在智利,自1998年以来,在3次胃肠炎暴发中发现了副溶血性弧菌。最近一次疫情发生在2005年夏季,影响了10,000多人,其中一人死亡。受影响的个体出现以下一种或多种症状:腹泻,恶心,呕吐,腹痛和/或发烧。只有6%的患者检测到粪便白细胞。3次暴发中的主要血清型是大流行的O3:K6菌株。通过在粪便培养物中分离和鉴定副溶血性弧菌和/或通过建立流行病学联系来确认诊断。副溶血弧菌分离株对四环素100%敏感,环丙沙星和氯霉素,对氨苄青霉素普遍耐药。由于2005年疫情对公共卫生的影响,卫生部呼吁成立一个负责流行病学审查的国家工作队,疫情的临床和微生物学特征,并提出管理指南。
In Chile Vibrio parahaemolyticus has been detected in 3 gastroenteritis outbreaks since 1998. The most recent outbreak occurred during the summer of 2005, affecting over 10,000 people of whom one died. Affected individuals presented with one or more of the following symptoms: diarrhea, nausea, vomiting, abdominal pain and/or fever. Fecal white blood cells were detected in only 6% of patients. The predominant serotype in the 3 outbreaks was the pandemic O3:K6 strain. Diagnosis was confirmed by isolation and identification of V. parahaemolyticus in stool cultures and/or by establishing an epidemiological link. V. parahaemolyticus isolates were 100% susceptible to tetracycline, ciprofloxacin and chloramphenicol, and universally resistant to ampicillin. Due to the public health impact of the 2005 outbreak, the Ministry of Health called for a National Task Force mandated to review epidemiological, clinical and microbiological features of the outbreak and to propose management
guidelines.