基于人类干细胞的建模系统是有价值的工具,可以大大提高基础研究的临床翻译。重要的是,基于人类干细胞的模型在生物医学研究中的成功应用取决于道德原则和实践标准的广泛采用。为了实现这一结果,国际干细胞研究协会(ISSCR)提供了一套全面的建议,旨在促进人类干细胞的伦理使用,并确保该领域的严密性和可重复性。理解和实施这些建议应该是世界各地调查人员的首要任务。
Human stem cell-based modeling systems are valuable tools that can greatly improve the clinical translation of basic research. Importantly, the successful application of human stem cell-based models to biomedical research depends on the widespread adoption of ethical principles and practical standards. To achieve this outcome, the International Society for Stem Cell Research (ISSCR) provides a comprehensive set of recommendations that aim to promote the ethical usage of human stem cells and to ensure rigor and reproducibility within the field. Understanding and implementing these recommendations should be a top priority for investigators around the world.