在这篇文章中,我们介绍一个成年病人的病例,他们的主要问题是每天持续12小时的幻想和摇摆事件,完全阻止了学校的发展。患者疾病的性质与陷入幻想有关,而不是典型的强迫症。患者先前接受过SSRI组的药物治疗,抗精神病药(不含阿立哌唑)和哌醋甲酯。只有哌醋甲酯显示出一些改善;然而,这让病人感到“思维僵硬”。病人因为自杀未遂而住院,which,正如后来的结果,是自残,无意自杀。住院期间,进行了鉴别诊断,并做出了阿斯伯格综合征的诊断,伴随着沉浸在幻想和刻板行为的世界中。患者服用阿立哌唑的剂量为15mg/d,三周后,健康状况显著改善,包括将发作持续时间从几个小时减少到几十秒。患者对该药物的耐受性良好。病人出院,继续他的学校教育。在文章中,我们提供了单例报告,其中在类似病例中取得了类似的惊人结果。我们还描述了对该药物的这种反应的可能的生理解释。
In this article, we present the
case of an adult patient, whose main problem is episodes of fantasizing and rocking lasting up to 12 hours a day and completely preventing school development. The nature of the disorder in the patient is related to the sinking into fantasies, and not typical obsessions as in OCD. The patient was previously treated with drugs from the SSRI group, neuroleptics (without
aripiprazole) and methylphenidate. Only methylphenidate showed some improvement; however, it made the patient feel ‟stiff in thinking\". The patient was hospitalized because of a suicide attempt, which, as it later turned out, was self-harm with no intention of killing himself. During hospitalization, a differential diagnosis was performed and the diagnosis of Asperger\'s syndrome was made, which was accompanied by immersion in the world of one\'s fantasies and stereotypical behavior. The patient was administered
aripiprazole at a dose of 15 mg/d and after three weeks, a significant improvement in health was achieved, including a reduction in the duration of episodes from several hours to several dozen seconds. The drug is well tolerated by the patient. The patient was discharged from the hospital and continues his school education. In the article, we present single
case reports in which similar spectacular results were achieved in similar cases. We also describe a possible physiological explanation for this response to this drug.