非愈合性溃疡对临床医生显示出值得注意的示范性挑战。虽然通常归因于感染等常见原因,这些持续的伤口偶尔会掩盖更险恶的潜在疾病:恶性肿瘤。该病例报告介绍了一名39岁的印度男子,其右臀区溃疡未愈合。尽管对假定的细菌感染进行了初步治疗,溃疡持续存在。活检最终发现一个可能是造血来源的恶性肿瘤,CD30阳性和CD45局灶性阳性。进一步调查,包括核磁共振,FNAC,还有X光片,提示淋巴瘤。由于病因不同,非愈合性溃疡面临挑战。彻底了解潜在的原因,包括传染性,血管,自身免疫,和恶性病因,对于导航诊断过程至关重要。该病例强调了维持非愈合性溃疡的广泛鉴别诊断的关键作用以及活检在明确诊断中的重要性。在这种情况下,早期识别恶性肿瘤对于最佳的患者管理至关重要。该病例强调了在患有持续性溃疡的患者中考虑恶性肿瘤并进行活检以进行明确诊断的重要性。虽然最初的演讲模仿了一个感染过程,活检显示可能为皮肤间变性T细胞淋巴瘤.需要进一步的研究来明确分类特定的淋巴瘤亚型并指导进一步的治疗决策。
Non-healing ulcers display a noteworthy demonstrative challenge for clinicians. While often attributed to common causes like infections, these persistent wounds can occasionally mask a more sinister underlying condition: malignancy. This
case report presents a 39-year-old Indian man with a non-healing ulcer on his right gluteal region. Despite initial treatments for a presumed bacterial infection, the ulcer persisted. Biopsy ultimately revealed a malignant neoplasm of possible hematopoietic origin, positive for CD30 and focally positive for CD45. Further investigations, including MRI, FNAC, and X-rays, were indicative of lymphoma. Non-healing ulcers present a challenge due to diverse etiologies. A thorough understanding of potential causes, including infectious, vascular, autoimmune, and malignant etiologies, is crucial for navigating the diagnostic process. This
case highlights the critical role of maintaining a broad differential diagnosis for non-healing ulcers and the importance of a biopsy in reaching a definitive diagnosis. Early recognition of malignancy in such cases is essential for optimal patient management. This
case underscores the importance of considering malignancy in patients with persistent ulcers and performing biopsies for a definitive diagnosis. While the initial presentation mimicked an infectious process, the biopsy revealed a possible cutaneous anaplastic T-cell lymphoma. Further investigations are necessary to definitively classify the specific lymphoma subtype and guide further treatment decisions.