Veins

静脉
  • 文章类型: Journal Article
    目的:严重的手部电损伤经常发生在关节等功能区域;由于手的可见性,修复需要同时注意外观和功能。本研究旨在介绍使用改进的前臂静脉皮瓣成功修复手部电损伤的临床经验。
    方法:从2020年到2022年,诊断出15例严重手部电伤,包括10名男性和5名女性。其中,在第一个网络空间修复了6个案例,4在拇指上,3在食指中,2中指,2在无名指中,和2在小手指。静脉皮瓣大小2.0cm×1.8cm~12cm×4.0cm。所有患者均使用改良的前臂静脉皮瓣进行修复。随访时间5~8个月。
    结果:所有皮瓣均存活,无严重并发症。所有患者对术后美学和手的功能感到满意。
    结论:改良的前臂静脉皮瓣是修复手部电损伤的一种简单可靠的方法。
    OBJECTIVE: Severe hand electrical injuries often occur in functional areas such as joints; the repair requires attention to both appearance and function due to the visibility of the hand. This study aimed to present the clinical experience of successfully repairing hand electrical injuries using improved forearm venous flaps.
    METHODS: From 2020 to 2022, 15 cases of severe hand electrical injuries were diagnosed, including 10 males and 5 females. Among them, 6 cases were repaired in the first web space, 4 in the thumb, 3 in the index finger, 2 in the middle finger, 2 in the ring finger, and 2 in the little finger. The size of venous flaps ranged from 2.0 cm × 1.8 cm to 12 cm × 4.0 cm. All patients underwent repair using improved forearm venous flaps. The follow-up period ranged from 5 to 8 months.
    RESULTS: All flaps survived without serious complications. All patients were satisfied with the postoperative aesthetics and function of their hands.
    CONCLUSIONS: The improved forearm venous flap is a simple and reliable method for repairing hand electrical injuries.
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  • 文章类型: Journal Article
    背景:在急诊科难以进行界标引导的IV入路的患者中,超声用于外周静脉(PIV)插管。Esmarch绷带在目标肢体上的远端到近端应用已被建议作为增加静脉尺寸和易于插管的方法。
    方法:这项研究是一项单盲交叉随机对照试验,比较了超声下的贵宾静脉大小,并使用标准IV止血带(“止血带+Esmarch”)与使用标准IV止血带相比单独使用标准IV止血带。还将止血带+Esmarch的参与者不适与单独的标准IV止血带进行了比较。
    结果:使用22名健康志愿者测量有无Esmarch绷带的贵重静脉大小。两组的贵宾静脉大小没有差异,止血带+Esmarch组的平均直径为6.0±1.5mm,对照组为6.0±1.4mm,p=0.89。两组之间的不适评分(从0到10)不同,止血带+Esmarch组的平均不适评分为2.1,标准IV止血带单独组的平均不适评分为1.1(p<0.001)。
    结论:这项研究表明,使用Esmarch绷带不会增加健康志愿者的贵重静脉大小,但与不适的轻度增加有关。
    BACKGROUND: Ultrasound is used for peripheral intravenous (PIV) cannulation in patients with difficult landmark-guided IV access in the Emergency Department. Distal-to-proximal application of an Esmarch bandage on the target limb has been suggested as a method for increasing vein size and ease of cannulation.
    METHODS: This study was a single-blinded crossover randomized controlled trial comparing basilic vein size under ultrasound with use of an Esmarch bandage in addition to standard IV tourniquet (\"tourniquet + Esmarch\") compared to use of a standard IV tourniquet alone. Participant discomfort with the tourniquet + Esmarch was also compared to that with standard IV tourniquet alone.
    RESULTS: Twenty-two healthy volunteers were used to measure basilic vein size with and without the Esmarch bandage. There was no difference in basilic vein size between the two groups, with a mean diameter of 6.0 ± 1.5 mm in the tourniquet + Esmarch group and 6.0 ± 1.4 mm in the control group, p = 0.89. Discomfort score (from 0 to 10) was different between the groups, with a mean discomfort score of 2.1 in the tourniquet + Esmarch group and 1.1 in the standard IV tourniquet alone group (p < 0.001).
    CONCLUSIONS: This study showed that the use of an Esmarch bandage does not increase basilic vein size in healthy volunteers but is associated with a mild increase in discomfort.
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  • 文章类型: Journal Article
    为了解决手指静脉识别的几个常见问题,本研究提出了一种基于小样本的轻量级手指静脉识别算法。首先,为了使处理后的图像能够模拟手指静脉在低温下的一种情况,从而提高算法模型的泛化能力。通过减少VGG-19中卷积层和全连接层的数量,可以给出一个轻量级网络。同时,部分卷积层的激活函数被替换,以保护能够成功更新的网络权值。在那之后,在改进的网络体系结构中引入了多注意力机制,以提高提取重要特征的能力。最后,基于迁移学习的策略被用来减少模型训练阶段的训练时间。老实说,很明显,本文提出的手指静脉识别算法在识别精度上有很好的表现,鲁棒性和速度。实验结果表明,识别准确率达到98.45%左右,与现有的一些算法相比,具有更好的性能。
    To address several common problems of finger vein recognition, a lightweight finger vein recognition algorithm by means of a small sample has been proposed in this study. First of all, a Gabor filter is applied to deal with the images for the purpose of that these processed images can simulate a kind of situation of finger vein at low temperature, such that the generalization ability of the algorithm model can be improved as well. By cutting down the amount of convolutional layers and fully connected layers in VGG-19, a lightweight network can be given. Meanwhile, the activation function of some convolutional layers is replaced to protect the network weight that can be updated successfully. After then, a multi-attention mechanism is introduced to the modified network architecture to result in improving the ability of extracting important features. Finally, a strategy based on transfer learning has been used to reduce the training time in the model training phase. Honestly, it is obvious that the proposed finger vein recognition algorithm has a good performance in recognition accuracy, robustness and speed. The experimental results show that the recognition accuracy can arrive at about 98.45%, which has had better performance in comparison with some existing algorithms.
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  • 文章类型: Journal Article
    背景和目的:面部血管解剖在生理背景和手术干预中起着关键作用。虽然有关于面部动脉和静脉个体过程的数据,到目前为止,脉管系统的空间关系研究得不好。这项研究的目的是评估面部动脉的过程,静脉和分支相对于另一个。材料和方法:在总共90个减半的内脏中,面部血管注射有色乳胶。进行了解剖,研究了面部血管的关系,测量下颌骨下缘的距离。此外,包括唇血管和角状血管在内的分支进行了评估。结果:在下颌骨的底部,在所有情况下,面动脉位于面静脉前方,平均距离为6.2mm(范围为0-15mm),三例两条船相邻。在所有情况下都存在有角的静脉,而角动脉仅存在于34.4%的病例中。结论:面动脉和静脉的主干产生一个相当独立的过程,面动脉总是位于静脉的前面,而他们的树枝,尤其是唇血管,表现出更紧密的关系。
    Background and Objectives: Facial vascular anatomy plays a pivotal role in both physiological context and in surgical intervention. While data exist on the individual course of the facial artery and vein, to date, the spatial relationship of the vasculature has been ill studied. The aim of this study was to assess the course of facial arteries, veins and branches one relative to another. Materials and Methods: In a total of 90 halved viscerocrania, the facial vessels were injected with colored latex. Dissection was carried out, the relation of the facial vessels was studied, and the distance at the lower margin of the mandible was measured. Furthermore, branches including the labial and angular vessels were assessed. Results: At the base of the mandible, the facial artery was located anterior to the facial vein in all cases at a mean distance of 6.2 mm (range 0-15 mm), with three cases of both vessels adjacent. An angular vein was present in all cases, while an angular artery was only present in 34.4% of cases. Conclusions: The main trunk of the facial artery and vein yields a rather independent course, with the facial artery always located anterior to the vein, while their branches, especially the labial vessels, demonstrate a closer relationship.
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  • 文章类型: Journal Article
    经皮扩张气管切开术期间的出血事件令人担忧,大多数病例发生在血管解剖结构未识别和意外解剖变异的患者。然而,这种变异的程度尚不清楚.为了解决这个知识差距,我们的研究旨在全面绘制一组成年患者的喉血管解剖图.
    对颈部软组织进行超声评估,从甲状软骨到第三气管环,两侧横向延伸2厘米。我们将该区域细分为12个区域,包括四个内侧部分和八个外侧部分。使用预先计划的表格来记录每个区域中动脉或静脉的存在。结果报告为赔率比,95%CIs,和相应的P值。
    从2023年8月14日至2023年11月13日,在帕多瓦大学医院招募了500名患者。在所有研究区域中都确定了动脉和静脉(从最低1.0%-46.4%变化)。从环甲膜到第三气管环,从中线到喉旁正中区域,血管的存在逐渐增加。
    考虑到动脉和静脉的患病率,特别是在通常进行气管造口术的地区,我们强烈主张在进行此类手术之前进行常规超声评估.
    BACKGROUND: Bleeding incidents during percutaneous dilatational tracheostomy are concerning, and most cases occur in patients with unrecognized and unanticipated anatomical variations in the vascular anatomy. However, the extent of this variation remains unclear. To address this knowledge gap, our study aimed to comprehensively map laryngeal vascular anatomy in a cohort of adult patients.
    METHODS: Ultrasound assessments of the soft tissue in the neck were performed, spanning from the thyroid cartilage to the third tracheal ring and extending 2 cm laterally on both sidesperformed. We subdivided this area into 12 zones comprising four medial and eight lateral sections. A pre-planned form was used to document the presence of arteries or veins in each zone. The results are reported as odds ratios, 95% CIs, and corresponding P values.
    RESULTS: Five-hundred patients were enrolled from August 14, 2023, to November 13, 2023, at the University Hospital of Padua. Arteries and veins were identified in all investigated zones (varying from a minimum of 1.0%-46.4%). The presence of invessels progressively increased from the cricothyroid membrane to the third tracheal ring and from the midline to the paramedian laryngeal area.
    CONCLUSIONS: Given the prevalence of arteries and veins, particularly in areas where tracheostomies are commonly performed, we strongly advocate for routine ultrasound assessments before such procedures are performed.
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  • 文章类型: Observational Study
    背景:虽然罕见,深静脉血栓形成是一种潜在的危及生命的膝关节镜并发症。在尼泊尔,很少有文献分析关节镜检查后的深静脉血栓形成。这项研究旨在确定在术后2周和6周未接受化学预防的膝关节镜检查患者深静脉血栓形成的发生率。分别。该研究还旨在通过使用Caprini风险评估模型来评估这些患者的深静脉血栓形成风险。
    方法:这项前瞻性观察研究是在AKB中心进行的,B和B医院Gwarko,Lalitpur,为期16个月。所有接受关节镜膝关节手术符合纳入标准的患者均纳入研究。主要结局指标是术后2周和6周深静脉血栓形成的发生率。根据Caprini风险评估模型,次要结果指标是风险组中深静脉血栓形成的患病率。
    结果:在研究期间接受关节镜膝关节手术的612例患者中,2例(0.33%)在6周随访时诊断为the和小腿静脉的超声检查,发生了深静脉血栓。高危人群的患病率为0.33%(1/307),极高危人群为5.88%(1/17)。
    结论:在我们的研究中,膝关节镜检查后无化学预防的深静脉血栓形成的发生率较低。极高风险组患者深静脉血栓形成的发生率较高,因此,建议在随访期间密切监测此类患者。
    BACKGROUND: Although rare, deep vein thrombosis is a potentially life-threatening complication of knee arthroscopy. There are scanty literature analysing deep vein thrombosis after arthroscopy in Nepal. This study aimed to identify the prevalence of deep vein thrombosis in patients undergoing knee arthroscopy without chemoprophylaxis postoperatively at 2 weeks and 6 weeks, respectively. The study also aimed to estimate the risk of deep vein thrombosis in these patients by using Caprini Risk Assessment Model.
    METHODS: This prospective observational study was conducted at AKB center, B and B Hospital, Gwarko, Lalitpur, over a period of 16 months. All patients who underwent arthroscopy knee surgeries fulfilling the inclusion criteria were included in the study. The primary outcome measure was the prevalence of deep vein thrombosis as diagnosed by compression color-coded ultrasonography of the popliteal vein and calf vein at 2 weeks and 6 weeks postoperatively. The secondary outcome measure was the prevalence of deep vein thrombosis in the risk groups according to Caprini Risk Assessment Model.
    RESULTS: Out of 612 patients who underwent arthroscopic knee surgeries during the study period, 2 patients (0.33%) developed deep vein thrombosis at 6 weeks follow-up as diagnosed with ultrasonography of the popliteal and calf veins. The prevalence rate in high-risk group was 0.33% (1 in 307) and in very high-risk group was 5.88% (1 in 17).
    CONCLUSIONS: There was a low prevalence of deep vein thrombosis without chemoprophylaxis following knee arthroscopy in our study. There was higher prevalence of deep vein thrombosis in very high-risk group patients, so close monitoring of such patients during follow-up is recommended.
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  • 文章类型: Journal Article
    背景:人口调查中报告的贫血患病率估计值可能因血液样本来源(毛细血管或静脉)和用于血红蛋白(Hb)测定的分析设备(血液学自动分析仪或便携式血红蛋白计)而异。
    方法:这种多站点(柬埔寨,埃塞俄比亚,危地马拉,黎巴嫩,尼日利亚,坦桑尼亚)研究使用三种HemoCue®Hb模型(201,301、801)。将测量值与参考值进行比较:血液学自动分析仪(AA)中的静脉血,并通过回归校准或HemoCue®Hb的平均差异进行调整。静脉,毛细管池,和单滴毛细血管血液标本的准确性和精密度进行评估。
    结果:通过HemoCue®Hb301测量的静脉血表现出正平均误差,而HemoCue®Hb201+和801的反应与参考相比是非定向的。使用静脉血将所有设备的参考协调平均误差调整为<1·0g/L。所有部位的静脉血精度最高(±5至16g/L),单滴毛细管最低(±9至37g/L),和中间(±9至28g/L)的毛细血管池血液标本。不同地点的不精确性不同,尤其是两个毛细血管血液样本,建议不同水平的人员技能。
    结论:研究结果表明,准确和精确的Hb测定需要静脉血。由于测量变异性高,应禁止使用单滴毛细血管血液。进一步的研究应评估用于此目的的毛细血管池血液的可行性和可靠性。HemoCue®Hb装置的准确性可以通过针对通过AA评估的静脉血结果的标准化来提高。
    BACKGROUND: Anemia prevalence estimates reported in population surveys can vary based on the blood specimen source (capillary or venous) and analytic device (hematology autoanalyzers or portable hemoglobinometers) used for hemoglobin (Hb) determination.
    OBJECTIVE: This study aimed to compare accuracy and precision of Hb measurement in three blood specimen types on three models of hemoglobinometers against the results from venous blood from the same individuals measured on automated analyzers (AAs).
    METHODS: This multisite (Cambodia, Ethiopia, Guatemala, Lebanon, Nigeria, and Tanzania) study assessed Hb measurements in paired venous and capillary blood specimens from apparently healthy women (aged 15-49 y) and children (aged 12-59 mo) using three HemoCue® Hb models (201+, 301, and 801). Measurements were compared against reference values: venous blood in hematology AA and adjusted via regression calibration or mean difference in HemoCue® Hb. Venous, capillary pool, and single-drop capillary blood specimens were assessed for accuracy and precision.
    RESULTS: Venous blood measured using HemoCue® Hb 301 exhibited a positive mean error, whereas responses in HemoCue® Hb 201+ and 801 were nondirectional compared with the reference. Adjustment with the reference harmonized mean errors for all devices across study sites to <1.0 g/L using venous blood. Precision was highest for venous blood (±5-16 g/L) in all sites, lowest for single-drop capillary (±9-37 g/L), and intermediate (±9-28 g/L) for capillary pool blood specimen. Imprecision differed across sites, especially with both capillary blood specimens, suggesting different levels of personnel skills.
    CONCLUSIONS: Findings suggest that venous blood is needed for accurate and precise Hb determination. Single-drop capillary blood use should be discouraged owing to high measurement variability. Further research should evaluate the viability and reliability of capillary pool blood for this purpose. Accuracy of HemoCue® Hb devices can be improved via standardization against results from venous blood assessed using AA.
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  • 文章类型: Journal Article
    背景:血管畸形(VM)通常在出生时出现,并与患者相应地生长。它们在血管类型和组织受累方面可以有很大差异,和上肢(UE)虚拟机可能对儿童构成独特的功能和美学挑战。鉴于硬化疗法和药物等手术和非手术技术的出现,有必要对UEVM的手术管理进行当代审查.
    方法:我们对2010年至2021年在费城儿童医院接受VM手术治疗的所有患者进行了回顾性研究。人口统计,病变特征,治疗(包括之前的非手术疗法),并发症,并记录最终结果.审查了操作说明的操作日期,切除深度,闭合类型,和当前的程序术语代码。
    结果:研究了67例88例手术患者。患者平均年龄为5.8岁,64%的白人和67%的男性。静脉畸形(34%)和淋巴管畸形(19%)最为常见,解剖位置最常见的是手部(33%)和前臂(25%)。平均病灶直径4.2cm,尽管这因位置而异(例如,2.9cm,手;11.1厘米,胸壁)。58名患者(87%)接受了手术切除作为他们的指标程序,9人在手术前接受了硬化治疗。39例患者(60%)进行了皮下切除,其余的需要筋膜下或肌肉内切除。几乎所有切除手术都是关闭的(97%)。在有记录的随访的53名患者中,32名患者(60%)在最后一次就诊时已完全解决病变。在这32例没有临床证据的患者中,有30例仅进行了1次切除手术。
    结论:上肢VM由不同血管类型的不同条件组成,尺寸,深度,和解剖部位。手术切除UE的VM是安全有效的。大多数VM在1次手术后被完全切除,并且经常闭合,主要并发症发生率相对较低。未来的工作应该调查UE的VM的所有治疗选项的决策和结果,以获得最佳的功能和美观性。
    BACKGROUND: Vascular malformations (VMs) typically appear at birth and grow commensurately with patients. They can vary broadly in vessel type and tissue involvement, and upper extremity (UE) VMs can pose unique functional and aesthetic challenges in children. Given the advent of operative and nonoperative technologies like sclerotherapy and medications, a contemporary review of the surgical management of UE VMs is warranted.
    METHODS: We performed a retrospective review of all patients who had surgical management of VMs from 2010 to 2021 at The Children\'s Hospital of Philadelphia. Demographics, lesion characteristics, treatment (including preceding nonsurgical therapies), complications, and final outcomes were recorded. Operative notes were reviewed for date of operation, depth of excision, type of closure, and current procedural terminology code.
    RESULTS: Sixty-seven patients with 88 procedures were studied. Average patient age was 5.8 years, with 64% White and 67% male. Venous (34%) and lymphatic (19%) malformations were most common, and anatomic locations were most frequently on the hand (33%) and forearm (25%). The average lesion diameter was 4.2 cm, although this varied by location (eg, 2.9 cm, hand; 11.1 cm, chest wall). Fifty-eight patients (87%) underwent surgical excision as their index procedure, and 9 had sclerotherapy before surgery. Thirty-nine patients (60%) had subcutaneous excisions, and the remainder required subfascial or intramuscular excisions. Nearly all excisions were closed primarily (97%). Of the 53 patients with documented follow-up, 32 patients (60%) had complete resolution of their lesion as of their final visit. Thirty of these 32 patients with no clinical evidence of residual VM had only 1 surgery for excision.
    CONCLUSIONS: Upper extremity VMs were composed of diverse conditions with varying vessel types, size, depth, and anatomic sites. Surgical excision of VMs of the UE was safe and effective. A majority of VMs were fully excised after 1 procedure and frequently closed primarily with relatively low complication rates. Future work should investigate decision-making and outcomes of all treatment options of VMs of the UE for optimal functionality and aesthetics.
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  • 文章类型: Journal Article
    目的:肾上腺静脉采样(AVS)是鉴定原发性醛固酮增多症亚型的关键。然而,促肾上腺皮质激素(ACTH)刺激在AVS中的价值仍存在争议。
    方法:在这项前瞻性研究中,我们在59例原发性醛固酮增多症患者中采用标准方案,研究了持续ACTH输注对双侧同时发生AVS的表现和判读的作用.我们分析了ACTH前后AVS的选择性指数和侧化指数,并评估了ACTH后不同侧化指数截止点的肾上腺切除术患者的预后。
    结果:双侧肾上腺静脉置管的成功率从ACTH前的84%提高到ACTH后的95%。50%的患者在ACTH后的侧化指数下降,30%的患者在ACTH之前表现为单侧原发性醛固酮增多症,而在ACTH之后表现为双侧原发性醛固酮增多症。肾上腺切除术后原发性醛固酮增多症患者的结果表明,无论侧向化指数如何,所有患者在ACTH后至少达到4或低于4,均取得了临床和生化成功。受试者工作特征曲线显示,ACTH刺激后的偏侧指数截止2.58产生了最佳的偏侧阈值,灵敏度为73.1%,特异性为92.9%。
    结论:ACTH刺激增加了原发性醛固酮增多症患者的AVS成功率,在某些情况下降低了偏侧化指数,并降低了已确定的单侧原发性醛固酮增多症的比例,导致一些患者失去疾病治愈的机会。与至少4的侧化指数相比,ACTH刺激后至少2.58的侧化指数的截止点较低,具有更好的侧化诊断准确性。
    OBJECTIVE: Adrenal venous sampling (AVS) is key for primary aldosteronism subtype identification. However, the value of adrenocorticotropic hormone (ACTH) stimulation in AVS is still controversial.
    METHODS: In this prospective study, we investigated the role of continuous ACTH infusion on the performance and interpretation of bilateral simultaneous AVS using a standard protocol in 59 primary aldosteronism patients. We analyzed the selectivity index and lateralization index in AVS pre and post-ACTH and estimated the prognosis of patients who underwent adrenalectomy with different cutoff points of lateralization index post-ACTH.
    RESULTS: The confirmed success rate of bilateral adrenal vein catheterization increased from 84% pre-ACTH to 95% post-ACTH. Fifty percent of the patients had a decline in lateralization index post-ACTH, 30% of patients showed unilateral primary aldosteronism pre-ACTH but bilateral primary aldosteronism post-ACTH according to lateralization index at least 2 pre-ACTH and lateralization index at least 4 post-ACTH. The outcomes of the patients with primary aldosteronism after adrenalectomy indicated that all patients achieved clinical and biochemical success regardless of lateralization index at least 4 or less than 4 post-ACTH. Receiver operating characteristic curves showed that lateralization index cutoff 2.58 post-ACTH stimulation yielded the best threshold in lateralization with a sensitivity of 73.1% and a specificity of 92.9%.
    CONCLUSIONS: ACTH stimulation increased the AVS success rates in patients with primary aldosteronism, reduced lateralization index in some cases and decreased the proportion of identified unilateral primary aldosteronism, resulting in some patients losing the opportunity for disease cure. Compared with lateralization index at least 4, a lower cutoff point of lateralization index at least 2.58 after ACTH stimulation has better accuracy of lateralization diagnosis.
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  • 文章类型: Journal Article
    目的:由于可变的测量误差,静脉血气(VBG)在评估急性呼吸衰竭时并非始终被认为是动脉血气(ABG)的合适替代品。在这种情况下,慢性通气衰竭患者的生理稳定性可能会改善一致性。
    方法:需要ABG进行睡眠或通气滴定研究的成年人在每个ABG之前或之后抽取VBG,以随机顺序。检查了静脉-动脉相关性和二氧化碳张力(PCO2)的一致性,pH值,氧张力(PO2)和氧饱和度(SO2)。
    结果:我们分析了61例患者的115对VBG-ABG。动脉和静脉测量结果与PCO2(r=0.84)和pH(r=0.72)相关(p<0.05),但不是PO2或SO2。调整后的平均静脉动脉差异(95%的一致性界限)为PCO2的5.0mmHg(-4.4至14.4);pH值-0.02(-0.09至0.04);PO2的-34.3mmHg(-78.5至10.0);SO2的-23.9%(-61.3至13.5)。从背侧手获得的VBG显示较低的平均PCO2静脉动脉差异(p<0.01)。≥45.8mmHg的静脉PCO2阈值对动脉高碳酸血症的敏感性>95%,因此,以下测量结果可以排除没有ABG的诊断.≥53.7mmHg的静脉PCO2阈值对动脉高碳酸血症的特异性>95%,所以这样的读数可以被认为是诊断的。接收器工作特性曲线下的面积为0.91,表明判别能力很高。
    结论:静脉PCO2<45.8mmHg或≥53.7mmHg可以排除或诊断高碳酸血症,分别,在接受睡眠研究的患者中,但是VBG对于精度很重要的ABG来说是很差的替代品。
    背景:注册:澳大利亚新西兰临床试验注册;名称:睡眠研究中动脉和血气分析的比较;标识符:ACTRN12617000562370;URLhttps://www。anzctr.org.au/Trial/Registration/TrialReview.aspx?id=372717。
    OBJECTIVE: Venous blood gases (VBGs) are not consistently considered suitable surrogates for arterial blood gases (ABGs) in assessing acute respiratory failure due to variable measurement error. The physiological stability of patients with chronic ventilatory failure may lead to improved agreement in this setting.
    METHODS: Adults requiring ABGs for sleep or ventilation titration studies had VBGs drawn before or after each ABG, in a randomized order. Veno-arterial correlation and agreement were examined for carbon dioxide tension (PCO2), pH, oxygen tension (PO2), and oxygen saturation (SO2).
    RESULTS: We analyzed 115 VBG-ABG pairs from 61 patients. Arterial and venous measures were correlated (P < .05) for PCO2 (r = .84) and pH (r = .72), but not for PO2 or SO2. Adjusted mean veno-arterial differences (95% limits of agreement) were +5.0 mmHg (-4.4 to +14.4) for PCO2; -0.02 (-0.09 to +0.04) for pH; -34.3 mmHg (-78.5 to +10.0) for PO2; and -23.9% (-61.3 to +13.5) for SO2. VBGs obtained from the dorsal hand demonstrated a lower mean PCO2 veno-arterial difference (P < .01). A venous PCO2 threshold of ≥ 45.8 mmHg was > 95% sensitive for arterial hypercapnia, so measurements below this can exclude the diagnosis without an ABG. A venous PCO2 threshold of ≥ 53.7 mmHg was > 95% specific for arterial hypercapnia, so such readings can be assumed diagnostic. The area under the receiver operating characteristic curve of 0.91 indicated high discriminatory capacity.
    CONCLUSIONS: A venous PCO2 < 45.8 mmHg or ≥ 53.7 mmHg would exclude or diagnose hypercapnia, respectively, in patients referred for sleep studies, but VBGs are poor surrogates for ABGs where precision is important.
    BACKGROUND: Registry: Australian New Zealand Clinical Trials Register; Name: A comparison of arterial and blood gas analyses in sleep studies; URL: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=372717; Identifier: ACTRN12617000562370.
    BACKGROUND: Lindstrom SJ, McDonald CF, Howard ME, et al. Venous blood gases in the assessment of respiratory failure in patients undergoing sleep studies: a randomized study. J Clin Sleep Med. 2024;20(8):1259-1266.
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