.82,95%CI[1.75;19.30],p=.004),30天死亡率(10%对1%,赔率比5.57,95%CI[1.01;30.58],p=.05),1年主要截肢率(15%vs6%赔率3.61,95%CI[1.18;11.09],p=.02),1年原发性通畅性丧失(54%vs23%,赔率比3.19,95%CI[0.91;11.20],p=.07),和1年二次通畅性损失(44%对12%,赔率比6.91,95%CI[3.01;15.83],与OR组相比,ER组的p<0.05)更高。
    结论:腔内修复术是PAA急诊治疗的一种替代方法。来自现有非随机研究的有限证据表明,接受ER的患者预后不良。然而,结果容易出现选择偏差,只有将ER与OR进行比较的随机试验才可能揭示,在急诊情况下,ER作为PAA的主要治疗方案是否会使患者亚组受益.
    BACKGROUND: Popliteal artery aneurysms (PAA) were traditionally treated by open repair (OR). Endovascular repair (ER) has become a new treatment strategy. The aim of this systemic review and meta-analysis was to evaluate and compare the current outcomes of OR and ER in the emergency treatment of PAA.
    METHODS: A systematic literature search of the PubMed/Medline database was carried out. Outcomes were 30-day mortality, morbidity, major amputation rate (30 days), major amputation rate (1 year), 1-year primary patency rate, 1-year secondary patency rate and 1-year survival. Additionally, we included clinical data of patients with popliteal aneurysms treated between 2009 and 2021 at the Martin-Luther University Halle-Wittenberg.
    RESULTS: We identified two cohort studies from 2014 and 2015 with a total of 199 patients that underwent emergent surgery (39 ER and 160 OR). We also included 26 patients from our institution. For emergency treatment, 30-day major amputation rates (18% vs 3%, Odds Ratio 5.82, 95% CI [1.75; 19.30], p = .004), 30-day mortality rates (10% vs 1%, Odds Ratio 5.57, 95% CI [1.01; 30.58], p = .05), 1-year major amputation rates (15% vs 6% Odds Ratio 3.61, 95% CI [1.18; 11.09], p = .02), 1-year loss of primary patency (54% vs 23%, Odds Ratio 3.19, 95% CI [0.91; 11.20], p = .07), and 1-year loss of secondary patency (44% vs 12%, Odds Ratio 6.91, 95% CI [3.01; 15.83], p < .05) were higher in the ER group when compared to the OR group.
    CONCLUSIONS: Endovascular repair represents an alternative approach for the emergency treatment of PAA. Limited evidence from the available non-randomized studies shows unfavorable outcomes for patients undergoing ER. However, the results are prone to selection bias, and only randomized trials comparing ER to OR might reveal whether a subgroup of patients would benefit from ER as primary treatment of PAA in an emergency setting.
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  • 文章类型: Meta-Analysis
    这项研究的目的是描述疗效,临床结果,开放性脑血管手术的并发症,血管内手术,和减压椎基底动脉动脉瘤(DVBA)的保守治疗。
    相关文章从PubMed检索,Scopus,WebofScience,和Cochrane数据库根据PRISMA指南。对临床表现进行了荟萃分析,治疗方案,和临床结局-良好(临床状态改善或稳定)或不良(临床状态恶化或死亡)-和死亡率。
    9篇确定的文章描述了41例(27.5%)开放性脑血管手术,61例血管内手术(40.9%),和47例(31.5%)的DVBA保守管理。总队列的良好结局率为51.9%(95%CI28.3%-74.6%),不良结局率为45.5%(95%CI23.0%-70.1%),死亡率为22.3%(95%CI11.8%-38.0%)。治疗组具有相当的良好临床结局率(开放脑血管手术组:24.7%[95%CI2.9%-78.2%];血管内手术组:69.0%[95%CI28.7%-92.5%];保守治疗组:57.7%[95%CI13.0%-92.5%];p=0.19)和不良结局率(开放血管手术组:75.3%[95%CI21.8%-97.1]治疗组的死亡率也相当(开放血管手术组:39.5%[95%CI11.4%-76.8%];血管内手术组:15.8%[95%CI4.4%-43.0%];保守治疗组:19.2%[95%CI6.8%-43.5%];p=0.23)。
    目前对DVBA的研究表明,无论采用何种治疗方式,结果都差,死亡率高。亚组分析显示亚组之间的异质性和个性化管理建议。
    The aim of this study was to describe the efficacy, clinical outcomes, and complications of open cerebrovascular surgery, endovascular surgery, and conservative management of dolichoectatic vertebrobasilar aneurysms (DVBAs).
    Relevant articles were retrieved from PubMed, Scopus, Web of Science, and Cochrane databases according to PRISMA guidelines. A meta-analysis was conducted for clinical presentation, treatment protocols, and clinical outcomes-good (improved or stable clinical status) or poor (deteriorated clinical status or death)-and mortality rates.
    The 9 identified articles described 41 cases (27.5%) of open cerebrovascular surgery, 61 endovascular procedures (40.9%), and 47 cases (31.5%) of conservative management for DVBAs. The total cohort had a good outcome rate of 51.9% (95% CI 28.3%-74.6%), a poor outcome rate of 45.5% (95% CI 23.0%-70.1%), and a mortality rate of 22.3% (95% CI 11.8%-38.0%). The treatment groups had comparable good clinical outcome rates (open cerebrovascular surgery group: 24.7% [95% CI 2.9%-78.2%]; endovascular surgery group: 69.0% [95% CI 28.7%-92.5%]; conservative management group: 57.7% [95% CI 13.0%-92.5%]; p = 0.19) and poor outcome rates (open vascular surgery group: 75.3% [95% CI 21.8%-97.1%]; endovascular surgery group: 27.2% [95% CI 5.6%-0.70.2%]; conservative management group: 39.9% [95% CI 9.1%-81.6%]; p = 0.15). The treatment groups also had comparable mortality rates (open vascular surgery group: 39.5% [95% CI 11.4%-76.8%]; endovascular surgery group: 15.8% [95% CI 4.4%-43.0%]; conservative management group: 19.2% [95% CI 6.8%-43.5%]; p = 0.23).
    The current study of DVBAs illustrated poor outcomes and high mortality rates regardless of the treatment modality. The subgroup analysis showed heterogeneity among the subgroups and advice for personalized management.
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  • 文章类型: Review
    硬脑膜窦畸形(DSMs)是罕见的先天性血管疾病,其特征是有或没有动静脉分流的巨大静脉袋。我们介绍了一例DSM的新生儿病例,该病例是在产前诊断的,并在出生后早期通过血管内介入治疗。患者出现大型DSM,涉及环形Herophilion产前磁共振成像(MRI)。出生后头围增大和呼吸衰竭迅速发展。出生后第5天,新生儿经脐动脉血管内闭塞.动静脉分流阻塞,从扩大的静脉囊到硬脑膜窦的回流减少。除脑室腹膜分流术外,不需要其他手术。新生儿的发育慢慢赶上正常参数。随访MRI证明了静脉引流系统的成功开发。DSM的特征是硬脑膜窦异常扩张,可以阻断静脉回流,最终增加颅内压和脑缺血。长期随访表明,通过适当和及时的治疗可以重建异常发育的硬脑膜窦。
    Dural sinus malformations (DSMs) are rare congenital vascular diseases characterized by a giant venous pouch with or without arteriovenous shunts. We present a neonatal case of DSM that was diagnosed prenatally and treated via endovascular intervention in the early postnatal period. The patient presented with a large DSM involving the torcular Herophilion prenatal magnetic resonance imaging (MRI). Enlargement of the head circumference and respiratory failure rapidly progressed after birth. On the 5th day after birth, the neonate underwent endovascular occlusion via the umbilical artery. The arteriovenous shunt was occluded, and the reflux from the enlarged venous pouch to the dural sinus was decreased. No additional procedure other than ventriculoperitoneal shunting was required. The neonate\'s development slowly caught up to normal parameters. Follow-up MRI demonstrated the successful development of the venous drainage system. DSMs are characterized by an abnormally dilated dural sinus, which can block the venous return and ultimately increase intracranial pressure and cerebral ischemia. Long-term follow-up indicates that an abnormally developed dural sinus can be reconstructed by appropriate and timely treatment.
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  • 文章类型: Journal Article
    手外科医师在临床实践中经常遇到手和上肢(HUE)血管疾病。对于HUE血管疾病的诊断和治疗,存在广泛的成像和血管介入放射学模式。HUE外科医生可能不熟悉其中的一些。在这篇评论文章中,我们总结了血管成像和血管介入放射学模式及其相对优势,缺点,以及HUE病理学的适应症。我们的目标是使HUE外科医生熟悉HUE血管病变的可用诊断和治疗选择类型,并在临床决策过程中帮助与血管介入放射学专家进行跨学科交流。
    Hand and upper extremity (HUE) vascular disorders are encountered frequently by hand surgeons in clinical practice. A wide array of imaging and vascular interventional radiology modalities exists for the diagnosis and treatment of HUE vascular disorders, some of which may not be familiar to the HUE surgeons. In this review article, we summarize the vascular imaging and vascular interventional radiology modalities and their relative advantages, disadvantages, and indications with respect to HUE pathology. We aim to familiarize HUE surgeons with the available types of diagnostic and therapeutic options for HUE vascular pathologies and aid interdisciplinary communication with vascular interventional radiology specialists during the clinical decision-making process.
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  • 文章类型: Journal Article
    生物医学工程将各种应用科学与生命科学相结合,以改善人类健康并减少外科手术的侵入性。技术进步,通过生物医学工程实现,为血管和血管内手术领域的重大改进做出了贡献。本文旨在回顾过去十年中涉及在血管手术中使用增强现实设备和机器人系统的尖端技术,突出优点和局限性。因此,通过PubMed数据库进行了两次不同的文献调查:第一次审查提供了对增强现实技术的全面评估,包括可用于虚拟内容可视化的不同技术(11篇论文修订);第二篇综述收集了具有生物工程内容的研究,突出了机器人血管手术的研究趋势,不包括仅专注于商用机器人系统的临床使用的工作(修订了15篇论文)。技术流程是不变的,成像技术和硬件组件的进一步进步将不可避免地带来新的工具,用于血管外科创新治疗策略的临床翻译。
    Biomedical engineering integrates a variety of applied sciences with life sciences to improve human health and reduce the invasiveness of surgical procedures. Technological advances, achieved through biomedical engineering, have contributed to significant improvements in the field of vascular and endovascular surgery. This paper aims to review the most cutting-edge technologies of the last decade involving the use of augmented reality devices and robotic systems in vascular surgery, highlighting benefits and limitations. Accordingly, two distinct literature surveys were conducted through the PubMed database: the first review provides a comprehensive assessment of augmented reality technologies, including the different techniques available for the visualization of virtual content (11 papers revised); the second review collects studies with bioengineering content that highlight the research trend in robotic vascular surgery, excluding works focused only on the clinical use of commercially available robotic systems (15 papers revised). Technological flow is constant and further advances in imaging techniques and hardware components will inevitably bring new tools for a clinical translation of innovative therapeutic strategies in vascular surgery.
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  • 文章类型: Journal Article
    外科技术的最新进展,减少工作时间,和COVID-19大流行加剧的培训机会导致基于模拟的培训增加。此外,血管内手术的增加导致需要提供全面反馈的高保真模拟器.这篇综述旨在确定血管手术模拟模型,并评估其有效性和每个模型的有效性(LoE)水平,以便将其成功实施到当前的培训课程中。
    在2021年1月1日搜索了PubMed和EMBASE,以获取有关血管手术模拟器的全文英文研究。根据Messick的现代有效性概念以及根据McGaghie的翻译结果的LoE评分,对符合条件的文章进行有效性评级。
    总共76篇符合条件的文章验证了34个开放和血管内手术的血管手术模拟器和培训课程。在以下方面的研究中获得了高有效性评级:内容(35),响应过程(12),内部结构(5),与其他变量的关系(57),后果(2)。只有7项研究获得了大于3/5的LoE。总的来说,ANGIOMentor是最高度验证和有效的模拟器,并且是唯一实现5/5LoE的模拟器。
    基于模拟的血管外科培训是一个不断发展的领域,具有令人兴奋的未来前景,展示了大量的模型和培训课程。为了有效地将仿真模型集成到当前的血管外科手术课程和评估中,有必要进行研究,以研究在更长的时间内保留受训者的技能。还需要对成本效益进行更详细的讨论。
    Recent advancements in surgical technology, reduced working hours, and training opportunities exacerbated by the COVID-19 pandemic have led to an increase in simulation-based training. Furthermore, a rise in endovascular procedures has led to a requirement for high-fidelity simulators that offer comprehensive feedback. This review aims to identify vascular surgery simulation models and assess their validity and levels of effectiveness (LoE) for each model in order to successfully implement them into current training curricula.
    PubMed and EMBASE were searched on January 1, 2021, for full-text English studies on vascular surgery simulators. Eligible articles were given validity ratings based on Messick\'s modern concept of validity alongside an LoE score according to McGaghie\'s translational outcomes.
    Overall 76 eligible articles validated 34 vascular surgery simulators and training courses for open and endovascular procedures. High validity ratings were achieved across studies for: content (35), response processes (12), the internal structure (5), relations to other variables (57), and consequences (2). Only seven studies achieved an LoE greater than 3/5. Overall, ANGIO Mentor was the most highly validated and effective simulator and was the only simulator to achieve an LoE of 5/5.
    Simulation-based training in vascular surgery is a continuously developing field with exciting future prospects, demonstrated by the vast number of models and training courses. To effectively integrate simulation models into current vascular surgery curricula and assessments, there is a need for studies to look at trainee skill retention over a longer period of time. A more detailed discussion on cost-effectiveness is also needed.
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