多器官/播散性包虫病在儿童时期很少见。我们旨在评估患有多器官/播散性包虫病的儿科患者的临床和实验室特征以及预后。
我们回顾性评估了累及三个或更多器官的包虫病患儿。
13名患者被纳入研究。中位年龄为120(范围71-189)个月。三个(23%)是偶然诊断的。5例(38.4%)患者出现腹痛,4人呕吐(30.7%),头痛3例(23%),咳嗽2例(15.3%),1例腹股沟疼痛(7.6%),1例(7.6%)有黄疸,1例(7.6%)有发热。投诉的中位持续时间为48(0-140)天。最常见的三部分器官为38.4%(5/13)肝脏,肺和脾。在两名患者中检测到孤立的腹部播散。两名患者多器官受累,多个囊肿伴播散。在3例患者中观察到囊肿破裂;复发性尿路感染,输尿管肾积水,继发性腹膜炎伴腹内脓肿,胆道瘘各观察1例。3例(23%)患者出现复发。
棘球蚴病是一种生长缓慢且复杂的寄生虫病,影响许多器官和组织。在我们的研究中,嗜酸性粒细胞增多,复发,在多器官受累的儿科患者中,并发症的发生率更高,他们需要重复手术和长期医疗。然而,关于风险因素的数据很少,最佳治疗和预后。
Echinococcosis with multi-organ/
disseminated involvement is rare in childhood. We aimed to evaluate the clinical and laboratory characteristics and prognosis in paediatric patients with echinococcosis having multiorgan/
disseminated involvement.
We evaluated retrospectively children with echinococcosis with involvement of three or more organs.
Thirteen patients were included in the study. The median age was 120 (range 71-189) months. Three (23%) were diagnosed incidentally. Abdominal pain was seen in 5 (38.4%) patients, vomiting in 4 (30.7%), headache in 3 (23%), cough in 2 (15.3%), groin pain in 1 (7.6%), 1 (7.6%) had jaundice and 1 (7.6%) had fever. The median duration of complaints was 48 (0-140) days. The most common tripartite organ was 38.4% (5/13) liver, lung and spleen. Isolated abdominal dissemination was detected in two patients. Two patients had multi-organ involvement and multiple cysts with dissemination. Cyst rupture was observed in three of the patients; recurrent urinary tract infection, hydroureteronephrosis, secondary peritonitis with intra-abdominal abscess, and biliary tract fistula were each observed in one patient. Relapse developed in 3 (23%) patients.
Echinococcosis is a very slow growing and complex parasitic disease that affects many organs and tissues. In our study, eosinophilia, recurrence, and complications were seen at a higher rate in paediatric patients with multiorgan involvement, who required repetitive surgeries and long-term medical treatment. However, there are scanty data on risk factors, optimum treatment and prognosis.