背景：肿瘤标志物（TM）的不适当使用是一个常见问题。此审核的目的是评估当地指南对普外科部门TM请求模式的影响。
方法：CA125,CA19-9,CA15-3,CEA,在实施本地请求指南之前和之后的两个八个月中，对所有医院手术地点的AFP和HCG请求进行了审核。
结果：干预后，总TM请求减少了32%，而患者请求减少了9.8%。单个TM请求增加，对包含四个或更多TM的面板的请求从279个减少到60个请求（减少78％）。
结论：部门间的合作和当地指南的实施导致了请求行为的变化，最值得注意的是多个TM面板请求的减少。
BACKGROUND: The inappropriate use of tumour markers (TMs) is a common problem. The aim of this audit was to evaluate the impact of local
guidelines on the TM requesting patterns of a General Surgery Department.
METHODS: CA 125, CA 19-9, CA15-3, CEA, AFP and HCG requests from all hospital surgical locations were audited over two periods of eight months before and after the implementation of local requesting
guidelines.
RESULTS: Postintervention, total TM requests decreased by 32% while patient requests decreased by 9.8%. Single TM requesting increased and requests for panels containing four or more TMs decreased from 279 to 60 requests (78% reduction).
CONCLUSIONS: Interdepartmental collaboration and the implementation of local
guidelines have resulted in a change in requesting behaviour, most notably a reduction in multiple TM panel requests.
