目的:评估原发性后连续曲线撕囊(PPCCC)对IOL位置稳定性的影响。
方法:本研究是一项前瞻性个体内比较随机对照试验,包括31名患者(62只眼)。将同一患者的眼睛随机分配到PPCCC组(18只右眼和13只左眼)或无PPCCC组(NPCCC组)。通过常规白内障手术,两组的眼睛均植入了一件式可折叠的疏水丙烯酸IOL。PPCCC组的患者在IOL植入前接受了额外的手动PPCCC。检查进行了1天,1周,术后1个月和3个月。IOL倾斜(x,y),分散(x,y),收集前房深度(z)和屈光预测误差数据,并用Pentacam进行分析.
结果:术后,PPCCC组3个月内IOL位置变化范围与NPCCC组相当,这表明每个倾斜和偏心指数的值较小。在本研究终点中,PPCCC眼睛与NPCCC眼睛表现出可比的倾斜和偏心:平均倾斜(x,y),分散(x,y)和前房深度(ACD)为1.04±0.56°,0.90±0.64°,0.239±0.140mm,0.233±0.133mm和4.01±0.32mm,分别,在PPCCC组vs.1.09±0.76°,1.10±0.82°,0.252±0.153mm,0.244±0.155mm和4.01±0.38mm,分别,在NPCCC组中。PPCCC组的屈光预测误差表现为轻度远视移位与NPCCC组(0.13±0.50vs.0.05±0.39;p=0.208),和矫正视力(CDVA)在两组之间没有差异(0.027±0.014vs.0.059±0.185;p=0.377)。
结论:可比较的IOL倾斜,权力下放,在接受常规白内障手术的PPCCC眼中观察到ACD和屈光预测误差。随着时间的推移,PPCCC组IOL位置波动小,视力良好。
背景:该研究于5月27日在中国临床试验注册中心注册,2020年(协议代码ChiCTR2000033304,2020年5月27日)。
OBJECTIVE: To evaluate the effect of primary posterior continuous curvilinear capsulorrhexis (PPCCC) on the positional stability of IOLs.
METHODS: This
study is a prospective intra-individual comparative randomized controlled
trial including 31 patients (62 eyes). Eyes of the same patient were randomly assigned to the PPCCC group (18 right eyes and 13 left eyes) or group without PPCCC (NPCCC group). Eyes in both groups were implanted with a one-piece foldable hydrophobic acrylic IOL via routine cataract surgery. Patients in the PPCCC group underwent additional manual PPCCC before IOL implantation. Examinations were performed 1 day, 1 week, 1 month and 3 months postoperatively. IOL tilt (x, y), decentration (x, y), anterior chamber depth (z) and refractive prediction error data were collected and analyzed with Pentacam.
RESULTS: Postoperatively, the range of IOL position change over 3 months in PPCCC group was comparable to NPCCC group, which indicated smaller value in every tilt and decentration index. PPCCC eyes showed comparable tilt and decentration with NPCCC eyes in this
study endpoint: mean tilt (x, y), decentration (x, y) and anterior chamber depth (ACD) were 1.04 ± 0.56°, 0.90 ± 0.64°, 0.239 ± 0.140 mm, 0.233 ± 0.133 mm and 4.01 ± 0.32 mm, respectively, in the PPCCC group vs. 1.09 ± 0.76°, 1.10 ± 0.82°, 0.252 ± 0.153 mm, 0.244 ± 0.155 mm and 4.01 ± 0.38 mm, respectively, in the NPCCC group. Refractive prediction error in the PPCCC group demonstrated a mild hyperopic shift vs. the NPCCC group (0.13 ± 0.50 vs. 0.05 ± 0.39; p = 0.208), and corrected distance visual acuity (CDVA) did not differ between the two groups (0.027 ± 0.014 vs. 0.059 ± 0.185; p = 0.377).
CONCLUSIONS: Comparable IOL tilt, decentration, ACD and refractive prediction error were observed in PPCCC eyes with that underwent routine cataract surgery. Little IOL position fluctuation and good visual acuity were shown in PPCCC group over time.
BACKGROUND: The
study was registered at the Chinese Clinical
Trial Register Center on May 27th, 2020 (protocol code ChiCTR2000033304, 27/05/2020).