背景:在成人中已经报道了体形与抑郁症状之间的关联。本研究旨在调查多地区亚洲成年人身体形态特异性腹部肥胖与抑郁症状之间的关系。
方法:以2011-2012年中国健康与退休纵向研究和2022-2023年杭州研究为发现和验证数据集,分别。通过BMI类别评估身体形状。腹型肥胖定义为身体形态指数(ABSI)≥75百分位。使用10项流行病学研究中心抑郁量表和老年抑郁量表简短的15项版本测量抑郁,分别。一般线性和多项式逻辑模型用于探索ABSI的关联,腹部肥胖伴抑郁评分和存在,分别。
结果:共有12,229和1210名参与者被纳入发现和验证数据集,分别。在ABSI和抑郁评分之间发现了非线性反向L形关联。腹型肥胖患者的抑郁评分较高(分别为β=0.05,95CI=0.01-0.09;β=0.13,95CI=0.01-0.24)。分层分析表明,在超重成年人中,腹部肥胖与较高的抑郁评分(分别为β=0.09,95CI=0.00-0.17;和β=0.25,95CI=0.05-0.46)和存在(OR=1.46,95CI=1.02-2.10;和OR=3.95,95CI=1.58-9.84;)相关。此外,腹部肥胖与超重女性的抑郁症状有关,但不是男性。
结论:由于观察性研究设计,未解决因果关系。
结论:在亚洲超重成年人中,腹型肥胖与抑郁症状呈正相关,尤其是女性。抑郁症状的预防和早期诊断应侧重于超重女性。
BACKGROUND: The association between body shape and depressive symptoms has been reported in adults. The present study aimed to investigate the association between body shape-specific abdominal obesity and depressive symptoms among multi-regional Asian adults.
METHODS: The 2011-2012 China Health and Retirement Longitudinal Study and 2022-2023 Hangzhou study were used as the discovery and validation datasets, respectively. Body shape was assessed by BMI categories. Abdominal obesity was defined as a body shape index (ABSI) ≥ 75th centile. Depression was measured using 10-item Centre for Epidemiological Studies Depression Scale and Geriatric Depression Scale short 15-item version, respectively. General linear and multinomial logistic models were used to explore the association of ABSI, abdominal obesity with depressive scores and presence, respectively.
RESULTS: A total of 12,229 and 1210 participants were included in the discovery and validation datasets, respectively. A non-linear reverse L-shaped association was found between ABSI and depressive scores. Participants with abdominal obesity had higher depressive scores (β = 0.05, 95%CI = 0.01-0.09; and β = 0.13, 95%CI = 0.01-0.24; respectively). Stratified analyses showed that abdominal obesity was associated with higher depressive scores (β = 0.09, 95%CI = 0.00-0.17; and β = 0.25, 95%CI = 0.05-0.46; respectively) and presence (OR = 1.46, 95%CI = 1.02-2.10; and OR = 3.95, 95%CI = 1.58-9.84; respectively) in overweight adults. Furthermore, abdominal obesity was associated with depressive symptoms among overweight females, but not among males.
CONCLUSIONS: Causal links weren\'t addressed because of the observational study design.
CONCLUSIONS: Abdominal obesity exhibited a positive association with depressive symptoms among Asian overweight adults, particularly in females. Prevention and early diagnosis of depressive symptoms should focus on overweight females.