bone lesion

骨病变
  • 文章类型: Case Reports
    在胸壁上发展的肿瘤通常很少见。此病例报告强调了罕见的源自第四肋骨前弓的巨细胞瘤。病人,一个21岁的男性,呈现一个膨胀的质量,在八个月的时间里逐渐增加,达到12x8厘米的尺寸。尽管有明显的肿胀,患者报告无相关疼痛或不适,否认有任何体重减轻或外伤史.没有胸痛或心血管症状将这种情况与其他胸壁病变区分开。该报告强调了在胸壁肿块的鉴别诊断中考虑罕见实体如巨细胞瘤的重要性。尤其是在临床表现和患者病史与更常见的情况不一致的情况下。
    Tumors that develop on the chest wall are usually rare. This case report highlights a rare occurrence of a giant cell tumor originating from the anterior arch of the fourth rib. The patient, a 21-year-old male, presented with a bulging mass that had been gradually increasing in size over an eight-month period, reaching dimensions of 12 x 8 cm. Despite the noticeable swelling, the patient reported no associated pain or discomfort and denied any history of weight loss or trauma. The absence of chest pain or cardiovascular symptoms distinguished this case from other chest wall pathologies. This report underscores the importance of considering rare entities such as giant cell tumors in the differential diagnosis of chest wall masses, especially in cases where clinical presentation and patient history do not align with more common conditions.
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  • 文章类型: Case Reports
    朗格汉斯细胞组织细胞增生症(LCH)是一种罕见的疾病,治疗选择有限。我们介绍了一例涉及一名57岁妇女的病例,该妇女患有孤立的LCH骨溶骨性病变。单次输注双膦酸盐可显着缓解疼痛,通过CT进行后续扫描,PET-CT,MRI显示病灶实质上重新钙化。进行广泛的文献综述,我们确定了46例记录双膦酸盐在LCH中的疗效的病例.这些发现引起了人们对双膦酸盐输注作为类似情况下的简单治疗替代方案的兴趣,对LCH患者的骨再钙化和疼痛控制有好处。
    Langerhans cell histiocytosis (LCH) is a rare disease with limited treatment options. We present a case involving a 57-year-old woman afflicted with an isolated LCH bone osteolytic lesion. A single bisphosphonate infusion significantly alleviated pain, and follow-up scans via CT, PET-CT, and MRI revealed a substantial recalcification of the lesion. Conducting an extensive literature review, we identified 46 cases documenting the efficacy of bisphosphonates in the context of LCH. These findings have raised interest in bisphosphonate infusion as a simple therapeutic alternative in similar situations, with benefits in terms of bone recalcification and pain control for individuals with LCH.
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  • 文章类型: Case Reports
    坏死性外耳炎(NOE)是一种罕见的侵袭性感染,影响EAC和颅底。这种情况在老年人中更为普遍,糖尿病患者,和免疫受损的个体,通常归因于铜绿假单胞菌。在这个案例报告中,我们介绍了一名有糖尿病和癫痫病史的90岁女性的临床情况.最初因急性肾盂肾炎入院,发烧,和虚脱,她随后在治疗期间出现左面瘫。颅骨计算机断层扫描(CT)显示中耳发炎,面神经管骨侵蚀。耳部的检查,鼻子,喉部(ENT)描述NOE是最可能的诊断。鉴于患者的合并症和疾病的严重程度,该治疗是根据经验开始的,随后根据头孢他啶的培养和敏感性结果进行调整.由于相关的并发症风险,NOE是需要早期诊断和跨学科合作的危急情况。充足的血糖控制势在必行,鉴于耐药性不断升级,明智使用抗生素至关重要。
    Necrotizing otitis externa (NOE) is a rare invasive infection affecting the EAC and the base of the skull. This condition is more prevalent in the elderly, diabetics, and immunocompromised individuals, often attributed to the bacterium Pseudomonas aeruginosa. In this case report, we present the clinical scenario of a 90-year-old woman with a history of diabetes and epilepsy. Initially admitted with acute pyelonephritis, fever, and prostration, she subsequently developed left facial paralysis during treatment. Cranial computed tomography (CT) revealed inflammation in the middle ear and bone erosion of the facial nerve canal. The examination by the Department of Ear, Nose, and Throat (ENT) describes that NOE would be the most likely diagnosis. Given the patient\'s comorbidities and the severity of the disease, the treatment was initiated empirically and later adjusted based on the culture and sensitivity results with ceftazidime. NOE is a critical condition requiring early diagnosis and interdisciplinary collaboration due to the associated risk of complications. Adequate glycemic control is imperative, and the judicious use of antibiotics is crucial in light of escalating resistance.
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  • 文章类型: Case Reports
    纤维发育不良是一种罕见的良性骨疾病,其特征是用成纤维细胞和成骨细胞代替正常骨。我们介绍了一名25岁男性患者的单骨纤维发育不良病例。该病例突出了临床表现,射线照相特征,以及针对这种情况的管理方法。本报告旨在帮助理解纤维发育不良及其管理方案。一名25岁的男性表现为持续的左髋部疼痛。疼痛被描述为隐痛,与负重活动困难有关。没有外伤史或全身症状。体格检查显示左下肢外旋。由于疼痛,无法评估左髋关节的活动范围,没有发现神经功能缺损.初始成像包括右股骨的平片,表现出放射状病变,具有毛玻璃外观和皮质变薄。两个髋关节的磁共振成像显示涉及左股骨颈的不规则T2高强度和T1低信号病变;此外,病变内很少见微小的囊性间隙。部分病变延伸至股骨头上外侧,周围骨髓水肿,左髋关节积液最少,提示原发性骨肿瘤的特征。髋关节和骨盆的普通计算机断层扫描(CT)提示扩张性溶解性病变,其中骨间隔薄,左股骨头硬化边缘厚,大转子伴股骨颈下骨折,提示骨肿瘤(?巨细胞瘤>单纯性骨囊肿)。进行了骨活检,组织病理学检查证实了纤维发育不良的诊断,具有特征性的编织骨和纤维基质。在这种情况下,确诊后,患者接受左侧全髋关节置换术治疗.单骨纤维发育不良是一种罕见的良性骨疾病,可表现为各种临床表现。及时诊断,通过结合临床,射线照相,组织病理学评估至关重要。管理应根据患者的症状进行调整。
    Fibrous dysplasia is a rare benign bone disorder characterized by the replacement of normal bone with fibroblastic and osteoblastic tissue. We present a case of monostotic fibrous dysplasia in a 25-year-old male patient. The case highlights the clinical presentation, radiographic features, and management approach for this condition. This report aims to contribute to the understanding of fibrous dysplasia and its management options. A 25-year-old male presented with a chief complaint of persistent left hip pain. The pain was described as a dull ache, associated with difficulty in weight-bearing activities. There was no history of trauma or constitutional symptoms. Physical examination revealed externally rotated left lower limb. Range of motion of the left hip could not be assessed due to pain, with no neurological deficits noted. Initial imaging included plain radiographs of the right femur, which demonstrated a radiolucent lesion with a ground-glass appearance and cortical thinning. Magnetic resonance imaging of both hip joints reveals an irregular T2 hyperintense and T1 hypointense lesion involving the left femoral neck; moreover, few tiny cystic spaces are seen within the lesion. Part of the lesion is extending into the superior-lateral aspect of the femoral head and surrounding bone marrow edema with minimal left hip joint effusion, features suggestive of a primary bony tumour. Plain computed tomography (CT) of the hip joint and pelvis was suggestive of an expansile lytic lesion with thin bony septation within and thick sclerotic margin in the left femoral head and greater trochanter associated with sub-capital femoral neck fracture suggestive of bone neoplasm (? giant cell tumour > simple bone cyst). A bone biopsy was performed, and histopathological examination confirmed the diagnosis of fibrous dysplasia, with characteristic woven bone and fibrous stroma. In this case, after confirming the diagnosis, the patient was managed with total hip arthroplasty on the left side. Monostotic fibrous dysplasia is a rare benign bone disorder that can present with various clinical manifestations. Timely diagnosis through a combination of clinical, radiographic, and histopathological assessments is crucial. Management should be tailored to the patient\'s symptoms.
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  • 文章类型: Case Reports
    动脉瘤性骨囊肿(ABCs)是良性的,由多个充血腔组成的非肿瘤性囊性病变,它们被结缔组织间隔隔开,它们占所有颅骨和颌骨病变病例的约6%和1.5%,分别。
    这里,介绍了一例80岁男性,经组织学证实诊断为ABC,涉及左下颌骨。患者在使用矫形器造影术确认诊断后接受了部分颌骨切除术,计算机断层扫描,还有组织活检.随访1年后患者无疼痛,对照体位造影显示无复发迹象.随后用钛板和左股骨外侧三分之二的一块骨头重建了骨的愈合部分,此后他的美容状况良好。
    ABCs患者存在扩张性和放射性骨病变,这可能与牙槽骨侵蚀引起的牙齿移位和脱落有关。为了预防复发和发病率增加,必须完全切除病变。
    涉及颌骨的ABCs极为罕见,并且更有可能构成诊断挑战,因为它们在临床上更有可能与其他扩张性放射性骨病变(如成釉细胞瘤)混淆。成骨细胞瘤,和巨细胞瘤等等。此外,大量骨基质形成的患者有时会在组织学上与包括骨肉瘤在内的其他骨形成肿瘤相混淆。复发是常见的,但可以通过完全切除病变来避免或减少复发。
    UNASSIGNED: Aneurysmal bone cysts (ABCs) are benign, non-neoplastic cystic lesions composed of multiple blood-filled cavities, which are separated by connective tissue septa and they constitute ~6 and 1.5% of all cases of the skull and jaws lesions, respectively.
    UNASSIGNED: Herein, the case of an 80-year-old male with a histologically confirmed diagnosis of ABC involving the body of the left mandible was presented. The patient underwent partial mandiblectomy after confirmation of the diagnosis using orthopantomography, a computed tomography scan, and a tissue biopsy. The patient was free from pain after 1-year of follow-up, and the control orthopantomography showed no evidence of recurrence. This was followed by reconstruction of the healed part of the bone with titanium plates and a piece of bone from the lateral two-thirds of the left femur and thereafter he was cosmetically well.
    UNASSIGNED: Patients with ABCs present with expansile and radiolucent bone lesions, which may be associated with displacement and loss of teeth due to alveolar bone erosion. Complete excision of the lesions is mandatory for the prevention of recurrence and increased morbidity.
    UNASSIGNED: ABCs that involve the jaws are extremely rare and are more likely to pose a diagnostic challenge as they are more likely to be confused clinically with other expansile radiolucent bone lesions such as ameloblastoma, osteoblastoma, and giant cell tumor among many others. Also, those with extensive bone matrix formation may sometimes be confused histologically with other bone forming tumors including osteosarcoma. Recurrence is common but it can be avoided or minimized by complete resection of the lesion.
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  • 文章类型: Case Reports
    假性动脉瘤是血管壁损伤后发生的血管病变。周围动脉假性动脉瘤作为骨折并发症并不常见,通常在创伤或手术后立即出现。我们报告了一个独特的病例,与骨盆创伤后20年的髂外动脉假性动脉瘤相关的坐骨神经麻痹,在骨折部位表现为糜烂性骨病变,伪装成可能的恶性肿瘤。据我们所知,没有报告涉及坐骨神经疼痛的髂外动脉假性动脉瘤的病例。
    我们介绍了一位78岁的女性,她的髋臼骨折后恢复了20年。患者出现伤后症状和体格检查结果与坐骨神经麻痹一致。计算机断层扫描血管造影和双重成像显示髂外动脉假性动脉瘤。患者被带到手术室,使用覆膜支架对髂外动脉进行血管内修复。
    这种坐骨神经麻痹是对有关观察到的特定血管损伤和导致坐骨神经麻痹的假性动脉瘤延迟表现的文献的独特贡献。面对可疑的骨盆肿块时,整形外科医生必须考虑很大的差异。如果外科医生尝试进行开放式清创术或采样,则无法将其诊断为血管病因可能是灾难性的。
    UNASSIGNED: Pseudoaneurysms are vascular lesions occurring after injury to a blood vessel wall. Peripheral artery pseudoaneurysms as a fracture complication are uncommon and typically appear immediately after trauma or surgery. We report a unique case of sciatic nerve palsy associated with external iliac artery pseudoaneurysm arising 20 years after pelvic trauma, presenting within the fracture site as an erosive bone lesion masquerading as a possible malignancy. To the best of our knowledge, no cases of delayed external iliac artery pseudoaneurysm involving sciatic pain have been reported.
    UNASSIGNED: We present a 78-year-old female who sustained an acetabular fracture with an uneventful recovery for 20 years. The patient presented post-injury with symptoms and physical examination findings consistent with sciatic nerve palsy. Computed tomography angiography and duplex imaging revealed a pseudoaneurysm of the external iliac artery. The patient was taken to the operating room for endovascular repair of the external iliac artery using a covered stent.
    UNASSIGNED: This case of sciatic nerve palsy is a unique contribution to the literature concerning the specific vascular injury observed and the delayed presentation of pseudoaneurysm causing sciatic nerve palsy. Orthopedic surgeons must consider a wide differential when confronted with suspicious pelvic masses. Failure to diagnose these as a vascular etiology could prove catastrophic should the surgeon attempt an open debridement or sampling.
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  • 文章类型: Case Reports
    假体周围骨质溶解(PPOL)是全髋关节置换术后的严重并发症,需要立即采取行动以防止进一步扩散到附近组织,并有机会成功恢复髋关节功能。我们介绍了具有挑战性治疗过程的患者的PPOL病例。
    我们报告了一名75岁的PPOL患者,该患者在初次全髋关节置换术14年后扩散到软组织和骨盆区域。在治疗的各个阶段,在未检测微生物培养的左髋关节滑液抽吸分析中,检测到中性粒细胞优势细胞计数升高.由于严重的骨质流失和一般的患者状况,没有进一步的手术治疗,对未来的行动没有明确的愿景。
    严重PPOL的管理可能具有挑战性,由于手术治疗选择有限,长期预后良好。如果怀疑是溶骨过程,应尽快治疗,以避免更严重的并发症进展。
    UNASSIGNED: Periprosthetic osteolysis (PPOL) is a serious complication after total hip replacement and requires immediate action to prevent further spread to nearby tissues and has the opportunity to restore hip function successfully. We present the case of PPOL of a patient with a challenging course of treatment.
    UNASSIGNED: We report a 75-year-old patient with PPOL that spreads to the soft tissues and pelvic region 14 years after primary total hip arthroplasty. At all stages of treatment, an elevated neutrophil-dominant cell count was detected in the analysis of synovial fluid aspiration of the left hip joint without detection of microbiological culture. Due to severe bone loss and general patient condition, no further surgical treatment was indicated, and there is no clear vision of future actions.
    UNASSIGNED: Management of severe PPOL can be challenging, as there are limited surgical treatment options with a good long-term prognosis. If an osteolytic process is suspected, it should be treated as soon as possible to avoid more severe progression of the complications.
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  • 文章类型: Case Reports
    一名60岁的女性桡骨远端骨折,并用掌侧锁定钢板进行了切开复位内固定。患者恢复顺利,直到术后四个月,当患者临床消退时,和一种扩张性,发现放射性不透的骨phy骨损害。进一步的检查显示这是骨巨细胞瘤(GCTB)。明确的管理包括广泛的刮宫,冷冻消融,和病变的骨水泥,硬件完好无损。当前病例表现为GCTB的罕见表现。该案例说明了在临床改善平稳或消退时彻底检查术后X光片的重要性,以及在临床过程不典型时需要进行额外的检查。作者质疑GCTB的亚放射学表现的可能性。
    A 60-year-old female sustained a distal radius fracture and underwent open reduction internal fixation with a volar locking plate. The patient had an uneventful recovery until four months postoperatively when the patient clinically regressed, and an expansile, radiolucent metaepiphyseal lesion was found. Further workup revealed this was a giant cell tumor of bone (GCTB). Definitive management consisted of extensive curettage, cryoablation, and cementation of the lesion, and the hardware was left intact. The current case presents an uncommon presentation of GCTB. The case illuminates the importance of thorough scrutiny of postoperative radiographs when clinical improvement plateaus or regresses and the need to pursue additional workup when the clinical course is atypical. The authors query the possibility of a sub-radiological presentation of GCTB.
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  • 文章类型: Case Reports
    在骨科创伤实践中,小儿胫骨和腓骨远端骨折很常见。大多数患者通过闭合复位或铸造进行保守治疗,而只有少数患者需要手术治疗。手术选择包括电镀,经皮克氏针,刚性髓内钉,和灵活的髓内钉。这取决于病人的年龄,骨折部位,粉碎,和伴随的伤害。这里,我们介绍了一个有趣的病例,该患者在骨折部位出现了异常病变。在手术过程中,该病变被刮除,并用可注射的合成Cerament骨空隙填充剂填充(骨支撑AB,隆德,瑞典),后来形成骨骼并允许骨骼重塑。
    Paediatric distal tibial and fibular fractures are seen quite regularly in orthopaedic trauma practice. Most patients are managed conservatively with closed reduction or casting while only a selected few required surgical treatment. Surgical options include plating, percutaneous Kirschner wires, rigid intramedullary nails, and flexible intramedullary nailing. This is dependent upon the patient\'s age, fracture site, comminution, and concomitant injuries. Here, we present an interesting case of a patient with an unusual lesion seen at the fracture site. This lesion was curetted out during surgery and filled with an injectable synthetic Cerament bone void filler (Bone Support AB, Lund, Sweden), which later formed into bone and allowed the bone to remodel.
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  • 文章类型: Case Reports
    巴尔通体是一种罕见且很少怀疑的骨髓炎病因。我们介绍了一名10岁女性的腰背痛病例,由于微妙的影像学发现,该病例导致了具有挑战性的诊断检查。诊断为类似骨肿瘤的脊椎Bartonella骨髓炎。
    Bartonella henselae is an unusual and rarely suspected osteomyelitis etiologic agent. We present a case of low back-pain in a 10-year-old female which lead to a challenging diagnostic work-up due to subtle imaging findings. The diagnosis was Bartonella henselae vertebral osteomyelitis mimicking bone tumor.
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