目的:本研究分析,使用雨伞评论,现有关于预防和控制牙髓术后疼痛的药物的系统评价,以指导专业人员选择最有效的药物。
方法:在PubMed(MEDLINE)中进行电子搜索,LILACS,SciELO,EMBASE,Scopus,WebofScience,Cochrane评论,数据归档和网络服务(DANS)数据库检索了17项系统评价。该研究仅包括有或没有荟萃分析的临床试验的系统评价,评估药物在非手术牙髓治疗后减轻疼痛的有效性。
结果:证据表明,类固醇和非甾体抗炎药和阿片类药物可在6至24小时内有效控制疼痛。
结论:地塞米松,泼尼松龙,扑热息痛,主要是布洛芬提供了更高的术后疼痛缓解。审查的证据质量从很低到很高,偏见的风险从低到高,这表明需要精心设计的临床试验来提供确证的证据。
结论:本综述强调制定牙髓治疗后疼痛控制方案的有效性。
OBJECTIVE: This study analyzed, using an umbrella
review, existing systematic reviews on medications to prevent and control postoperative endodontic pain to guide professionals in choosing the most effective drug.
METHODS: An electronic search in the PubMed (MEDLINE), LILACS, SciELO, EMBASE, Scopus, Web of Science, Cochrane Reviews, and Data Archiving and Networked Services (DANS) databases retrieved 17 systematic reviews. The study included only systematic reviews of clinical trials with or without meta-analyses evaluating effectiveness of medications in reducing pain after non-surgical endodontic treatment.
RESULTS: The evidence showed that steroidal and non-steroidal anti-inflammatory drugs and opioids effectively controlled pain within six to 24 h.
CONCLUSIONS: Dexamethasone, prednisolone, paracetamol, and mainly ibuprofen provided higher postoperative pain relief. The quality of evidence of the reviews ranged from very low to high, and the risk of bias from low to high, suggesting the need for well-designed clinical trials to provide confirmatory evidence.
CONCLUSIONS: This
review emphasizes the efficacy of developing protocols for pain control after endodontic therapy.