■为了改进鼻内皮质类固醇(INC)给药的(患者定制)说明,我们需要深入了解INC用户的具体特征和奉献使用。
■我们检查了从荷兰互动数据库获得的INC处方,以了解患病率和发病率,INC在前几年的使用,和奉献。
■我们回顾性检查了2015年1月1日至2019年12月31日之间开出的INC处方。患病率和发病率按年龄和性别分层。分析了前几年INCs的使用情况和自白情况。
■2019年,共开出172,563张INC处方,并发放给75,048人。同样在2019年,INC用户的患病率和发病率分别为68.9和25.6/1000个人,分别。所有年龄组均使用INCs。2019年,超过一半的INC用户在2018年没有收到处方,近四分之一的用户连续5年收到处方。28%的人将INC与吸入器结合使用,29%的人使用INC和全身性抗组胺药,9%的人使用INC和眼部药物,1%的人使用了鼻内抗组胺药。2%至16%的研究人员将几种含皮质类固醇的药物与INCs联合使用。
■这项研究为患者量身定制的指导提供了见解。INC被不同年龄组和新的或间歇性的用户以及连续的用户使用。在这些结果的基础上,可以制定针对患者量身定制的说明书,随后进行研究,以确定这些说明书是否会影响治疗依从性和疗效.有关奉献的见解为改进INC管理技术的评估提供了机会。一起来看,这些建议可能会导致更适合患者的方法,这可能反过来导致改善INCs的治疗。
UNASSIGNED: To improve (patient-tailored) instructions for intranasal corticosteroid (INC) administration, we need to gain insight into specific
characteristics of INC users and comedication use.
UNASSIGNED: We examined INC prescriptions obtained from the Dutch InterAction Database to gain insight into the prevalence and incidence rates, INC use in previous years, and comedication.
UNASSIGNED: We retrospectively examined INC prescriptions written between January 1, 2015, and December 31, 2019. Prevalence and incidence rates were stratified by age and sex. The use of INCs in previous years and comedication were analyzed.
UNASSIGNED: In 2019, a total of 172,563 INC prescriptions were written and dispensed to 75,048 individuals. Also in 2019, the prevalence and incidence of INC users were 68.9 and 25.6 per 1000 individuals, respectively. INCs were used by all age groups. More than half of INC users in 2019 did not receive a prescription in 2018, almost a quarter received a prescription in 5 consecutive years, 28% used an INC in combination with an inhaler, 29% used an INC together with a systemic antihistamine, 9% used an INC along with ocular medication, and 1% used an INC with an intranasal antihistamine. Several corticosteroid-containing drugs were being used in combination with INCs by 2% to 16% of those studied.
UNASSIGNED: This study gives insights into opportunities for patient-tailored instructions. INCs are used by various age groups and by new or intermittent users as well as by continuous users. On the bases of these results, patient-tailored instructions can be developed and subsequently studied to determine whether the instructions affect treatment adherence and efficacy. The insights gained about comedication provide opportunities for improved evaluation of the INC administration technique. Taken together, these suggestions might lead to a more patient-tailored approach, which might in turn lead to improved treatment with INCs.