ct angiography

CT 血管造影
  • 文章类型: Case Reports
    一种罕见的局部侵袭性血管肿瘤,青少年鼻咽血管纤维瘤(JNA)主要影响男性青少年。本文描述了一名14岁的男性患者,他表现为嗜睡和复发性鼻出血,这是JNA的症状。CT和MRI扫描证实血管肿块具有明显的局部侵袭,起源于蝶腭孔。CT血管造影后,这揭示了肿瘤的大量血液供应,并有助于有效切除,设计了一个有针对性的手术策略。组织病理学证实了肿瘤的良性性质,手术成功,患者顺利康复。这个案例增加了关于JNA的小文献。它强调了医疗保健专业人员在管理疾病时需要了解早期识别和仔细的术前准备的要求。
    A rare and locally aggressive vascular tumor, juvenile nasopharyngeal angiofibroma (JNA) mostly affects male teenagers. This paper describes a 14-year-old male patient who presented with lethargy and recurrent nasal bleeding, which are symptoms of JNA. CT and MRI scans confirmed a vascular mass with a significant local invasion originating from the sphenopalatine foramen. After a CT angiography, which revealed the tumor\'s large blood supply and helped with efficient excision, a focused surgical strategy was designed. Histopathology verified the benign nature of the tumor, and the operation was successful and the patient had a smooth recovery. This case adds to the little literature on JNA. It highlights the need for healthcare professionals to be aware of the requirement of early identification and careful presurgical preparation in managing the illness.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:血管内动脉瘤修复术(EVAR)后的计算机断层扫描血管造影(CTA)图像的图像质量不令人满意,由于金属植入物造成的伪影阻碍了支架和隔离腔的清晰描绘,以及邻近的软组织。然而,由于更高的辐射剂量,目前减少这些伪影的技术仍需要进一步的进步,更长的处理时间等等。因此,这项研究的目的是评估利用单能量金属工件减少(SEMAR)以及一种新颖的深度学习图像重建技术的影响,被称为高级智能Clear-IQ引擎(AiCE),EVAR后CTA随访的图像质量。
    方法:这项回顾性研究包括47例患者(平均年龄±标准差:68.6±7.8岁;37例男性),他们在EVAR后接受了CTA检查。使用四种不同的方法重建图像:混合迭代重建(HIR),AICE,HIR和SEMAR的组合(HIR+SEMAR),以及AiCE和SEMAR的组合(AiCE+SEMAR)。两个放射科医生,对重建技术视而不见,独立评估图像。定量评估包括图像噪声的测量,信噪比(SNR),对比噪声比(CNR),工件的最长长度(AL),和工件索引(AI)。随后在不同的重建方法中比较这些参数。
    结果:主观结果表明,AiCE+SEMAR在图像质量方面表现最好。AiCE+SEMAR组的平均图像噪声强度(25.35±6.51HU)明显低于HIR组(47.77±8.76HU),AiCE(42.93±10.61HU),和HIR+SEMAR(30.34±4.87HU)组(p<0.001)。此外,AiCE+SEMAR展示了最高的SNR和CNR,以及最低的AIs和AL。重要的是,使用AiCE+SEMAR最清楚地观察到内漏和血栓。
    结论:与其他重建方法相比,AiCE+SEMAR的组合展示了卓越的图像质量,从而提高了潜在并发症的检测能力和诊断信心,例如EVAR后的早期小端漏和血栓。图像质量的这种改善可以导致更准确的诊断和更好的患者结果。
    BACKGROUND: The image quality of computed tomography angiography (CTA) images following endovascular aneurysm repair (EVAR) is not satisfactory, since artifacts resulting from metallic implants obstruct the clear depiction of stent and isolation lumens, and also adjacent soft tissues. However, current techniques to reduce these artifacts still need further advancements due to higher radiation doses, longer processing times and so on. Thus, the aim of this study is to assess the impact of utilizing Single-Energy Metal Artifact Reduction (SEMAR) alongside a novel deep learning image reconstruction technique, known as the Advanced Intelligent Clear-IQ Engine (AiCE), on image quality of CTA follow-ups conducted after EVAR.
    METHODS: This retrospective study included 47 patients (mean age ± standard deviation: 68.6 ± 7.8 years; 37 males) who underwent CTA examinations following EVAR. Images were reconstructed using four different methods: hybrid iterative reconstruction (HIR), AiCE, the combination of HIR and SEMAR (HIR + SEMAR), and the combination of AiCE and SEMAR (AiCE + SEMAR). Two radiologists, blinded to the reconstruction techniques, independently evaluated the images. Quantitative assessments included measurements of image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), the longest length of artifacts (AL), and artifact index (AI). These parameters were subsequently compared across different reconstruction methods.
    RESULTS: The subjective results indicated that AiCE + SEMAR performed the best in terms of image quality. The mean image noise intensity was significantly lower in the AiCE + SEMAR group (25.35 ± 6.51 HU) than in the HIR (47.77 ± 8.76 HU), AiCE (42.93 ± 10.61 HU), and HIR + SEMAR (30.34 ± 4.87 HU) groups (p < 0.001). Additionally, AiCE + SEMAR exhibited the highest SNRs and CNRs, as well as the lowest AIs and ALs. Importantly, endoleaks and thrombi were most clearly visualized using AiCE + SEMAR.
    CONCLUSIONS: In comparison to other reconstruction methods, the combination of AiCE + SEMAR demonstrates superior image quality, thereby enhancing the detection capabilities and diagnostic confidence of potential complications such as early minor endleaks and thrombi following EVAR. This improvement in image quality could lead to more accurate diagnoses and better patient outcomes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:探讨心脏选择超分辨率深度学习重建(SR-DLR)在评估支架辅助线圈栓塞患者图像质量中的作用,线圈栓塞,与其他图像重建相比,流动转向支架放置。
    方法:这项单中心回顾性研究包括50名患者(平均年龄,59年;范围,44-81岁;13名男性)接受支架辅助线圈栓塞治疗,线圈栓塞,和2023年1月至7月之间的分流支架放置。使用滤波反投影(FBP)重建图像,混合迭代重建(IR),和SR-DLR。客观图像分析包括Hounsfield单元(HU)中的图像噪声,信噪比(SNR),对比噪声比(CNR),和半高全宽(FWHM)。主观上,两名放射科医生评估了血流转向支架可视化的整体图像质量,线圈,和支架。
    结果:SR-DLR中HU的图像噪声为6.99±1.49,显着低于FBP(12.32±3.01)和混合IR(8.63±2.12)重建的图像(p<0.001)。SR-DLR的平均SNR和CNR均明显高于FBP和混合IR(p<0.001和p<0.001)。支架的FWHM(p<0.004),分流支架(p<0.001),SR-DLR和卷曲(p<0.001)显着低于FBP和混合IR。SR-DLR的主观视觉评分明显高于其他图像重建(p<0.001)。
    结论:SR-DLR与心脏选择是有用的,在支架辅助线圈栓塞和分流支架放置在较低的图像噪声方面的随访成像,更高的SNR和CNR,优越的主观图像分析,与其他图像重建相比,开花伪影更少。
    结论:具有心脏选择的SR-DLR可以更好地显示外周和较小脑动脉。具有心脏选择的SR-DLR可用于支架辅助线圈栓塞和分流支架的CT成像。
    OBJECTIVE: To investigate the usefulness of super-resolution deep learning reconstruction (SR-DLR) with cardiac option in the assessment of image quality in patients with stent-assisted coil embolization, coil embolization, and flow-diverting stent placement compared with other image reconstructions.
    METHODS: This single-centre retrospective study included 50 patients (mean age, 59 years; range, 44-81 years; 13 men) who were treated with stent-assisted coil embolization, coil embolization, and flow-diverting stent placement between January and July 2023. The images were reconstructed using filtered back projection (FBP), hybrid iterative reconstruction (IR), and SR-DLR. The objective image analysis included image noise in the Hounsfield unit (HU), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and full width at half maximum (FWHM). Subjectively, two radiologists evaluated the overall image quality for the visualization of the flow-diverting stent, coil, and stent.
    RESULTS: The image noise in HU in SR-DLR was 6.99 ± 1.49, which was significantly lower than that in images reconstructed with FBP (12.32 ± 3.01) and hybrid IR (8.63 ± 2.12) (P < .001). Both the mean SNR and CNR were significantly higher in SR-DLR than in FBP and hybrid IR (P < .001 and P < .001). The FWHMs for the stent (P < .004), flow-diverting stent (P < .001), and coil (P < .001) were significantly lower in SR-DLR than in FBP and hybrid IR. The subjective visual scores were significantly higher in SR-DLR than in other image reconstructions (P < .001).
    CONCLUSIONS: SR-DLR with cardiac option is useful for follow-up imaging in stent-assisted coil embolization and flow-diverting stent placement in terms of lower image noise, higher SNR and CNR, superior subjective image analysis, and less blooming artifact than other image reconstructions.
    CONCLUSIONS: SR-DLR with cardiac option allows better visualization of the peripheral and smaller cerebral arteries. SR-DLR with cardiac option can be beneficial for CT imaging of stent-assisted coil embolization and flow-diverting stent.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景/目标:为了评估自由呼吸,动态径向磁共振血管造影(MRA),用于在不确定的计算机断层扫描血管造影(CTA)的情况下检测血管内主动脉修复(EVAR)后内漏。方法:这项前瞻性单中心研究包括17名参与者(平均年龄,70±9岁;13名男性)接受动态放射状MRI(金角RAdial稀疏平行体积内插Brath-hold,GRASP-VIBE)在对EVAR治疗的腹主动脉瘤进行随访期间,在不确定的多相CT中是否存在内漏。CT和MRI数据集由两名放射科医生独立评估图像质量。诊断信心,以及内漏的存在/类型。统计分析包括评分者和方法间协议,和诊断性能(灵敏度,特异性,曲线下面积(AUC))。结果:主观图像分析显示两种模式的图像质量和评分者之间的一致性(k≥0.6),而MRA的诊断置信度明显更高(p=0.03)。与CTA(AUC0.66[95%CI:0.41,0.91];p=0.03)相比,MRA(AUC0.97[95%CI:0.87,1.0])检测II型内漏的准确性显着提高。尽管MRA显示出更高的灵敏度值,特异性,AUC,和评估者之间的协议,其他类型和内漏的总体检出率均未显示CT诊断性能的差异(p≥0.12).CTA和MRA在内漏检测中显示出轻度至中度的方法间一致性(k=0.3-0.64)。结论:GRASP-VIBEMRA具有较高的时空分辨率,具有良好的图像质量和较高的诊断置信度,具有临床可行性。它显著增强了检测和分类内漏的诊断性能,特别是II型,与传统的多期CTA相比,结果尚无定论。
    Background/Objectives: To assess free-breathing, dynamic radial magnetic resonance angiography (MRA) for detecting endoleaks post-endovascular aortic repair (EVAR) in cases with inconclusive computed tomography angiography (CTA). Methods: This prospective single-center study included 17 participants (mean age, 70 ± 9 years; 13 males) who underwent dynamic radial MRI (Golden-angle RAdial Sparse Parallel-Volumetric Interpolated BrEath-hold, GRASP-VIBE) after inconclusive multiphasic CT for the presence of endoleaks during the follow-up of EVAR-treated abdominal aortic aneurysms. CT and MRI datasets were independently assessed by two radiologists for image quality, diagnostic confidence, and the presence/type of endoleak. Statistical analyses included interrater and intermethod agreement, and diagnostic performance (sensitivity, specificity, area under the curve (AUC)). Results: Subjective image analysis demonstrated good image quality and interrater agreement (k ≥ 0.6) for both modalities, while diagnostic confidence was significantly higher in MRA (p = 0.03). There was significantly improved accuracy for detecting type II endoleaks on MRA (AUC 0.97 [95% CI: 0.87, 1.0]) compared to CTA (AUC 0.66 [95% CI: 0.41, 0.91]; p = 0.03). Although MRA demonstrated higher values for sensitivity, specificity, AUC, and interrater agreement, none of the other types nor the overall detection rate for endoleaks showed differences in the diagnostic performance over CT (p ≥ 0.12). CTA and MRA revealed slight to moderate intermethod concordance in endoleak detection (k = 0.3-0.64). Conclusions: The GRASP-VIBE MRA characterized by high spatial and temporal resolution demonstrates clinical feasibility with good image quality and superior diagnostic confidence. It notably enhances diagnostic performance in detecting and classifying endoleaks, particularly type II, compared to traditional multiphase CTA with inconclusive findings.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:糖尿病是心血管疾病的独立危险因素。这项研究的目的是确定易损冠状动脉斑块(VCP)的危险因素,与不良心血管事件有关,并确定冠状动脉CT血管造影(CCTA)在2型糖尿病(T2DM)和VCPs患者中的价值。
    方法:回顾性分析98例接受CCTA和血管内超声(IVUS)检查的T2DM患者。根据是否存在VCP对患者进行分组和分析。
    结果:在T2DM患者中,范围内的时间[TIR{血糖水平在目标范围内的时间百分比}](OR=0.93,95%CI=0.89-0.96;P<0.001)和高密度脂蛋白胆固醇(HDL-C)浓度(OR=0.24,95%CI=0.09-0.63;P=0.04)与较低的VCP风险相关,但甘油三酯(TG)浓度与VCP的高风险相关(OR=1.79,95%CI=1.01-3.18;P=0.045)。TIR的接收器操作特性曲线(AUC)下的面积,HDL-C和TG浓度分别为0.76、0.73和0.65。TIR的综合预测AUC,HDL-C和TG浓度为0.83(P<0.05)。CCTA灵敏度,特异性,假阴性,诊断VCP的假阳性率为95.74%,94.12%,4.26%,5.88%,分别。CCTA对VCP的鉴定与IVUS呈正相关(组内相关系数[ICC]=0.90)。
    结论:TIR和HDL-C浓度与T2DM患者VCP风险较低相关,TG浓度与VCP风险较高相关。在临床实践中,TIR,T2DM患者需要特别注意HDL-C和TG。CCTA识别VCP的能力与IVUS结果高度相关。
    BACKGROUND: Diabetes is an independent risk factor for cardiovascular disease. The purpose of this study was to identify the risk factors for vulnerable coronary plaques (VCPs), which are associated with adverse cardiovascular events, and to determine the value of coronary CT angiography (CCTA) in patients with type 2 diabetes mellitus (T2DM) and VCPs.
    METHODS: Ninety-eight T2DM patients who underwent CCTA and intravascular ultrasound (IVUS) were retrospectively included and analyzed. The patients were grouped and analyzed according to the presence or absence of VCPs.
    RESULTS: Among the patients with T2DM, time in range [TIR {the percentage of time blood glucose levels were in the target range}] (OR = 0.93, 95% CI = 0.89-0.96; P < 0.001) and the high-density lipoprotein-cholesterol (HDL-C) concentration (OR = 0.24, 95% CI = 0.09-0.63; P = 0.04) were correlated with a lower risk of VCP, but the triglycerides (TG) concentration was correlated with a higher risk of VCP (OR = 1.79, 95% CI = 1.01-3.18; P = 0.045). The area under the receiver operator characteristic curve (AUC) of TIR, and HDL-C and TG concentrations were 0.76, 0.73, and 0.65, respectively. The combined predicted AUC of TIR, and HDL-C and TG concentrations was 0.83 (P < 0.05). The CCTA sensitivity, specificity, false-negative, and false-positive values for the diagnosis of VCP were 95.74%, 94.12%, 4.26%, and 5.88%, respectively. The identification of VCP by CCTA was positively correlated with IVUS (intraclass correlation coefficient [ICC] = 0.90).
    CONCLUSIONS: The TIR and HDL-C concentration are related with lower risk of VCP and the TG concentration was related with higher risk of VCP in patients with T2DM. In clinical practice, TIR, HDL-C and TG need special attention in patients with T2DM. The ability of CCTA to identify VCP is highly related to IVUS findings.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:用于重建大腿前外侧远端/膝关节区缺损的局部皮瓣选择有限。远端深动脉穿支岛状(PAPI)皮瓣是一种局部筋膜皮螺旋桨型皮瓣,它利用了股深动脉的最远端穿支。这项研究的目的是对股深动脉穿支系统进行基于CT的血管造影分析,并介绍PAPI皮瓣在大腿和膝盖远端肿瘤后缺损治疗中的应用结果。
    方法:对25名健康患者的下肢进行了CT血管造影(平均年龄,57岁;男性占76%),并测量了直径大于1mm的隔膜皮肤穿孔器的数量和位置。回顾了由资深作者进行的一系列涉及前外侧和后膝关节的消融后缺损重建患者。
    结果:CT血管造影显示,股深动脉中隔皮穿支的收集效果良好(平均3.5,范围2至5),最远端穿支位于髌骨上缘3.3cm处。PAPI皮瓣成功用于10例患者(6F;4M;平均年龄60.6岁;范围30至88岁),平均缺损大小为87.5cm2(范围48至150cm2)。手持多普勒用于检测穿孔器。没有遇到皮瓣损失,随访时未发现膝关节功能受限。次要并发症包括血清肿(1)和关节内感染(2)。
    结论:我们得出结论,远端PAPI皮瓣是一种可靠且通用的皮瓣,具有广泛的应用前景。
    Locoregional flap options for reconstructing defects of the anterolateral distal thigh/knee region are limited. The distal profunda artery perforator island (PAPI) flap is a local fasciocutaneous propeller-type flap that utilizes the most distal perforator of the profunda femoris artery. The aim of this study is to conduct a CT-based angiographic analysis of the perforator system of the profunda femoris artery and present outcomes on the application of the PAPI flap in the management of post-oncologic defects of the distal thigh and knee.
    CT angiograms were utilized on the lower limbs of 25 healthy patients (mean age, 57 years; 76% male) and the number and location of septocutaneous perforators with a diameter greater than 1 mm were measured. A case series of patients undergoing reconstruction of post-ablative defects which involved the anterolateral and posterior knee performed by the senior author were reviewed.
    CT angiography demonstrated a robust collection (mean 3.5, range 2 to 5) of septocutaneous perforators from the profunda femoris artery with the most distal perforator located 3.3 cm from the superior patella border. The PAPI flap was successfully used in 10 patients (6F; 4M; mean age 60.6 years; range 30 to 88 years) with a mean defect size of 87.5 cm2 (range 48 to 150 cm2 ). Hand-held Doppler was used to detect the perforator. No flap loss was encountered, and no knee function limitation was noted at follow-up. Minor complications include seroma (1) and intra-articular infection (2).
    We conclude that the distal PAPI flap is a reliable and versatile flap that has potentially wide applications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    临床指南中多次强调评估缺血性卒中(IS)患者侧支状态(CS)的重要性。各种出版物提供定性或半定量的量表,其等级对应于抵押品的不同程度,可视化主要基于CTA图像。然而,关于其评估者间可靠性的信息是有限的。因此,这项研究的目的是调查抵押品评估量表的评估者间的可靠性。研究中使用了158例IS急性期患者的CTA图像。CS的评估由两名专家使用三种方法进行:修改的Tan量表,Miteff量表,和罗森塔尔量表。科恩的卡帕,加权kappa和Krippendorffα被用作可靠性度量。对于修改后的Tan量表以及Miteff和Rosenthal量表,加权kappa值分别为0.72,0.49和0.59.尽管对于改良的Tan量表找到了最佳的一致性度量,量表间无统计学差异.改良的Tan和Rosenthal量表显示了CS对出院时神经功能缺损程度的影响。总之,分析表明,这三个量表的评分者间可靠性中等,但无法区分其中最好的一个。
    The importance of assessing the collateral status (CS) in patients with ischaemic stroke (IS) has repeatedly been emphasised in clinical guidelines. Various publications offer qualitative or semiquantitative scales with gradations corresponding to the different extents of the collaterals, visualised mostly on the basis of CTA images. However, information on their inter-rater reliability is limited. Therefore, the aim of this study is to investigate the inter-rater reliability of the scales for collateral assessment. CTA images of 158 patients in the acute period of IS were used in the study. The assessment of CS was performed by two experts using three methodologies: the modified Tan scale, the Miteff scale, and the Rosenthal scale. Cohen\'s kappa, weighted kappa and Krippendorff\'s alpha were used as reliability measures. For the modified Tan scale and the Miteff and Rosenthal scales, the weighted kappa values were 0.72, 0.49 and 0.59, respectively. Although the best measure of consistency was found for the modified Tan scale, no statistically significant differences were revealed among the scales. The impact of the CS on the degree of neurological deficit at discharge was shown for the modified Tan and Rosenthal scales. In conclusion, the analysis showed a moderate inter-rater reliability of the three scales, but was not able to distinguish the best one among them.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    小脑前下动脉(AICA)的动脉瘤是后循环的罕见病变,治疗它们具有挑战性。我们旨在介绍15例AICA动脉瘤的解剖和形态特征。
    回顾性分析15例AICA动脉瘤的DSA和CT血管造影图像。不同的解剖特征被量化,包括形态学,location,宽度,颈部宽度,长度,瓶颈因素,和纵横比。
    80%的患者是女性。年龄为52.4±9.6(平均±SD)岁。11名患者为吸烟者。十名患者患有囊状动脉瘤,五名患者患有梭形动脉瘤。10例动脉瘤位于近端,在三个肉段的病人中,和远端段的两名患者。15例患者中有10例出现动脉瘤破裂。AICA动脉瘤大小为14.8±18.9mm(平均值±SD)。纵横比为0.92±0.47(平均值±SD),瓶颈因子为1.66±1.65(平均值±SD)。
    AICA动脉瘤是后循环的罕见病变,主要见于女性,主要表现为蛛网膜下腔出血,而且大多都很大。
    UNASSIGNED: The aneurysms of the anterior inferior cerebellar artery (AICA) are rare lesions of the posterior circulation and to treat them is challenging. We aim to present anatomical and morphological characteristics of AICA aneurysms in a series of 15 patients.
    UNASSIGNED: The DSA and CT angiography images of AICA aneurysms in 15 consecutive patients were analyzed retrospectively. Different anatomical characteristics were quantified, including morphology, location, width, neck width, length, bottleneck factor, and aspect ratio.
    UNASSIGNED: Eighty percent of the patients were females. The age was 52.4 ± 9.6 (mean ± SD) years. 11 patients were smokers. Ten patients had a saccular aneurysm and five patients had a fusiform aneurysm. Aneurysm in 10 patients were located in the proximal segment, in three patients in the meatal segment, and in two patients in the distal segment. Ten out of 15 patients presented with a ruptured aneurysm. The size of AICA aneurysms was 14.8 ± 18.9 mm (mean ± SD). The aspect ratio was 0.92 ± 0.47 (mean ± SD) and bottleneck factor was 1.66 ± 1.65 (mean ± SD).
    UNASSIGNED: AICA aneurysms are rare lesions of posterior circulation predominantly found in females, present predominantly with subarachnoid hemorrhage, and are mostly large in size.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:在过去的二十年中,已经观察到使用带有肺血管造影(CTPA)的计算机断层扫描来诊断肺栓塞(PE)的显着增加。我们旨在调查在纽约市的一家大型公立医院中是否充分利用了经过验证的诊断预测工具和D-二聚体。
    方法:我们对接受CTPA治疗的患者进行了回顾性分析,以确定在一年内排除PE的具体指征。两名独立审稿人,对彼此以及CTPA和D-二聚体结果不知情,使用Well's评分估计PE的临床概率(CP),YEARS算法,和修改后的日内瓦分数。根据CTPA中是否存在PE对患者进行分类。
    结果:共有917名患者被纳入分析(中位年龄:57岁,女性:59%)。563名独立评审员认为PE的临床概率较低(61.4%),487(55%),184名(20.1%)患者,YEARS算法,和修改后的日内瓦分数,分别。在不到一半的患者中进行了D-二聚体测试,这些患者被认为是由两个独立的审阅者认为具有低CP的PE。在低CP的PE患者中使用<500ng/mL的D-二聚体截止值或年龄调整的截止值将仅错过少数主要是亚段PE。这三个工具,当与D-二聚体<500ng/mL或<年龄调整的截止值联合使用时,NPV>95%。
    结论:当结合D-二聚体截止值<500ng/mL或年龄调整后的截止值时,发现所有三种有效的诊断预测工具在排除PE方面具有显著的诊断价值。CTPA的过度使用可能是次要的诊断预测工具的次优使用。
    BACKGROUND: A significant increase in the use of computed tomography with pulmonary angiography (CTPA) for the diagnosis of pulmonary embolism (PE) has been observed in the past twenty years. We aimed to investigate whether the validated diagnostic predictive tools and D-dimers were adequately utilized in a large public hospital in New York City.
    METHODS: We conducted a retrospective review of patients who underwent CTPA for the specific indication of ruling out PE over a period of one year. Two independent reviewers, blinded to each other and to the CTPA and D-dimer results, estimated the clinical probability (CP) of PE using Well\'s score, the YEARS algorithm, and the revised Geneva score. Patients were classified based on the presence or absence of PE in the CTPA.
    RESULTS: A total of 917 patients were included in the analysis (median age: 57 years, female: 59%). The clinical probability of PE was considered low by both independent reviewers in 563 (61.4%), 487 (55%), and 184 (20.1%) patients based on Well\'s score, the YEARS algorithm, and the revised Geneva score, respectively. D-dimer testing was conducted in less than half of the patients who were deemed to have low CP for PE by both independent reviewers. Using a D-dimer cut-off of <500 ng/mL or the age-adjusted cut-off in patients with a low CP of PE would have missed only a small number of mainly subsegmental PE. All three tools, when combined with D-dimer < 500 ng/mL or 95%.
    CONCLUSIONS: All three validated diagnostic predictive tools were found to have significant diagnostic value in ruling out PE when combined with a D-dimer cut-off of <500 ng/mL or the age-adjusted cut-off. Excessive use of CTPA was likely secondary to suboptimal use of diagnostic predictive tools.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Review
    主动脉上动脉的计算机断层扫描血管造影(CTA)通常用于急性中风检查,并可能显示心尖肺病变(APL)。
    要确定患病率,后续算法,以及CTA上有APL的卒中患者的院内结局。
    我们回顾性纳入了连续成年缺血性卒中患者,短暂性脑缺血发作,或脑出血,并在2014年1月至2021年5月期间在三级医院获得CTA。我们回顾了所有CTA报告中是否存在APL。根据放射学形态学标准,APL被分类为恶性可疑或良性出现。我们进行了回归分析,以调查恶性可疑APL对不同院内结局参数的影响。
    在2715名患者中,在161例患者中发现CTA上的APL(5.9%[95CI:5.1-6.9];161/2715)。1/3的APL患者存在恶性肿瘤的嫌疑(36.0%[95CI:29.0-43.7];58/161),其中42人(72.4%[95CI:60.0-82.2];42/58)无肺癌或转移史。执行时,进一步调查证实了四分之三的原发性或继发性肺部恶性肿瘤(75.0%[95CI:50.5-89.8];12/16),2例患者(16.7%[95CI:4.7-44.8];2/12)接受从头肿瘤治疗。在多变量回归中,放射学恶性可疑APL的存在与24h较高的NIHSS评分(β=0.67,95CI:0.28~1.06,p=0.001)和全因住院死亡率(aOR=3.83,95CI:1.29~9.94,p=0.01)相关.
    十七个患者中有一个在CTA上显示APL,其中三分之一是可疑的恶性肿瘤。进一步的检查证实了大量患者的肺部恶性肿瘤,触发了潜在的挽救生命的肿瘤治疗。
    Computed tomography angiography (CTA) of the supraaortic arteries is commonly used for acute stroke workup and may reveal apical pulmonary lesions (APL).
    To determine the prevalence, follow-up algorithms, and in-hospital outcomes of stroke patients with APL on CTA.
    We retrospectively included consecutive adult patients with ischemic stroke, transient ischemic attack, or intracerebral hemorrhage and available CTA at a tertiary hospital between January 2014 and May 2021. We reviewed all CTA reports for the presence of APL. APL were classified as malignancy suspicious or benign appearing based on radiological-morphological criteria. We performed regression analyses to investigate the impact of malignancy suspicious APL on different in-hospital outcome parameters.
    Among 2715 patients, APL on CTA were found in 161 patients (5.9% [95%CI: 5.1-6.9]; 161/2715). Suspicion of malignancy was present in one third of patients with APL (36.0% [95%CI: 29.0-43.7]; 58/161), 42 of whom (72.4% [95%CI: 60.0-82.2]; 42/58) had no history of lung cancer or metastases. When performed, further investigations confirmed primary or secondary pulmonary malignancy in three-quarters (75.0% [95%CI: 50.5-89.8]; 12/16), with two patients (16.7% [95%CI: 4.7-44.8]; 2/12) receiving de novo oncologic therapy. In multivariable regression, the presence of radiologically malignancy suspicious APL was associated with higher NIHSS scores at 24 h (beta = 0.67, 95%CI: 0.28-1.06, p = 0.001) and all-cause in-hospital mortality (aOR = 3.83, 95%CI: 1.29-9.94, p = 0.01).
    One in seventeen patients shows APL on CTA, of which one-third is malignancy suspicious. Further work-up confirmed pulmonary malignancy in a substantial number of patients triggering potentially life-saving oncologic therapy.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号