目的:描述和评估角膜结膜转位术(CTT)作为犬深部间质溃疡的外科治疗方法,次生孢子,和全层角膜缺损,并确定其在保持角膜移植物透明度和视力方面的功效。
方法:一百只患有深层间质溃疡的客户拥有的狗,次生孢子,或全厚度角膜缺陷。
方法:接受CCT的犬科患者的医疗记录,从2012年到2018年,进行了回顾。只有,包括术前合意瞳孔光和眩光反射阳性的患者。
结果:男性59例,女性41例,从0.3到17年。短脑品种的比例过高(65%)。所有患者均为单侧受累,有16个深层间质溃疡,33次生孢子,51个角膜穿孔,中值(范围)尺寸为4(2-8)mm。在大多数情况下(57%)中央角膜受到影响,眼眶和干燥性角膜结膜炎是最常见的并发眼病(42%和40%,分别)。移植物最常从背侧收获(67%),使用9/0可吸收缝合材料。术中、术后并发症7例,21例,分别。平均随访时间为107.8天。96%的患者视力得以保留,62%的人表现出微弱到轻度的混浊。在统计分析的变量中,发现眼睑和色素性角膜炎与较大的角膜移植物混浊显着相关(分别为P=.040和P=.028)。
结论:角膜结膜转位是治疗深部间质瘤的有效手术方法,后代囊肿,和狗的全层角膜缺陷,实现高度令人满意的角膜移植物透明度和保持视力。
OBJECTIVE: To describe and evaluate the use of corneoconjunctival transposition (CTT) as a surgical treatment for canine deep stromal ulcers, descemetoceles, and full-thickness corneal defects and to determine its efficacy in preserving corneal graft transparency and vision.
METHODS: One hundred client-owned dogs with deep stromal ulcers, descemetoceles, or full-thickness corneal defects.
METHODS: Medical records of canine patients that underwent CCT, from 2012 to 2018, were reviewed. Only, patients with preoperative positive consensual pupillary light and dazzle reflexes were included.
RESULTS: There were 59 males and 41 females, from 0.3 to 17 years. Brachycephalic breeds were overrepresented (65%). All patients were unilaterally affected, with 16 deep stromal ulcers, 33 descemetoceles, and 51 corneal perforations, of a median (range) size of 4 (2-8) mm. The central cornea was affected in the majority of cases (57%), and euryblepharon and keratoconjunctivitis sicca were the most common concurrent ocular diseases (42% and 40%, respectively). The graft was most frequently harvested from dorsal (67%), and 9/0 absorbable suture material was used. Intraoperative and postoperative complications were seen in 7 and 21 cases, respectively. Mean follow-up time was 107.8 days. Vision was preserved in 96% patients, with 62% showing faint to mild opacification. Among the statistically analyzed variables, euryblepharon and pigmentary keratitis were found to be significantly associated with greater corneal graft opacification (P = .040 and P = .028, respectively).
CONCLUSIONS: Corneoconjunctival transposition is an effective surgical treatment for deep stromal, descemetocele, and full-thickness corneal defects in dogs, achieving a highly satisfactory degree of corneal graft transparency and preserving vision.