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  • 文章类型: Journal Article
    背景:本研究旨在确定癌症抗原-125(CA-125)与血清β-人绒毛膜促性腺激素(β-hCG)和孕酮联合用于早期检测异位妊娠(EP)的预测价值。
    方法:在2019年5月至2020年5月之间,横断面研究招募了42例EP和42例IUP在相同胎龄时访问了妇产科,顺化医药学院医院。根据手术(腹腔镜)和术后病理检查诊断EP。
    结果:β-hCG的平均水平存在显着差异(2570mUI/mL与18357.7mUI/mL),孕酮(10.79±8.16ng/mlvs.27.42±4.17ng/ml)和CA-125(26.90±10.26U/mLvs.EP组和IUP组之间的70.61±20.89U/mL)(p<0.001)。在预测EP的早期诊断中,CA-125在30.94U/mL时的灵敏度为89.3%,特异性为87.9%;βhCG在2750mIU/ml时的灵敏度为75%,特异性为78,8%;孕酮在10.24ng/mL时的截值灵敏度为85.7%,特异性为81.8%。CA-125,βhCG的组合,孕酮在EP早期诊断中的敏感性为92.8%,特异性为90.9%。
    结论:血清CA-125水平可单独或与其他标志物联合用于EP的早期诊断。
    This study aimed to determine the predictive value of cancer antigen-125 (CA-125) in combination with serum beta-human chorionic gonadotropin (β-hCG) and progesterone in the early detection of ectopic pregnancy (EP).
    Between May 2019 and May 2020, the cross-sectional study recruited 42 cases of EP and 42 cases of IUP at the same gestational age who visited the Department of Obstetrics and Gynecology, Hospital of Hue University of Medicine and Pharmacy. EP was diagnosed based on surgical (laparoscopy) and postoperative pathology examination.
    There were significant differences of mean level of β-hCG (2570 mUI/mL vs. 18357.7 mUI/mL), progesterone (10.79 ± 8.16 ng/ml vs. 27.42 ± 4.17 ng/ml) and CA-125 (26.90 ± 10.26 U/mL vs. 70.61 ± 20.89 U/mL) between the EP and the IUP groups (p < 0.001). In the prediction of early diagnosis of EP, the cut-off value of CA-125 at 30.94 U/mL has a sensitivity of 89.3% and a specificity of 87,9%; the cut-off value of β hCG at 2750mIU/ml has the sensitivity of 75%, specificity of 78,8%; the cut-off value of progesterone at 10.24 ng/mL has the sensitivity of 85.7%, specificity of 81.8%. A combination of CA-125, β hCG, and progesterone had a sensitivity of 92.8% and a specificity of 90.9% in early diagnosis of EP.
    Serum CA-125 levels can be used independently or in combination with other markers in the early diagnosis of EP.
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  • 文章类型: Journal Article
    语言的区别在于它们如何标记动词和参数之间的依赖关系,例如,通过案例。一项眼动追踪和脑电图图片描述研究了案例标记对巴斯克和瑞士德语句子计划时间过程的影响。虽然德语将未标记的(主格)案例分配给受试者,巴斯克通过符合事实的案例特别标记了代理人的论点。在theta和alpha频带中固定到代理和事件相关同步(ERS),以及α和β带的不同步(ERD)揭示了病例标记对早期句子计划的时间过程的多种影响。发言人在巴斯克与符合实际的代理人准备判决时,决定尽早计划中的案件标记,而具有无标记代理的句子允许延迟跨语言的结构性承诺。这些发现支持句子计划的分层增量说明,并强调了跨语言差异如何影响支撑语言使用的神经动力学。
    Languages differ in how they mark the dependencies between verbs and arguments, e.g., by case. An eye tracking and EEG picture description study examined the influence of case marking on the time course of sentence planning in Basque and Swiss German. While German assigns an unmarked (nominative) case to subjects, Basque specifically marks agent arguments through ergative case. Fixations to agents and event-related synchronization (ERS) in the theta and alpha frequency bands, as well as desynchronization (ERD) in the alpha and beta bands revealed multiple effects of case marking on the time course of early sentence planning. Speakers decided on case marking under planning early when preparing sentences with ergative-marked agents in Basque, whereas sentences with unmarked agents allowed delaying structural commitment across languages. These findings support hierarchically incremental accounts of sentence planning and highlight how cross-linguistic differences shape the neural dynamics underpinning language use.
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  • 文章类型: Journal Article
    一个成年女性(22岁)的基督教正统宗教在沉默的主的祈祷被检查,最常见的,简短的祈祷,目的是在她的经历中可能区分信仰和知识,分析theta和beta脑电节律亚组的行为,这是通过大脑区域的持续和偶尔激活而发生的。参与者没有接受过向自己或其他人宣读祈祷的培训。EEG检查由NihonKohden公司进行,EEG-1200-K神经传真装置,在10/20电极系统中的单极纵向蒙太奇中,旨在确定每个勘探地点的峰值频率值。结果分析方法基于根据相同的峰值频率值将大脑区域连接成3个或更多成员的网络,在theta和beta频率的亚组中观察到,并在观察期间通过接近指数以及激活的连续性和不连续性进行分析。在每个子周期的3s的确定观测样本中(开始,middleandend),从周期的开始到结束,一个2s的窗口以200ms的时滞移动。这导致每个电极和每个实验情况下的六个子样本(静息状态,祈祷的情况)。通过制图公式在亚组中评估了区域的稳定和不稳定活性,该公式相当于theta和beta亚组在心理生理学意义上暗示的状态。结果表明,通过参与者的内心对话独白,有知识和信念的因素,考虑到实验的具体情况和参与者本身,这种现象是可能的,例如她相对年轻的年龄和不足的祈祷练习。本文根据我们的理解和文献中的发现,讨论了暗示知识的区域与与信仰有关的区域之间的联系类型。
    An adult female (22 years) of Christian orthodox religion was examined during the silent Lord\'s prayer, the most common, short prayer, with the aim of possible differentiation between belief and knowledge in her experience, analyzing the behavior of subgroups of theta and beta cerebral EEG rhythms, which occur through constant and occasional activation of cerebral regions. The participant was not trained in reading the prayer to herself or other people. EEG examination was performed by Nihon Kohden Corporation, EEG-1200-K Neurofax apparatus, in the monopolar longitudinal montage in the system of 10/20 electrodes aimed at determining the peak frequency value of each exploratory site. The method of result analysis was based on connecting cerebral regions into networks of 3 or more members according to identical peak frequency value, which was observed within subgroups of theta and beta frequencies and analyzed through a proximity index and continuity and discontinuity of activation during the observed period. Out of the definite observation sample of 3 s from each subperiods (beginning, middle and end), a window of 2 s was moving from the beginning till end of the period with 200-ms time lag. This resulted in six subsamples for each electrode and for each experimental situation (resting state, situation of prayer). Stable and unstable activity of the regions was assessed within subgroups via cartographic formulas equivalent to the states which subgroups of theta and beta imply in psychophysiological sense. The results indicated that through participant\'s inner dialogue-monologue there are elements of both knowledge and belief, and that this phenomenon is possible considering insufficiently specific circumstances of the experiment and the participant herself, such as her relatively young age and insufficient practice of praying. The paper discusses the types of connections between regions which imply knowledge and those related to belief according to our understanding and regarding findings in literature.
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