Upper extremity

上肢
  • 文章类型: Journal Article
    上肢的评估对于指导康复周期至关重要。基于观察的评估的缺点包括主观性和序数量表的粗略分辨率。运动学评估产生客观的定量指标,但是成本高昂且不切实际的设置阻碍了吸收。我们的目标是研究计算机视觉(CV)获取饮酒任务运动学指标的可行性和准确性,这是中风康复研究中推荐的。我们使用适度的相机和开源机器学习解决方案实现了用于上肢运动学评估的CV。探索可行性,在饮酒任务期间,招募了10名神经典型参与者进行重复的运动学测量。为了调查准确性,同时使用基于标记的运动捕捉系统,并对以下运动学指标的误差进行了量化:运动单位数(NMU),干线位移(TD),和运动时间(MT)。在所有参与者试验中,使用CV成功获得了饮酒任务的运动学指标。与基于标记的运动捕捉相比,运动学指标的组平均值无显著差异.NMU的平均误差,TD,MT为-0.12个单位,3.4mm,和0.15s,分别。Bland-Altman分析显示没有偏见。可以使用CV测量饮酒任务的运动学指标,和初步发现支持准确性。需要对神经发散人群进行进一步研究,以确定CV对中风后上肢的运动学评估的有效性。
    Assessment of the upper limb is critical to guiding the rehabilitation cycle. Drawbacks of observation-based assessment include subjectivity and coarse resolution of ordinal scales. Kinematic assessment gives rise to objective quantitative metrics, but uptake is encumbered by costly and impractical setups. Our objective was to investigate feasibility and accuracy of computer vision (CV) for acquiring kinematic metrics of the drinking task, which are recommended in stroke rehabilitation research. We implemented CV for upper limb kinematic assessment using modest cameras and an open-source machine learning solution. To explore feasibility, 10 neurotypical participants were recruited for repeated kinematic measures during the drinking task. To investigate accuracy, a simultaneous marker-based motion capture system was used, and error was quantified for the following kinematic metrics: Number of Movement Units (NMU), Trunk Displacement (TD), and Movement Time (MT). Across all participant trials, kinematic metrics of the drinking task were successfully acquired using CV. Compared to marker-based motion capture, no significant difference was observed for group mean values of kinematic metrics. Mean error for NMU, TD, and MT were - 0.12 units, 3.4 mm, and 0.15 s, respectively. Bland-Altman analysis revealed no bias. Kinematic metrics of the drinking task can be measured using CV, and preliminary findings support accuracy. Further study in neurodivergent populations is needed to determine validity of CV for kinematic assessment of the post-stroke upper limb.
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  • 文章类型: Journal Article
    该研究的目的是评估使用LunaEMG(肌电图)多功能机器人进行的评估者之间和评估者之间的一致性,一种评估中风患者上肢本体感觉的工具。
    该研究是在一组慢性中风患者中进行的。共有126名患者参与了这项研究,包括78名女性和48名男性,平均年龄近60岁(平均值=59.9)。使用LunaEMG诊断和康复机器人进行本体感觉测量,以评估左右上肢。检查由两名评估者进行,两次,相隔两周.在评估者和考试之间比较结果。
    对右手和左手进行的测量的高度一致性由类别间相关系数(分别为0.996-0.998和0.994-0.999)和皮尔逊的线性相关反映,在所有情况下,在评分者之间和评分者之间的协议分析中,右手和左手的线性相关都非常高(r=1.00)。
    由LunaEMG诊断和康复机器人进行的测量表明,在评估慢性中风患者的上肢本体感觉方面,评估者之间和评估者之间具有很高的一致性。研究结果表明,LunaEMG是一种可靠的工具,可以有效评估中风后的上肢本体感觉。
    UNASSIGNED: The aim of the study was to assess the inter-rater and intra-rater agreement of measurements performed with the Luna EMG (electromyography) multifunctional robot, a tool for evaluation of upper limb proprioception in individuals with stroke.
    UNASSIGNED: The study was conducted in a group of patients with chronic stroke. A total of 126 patients participated in the study, including 78 women and 48 men, on average aged nearly 60 years (mean = 59.9). Proprioception measurements were performed using the Luna EMG diagnostic and rehabilitation robot to assess the left and right upper limbs. The examinations were conducted by two raters, twice, two weeks apart. The results were compared between the raters and the examinations.
    UNASSIGNED: High consistency of the measurements performed for the right and the left hand was reflected by the interclass correlation coefficients (0.996-0.998 and 0.994-0.999, respectively) and by Pearson\'s linear correlation which was very high (r = 1.00) in all the cases for the right and the left hand in both the inter-rater and intra-rater agreement analyses.
    UNASSIGNED: Measurements performed by the Luna EMG diagnostic and rehabilitation robot demonstrate high inter-rater and intra-rater agreement in the assessment of upper limb proprioception in patients with chronic stroke. The findings show that Luna EMG is a reliable tool enabling effective evaluation of upper limb proprioception post-stroke.
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  • 文章类型: Journal Article
    背景:考虑到日常生活活动(ADL)的局限性以及心力衰竭(HF)患者改善的影响,适当评估上肢功能容量和ADL很重要。
    目的:评估HF患者的上肢功能容量和ADL,并将其与健康对照组进行比较。
    方法:本研究包括30名HF患者和健康对照。采用6分钟Pegboard环测试(6PBRT)评估上肢功能能力,根据Londrina协议,6分钟步行测试(6MWT)的运动能力,手测力计周围肌肉力量,和呼吸困难通过改良医学研究理事会量表(MMRC)。对于性能测试,还测量了测试前(休息)和测试后(性能后)值。
    结果:射血分数≤50%的HF患者与对照组的年龄相似(52.63±6.2和50.03±6.5岁,分别)和性别(每组25名女性)(p>0.05)。患者在Londrina方案中显示出总测试时间的统计学显着增加,在6PBRT中移动的环较少(p<0.0001)。在Londrina方案的患者中,测试后呼吸困难(p=0.03)和测试前手臂疲劳(p<0.0001)更高。在试验前和试验后心率较低的患者中,通过时间相互作用有统计学意义的组(F=4.80,p=0.03),测试后呼吸困难(p<0.0001),6PBRT患者的测试后手臂疲劳(p=0.005)更高。
    结论:证据显示HF患者上肢功能能力下降。与健康对照相比,患者需要更多的时间来执行ADL。
    BACKGROUND: Considering the limitations in activities of daily living (ADL) and the impact of improvements in patients with heart failure (HF), appropriate assessment of upper extremity functional capacity and ADL is important.
    OBJECTIVE: To evaluate upper extremity functional capacity and ADL in patients with HF and compare them with healthy controls.
    METHODS: This study included 30 HF patients and healthy controls. Upper extremity functional capacity was assessed with the 6-Minute Pegboard Ring Test (6PBRT), ADL by the Londrina protocol, exercise capacity by 6-Minute Walk Test (6MWT), peripheral muscle strength by hand dynamometer, and dyspnea by Modified Medical Research Council Scale (MMRC). For performance tests, pre-test (resting) and post-test (after performance) values ​​were also measured.
    RESULTS: Patients with HF with ejection fraction ≤50 % and controls were similar in terms of age (52.63±6.2 and 50.03±6.5 years, respectively) and gender (25 females for each group) (p > 0.05). Patients showed a statistically significant increase in total test time in the Londrina protocol and fewer rings moved in 6PBRT (p < 0.0001). The post-test dyspnea (p = 0.03) and pre-test arm fatigue (p < 0.0001) were observed to be higher in patients in the Londrina protocol. There was a statistically significant group by time interaction in the patients\' pre- and post-test lower heart rate (F= 4.80, p = 0.03), post-test dyspnea (p < 0.0001), and post-test arm fatigue (p = 0.005) were observed to be higher in patients in 6PBRT.
    CONCLUSIONS: The evidence showed a decrease in upper extremity functional capacity in patients with HF. Patients required more time to perform their ADLs compared with healthy controls.
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  • 文章类型: Journal Article
    脑瘫是影响中枢神经系统并导致严重残疾的最常见疾病。
    确定触摸屏平板电脑对偏瘫儿童精细运动功能的影响。
    这是一项涉及60名儿童的随机对照试验,年龄从5岁到7岁,随机分为两组:干预组或对照组(每组30名儿童)。两组均连续12周进行设计的精细运动任务。此外,三十分钟,干预组患者在触摸屏平板电脑上进行精细运动锻炼.上肢功能,使用上肢技能测试(QUEST)的质量,在推荐的治疗方案前后测量手指的灵活性和捏力,九孔销钉测试和Jamar液压夹钳,分别。
    入院时干预组之间的所有结局指标相当(P>0.05)。两组中所有评估变量均有显着改善。同时,干预组手指灵巧度改善明显高于对照组(P<0.05),夹紧强度,与对照组相比,上肢功能。
    包括带有专门设计的精细运动程序的触摸屏智能平板电脑应用程序是一种有效的方法,可帮助患有U-CP的儿童更有效地发挥其精细运动技能。
    UNASSIGNED: Cerebral palsy is the most frequent condition affecting the central nervous system and causing large disability.
    UNASSIGNED: To determine the impact of touch screen tablet upon fine motor functions in children with hemiparesis.
    UNASSIGNED: This was a randomized controlled trial involving 60 children, ranging in age from 5 to 7 years old, randomized into two groups: intervention or control group (30 children per group). Both groups were given 12 consecutive weeks of designed fine motor tasks. Additionally, for thirty minutes, the intervention group was given a fine motor exercise program on a touch screen tablet. Upper limb function, finger dexterity and pinch strength were measured pre and post the recommended treatment program using the quality of upper extremity skill test (QUEST), Nine-Hole Peg Test and Jamar hydraulic pinch gauge, respectively.
    UNASSIGNED: All outcome measures were equivalent between intervention groups at admission (P > 0.05). Significant improvements were found in all assessed variables within the two groups. Meanwhile, the intervention group had significantly higher improvements (P < 0.05) in finger dexterity, pinch strength, and upper limb function when compared with the control groups.
    UNASSIGNED: Including a touch screen smart tablet application with a specially designed fine motor program is an effective method that helps children with U-CP perform more effectively with their fine motor skills.
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  • 文章类型: Journal Article
    背景:患有帕金森病(PwPD)的人表现出运动改变,这可能会影响需要运动速度和/或准确性的日常生活任务。
    目的:NCT01439022的子分析,旨在估计两种不同的运动训练方案(全局和手写上肢运动训练)对反应时间的影响程度,行进速度,和PwPD的准确性。
    方法:70个PwPD,右侧优势人群以1:1的比例随机分为两个6个月训练方案组;35例PwPD进行了全局运动训练,35例进行了特定训练(手写上肢运动).在基线时对速度-准确性和权衡进行了评估,经过3个月和6个月的培训,在12个月的随访中。本研究使用了先前发表的随机对照试验的数据,该试验包括PwPD的6个月自我管理的社区锻炼计划。对于本研究,我们仅包括在基线评估期间完成Fitts任务的参与者。
    结果:在上肢评估中,没有发现触摸次数的主要影响,但是锻炼组的左侧显示出随着时间的推移略有增加。从基线到6个月和12个月,运动组左侧的误差平均值显着降低。运动组的误差CoV较低,反应时间CoV在右侧增加。左侧Fittsr的重要发现表明运动组的值较低,改善持续12个月。
    结论:我们报告了全球运动干预措施在改善反应时间和旅行速度方面的潜力,以及其他电机控制指标,在12个月时产生持久影响,特别是在非主导方面。
    BACKGROUND: People with Parkinson\'s disease (PwPD) present motor alterations which can impact daily life tasks that require speed and/or accuracy of movement.
    OBJECTIVE: A sub analysis of NCT01439022, aiming to estimate the extent to which two different exercise training protocols (global and handwriting upper limb exercise training) impact reaction time, travel speed, and accuracy in PwPD.
    METHODS: Seventy PwPD, right-side dominant were randomised 1:1 into two six-month training protocol groups; 35 PwPD performed global exercise training and 35 performed specific training (handwriting upper limb exercise movements). Assessments of speed-accuracy and trade-off were carried out at baseline, after 3 and 6 months of training, and at a 12-month follow-up. The current study used data from a previous publication of a randomised controlled trial that included a 6-month self-managed community exercise programme for PwPD. For the present study we included only the participants who completed the Fitts\' task during the baseline assessment.
    RESULTS: In the upper limb assessments, no main effects were found for the number of touches, but the exercise group showed a marginal increase over time on the left side. Error averages on the left side decreased significantly for the exercise group from baseline to 6 and 12 months. The exercise group also presented a lower Error CoV and the Reaction Time CoV increased on the right side. Significant findings for Fitts r on the left side indicated lower values for the exercise group, with improvements continuing at 12 months.
    CONCLUSIONS: We report the potential of global exercise interventions to facilitate improvements in reaction time and travel speed, as well as other motor control metrics, with lasting effects at 12 months, particularly on the non-dominant side.
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  • 文章类型: Journal Article
    背景与目的:肩袖肌腱炎(RCT)是最常见的肩关节病变之一。它引起疼痛,限制肩关节运动,并损害功能。尽管有各种治疗方法,目前尚无关于RCT最有效干预措施的具体指南.据我们所知,没有研究比较Kinesio录音(KT)和冷疗(CT)对RCT患者的影响。为此,本研究旨在探讨和比较KT和CT对RCT患者疼痛缓解和上肢功能的短期影响.材料和方法:评估了114人的资格。符合纳入标准并同意参与的52名RCT患者被随机分配到KT或CT组。为所有参与者提供了标准化的家庭锻炼计划。他们的疼痛强度,上肢功能,肩部运动范围(ROM),在KT或CT应用三天后,对握力和握力进行了评估。结果:KT组各项评估值均显著提高。在CT组中,与初始值相比,在应用的第三天结束时,CT组的疼痛评分(活动期间的数字评定量表(NRS)疼痛评分除外)显着改善(p<0.05)。对于所有的测量结果,时间×组交互作用的影响有统计学意义(p<0.05)有利于KT组,除了静息疼痛(p=0.688)。结论:研究结果表明,KT和CT可作为RCT患者休息和夜间疼痛缓解的辅助运动方式。KT对活动性疼痛也有积极作用,函数,ROM,和握力。与使用CT来改善夜间疼痛相比,使用KT和锻炼计划可能是更有效的治疗选择,活动性疼痛,RCT患者短期康复过程中的上肢功能。
    Background and Objectives: Rotator cuff tendonitis (RCT) is one of the most common shoulder pathologies. It causes pain, limits shoulder joint movements, and impairs function. Despite various treatment methods, there are currently no specific guidelines regarding the most effective intervention for RCT. To the best of our knowledge, no studies have compared the effects of Kinesio taping (KT) and cold therapy (CT) on individuals with RCT. To this end, this study aimed to investigate and compare the short-term effects of KT and CT on pain relief and upper extremity functionality in individuals with RCT. Materials and Methods: One hundred and fourteen individuals were assessed for eligibility. Fifty-two individuals with RCT who met the inclusion criteria and agreed to participate were randomly allocated into either the KT or the CT group. A standardized home exercise program was given to all the participants. Their pain intensity, upper extremity function, shoulder range of motion (ROM), and grip strength were evaluated initially and after the three days of KT or CT applications. Results: All the assessment values significantly improved in the KT group. In the CT group, only the pain scores (except for the numerical rating scale (NRS) pain score during activity) were significantly improved in the CT group at the end of the third day of application compared to the initial values (p < 0.05). For all the measurement outcomes, the effects of time × group interactions were statistically significant (p < 0.05) in favor of the KT group, except for the resting pain (p = 0.688). Conclusions: The findings suggest that KT and CT could be used as adjunctive modalities to exercise for resting and night pain relief in patients with RCT. KT also had positive effects on the activity pain, function, ROM, and grip strength. The use of KT along with an exercise program could be a more effective therapeutic choice than the use of CT for improving night pain, activity pain, and upper extremity function during the short-term rehabilitation of RCT patients.
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  • 文章类型: Journal Article
    背景:心脏直视手术,涉及正中胸骨切开术,术后早期可能导致胸壁运动减弱和肺功能受限。通常建议在手术后进行胸部和上肢运动范围(ROM)锻炼,但尚未评估对肺容量和氧合的影响。这项研究的目的是评估上肢抬高的即时效果,有或没有同时深呼吸,心脏手术后的肺功能。
    方法:在一项随机的2×2交叉试验中,2022年春季,厄勒布罗大学医院在手术后的第一天对22名成年患者(>18岁)进行了评估,瑞典。涉及五个双侧上肢抬高的练习,同时进行深呼吸(ROM-DB)或不进行深呼吸(ROM),当直立坐在床边时,进行了评估。外周血氧饱和度(Rad-5v;Masimo,Irvine,美国)是主要结果。在运动过程中连续记录潮气量和呼吸频率(Spiropalm;Cosmed,罗马,意大利)。心率,疼痛,运动前后评估劳累和呼吸困难。
    结果:ROM-DB和ROM都暂时增加了外周血氧饱和度(分别为+1%±1,p=0.004和+1%±1,p<0.001),这些练习之间没有显着差异(p=0.525)。与ROM相比,ROM-DB显着增加了VT(798±316与602毫升±176,p=0.004)。然而,ROM-DB引起更明显的疼痛(p=0.012),劳力(p=0.035)和呼吸困难(p=0.013)比ROM。
    结论:上肢抬高可瞬间改善氧合,都是在有和没有同时深呼吸的情况下进行的,这些练习之间没有显着差异。与仅上肢抬高相比,加性深呼吸改善了潮气量,但引起了更多的疼痛,运动期间的劳累和呼吸困难。
    背景:ClinicalTrials.gov(NCT05278819)。
    BACKGROUND: Open heart surgery, involving median sternotomy, may cause diminished chest wall motion and restrictive pulmonary function in the early postoperative period. Thoracic and upper extremity range of motion (ROM) exercises are often recommended after surgery but have not been evaluated regarding effect on lung volumes and oxygenation. The objective of this study was to evaluate the immediate effect of upper limb elevations, with or without simultaneous deep breathing, on lung function after cardiac surgery.
    METHODS: In a randomized 2 × 2 crossover trial, 22 adult patients (> 18 years old) were assessed during one of the first days after surgery in the spring of 2022 at Örebro University Hospital, Sweden. Exercises involving five bilateral upper limb elevations, performed either with simultaneous deep breathing (ROM-DB) or without (ROM), while sitting in an upright position at the edge of the bed, were evaluated. Peripheral oxygen saturation (Rad-5v; Masimo, Irvine, USA) was the primary outcome. Tidal volume and respiratory rate were recorded continuously during the exercises (Spiropalm; Cosmed, Rome, Italy). Heart rate, pain, exertion and dyspnoea were evaluated before and after the exercises.
    RESULTS: Both ROM-DB and ROM momentarily increased peripheral oxygen saturation (+ 1% ± 1, p = 0.004 and + 1% ± 1, p < 0.001, respectively), with no significant differences between these exercises (p = 0.525). ROM-DB significantly increased the VT compared with ROM (798 ± 316 vs. 602 mL ± 176, p = 0.004). However, ROM-DB induced more pronounced pain (p = 0.012), exertion (p = 0.035) and dyspnoea (p = 0.013) than ROM.
    CONCLUSIONS: Upper limb elevations improved oxygenation momentarily, both performed with and without simultaneous deep breathing, with no significant differences between these exercises. The additive deep breathing improved tidal volume compared with upper limb elevations alone, but induced more pain, exertion and dyspnoea during the performance of exercise.
    BACKGROUND: ClinicalTrials.gov (NCT05278819).
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    用于上肢神经康复的机器人设备允许增加练习强度,通常依靠基于视频游戏的培训策略,而个性化培训和整合功能培训的能力有限。这项研究显示了机器人任务特定培训(TST)协议的开发并评估了所达到的剂量。
    混合方法研究。用于上肢的3D机器人设备,提供给治疗师在神经康复期间使用。第一阶段允许临床医生为TST定义专用会话协议。在第二阶段中,应用方案并测量所达到的剂量。
    第一阶段(N=5):特定协议,使用减重进行评估,其次是定制的被动运动,然后发展主动运动实践。第二阶段:协议成功应用于所有参与者(N=10)。干预时间:4.5±0.8周,会议频率:1.4±0.2次/周,会话长度:42±9分钟,会话密度:39±13%,强度:214±84运动/会话,难度:dn=0.77±0.1(归一化到达距离)和=6.3±23°(横向到达角度)。参与者的会议密度和强度是一致的,但观察到明显的难度差异。在干预期间没有观察到指标的变化。
    机器人系统可以通过根据参与者的需求和能力调节练习难度来支持具有高治疗强度的TST。
    很少有机器人设备允许中风后上肢的任务特定训练(TST)。机器人TST在临床医生监督的环境中被证明是可行的。在有监督的机器人TST会话中,临床医生可以调节任务难度,同时保持相似的会议密度和强度,以适应患者的损伤。机器人TST可用于上肢神经康复,而不会影响训练强度。
    UNASSIGNED: Robotic devices for upper-limb neurorehabilitation allow an increase in intensity of practice, often relying on video game-based training strategies with limited capacity to individualise training and integrate functional training. This study shows the development of a robotic Task Specific Training (TST) protocol and evaluate the achieved dose.
    UNASSIGNED: Mixed-method study. A 3D robotic device for the upper limb, was made available to therapists for use during neurorehabilitation sessions. A first phase allowed clinicians to define a dedicated session protocol for TST. In a second phase the protocol was applied and the achieved dose was measured.
    UNASSIGNED: First phase (N = 5): a specific protocol, using deweighting for assessment, followed by customised passive movements and then active movement practice was developed. Second phase: the protocol was successfully applied with all participants (N = 10). Intervention duration: 4.5 ± 0.8 weeks, session frequency: 1.4 ± 0.2sessions/week, session length: 42 ± 9mins, session density: 39 ± 13%, intensity: 214 ± 84 movements/session, difficulty: dn = 0.77 ± 0.1 (normalised reaching distance) and Ɵ = 6.3 ± 23° (transverse reaching angle). Sessions\' density and intensity were consistent across participants but clear differences of difficulty were observed. No changes in metrics were observed over the intervention.
    UNASSIGNED: Robotic systems can support TST with high therapy intensity by modulating the practice difficulty to participants\' needs and capabilities.
    Few robotics devices allow for Task Specific Training (TST) of the upper-limb post stroke.Robotic TST was shown to be feasible in a clinicians supervised setting.In supervised robotic TST sessions, clinicians can modulate task difficulty while preserving similar sessions’ density and intensity to adjust to the patient impairment.Robotic TST might be used for upper-limb neurorehabilitation without compromising the training intensity.
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  • 文章类型: Journal Article
    目的:骨关节炎(OA)是一种常见的退行性关节疾病,对生活质量有显著影响,特别是在影响手时。然而,OA患者是否与发展上肢疾病的高风险相关,特别是触发手指(TF)和腕管综合征(CTS),尚不清楚。本研究旨在评估OA患者上肢疾病的风险。
    方法:使用美国协作网络,TriNetX研究网络的一个子集,我们确定了诊断为OA的患者,并根据倾向评分将他们与非OA对照1:1进行匹配.匹配的协变量包括年龄,性别,种族,和合并症。该队列由每组1,554,182名患者组成。TF和CTS的危险比,以及相关的外科手术,在5年的随访期内进行评估。
    结果:与对照组相比,OA患者的TF风险增加1.30倍[95%置信区间(CI)=1.27-1.33],CTS风险增加1.50倍(95CI=1.48-1.53)。接受手术干预的风险比TF为1.61(95CI=1.51-1.71),CTS为1.97(95CI=1.78-2.19)。在根据年龄和性别进行的各种敏感性分析和分层中,这些风险仍然很重要。
    结论:OA显著增加TF和CTS的风险。这些发现强调了对OA患者上肢疾病的警惕监测和管理的必要性,以改善患者的整体护理和预后。未来的研究有必要关注OA的病理机制及其对上肢健康的影响,以制定有针对性的干预措施。
    OBJECTIVE: Osteoarthritis (OA) is a prevalent degenerative joint disease that significantly impacts quality of life, particularly when affecting the hands. However, whether patients with OA are associated with higher risk of developing upper limb disorders, specifically trigger finger (TF) and carpal tunnel syndrome (CTS), remains unclear. This study aimed to evaluate the risk of upper limb disease in OA patients.
    METHODS: Using the US Collaborative Network, a subset of the TriNetX research network, we identified patients diagnosed with OA and matched them 1:1 with non-OA controls based on propensity scores. Matching covariates included age, sex, race, and comorbidities. The cohort consisted of 1,554,182 patients in each group. The hazard ratio of TF and CTS, as well as related surgical interventions, was assessed over a 5-year follow-up period.
    RESULTS: Patients with OA had a 1.30-fold increased risk of TF [95% confidence interval (CI)=1.27-1.33] and a 1.50-fold increased risk of CTS (95%CI=1.48-1.53) compared to controls. The hazard ratios for undergoing surgical interventions were 1.61 for TF (95%CI=1.51-1.71) and 1.97 for CTS (95%CI=1.78-2.19). These risks remained significant across various sensitivity analyses and stratifications according to age and sex.
    CONCLUSIONS: OA significantly increases the risk of TF and CTS. These findings highlight the need for vigilant monitoring and management of upper limb disorders in OA patients to improve overall patient care and outcomes. Future research is warranted to focus on pathological mechanisms of OA and their impact on upper limb health to develop targeted interventions.
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