颅外血管畸形是在胎儿发育期间发展的位于脑外(颅外)的血管的异常形成。它们是由胚胎中血管形成的错误引起的,并且可以影响身体的各个部位,比如头,脖子,脸,和其他地区。有些畸形可能是无症状的,只需要监测,而其他人可能会导致重大的健康问题或美容问题,可能需要医疗干预。很少有研究根据血管畸形的亚型调查全国范围内的发病率和数量死亡率。因此,本研究旨在确定全国范围内与血管畸形相关的发病率和死亡率.这项基于人群的全国性研究评估了2008年至2021年的70,517例血管畸形患者。我们评估了与每种血管畸形亚型相关的发病率和死亡率。此外,Cox回归分析用于评估血管畸形与死亡率之间的关系。总血管的年发病率(每100,000人),静脉,毛细管,动静脉,淋巴畸形分别为9.85、1.48、2.31、0.24和5.82例,分别。血管畸形患者,除了那些有静脉畸形的人,死亡率高于匹配的对照组。此外,在血管畸形亚组中,调整后的死亡率危险比在动静脉畸形中最高.这项研究显示,从2008年到2021年,韩国血管畸形的总体年发病率为每10万人口9.85例。匹配的一般人群死亡率低于血管畸形患者,除了那些有静脉畸形的人.此外,在血管畸形亚组中,与动静脉畸形相关的死亡率校正风险比最高.
Extracranial vascular malformations are abnormal formations of blood vessels located outside the brain (extracranial) that develop during fetal development. They are caused by errors in the formation of blood vessels in the embryo and can affect various parts of the body, such as the head, neck, face, and other regions. Some malformations may be asymptomatic and only require monitoring, while others may cause significant health issues or cosmetic concerns and may need medical intervention. There are very few studies have investigated the nationwide incidence and quantitative mortality of vascular malformations in terms of their subtypes. Thus, this
study aimed to determine the nationwide incidence and mortality associated with vascular malformations. This nationwide population-based
study evaluated 70,517 patients with vascular malformations from 2008 to 2021. We evaluated the incidence and mortality associated with each subtype of vascular malformation. Furthermore, Cox regression analysis was used to evaluate the association between vascular malformation and mortality. The annual incidence (per 100,000 population) of overall vascular, venous, capillary, arteriovenous, and lymphatic malformations was 9.85, 1.48, 2.31, 0.24, and 5.82 cases, respectively. Patients with vascular malformations, except those with venous malformations, had higher mortality than the matched controls. Moreover, among the vascular malformation subgroups, the adjusted hazard ratio of mortality was the highest for arteriovenous malformations. This
study revealed that the overall annual incidence of vascular malformations was 9.85 cases per 100,000 population in Korea from 2008 to 2021. The mortality of the matched general population was lower than that of patients with vascular malformations, except for those with venous malformations. Additionally, the adjusted hazard ratio for mortality associated with arteriovenous malformations was the highest among the vascular malformation subgroups.