乳腺多发性骨髓瘤(MM)很少被记录。然而,没有关于胸壁软组织和乳房肿块作为MM的主要症状的报告。在这里,我们报告了一例68岁女性,她的右乳房和胸壁有肿块,持续1个月。她回忆起患有干眼症和口干症2年,没有进行任何测试来寻找这些症状的原因。超声检查(US)和计算机断层扫描(CT)检查显示右侧乳房和胸壁有肿块。超声引导下穿刺活检证实乳腺和胸壁病灶均为浆细胞瘤,骨髓检查证实为MM。同时,干燥综合征(SS)通过抗核抗体的阳性表达诊断,Ro/SSA和La/SSB。经过三个疗程的MM化疗后,SS症状明显减轻,胸壁和乳房肿块消失。
Multiple myeloma (MM) in the breast has been rarely documented. However, there are no
reports on concurrent masses of chest wall soft tissue and breast as the primary symptoms for MM. Herein, we report a
case of a 68-year-old woman presented with masses in her right breast and chest wall for 1 month. She recalled having xerophthalmia and xerostomia for 2 years without taking any test to search for the cause of these symptoms. Ultrasonography (US) and computed tomography (CT) examination revealed masses in the right breast and chest wall. Both lesions of the breast and chest wall were confirmed to be plasma cell tumors by ultrasound-guided puncture biopsy and MM was confirmed by bone marrow examination. Meanwhile, Sjogren\'s syndrome (SS) was diagnosed by the positive expression of antibodies against antinuclear, Ro/SSA and La/SSB. After three courses of chemotherapy for MM, the symptoms of SS were significantly alleviated and the masses in the chest wall and breast disappeared.