abscess

脓肿
  • 文章类型: Journal Article
    肩胛骨下的肌内脓肿是一种罕见的现象,但对于外科医生来说是重要的病理,因为临床恶化可能会迅速且诊断困难。该表现通常模仿具有亚急性肩痛和僵硬的其他常见肩关节病变。早期诊断,抗生素和外科引流对减少关节的传播和破坏至关重要。
    对PubMed和GoogleScholar数据库的搜索确定了肩胛骨下肌内脓肿的病例。收集到的每个病例的数据包括患者的人口统计学,介绍,病理学,手术治疗和结果。作者报告了另一例肩胛骨下脓肿病例。
    我们发现了17例肩胛骨下脓肿,文献中的16个和作者描述的一个案例。17例中有16例(94.1%)在就诊前平均6.7天内出现肩痛和活动范围恶化。使用的手术方法包括后下入路,三角肌胸肌入路和后下外侧入路。
    从有关肩胛骨下肌内脓肿的有限数据,作者提出了以下建议:(1)经验性抗生素涵盖金黄色葡萄球菌+/-耐甲氧西林金黄色葡萄球菌,(2)在所有情况下都应引流;(3)保留肌腱的方法可以在肩胛骨下间隙的大多数位置进入脓肿。
    UNASSIGNED: An intramuscular abscess of the subscapularis is a rare phenomenon but important pathology for surgeons to be aware of because clinical deterioration can be rapid and diagnosis difficult. The presentation often mimics other common shoulder pathologies with subacute shoulder pain and stiffness. Early diagnosis, antibiotics and surgical drainage are critical to reduce the spread and joint destruction.
    UNASSIGNED: A search of PubMed and Google Scholar databases identified cases of subscapular intramuscular abscess. Data collected about each case included patient demographics, presentation, pathology, surgical treatment and outcome. The authors report one additional subscapular abscess case.
    UNASSIGNED: Data from 17 cases of subscapular abscess were found, 16 in the literature and one case described by the authors. Sixteen of 17 cases (94.1%) presented with shoulder pain and reduced range of motion worsening over a mean of 6.7 days prior to presentation. Surgical approaches utilised included a posterior inferomedial approach, deltoid-pectoral approach and one posterior inferolateral approach.
    UNASSIGNED: From the limited data available regarding subscapular intramuscular abscess, the authors make the following recommendations: (1) Empirical antibiotics covering Staphylococcus aureus +/- methicillin-resistant Staphylococcus aureus, (2) drainage is indicated in all cases; and (3) tendon-sparing approaches can access an abscess in most locations within the subscapular space.
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  • 文章类型: Review
    与使用合成的不可吸收网状物的盆腔器官脱垂(POP)手术相关的并发症并不常见(<5%),但可能很严重,可能会极大地降低某些女性的生活质量。在制定这些多学科临床实践建议时,法国国家卫生管理局(HauteAutoritédesanté,HAS)对有关诊断的文献进行了详尽的回顾,预防,和使用合成网处理与POP手术相关的并发症。每个实践建议都分配了一个等级(A,B或C;或专家意见(EO)),这取决于证据水平(临床实践指南)。
    必须告知每位患者与POP手术(EO)相关的风险。
    在POP手术期间,不建议通过阴道途径(C级)使用血管收缩溶液进行阴道浸润。在POP手术后,不建议通过阴道途径(C级)放置阴道填塞。在腹腔镜骶骨结肠切除术期间,当海角看起来非常危险或严重的粘连阻止进入椎骨前韧带时,每次手术应讨论替代手术技术,包括侧网腹腔镜悬吊术,子宫骶韧带悬吊,开腹网眼手术,或通过阴道途径(EO)进行手术。
    当诊断出膀胱损伤时,建议通过缝合膀胱修复,使用缓慢的再吸收缝合线,加上当损伤位于三角(EO)水平时,监测输尿管的渗透性(膀胱修复前后)。当诊断出膀胱损伤时,膀胱修复后,假体网(聚丙烯或聚酯材料)可以放置在修复的膀胱和阴道之间,如果缝合质量好。在POP网状手术的这种情况下,膀胱修复后膀胱导管插入的推荐持续时间为5至10天(EO)。
    输尿管修复后,如果远离输尿管修复术(EO),则可以继续进行骶骨结肠切除术并放置网状物。
    无论采用何种方法,当直肠损伤发生时,后网孔不应放置在直肠和阴道壁(EO)之间。关于前网,建议使用大孔单丝聚丙烯网(EO)。在这种情况下不建议使用聚酯网(EO)。
    阴道壁修复后,可以放置前或后微孔聚丙烯网,如果发现维修质量令人满意(EO)。在阴道壁修复(EO)后不应使用聚酯网。
    不管手术方法如何,建议静脉内预防使用抗生素(氨基青霉素+β-内酰胺酶抑制剂:皮肤切开前30分钟+/-如果手术持续时间更长,则在2小时后重复)(EO).当脊椎盘炎在骶骨结肠切除术后被诊断出来时,治疗应该由多学科小组讨论,特别是脊柱专家(风湿病学家,骨科医生,神经外科医生)和传染病专家(EO)。当骨盆脓肿发生在合成网状骶骨结肠切除术后,建议尽快进行完全的网眼去除,结合术中细菌学样本的收集,引流收集和靶向抗生素治疗(EO)。在某些情况下(没有败血症的迹象,大孔单丝聚丙烯类型1目,先前的微生物文件和多学科咨询,以选择抗生素治疗的类型和持续时间),与密切监测患者有关。
    建议通过腹部入路(EO)放置合成网片后进行腹膜闭合。
    建议出现泌尿系症状(膀胱出口梗阻症状,膀胱过度活动症或尿失禁)(EO)。建议在手术结束时或POP手术(B级)后48小时内取出膀胱导管。POP手术后,应检查膀胱排空和排尿后残留。放电前(EO)。当POP手术后发生术后尿潴留时,建议进行留置导尿,并更喜欢间歇性自导尿(EO)。
    POP手术前,应询问患者长期和慢性术后疼痛的危险因素(疼痛敏化,异常性疼痛,慢性盆腔或非盆腔疼痛)(EO)。关于预防术后疼痛,建议进行预,围手术期和术后多模式疼痛治疗(B级)。建议术中使用氯胺酮预防术后慢性盆腔疼痛,特别是对于有危险因素的患者(术前疼痛致敏,异常性疼痛,慢性盆腔或非盆腔疼痛)(EO)。术后阿片类药物的处方应限制数量和持续时间(C级)。当骶棘固定后出现对I级和II级镇痛药有抗性的急性神经性疼痛(坐骨神经痛或阴部神经痛)时,建议对悬挂式缝线移除(EO)进行再干预。当POP手术后发生慢性术后疼痛时,建议通过DN4问卷(EO)系统地寻求支持神经性疼痛的论据。当POP手术后发生慢性术后盆腔疼痛时,应确定中枢致敏,因为它需要在慢性疼痛科(EO)进行咨询.关于肌筋膜疼痛综合征(与肌筋膜触发点引起的肌张力增加相关的临床疼痛状况),当POP手术后发生慢性术后疼痛时,建议检查肛提肌,梨状肌和闭孔肌,从而识别合成网格(EO)路径上的触发点。当肌筋膜疼痛综合征与POP手术(EO)后的慢性术后疼痛相关时,建议进行盆底肌肉训练并放松肌肉。盆底肌肉训练失败后(3个月),建议讨论手术切除合成网片,在多学科讨论小组会议(EO)期间。当触发点位于网格(EO)的路径上时,指示合成网格的部分移除。当POP手术后出现弥漫性(无触发点)慢性术后疼痛时,应在多学科讨论小组会议上讨论合成网状物的完全移除。有或没有中枢致敏或神经性疼痛综合征(EO)。
    当POP手术后重新出现术后性交困难时,应讨论网片的手术切除(EO)。
    为了降低阴道网状物暴露的风险,当在骶骨结肠切除术期间需要子宫切除术时,推荐子宫次全切除术(C级).当无症状的阴道大孔单丝聚丙烯网暴露时,不建议进行系统成像。当发生阴道聚酯网暴露时,骨盆+/-腰椎MRI(EO)应用于寻找脓肿或脊椎盘炎,考虑到与此类材料相关的更大感染风险。当无症状的阴道网暴露小于1cm2时,没有性交的女性发生,患者应接受观察(无治疗)或局部雌激素治疗(EO).然而,如果病人愿意,可以提供网格的部分切除。当无症状的阴道网状物暴露超过1cm2时,或者如果女性有性交,或者如果是聚酯假体,部分网片切除,立即或局部雌激素治疗后,应该提供(EO)。当出现有症状的阴道网状物暴露时,但没有感染并发症,建议通过阴道途径手术切除网状物的暴露部分(EO),而不是系统地完全切除网格。骶骨结肠切除术后,仅在存在脓肿或脊椎盘炎(EO)的情况下,才需要完全切除网状物(通过腹腔镜检查或剖腹手术)。当第一次再次手术后阴道网眼暴露复发时,患者应由专门研究此类并发症(EO)的经验丰富的团队进行治疗.
    对于在使用网状物加固的POP手术后阴道暴露于不可吸收的缝合线的女性,应通过阴道途径(EO)去除缝合线。仅当诊断出阴道网状物暴露或相关脓肿时,才建议移除周围的网状物。
    当膀胱网状物暴露时,建议去除网状物的暴露部分(B级)。应与患者讨论两种替代方案(全部或部分网状物去除),并应在多学科讨论小组会议(EO)期间进行辩论。
    Complications associated with pelvic organ prolapse (POP) surgery using a synthetic non-absorbable mesh are uncommon (<5%) but may be severe and may hugely diminish the quality of life of some women. In drawing up these multidisciplinary clinical practice recommendations, the French National Authority for Health (Haute Autorité de santé, HAS) conducted an exhaustive review of the literature concerning the diagnosis, prevention, and management of complications associated with POP surgery using a synthetic mesh. Each recommendation for practice was allocated a grade (A,B or C; or expert opinion (EO)), which depends on the level of evidence (clinical practice guidelines).
    UNASSIGNED: Each patient must be informed concerning the risks associated with POP surgery (EO).
    UNASSIGNED: Vaginal infiltration using a vasoconstrictive solution is not recommended during POP surgery by the vaginal route (grade C). The placement of vaginal packing is not recommended following POP surgery by the vaginal route (grade C). During laparoscopic sacral colpopexy, when the promontory seems highly dangerous or when severe adhesions prevent access to the anterior vertebral ligament, alternative surgical techniques should be discussed per operatively, including colpopexy by lateral mesh laparoscopic suspension, uterosacral ligament suspension, open abdominal mesh surgery, or surgery by the vaginal route (EO).
    UNASSIGNED: When a bladder injury is diagnosed, bladder repair by suturing is recommended, using a slow resorption suture thread, plus monitoring of the permeability of the ureters (before and after bladder repair) when the injury is located at the level of the trigone (EO). When a bladder injury is diagnosed, after bladder repair, a prosthetic mesh (polypropylene or polyester material) can be placed between the repaired bladder and the vagina, if the quality of the suturing is good. The recommended duration of bladder catheterization following bladder repair in this context of POP mesh surgery is from 5 to 10 days (EO).
    UNASSIGNED: After ureteral repair, it is possible to continue sacral colpopexy and place the mesh if it is located away from the ureteral repair (EO).
    UNASSIGNED: Regardless of the approach, when a rectal injury occurs, a posterior mesh should not be placed between the rectum and the vagina wall (EO). Concerning the anterior mesh, it is recommended to use a macroporous monofilament polypropylene mesh (EO). A polyester mesh is not recommended in this situation (EO).
    UNASSIGNED: After vaginal wall repair, an anterior or a posterior microporous polypropylene mesh can be placed, if the quality of the repair is found to be satisfactory (EO). A polyester mesh should not be used after vaginal wall repair (EO).
    UNASSIGNED: Regardless of the surgical approach, intravenous antibiotic prophylaxis is recommended (aminopenicillin + beta-lactamase inhibitor: 30 min before skin incision +/- repeated after 2 h if surgery lasts longer) (EO). When spondylodiscitis is diagnosed following sacral colpopexy, treatment should be discussed by a multidisciplinary group, including especially spine specialists (rheumatologists, orthopedists, neurosurgeons) and infectious disease specialists (EO). When a pelvic abscess occurs following synthetic mesh sacral colpopexy, it is recommended to carry out complete mesh removal as soon as possible, combined with collection of intraoperative bacteriological samples, drainage of the collection and targeted antibiotic therapy (EO). Non-surgical conservative management with antibiotic therapy may be an option (EO) in certain conditions (absence of signs of sepsis, macroporous monofilament polypropylene type 1 mesh, prior microbiological documentation and multidisciplinary consultation for the choice of type and duration of antibiotic therapy), associated with close monitoring of the patient.
    UNASSIGNED: Peritoneal closure is recommended after placement of a synthetic mesh by the abdominal approach (EO).
    UNASSIGNED: Preoperative urodynamics is recommended in women presenting with urinary symptoms (bladder outlet obstruction symptoms, overactive bladder syndrome or incontinence) (EO). It is recommended to remove the bladder catheter at the end of the procedure or within 48 h after POP surgery (grade B). Bladder emptying and post-void residual should be checked following POP surgery, before discharge (EO). When postoperative urine retention occurs after POP surgery, it is recommended to carry out indwelling catheterization and to prefer intermittent self-catheterization (EO).
    UNASSIGNED: Before POP surgery, the patient should be asked about risk factors for prolonged and chronic postoperative pain (pain sensitization, allodynia, chronic pelvic or non-pelvic pain) (EO). Concerning the prevention of postoperative pain, it is recommended to carry out a pre-, per- and postoperative multimodal pain treatment (grade B). The use of ketamine intraoperatively is recommended for the prevention of chronic postoperative pelvic pain, especially for patients with risk factors (preoperative painful sensitization, allodynia, chronic pelvic or non-pelvic pain) (EO). Postoperative prescription of opioids should be limited in quantity and duration (grade C). When acute neuropathic pain (sciatalgia or pudendal neuralgia) resistant to level I and II analgesics occurs following sacrospinous fixation, a reintervention is recommended for suspension suture removal (EO). When chronic postoperative pain occurs after POP surgery, it is recommended to systematically seek arguments in favor of neuropathic pain with the DN4 questionnaire (EO). When chronic postoperative pelvic pain occurs after POP surgery, central sensitization should be identified since it requires a consultation in a chronic pain department (EO). Concerning myofascial pain syndrome (clinical pain condition associated with increased muscle tension caused by myofascial trigger points), when chronic postoperative pain occurs after POP surgery, it is recommended to examine the levator ani, piriformis and obturator internus muscles, so as to identify trigger points on the pathway of the synthetic mesh (EO). Pelvic floor muscle training with muscle relaxation is recommended when myofascial pain syndrome is associated with chronic postoperative pain following POP surgery (EO). After failure of pelvic floor muscle training (3 months), it is recommended to discuss surgical removal of the synthetic mesh, during a multidisciplinary discussion group meeting (EO). Partial removal of synthetic mesh is indicated when a trigger point is located on the pathway of the mesh (EO). Total removal of synthetic mesh should be discussed during a multidisciplinary discussion group meeting when diffuse (no trigger point) chronic postoperative pain occurs following POP surgery, with or without central sensitization or neuropathic pain syndromes (EO).
    UNASSIGNED: When de novo postoperative dyspareunia occurs after POP surgery, surgical removal of the mesh should be discussed (EO).
    UNASSIGNED: To reduce the risk of vaginal mesh exposure, when hysterectomy is required during sacral colpopexy, subtotal hysterectomy is recommended (grade C). When asymptomatic vaginal macroporous monofilament polypropylene mesh exposure occurs, systematic imaging is not recommended. When vaginal polyester mesh exposure occurs, pelvic +/- lumbar MRI (EO) should be used to look for an abscess or spondylodiscitis, given the greater risk of infection associated with this type of material. When asymptomatic vaginal mesh exposure of less than 1 cm2 occurs in a woman with no sexual intercourse, the patient should be offered observation (no treatment) or local estrogen therapy (EO). However, if the patient wishes, partial excision of the mesh can be offered. When asymptomatic vaginal mesh exposure of more than 1 cm2 occurs or if the woman has sexual intercourse, or if it is a polyester prosthesis, partial mesh excision, either immediately or after local estrogen therapy, should be offered (EO). When symptomatic vaginal mesh exposure occurs, but without infectious complications, surgical removal of the exposed part of the mesh by the vaginal route is recommended (EO), and not systematic complete excision of the mesh. Following sacral colpopexy, complete removal of the mesh (by laparoscopy or laparotomy) is only required in the presence of an abscess or spondylodiscitis (EO). When vaginal mesh exposure recurs after a first reoperation, the patient should be treated by an experienced team specialized in this type of complication (EO).
    UNASSIGNED: For women presenting with vaginal exposure to non-absorbable suture thread following POP surgery with mesh reinforcement, the suture thread should be removed by the vaginal route (EO). Removal of the surrounding mesh is only recommended when vaginal mesh exposure or associated abscess is diagnosed.
    UNASSIGNED: When bladder mesh exposure occurs, removal of the exposed part of the mesh is recommended (grade B). Both alternatives (total or partial mesh removal) should be discussed with the patient and should be debated during a multidisciplinary discussion group meeting (EO).
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  • 文章类型: Meta-Analysis
    目的:欧洲结肠直肠学会(ESCP)指南开发小组(GDG)的主要目标是生产高质量的,基于证据的隐腺肛瘘的管理指南,来自多学科小组的输入并使用透明的,可重复的方法。
    方法:本项目复制了ESCP先前发布的指南开发方法。指南开发过程遵循了AGREE-S工具包的要求。在该方法中可以确定六个阶段。第一阶段设定了准则的范围,解决了接受二级护理的成年患者的肛周脓肿和隐腺肛瘘的诊断和治疗管理。本指南的目标人群是二级保健医生和有兴趣了解肛瘘各种手术干预临床证据的患者。第二阶段涉及GDG的配制。GDG由21位结肠直肠学家组成,三个研究员,放射科医生和方法学家.选择利益相关者是因为他们在肛瘘管理中的临床和学术参与以及代表ESCP成员之间的地理差异。从患者组中招募了5名患者以审查指南草案。这些患者参加了两次虚拟会议,讨论证据并建议修改。在第三阶段,患者/人群,干预,比较和结果问题由GDG制定。GDG批准了250个问题,并选择了45个问题纳入指南。在第四阶段,关键和重要的结果被确认纳入.重要的结果是疼痛和伤口愈合。关键结果是瘘管愈合,瘘复发和尿失禁。这些结果构成了文献检索纳入标准的一部分。在第五阶段,对MEDLINE(Ovid)进行了文献检索,PubMed,Embase(Ovid)和GDG八个团队的Cochrane系统评论数据库。数据被提取并提交给GDG在指南草案中审查。最近的系统审查被列为优先事项。通过使用Reviewmanager进行新的荟萃分析,将自最近的系统综述以来发表的研究纳入我们的分析。在第六阶段,提出了建议,使用建议的分级,评估,发展,和评估,在GDG的三个虚拟会议中。
    结果:在涵盖肛周脓肿和隐腺肛瘘的诊断和治疗管理的七个部分中,有42条建议。
    结论:这是关于使用AGREE企业规定的方法管理隐腺肛瘘的最新国际指南。
    OBJECTIVE: The primary aim of the European Society of Coloproctology (ESCP) Guideline Development Group (GDG) was to produce high-quality, evidence-based guidelines for the management of cryptoglandular anal fistula with input from a multidisciplinary group and using transparent, reproducible methodology.
    METHODS: Previously published methodology in guideline development by the ESCP has been replicated in this project. The guideline development process followed the requirements of the AGREE-S tool kit. Six phases can be identified in the methodology. Phase one sets the scope of the guideline, which addresses the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula in adult patients presenting to secondary care. The target population for this guideline are healthcare practitioners in secondary care and patients interested in understanding the clinical evidence available for various surgical interventions for anal fistula. Phase two involved formulation of the GDG. The GDG consisted of 21 coloproctologists, three research fellows, a radiologist and a methodologist. Stakeholders were chosen for their clinical and academic involvement in the management of anal fistula as well as being representative of the geographical variation among the ESCP membership. Five patients were recruited from patient groups to review the draft guideline. These patients attended two virtual meetings to discuss the evidence and suggest amendments. In phase three, patient/population, intervention, comparison and outcomes questions were formulated by the GDG. The GDG ratified 250 questions and chose 45 for inclusion in the guideline. In phase four, critical and important outcomes were confirmed for inclusion. Important outcomes were pain and wound healing. Critical outcomes were fistula healing, fistula recurrence and incontinence. These outcomes formed part of the inclusion criteria for the literature search. In phase five, a literature search was performed of MEDLINE (Ovid), PubMed, Embase (Ovid) and the Cochrane Database of Systematic Reviews by eight teams of the GDG. Data were extracted and submitted for review by the GDG in a draft guideline. The most recent systematic reviews were prioritized for inclusion. Studies published since the most recent systematic review were included in our analysis by conducting a new meta-analysis using Review manager. In phase six, recommendations were formulated, using grading of recommendations, assessment, development, and evaluations, in three virtual meetings of the GDG.
    RESULTS: In seven sections covering the diagnostic and therapeutic management of perianal abscess and cryptoglandular anal fistula, there are 42 recommendations.
    CONCLUSIONS: This is an up-to-date international guideline on the management of cryptoglandular anal fistula using methodology prescribed by the AGREE enterprise.
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  • 文章类型: Journal Article
    在低收入国家(LIC),骨感染的管理是一个巨大的挑战。大量的患者属于儿科年龄组。儿童和青少年表现出良好的骨愈合潜力,提供主要依赖于感染骨的生物学反应的治疗选择。本文的目的是强调LIC患者的治疗选择,这是基于说明治疗原则的临床案例,专注于骨骼反应和愈合潜力。首先,识别紧急情况很重要。由于骨感染引起的患者败血症是一种危及生命的疾病,需要通过脓肿切口立即进行手术治疗。应根据外科医生的经验和当地条件量身定制,以避免不必要的并发症,比如过度出血,骨折或骨丢失。在非脓毒症患者中,不复杂的病例应与复杂的病例区分开来,因为最初的病例通常只需要脓肿切口,特别是在小孩子身上,没有任何其他重大手术干预。生物力学稳定性和骨形成能力,软组织状况和关节受累是区分简单病例和复杂病例的决定性因素。中心治疗柱是用简单的方法固定感染的骨,比如巴黎的石膏,支架或外部固定。这旨在提供足够的稳定性以允许新骨形成,其随后减小感染部位的尺寸并且可以桥接先前感染的不愈合部位或骨缺陷。在大多数情况下,不进行抗生素治疗,因为抗生素不可用或负担不起.严重的软组织缺损仍然是一个主要挑战,因为微血管手术经验通常需要可靠的覆盖,建议转诊到极少数的专业中心之一。严重的骨缺损也应在具有足够专业知识的骨重建手术中心进行治疗。定期随访对于确保愈合和避免疾病恶化很重要。通过这些治疗原则可以实现令人鼓舞的成功率。然而,不应忘记,这些国家的贫困,包括有限的医疗保健,仍然是世界上最重要的问题之一。
    In low-income countries (LIC), the management of bone infections is a huge challenge. A high number of patients are in the pediatric age group. Children and adolescents exhibit good bone healing potential offering treatment options that mainly rely on the biological response of the infected bone. The purpose of this article is to highlight treatment options for these patients in LIC, which is based on clinical cases that illustrate the principles of the treatment, focusing on bone reaction and healing potential. First, identification of emergency cases is of importance. Sepsis of the patient due to bone infections is a life-threatening disease that requires immediate surgical attention with abscess incision. It should be tailored to the surgeon\'s experience and local conditions to avoid unwanted complications, such as excessive bleeding, fracture or bone loss. In non-septic patients, uncomplicated cases should be distinguished from complicated cases as the first might often require only abscess incision, particularly in small children, without any other major surgical intervention. Biomechanical stability and bone formation capacity, soft tissue conditions and joint involvement are decisive factors differentiating uncomplicated from complicated cases. Central treatment column is the immobilization of the infected bone with simple methods, such as plaster of Paris, braces or external fixation. This is intended to provide sufficient stability to allow for new bone formation that subsequently downsizes the infection site and that can bridge previously infected non-union sites or bone defects. In most cases, antibiotic treatment is not performed as antibiotics are not available or affordable. Severe soft tissue defects remain a major challenge as microvascular surgical experience is often required for reliable coverage, for which referral to one of the very few specialized centers is recommended. Major bone defects should also be treated in centers with sufficient expertise for bone reconstruction procedures. Regular follow-ups are important to ensure healing and to avoid aggravation of the disease. Encouraging success rates can be achieved by these treatment principles. However, it should not be forgotten that poverty in these countries, including limited access to health care, remains one of the world\'s most important problems.
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  • 文章类型: English Abstract
    Hidradenitis suppurativa is a chronic and recurrent inflammatory dermatosis characterized by the presence of inflammatory nodules and abscesses in the apocrine gland-rich areas that may progress to suppurative fistulas and scars. Despite being considered one of the dermatological conditions with the greatest impact on patient quality of life, it is often underdiagnosed. Hidradenitis suppurativa, especially in its severe forms, is associated with numerous comorbidities, so a holistic and multidisciplinary perspective is crucial for the management of these patients. The therapeutic approach is complex and challenging. The medical treatment options are diverse and must be adapted to clinical presentation and disease severity. Surgical therapy should be considered as an adjuvant to medical treatment, particularly in refractory cases and in the presence of scars or anatomical and/or functional mutilation. These recommendations reflect the main aspects of the management of the patient with hidradenitis suppurativa and are addressed to all healthcare professionals who take part in their follow-up.
    A hidradenite supurativa é uma dermatose inflamatória crónica e recorrente que se caracteriza pela presença de nódulos inflamatórios e abcessos nas áreas ricas em glândulas apócrinas, que podem evoluir para fístulas supurativas e cicatrizes. Apesar de ser considerada uma das patologias dermatológicas com maior impacto na qualidade de vida dos doentes, é frequentemente subdiagnosticada. A hidradenite supurativa, sobretudo nas suas formas mais graves, associa-se a diversas comorbilidades, pelo que é fundamental adotar uma perspetiva holística e multidisciplinar na gestão destes doentes. A abordagem terapêutica é complexa e desafiante. A terapêutica médica é multifacetada e deve ser adaptada à apresentação clínica e gravidade da doença. A terapêutica cirúrgica deverá ser equacionada como adjuvante à terapêutica médica, em particular nos casos refratários e perante cicatrizes ou mutilação anatómica e/ou funcional. As presentes recomendações pretendem reunir os principais aspetos da abordagem ao doente com hidradenite supurativa e destinam-se a todos os profissionais de saúde envolvidos no seu acompanhamento.
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  • 文章类型: Journal Article
    建议儿童在生命的前4至6个月进行纯母乳喂养,此后添加补充食品。这是保护孩子和母亲健康的最生态的方式。需要对卫生专业人员进行培训,以避免在3个方面传递不一致的信息:1)实施这3个预测因素:安全的皮肤对皮肤,第一次母乳喂养,和全天候住宿;2)教学和监控:i)清醒和进食节奏的早期迹象,ii)定位和闭锁,和iii)有效转移的迹象;3)如果出现困难(例如,牛奶产量不足,疼痛,乳头破裂,engorgement).乳腺炎或脓肿期间应继续母乳喂养。超声引导的针抽吸在治疗脓肿中是有益的。Précis:提供信息以使卫生专业人员能够更好地支持母乳喂养并帮助解决最常见的困难的妇女,从而促进母乳喂养的开始和持续时间。
    Exclusive breastfeeding is recommended for children for the first 4 to 6 months of life, with complementary foods added thereafter. It is the most ecological way of protecting the child\'s and mother\'s health. Training of health professionals is required to avoid transmitting inconsistent information in 3 areas: 1) implementing these 3 predictors: safe skin-to-skin, first breastfeed, and rooming-in 24/7; 2) teaching and monitoring: i) early signs of waking and feeding rhythms, ii) positioning and latching, and iii) signs of effective transfer; and 3) referring women to specialized support services if difficulties arise (eg, inadequate milk production, pain, cracked nipples, engorgement). Breastfeeding should continue during mastitis or an abscess. Ultrasound-guided needle aspiration is beneficial in treating an abscess. Précis: Information is provided to enable health professionals to better support breastfeeding and help women with the most common difficulties, thus promoting breastfeeding initiation and duration.
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  • 文章类型: Journal Article
    背景:自从我们上一次发表克罗恩病患者肛周瘘的治疗算法以来,研究人员提出了一种针对肛门病变的靶向策略系统组合疗法,和干细胞注射的适应症。在没有强大出版物的情况下,法国国家学会(法国国家学会[SNFCP])希望使用Delphi方法建立小组共识。
    方法:从2020年10月到2021年1月,一个科学委员会和胃肠病学家和外科医生小组建立了答案,并在2020年11月的一次全国会议上提交给SNFCP成员。对三个问题进行了澄清和重新表述,然后在SNFCP成员的第三轮也是最后一轮磋商中提交。
    结果:目标定义为在每个领域获得的反应(症状,物理和放射学评估)可以被认为是令人满意的,不需要加强治疗管理。通过协商一致,临床评价治疗疗效所需的时间为6个月.对磁共振成像(MRI)的反应应包括在6个月时没有10毫米或更大尺寸的集合,在12个月时,主束的T1和T2序列中的高强度明显减少或完全消失。免疫抑制剂与肿瘤坏死因子抑制剂的系统关联未达到阿达木单抗的共识水平(50%),但只是英夫利昔单抗(70%)。大多数受访者认为一个人失败了,甚至两行不同的生物疗法是注射干细胞的潜在适应症。
    结论:这些发现加强了包括MRI评估在内的复合目标的重要性,并强调需要精确的评估时间。仅建议使用英夫利昔单抗进行联合治疗。注射干细胞是二线或三线选择。
    BACKGROUND: Since our last publication of algorithms for the management of perianal fistulas in patients with Crohn\'s disease, researchers have proposed a treat to target strategy systematic combotherapy for anal lesions, and indications for stem cell injection. In the absence robust publications, the Société Nationale Française de Coloproctologie (French National Society of Coloproctology [SNFCP]) wished to establish a group consensus using the Delphi method.
    METHODS: From October 2020 to January 2021, a scientific committee and panel of gastroenterologists and surgeons established answers which were submitted to the members of the SNFCP during a national conference in November 2020. Three questions were clarified and reformulated, and then submitted during a third and final round of consultation of members of the SNFCP.
    RESULTS: The target was defined as being the response obtained in every domain (symptoms, physical and radiological evaluation) which could be considered satisfactory, without the need to intensify therapeutic management. By consensus, the time required for clinical evaluation of the efficacy of treatment was 6 months. A response on magnetic resonance imaging (MRI) should include the absence of a collection of 10 mm or more in size at 6 months, and a frank decrease or complete disappearance of hyperintensity in T1 and T2 sequences of the main tract at 12 months. Systematic association of an immunosuppressant with tumor necrosis factor inhibitors did not reach the consensus level for adalimumab (50%), but just did for infliximab (70%). The majority of the respondents considered failure of one, or even two lines of different biotherapies to be potential indications for injection of stem cells.
    CONCLUSIONS: These findings reinforce the importance of composite targets including MRI evaluation, and underscore the need for precise timing of evaluation. Combotherapy is only recommended with infliximab. Injection of stem cells is a second- or third-line option.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    尽管目前有治疗炎症性肠病的治疗选择,在紧急情况下仍然经常需要手术,尽管近年来进行的病例数量似乎有所减少。世界急诊外科学会决定在专家共识会议上进行辩论,在紧急情况下,围绕炎症性肠病的管理的主要相关问题,需要为急性护理和急诊外科医生提供重点指导。
    一组经验丰富的外科医生和胃肠病学家被提名来制定项目指导委员会分配的主题并回答问题。每位专家都对选择进行审查的研究进行了精确的分析和分级。2019年6月在荷兰奈梅亨举行的第六届世界急诊外科学会共识会议上讨论并表决了声明和建议。
    复杂的炎症性肠病需要多学科的方法,因为该患者群体的复杂性和在紧急情况下的疾病谱,目的是获得具有良好功能结局的安全手术,并在适当情况下降低造口率。
    Despite the current therapeutic options for the treatment of inflammatory bowel disease, surgery is still frequently required in the emergency setting, although the number of cases performed seems to have decreased in recent years. The World Society of Emergency Surgery decided to debate in a consensus conference of experts, the main pertinent issues around the management of inflammatory bowel disease in the emergent situation, with the need to provide focused guidelines for acute care and emergency surgeons.
    A group of experienced surgeons and gastroenterologists were nominated to develop the topics assigned and answer the questions addressed by the Steering Committee of the project. Each expert followed a precise analysis and grading of the studies selected for review. Statements and recommendations were discussed and voted at the Consensus Conference of the 6th World Society of Emergency Surgery held in Nijmegen (The Netherlands) in June 2019.
    Complicated inflammatory bowel disease requires a multidisciplinary approach because of the complexity of this patient group and disease spectrum in the emergency setting, with the aim of obtaining safe surgery with good functional outcomes and a decreasing stoma rate where appropriate.
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  • 文章类型: Journal Article
    背景:扁桃体切除术是一种常见的外科手术,主要用于复发性扁桃体炎。苏格兰大学间指导网络(SIGN)于1998年引入了指南,以改善扁桃体切除术的患者选择,并减少出血等手术并发症对患者的潜在伤害。自《指导意见》出台以来,扁桃体炎及其并发症的入院人数有所增加。分析了20年来的国家医院事件统计数据,以评估扁桃体切除术的趋势,扁桃体切除术后出血,扁桃体炎及其并发症参考指导,临床价值有限的程序以及相关的成本和收益。
    方法:通过PubMed和Cochrane图书馆进行文献检索,以确定相关研究。询问医院事件统计数据,并随着时间的推移比较相关数据,以评估与实施国家指南相关的趋势。
    结果:在分析期间,颈深间隙感染的发病率增加了近五倍,与SIGN指导前相比,纵隔炎10倍,扁桃体周围脓肿1.7倍。遵循有限的临床价值实施程序,颈深间隙感染的发生率增加了2.4倍,与临床调试组配给前相比,纵隔炎4.1倍,扁桃体周围脓肿1.4倍。扁桃体切除术和相关出血(1-2%)的发生率保持相对稳定,为46,299(1999),而49,447(2009)和49,141(2016)。尽管英格兰的人口在20年期间增加了700万。
    结论:扁桃体炎入院率及其并发症的增加似乎与SIGN指导和临床委托组配给扁桃体切除术的日期密切相关,并且是在英国人口增加的背景下。向日间扁桃体切除术的发展减少了手术后的卧床率,但扁桃体炎和深颈部空间感染的入院人数增加抵消了这一点。有时需要长时间的重症监护和长期的康复过程。2017年英格兰治疗扁桃体炎并发症的总费用估计约为7300万英镑。相比之下,扁桃体切除术和治疗扁桃体切除术后出血的费用为5600万英镑。在引入SIGN指导之前,扁桃体切除术的总费用估计为7100万英镑,扁桃体炎及其并发症的费用为800万英镑。
    BACKGROUND: Tonsillectomy is a common surgical procedure performed chiefly for recurrent tonsillitis. The Scottish Intercollegiate Guidance Network (SIGN) introduced guidelines in 1998 to improve patient selection for tonsillectomy and reduce the potential harm to patients from surgical complications such as haemorrhage. Since the introduction of the guidance, the number of admissions for tonsillitis and its complications has increased. National Hospital Episode Statistics over a 20-year period were analysed to assess the trends in tonsillectomy, post-tonsillectomy haemorrhage, tonsillitis and its complications with reference to the guidance, procedures of limited clinical value and the associated costs and benefits.
    METHODS: A literature search was conducted via PubMed and the Cochrane Library to identify relevant research. Hospital Episode Statistics data were interrogated and relevant data compared over time to assess trends related to the implementation of national guidance.
    RESULTS: Over the period analysed, the incidence of deep neck space infections has increased almost five-fold, mediastinitis ten-fold and peritonsillar abscess by 1.7-fold compared with prior to SIGN guidance. Following procedures of limited clinical value implementation, the incidence of deep neck space infections has increased 2.4-fold, mediastinitis 4.1-fold and peritonsillar abscess 1.4-fold compared with immediately prior to clinical commissioning group rationing. The rate of tonsillectomy and associated haemorrhage (1-2%) has remained relatively constant at 46,299 (1999) compared with 49,447 (2009) and 49,141 (2016), despite an increase in the population of England by seven million over the 20-year period.
    CONCLUSIONS: The rise in admissions for tonsillitis and its complications appears to correspond closely to the date of SIGN guidance and clinical commissioning group rationing of tonsillectomy and is on the background of a rise in the population of the UK. The move towards daycase tonsillectomy has reduced bed occupancy after surgery but this has been counteracted by an increase in admissions for tonsillitis and deep neck space infections, sometimes requiring lengthy intensive care stays and a protracted course of rehabilitation. The total cost of treating the complications of tonsillitis in England in 2017 is estimated to be around £73 million. The cost of tonsillectomy and treating post-tonsillectomy haemorrhage is £56 million by comparison. The total cost per annum for tonsillectomy prior to the introduction of SIGN guidance was estimated at £71 million with tonsillitis and its complications accounting for a further £8 million.
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