顾名思义，是包含签名WRKY结构域的转录因子(TF)，因此以它命名。自1994年发现以来，它们已经在植物中进行了充分的研究，并在模型植物中探索了大约74个WRKY基因，单独的拟南芥。然而,现在对这些转录因子（TFs）的研究不仅仅局限于模型植物。它们也在农作物中得到了广泛的研究，因为它们在压力以及成长和发展中的巨大贡献。这里,在这次审查中,我们描述了WRKYTFs从识别到起源的故事，绑定机制，结构及其在调节植物发育和胁迫生理方面的贡献。基于高通量转录组学的数据也为了解WRKYTFs在植物中的全面和详细功能打开了大门。的确,每个WRKY成员在调节基因表达中的详细功能作用是为全面了解其在植物胁迫生理和发育过程中的作用铺平道路。
WRKY as the name suggests, are the transcription factors (TFs) that contain the signature
WRKY domains, hence named after it. Since their discovery in 1994, they have been well studied in plants with exploration of approximately 74
WRKY genes in the model plant, Arabidopsis alone. However, the study of these transcription factors (TFs) is not just limited to model plant now. They have been studied widely in crop plants as well, because of their tremendous contribution in stress as well as in growth and development. Here, in this
review, we describe the story of
WRKY TFs from their identification to their origin, the binding mechanisms, structure and their contribution in regulating plant development and stress physiology. High throughput transcriptomics-based data also opened a doorway to understand the comprehensive and detailed functioning of
WRKY TFs in plants. Indeed, the detailed functional role of each and every
WRKY member in regulating the gene expression is required to pave the path to develop holistic understanding of their role in stress physiology and developmental processes in plants.
