ct imaging

CT 成像
  • 文章类型: Case Reports
    我们描绘了一个独特的病例,一名39岁的妇女向急诊科就诊,抱怨右上腹疼痛。检查和计算机断层扫描(CT)扫描显示急性胆囊炎,患者接受了腹腔镜胆囊切除术,无并发症。此时,在腹壁附近的皮下脂肪中发现了一个偶然的肿块。6个月后病人回来了,她上次住院后出现周期性腹痛.初次入院实验室工作在正常范围内,尿液妊娠试验为阴性。体格检查显示她先前的剖宫产疤痕周围有压痛。重复CT显示增大,针状团块粘附于腹壁。成像确认后,患者接受了完全开放的手术切除,以去除肿块。术后活检证实子宫内膜腺及间质与腹壁子宫内膜瘤一致。患者接受辅助治疗后出院,并建议外科医生和她的妇产科医生进行随访。放射学诊断,指导方针,本报告讨论了开始介入治疗的决策。我们记录此病例的目的是为腹壁子宫内膜瘤的非典型位置提供罕见的诊断,在先前剖宫产的患者中。尽管这名患者接受了开放切除术,讨论了射频消融和聚焦超声的不同介入放射学治疗方法。在这样做的时候,我们希望为关于手术切除作为Pfannenstiel切口子宫内膜瘤治疗选择的系统文献综述做出贡献.
    We depict a unique case of a 39-year-old woman who presented to the emergency department with complaints of right upper quadrant pain. Work-up and a computed tomography (CT) scan revealed acute cholecystitis and the patient underwent laparoscopic cholecystectomy without complication. At this time, an incidental mass was discovered in the subcutaneous fat adjacent to the abdominal wall. The patient returned six months later with progressive, cyclic abdominal pain since her last hospital admission. Initial admission lab work was within normal limits and a urine pregnancy test was negative. Physical exam revealed tenderness around her previous cesarean section scar. Repeat CT revealed an enlarging, spiculated mass adherent to the abdominal wall. After imaging confirmation, the patient underwent complete open surgical excision for the removal of the mass. Post-surgical biopsy confirmed endometrial gland and stroma consistent with abdominal wall endometrioma. The patient was discharged with adjuvant therapy and recommended follow-up with the surgeon and her obstetrician-gynecologist. The radiological diagnosis, guidelines, and decision-making for initiating interventional treatment are discussed in this report. Our purpose in documenting this case is to present a rare diagnosis of an atypical location for an endometrioma on the abdominal wall, in a patient with prior cesarean delivery. Although this patient was treated with open excision, different interventional radiology treatments from radiofrequency ablation and focused ultrasound were discussed. In doing so, we hope to contribute to the systematic literature review on surgical excision as a treatment option for Pfannenstiel incision endometrioma.
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  • 文章类型: Journal Article
    2019年冠状病毒病(COVID-19)肺炎在全球范围内产生了灾难性影响。放射学,特别是计算机断层扫描(CT)成像,已经证明在诊断中很有价值,预测,并对诊断为COVID-19肺炎的患者进行纵向评估。本文将回顾COVID-19肺炎的急性和慢性肺部放射学表现,重点是CT和组织病理学,相关临床细节,以及解读文学时的一些显著挑战。
    Coronavirus disease 2019 (COVID-19) pneumonia has had catastrophic effects worldwide. Radiology, in particular computed tomography (CT) imaging, has proven to be valuable in the diagnosis, prognostication, and longitudinal assessment of those diagnosed with COVID-19 pneumonia. This article will review acute and chronic pulmonary radiologic manifestations of COVID-19 pneumonia with an emphasis on CT and also highlighting histopathology, relevant clinical details, and some notable challenges when interpreting the literature.
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  • 文章类型: Case Reports
    直肠癌向骨骼肌转移是罕见的。自1970年以来,只有30例起源于结直肠腺癌的骨骼肌转移被记录,强调其极低的发病率。这里,我们介绍了一个中年男子的病例,他在3个月前被诊断为直肠腺癌。考试期间,在左臀部近端发现皮下肿块。活检的组织学分析证实,该肿块是源于原发性直肠腺癌的转移性病变。
    Rectal carcinoma with metastasis to skeletal muscle is a rare occurrence. Since 1970, only 30 cases of skeletal muscle metastasis originating from colorectal adenocarcinomas have been documented, underscoring its exceptionally low incidence. Here, we present the case of a middle-aged man who was diagnosed with rectal adenocarcinoma 3 months ago. During examination, a subcutaneous mass was discovered in the left proximal buttock. Histological analysis of a biopsy confirmed that this mass was a metastatic lesion originating from the primary rectal adenocarcinoma.
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  • 文章类型: Journal Article
    背景:Stercoral结肠炎(SC)是一种罕见但可能危及生命的炎症性结肠炎,由受累粪便物质的积累引起。尽管据报道与肠穿孔和高死亡率有关,在急诊科(ED),结肠病仍然是一个不明确且未得到充分认可的诊断.
    目的:这篇综述旨在总结和综合有关SC的现有文献,以指导其在ED中的认可和管理。
    结论:SC主要发生于老年或卧床慢性便秘患者;然而,它确实发生在合并有粪便嵌塞风险增加的年轻患者中。患者可能会出现剧烈的腹痛和腹胀,但是临床表现通常是非特异性和多样性的,迄今为止,尚无SC的既定诊断标准。因此CT对诊断至关重要,揭示了关键的发现,如Fecaloma,结肠扩张,和脂肪绞合。治疗取决于疾病的严重程度,在大多数情况下,从手动干预和其他保守措施不等,复杂病例的手术干预,如类珊瑚穿孔。
    结论:SC可能是ED中具有挑战性的诊断,通常需要多学科合作。及时识别和适当的治疗对于降低与这种情况相关的发病率和死亡率至关重要。需要进一步的研究来建立诊断标准和明确的管理算法。
    BACKGROUND: Stercoral colitis (SC) is a rare but potentially life-threatening inflammatory colitis caused by the accumulation of impacted fecal material. Despite reported associations with bowel perforation and high mortality rates, stercoral colitis remains a poorly defined and underrecognized diagnosis in the emergency department (ED).
    OBJECTIVE: This review aims to summarize and synthesize existing literature on SC to guide its recognition and management in the ED.
    CONCLUSIONS: SC primarily occurs in elderly or bedbound patients with chronic constipation; however, it does occur in younger patients with comorbidities at increased risk for fecal impaction. Patients may present acutely with abdominal pain and distension, but clinical presentation is often nonspecific and varied, and there are no established diagnostic criteria for SC to date. CT is therefore crucial for diagnosis, revealing key findings such as fecaloma, colonic dilatation, and fat stranding. Treatment depends on severity of illness, ranging from manual disimpaction and other conservative measures for most cases, to surgical intervention for complicated cases, such as stercoral perforation.
    CONCLUSIONS: SC can be a challenging diagnosis in the ED, often requiring multidisciplinary collaboration. Timely recognition and appropriate treatment are essential to reduce morbidity and mortality associated with this condition. Further research is needed to establish diagnostic criteria and clear management algorithms.
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  • 文章类型: Meta-Analysis
    本系统综述的目的是基于现有的关于初始CT成像预测儿科患者严重创伤性脑损伤(TBI)死亡率的能力的研究,分析证据。一位经验丰富的图书馆员根据纳入和排除标准搜索了所有现有研究。这些研究由两名失明的评论者进行筛选。在搜索中包含的3277项研究中,影像学检查结果的患病率和死亡率的数据只能从22项研究中提取.其中一些研究具有患者特定的数据,将特定的影像学发现与结果相关,允许数据分析,曲线下面积(AUC)和受试者工作特性(ROC)的计算,并为每个发现生成一个森林地块。提取数据以计算灵敏度(SN),特异性(SP),阳性预测值(PPV),负预测值(NPV),AUC,和ROC用于硬膜外血肿(EDH),硬膜下血肿(SDH),外伤性蛛网膜下腔出血(tSAH),颅骨骨折,和水肿。共有2219名患者,747名女性和1461名男性。在总数中,564例患者死亡,1651例存活;293例患者患有SDH,76有EDH,347有tSAH,244例颅骨骨折,416有水肿。纳入的研究具有较高的偏倚性和较低的证据等级。在不同的CT扫描结果中,脑水肿的SN最高,PPV,NPV,AUC。EDH具有最高的SP来预测住院死亡率。
    The purpose of this systematic review was to analyze evidence based on existing studies on the ability of initial CT imaging to predict mortality in severe traumatic brain injuries (TBIs) in pediatric patients. An experienced librarian searched for all existing studies based on the inclusion and exclusion criteria. The studies were screened by two blinded reviewers. Of the 3277 studies included in the search, data on prevalence of imaging findings and mortality rate could only be extracted from 22 studies. A few of those studies had patient-specific data relating specific imaging findings to outcome, allowing the data analysis, calculation of the area under the curve (AUC) and receiver operating characteristic (ROC), and generation of a forest plot for each finding. The data were extracted to calculate the sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predicted value (NPV), AUC, and ROC for extradural hematoma (EDH), subdural hematoma (SDH), traumatic subarachnoid hemorrhage (tSAH), skull fractures, and edema. There were a total of 2219 patients, 747 females and 1461 males. Of the total, 564 patients died and 1651 survived; 293 patients had SDH, 76 had EDH, 347 had tSAH, 244 had skull fractures, and 416 had edema. The studies included had high bias and lower grade of evidence. Out of the different CT scan findings, brain edema had the highest SN, PPV, NPV, and AUC. EDH had the highest SP to predict in-hospital mortality.
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  • 文章类型: Journal Article
    自2020年以来,新型冠状病毒肺炎在全球迅速蔓延,给医院的医疗诊断和治疗带来巨大压力。医学成像方法,如计算机断层扫描(CT),在诊断和治疗COVID-19中起着至关重要的作用。在基于CT的医学诊断期间产生大量CT图像(具有大体积)。在这种情况下,人眼对上千张CT图像的诊断判断是低效且耗时的。最近,为了提高诊断效率,机器学习技术正被广泛应用于计算机辅助诊断和治疗系统(即,CT成像),以帮助医生进行准确的分析,并为他们提供有效的诊断决策支持。在本文中,我们全面回顾了这些常用的机器学习方法在COVID-19CT成像诊断中的应用,从图像采集和预处理等各个方面讨论了基于机器学习的应用,图像分割,定量分析和诊断,以及疾病随访和预后。此外,我们还讨论了最新的机器学习技术在CT成像计算机辅助诊断中的局限性.
    Since 2020, novel coronavirus pneumonia has been spreading rapidly around the world, bringing tremendous pressure on medical diagnosis and treatment for hospitals. Medical imaging methods, such as computed tomography (CT), play a crucial role in diagnosing and treating COVID-19. A large number of CT images (with large volume) are produced during the CT-based medical diagnosis. In such a situation, the diagnostic judgement by human eyes on the thousands of CT images is inefficient and time-consuming. Recently, in order to improve diagnostic efficiency, the machine learning technology is being widely used in computer-aided diagnosis and treatment systems (i.e., CT Imaging) to help doctors perform accurate analysis and provide them with effective diagnostic decision support. In this paper, we comprehensively review these frequently used machine learning methods applied in the CT Imaging Diagnosis for the COVID-19, discuss the machine learning-based applications from the various kinds of aspects including the image acquisition and pre-processing, image segmentation, quantitative analysis and diagnosis, and disease follow-up and prognosis. Moreover, we also discuss the limitations of the up-to-date machine learning technology in the context of CT imaging computer-aided diagnosis.
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  • 文章类型: Journal Article
    光子计数计算机断层扫描(CT)是一种技术,近年来引起了越来越多的兴趣,多亏了新一代探测器,它有望从根本上改变CT成像的临床应用。光子计数探测器通过提供非常高的空间分辨率而没有电子噪声,克服了传统CT探测器的主要局限性。提供更高的对比度与噪声比,并优化光谱图像。此外,光子计数CT可以减少辐射暴露,重建更高空间分辨率的图像,减少图像伪影,优化造影剂的使用,并为定量成像创造新的机会。这篇综述的目的是简要解释光子计数CT的技术原理,更广泛的,该技术的潜在临床应用。
    Photon-counting computed tomography (CT) is a technology that has attracted increasing interest in recent years since, thanks to new-generation detectors, it holds the promise to radically change the clinical use of CT imaging. Photon-counting detectors overcome the major limitations of conventional CT detectors by providing very high spatial resolution without electronic noise, providing a higher contrast-to-noise ratio, and optimizing spectral images. Additionally, photon-counting CT can lead to reduced radiation exposure, reconstruction of higher spatial resolution images, reduction of image artifacts, optimization of the use of contrast agents, and create new opportunities for quantitative imaging. The aim of this review is to briefly explain the technical principles of photon-counting CT and, more extensively, the potential clinical applications of this technology.
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  • 文章类型: Journal Article
    COVID-19,一种新的呼吸道传染病,于2019年底在武汉首次报道,中国。现在,COVID-19仍然在世界几乎所有国家造成人类生命和经济生产力的重大损失。及早发现,早期隔离,和COVID-19患者和无症状携带者的早期诊断对于阻断大流行的传播至关重要。本文简要回顾了COVID-19诊断试验的临床应用,包括核酸检测,免疫学方法,和计算机断层扫描(CT)成像。核酸测试(NAT)靶向病毒基因组并指示SARS-CoV-2病毒的存在。目前,实时定量PCR(qPCR)是应用最广泛的NAT,基本上,是COVID-19最常用的诊断方法。除了qPCR,还开发了许多新颖的快速和灵敏的NAT测定。血清学检测(SARS-CoV-2特异性血清抗体检测),属于免疫学方法,也用于诊断COVID-19。血清学测试的阳性结果表明存在因感染该病毒而导致的对SARS-CoV-2具有特异性的抗体。病毒抗原检测试验也是主要用于快速病毒检测的重要免疫学方法。然而,仅报道了其中一些检测方法。CT成像仍是COVID-19患者重要的辅助诊断工具,特别是早期有症状的患者,其病毒载量较低且不同,可通过NAT识别。这些诊断技术在某种程度上都很好,将它们结合使用将大大提高COVID-19诊断的准确性。
    COVID-19, a new respiratory infectious disease, was first reported at the end of 2019, in Wuhan, China. Now, COVID-19 is still causing major loss of human life and economic productivity in almost all countries around the world. Early detection, early isolation, and early diagnosis of COVID-19 patients and asymptomatic carriers are essential to blocking the spread of the pandemic. This paper briefly reviewed COVID-19 diagnostic assays for clinical application, including nucleic acid tests, immunological methods, and Computed Tomography (CT) imaging. Nucleic acid tests (NAT) target the virus genome and indicates the existence of the SARS-CoV-2 virus. Currently, real-time quantitative PCR (qPCR) is the most widely used NAT and, basically, is the most used diagnostic assay for COVID-19. Besides qPCR, many novel rapid and sensitive NAT assays were also developed. Serological testing (detection of serum antibodies specific to SARS-CoV-2), which belongs to the immunological methods, is also used in the diagnosis of COVID-19. The positive results of serological testing indicate the presence of antibodies specific to SARS-CoV-2 resulting from being infected with the virus. Viral antigen detection assays are also important immunological methods used mainly for rapid virus detection. However, only a few of these assays had been reported. CT imaging is still an important auxiliary diagnosis tool for COVID-19 patients, especially for symptomatic patients in the early stage, whose viral load is low and different to be identified by NAT. These diagnostic techniques are all good in some way and applying a combination of them will greatly improve the accuracy of COVID-19 diagnostics.
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  • 文章类型: Journal Article
    背景:气胸(PTX)定义为胸膜腔中的空气,分为自发性或非自发性(创伤性)。创伤性PTX是急诊科确定的常见病理。传统的管理要求胸部X线(CXR)诊断和大口径导管胸廓造口术,尽管最近的文献支持肺超声(US)和更保守的方法的疗效。关于如何最好地管理创伤性PTX,缺乏有凝聚力的文献。
    这篇综述旨在描述创伤PTX管理的当前实践和未来方向。
    结论:与CXR相比,肺US已被证明是检测创伤湾中PTX的潜在更有用的工具,并有可能成为诊断创伤性PTX的新黄金标准。计算机断层扫描仍然是最终的黄金标准,尽管在创伤的背景下,它的效用更多地在于确认PTX的存在和测量其大小。传统的口头禅要求大口径胸管作为创伤性PTX的一线方法受到最近文献的挑战,这些文献证明猪尾导管是同样有效的替代品。在患有小型或隐匿性PTX的患者中,甚至观察也可能是合理的。
    结论:创伤性PTX的现代管理正在转向使用US进行诊断和更保守的管理实践(较小的导管或观察)。最终,这种转变有利于减少停留时间,并发症的发展,创伤患者的疼痛。
    BACKGROUND: Pneumothorax (PTX) is defined as air in the pleural space and is classified as spontaneous or nonspontaneous (traumatic). Traumatic PTX is a common pathology identified in the emergency department. Traditional management calls for chest x-ray (CXR) diagnosis and large-bore tube thoracostomy, although recent literature supports the efficacy of lung ultrasound (US) and more conservative approaches. There is a paucity of cohesive literature on how to best manage the traumatic PTX.
    UNASSIGNED: This review aimed to describe current practices and future directions of traumatic PTX management.
    CONCLUSIONS: Lung US has proven to be a potentially more useful tool in the detection of PTX in the trauma bay compared with CXR, and has the potential to become the new gold standard for diagnosing traumatic PTX. Computed tomography remains the ultimate gold standard, although in the setting of trauma, its utility lies more in confirming the presence and measuring the size of a PTX. The traditional mantra calling for large-bore chest tubes as first-line approaches to traumatic PTX is challenged by recent literature demonstrating pigtail catheters as equally efficacious alternatives. In patients with small or occult PTXs, even observation may be reasonable.
    CONCLUSIONS: Modern management of the traumatic PTX is shifting toward use of US for diagnosis and more conservative management practices (smaller catheters or observation). Ultimately, this shift is favorable in reducing length of stay, development of complications, and pain in the trauma patient.
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  • 文章类型: Journal Article
    OBJECTIVE: The aim of this systematic review was to identify, review, analyze, and summarize available evidence on the accuracy of linear measurements when using maxillofacial cone beam computed tomography (CBCT) specifically in the field of implant dentistry.
    METHODS: The search was undertaken in April 2017 in the National Library of Medicine database (Medline) through its online site (PubMed), followed by searches in the Cochrane, EMBASE, ScienceDirect, and ProQuest Dissertation and Thesis databases. The main inclusion criterion for studies was that linear CBCT measurements were performed for quantitative assessment (e.g., height, width) of the alveolar bone at edentulous sites or measuring distances from anatomical structures related to implant dentistry. The studies should compare these values to clinical data (humans) or ex vivo and/or experimental (animal) findings from a \"gold standard.\"
    RESULTS: The initial search yielded 2,516 titles. In total, 22 studies were included in the final analysis. Of those, two were clinical and 20 ex vivo investigations. The major findings of the review indicate that CBCT provides cross-sectional images that demonstrate high accuracy and reliability for bony linear measurements on cross-sectional images related to implant treatment. A wide range of error has been reported when performing linear measurements on CBCT images, with both over- and underestimation of dimensions in comparison with a gold standard. A voxel size of 0.3 to 0.4 mm is adequate to provide CBCT images of acceptable diagnostic quality for implant treatment planning.
    CONCLUSIONS: CBCT can be considered as an appropriate diagnostic tool for 3D preoperative planning. Nevertheless, a 2 mm safety margin to adjacent anatomic structures should be considered when using CBCT. In clinical practice, the measurement accuracy and reliability of linear measurements on CBCT images are most likely reduced through factors such as patient motion, metallic artefacts, device-specific exposure parameters, the software used, and manual vs. automated procedures.
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