Undescended testes

未降睾丸
  • 文章类型: Journal Article
    腹腔镜探查目前被认为是管理无法触及的腹内睾丸的金标准。在Fowler-Stephen(FS)技术中,通过分割睾丸血管来解决血管蒂短的问题,在Shehata技术(ST)中,通过牵引睾丸血管来解决。儿科外科医生在选择一种技术而不是另一种技术方面缺乏共识。该分析比较了ST分期腹腔镜睾丸固定术与经过时间测试的FS技术在管理高腹下睾丸中的报告结果。
    本系统评价和荟萃分析按照系统评价和荟萃分析指南的首选报告项目进行。仅包括随机对照试验和比较研究。比较的主要结果是睾丸萎缩的发生率,睾丸回缩/上升率,I期和II期睾丸固定术的手术时间。
    本分析基于三项随机研究,在117例符合纳入标准的患者中,共119例未降睾丸。I期FS技术的手术时间较短;然而,在II期腹腔镜睾丸固定术中,两种手术的手术时间无统计学差异.干预后睾丸萎缩的汇总分析,睾丸回缩率,和术后住院时间显示两种手术之间没有差异。
    FS和STs在干预后睾丸萎缩方面具有可比性,睾丸收缩/上升;然而,在I期腹腔镜睾丸固定术中,使用FS技术的平均手术时间明显减少。
    UNASSIGNED: Laparoscopic exploration is currently considered the gold standard for managing nonpalpable intraabdominal testes. The problem of short vascular pedicle is addressed in Fowler-Stephen (FS) technique by the division of testicular vessels and in Shehata technique (ST) by traction on testicular vessels. There is a lack of the consensus among pediatric surgeons on the choice of one technique over other. This analysis compares the reported outcomes of staged laparoscopic orchidopexy by ST with the time tested FS technique in managing high intraabdominal undescended testis.
    UNASSIGNED: The present systematic review and meta-analysis was conducted as per the preferred reporting items for the systematic review and meta-analyses guidelines. Only randomized controlled trials and comparative studies were included. The primary outcomes compared were the incidence of testicular atrophy, testicular retraction/ascent rate, and operative time of Stage I and Stage II orchidopexy.
    UNASSIGNED: The present analysis was based on three randomized studies with a total of 119 undescended testes in 117 patients satisfying the inclusion criteria. The operative time was less in Stage I FS technique; however, there was no statistically significant difference in operative time of both procedures during the Stage II laparoscopic orchidopexy. Pooled analysis of postintervention testicular atrophy, testicular retraction rate, and duration of postoperative hospitalization showed no difference between both procedures.
    UNASSIGNED: Both FS and STs are comparable in terms of postintervention testicular atrophy, testicular retraction/ascent; however, the mean operative time is significantly less with FS technique in Stage I laparoscopic orchidopexy.
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  • 文章类型: Systematic Review
    UNASSIGNED:要比较安全性,功效,单切口阴囊睾丸固定术(SISO)和传统双切口腹股沟睾丸固定术(TTIO)治疗儿童原发性可触及未降睾丸(PUDT)的美容结果。
    UNASSIGNED:对PubMed上发表的所有相关研究进行系统的文献检索,Embase,Medline,科克伦图书馆,WebofScience数据库,和万方数据直到2021年7月进行。手术时间,住院时间,转化率,伤口感染或裂开,阴囊血肿或肿胀,睾丸萎缩,重新思考,疝或鞘膜积液,需要镇痛药,使用Mantel-Haenszel或逆方差方法比较SISO和TTIO之间的美容结果。
    UNASSIGNED:最终分析共纳入17项研究,涉及2,627名儿童(1,362SISO和1,265TTIO)。SISO的转化率为3.6%。对于PUDT,SISO方法的手术时间比TTIO方法的手术时间有统计学意义(加权平均差-11.96,95%置信区间-14.33至-9.59,I2=79%,P<0.00001)和较短的住院时间(加权平均差-1.05,95%置信区间-2.07至-0.03,P=0.04)。SISO需要更少的镇痛药,并且比TTIO具有更好的美容效果。SISO的总数相似,短期,或长期并发症发生率与TTIO。
    UNASSIGNED:与TTIO相比,SISO具有手术时间短的优点,住院时间较短,术后疼痛减少,和更好的化妆品吸引人的结果。SISO是一个保险箱,有效,有希望的,和潜在的PUDT微创手术方法。在选定的隐睾患者中,SISO是TTIO的替代品,尤其是位置较低的。
    UNASSIGNED:https://www。crd.约克。AC.英国/PROSPERO/,标识符:CRD42021268562。
    UNASSIGNED: To compare the safety, efficacy, and cosmetic results of single-incision scrotal orchiopexy (SISO) and traditional two-incision inguinal orchiopexy (TTIO) for primary palpable undescended testes (PUDTs) in children.
    UNASSIGNED: A systematic literature search of all relevant studies published on PubMed, Embase, Medline, Cochrane Library, Web of Science database, and Wanfang data until July 2021 was conducted. The operative time, hospitalization duration, conversion rate, wound infection or dehiscence, scrotal hematoma or swelling, testicular atrophy, reascent, hernia or hydrocele, analgesics needs, and cosmetic results were compared between SISO and TTIO using the Mantel-Haenszel or inverse-variance method.
    UNASSIGNED: A total of 17 studies involving 2,627 children (1,362 SISOs and 1,265 TTIOs) were included in the final analysis. The conversion rate of SISO was 3.6%. The SISO approach had a statistically significant shorter operative time than the TTIO approach for PUDT (weighted mean difference-11.96, 95% confidence interval -14.33 to -9.59, I2 = 79%, P < 0.00001) and a shorter hospital stay (weighted mean difference-1.05, 95% confidence interval -2.07 to -0.03, P = 0.04). SISO needed fewer analgesics and had better cosmetic results than TTIO. SISO had a similar total, short-term, or long-term complication rate with TTIO.
    UNASSIGNED: Compared with TTIO, SISO has the advantages of shorter operative time, shorter hospitalization duration, less postoperative pain, and better cosmetic appealing results. SISO is a safe, effective, promising, and potential minimal invasive surgical approach for PUDT. SISO is an alternative to TTIO in selected cryptorchid patients, especially for lower positioned ones.
    UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42021268562.
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  • 文章类型: Journal Article
    BACKGROUND: Traditional open orchiopexy is still a standard of treatment for palpable undescended testicles. Recently several authors reported successful results using a laparoscopic approach in the treatment of palpable cryptorchidism. The present systematic review and meta-analysis investigated the utility of laparoscopic orchiopexy for palpable cryptorchidism.
    METHODS: Scientific databases (PubMed, Scopus, Web of Science, and EMBASE) were systematically searched for relevant articles using the following terms: (palpable cryptorchidism or palpable undescended testes) AND (laparoscopic orchiopexy or laparoscopic orchiopexy). The inclusion criteria were all children with unilateral or bilateral palpable undescended testes who underwent laparoscopic orchiopexy (LO) compared to children who underwent conventional open orchiopexy (CO). The main outcomes were the proportion of children requiring redo-orchiopexy and the incidence of postoperative complications. Secondary outcomes were duration and the cost of surgery.
    RESULTS: The final meta-analysis included five studies involving 705 children; LO, n = 369 (52.3%) and CO, n = 336 (47.7%). The majority of the included patients had unilateral palpable cryptorchidism. No significant differences were found in regard to average age at the time of surgery and follow-up periods between the investigated groups. No statistically significant differences were found in regard to redo-orchiopexy rates (RR = 0.22, 95% CI 0.03-1.88, p = 0.17), early complications (RR = 0.66, 95% CI 0.21-2.08, p = 0.48) and incidence of testicular atrophy (RR = 0.36, 95% CI 0.03-3.88, p = 0.40). No significant differences in the operative duration were observed among the groups. Laparoscopy was associated with higher costs in most of the studies.
    CONCLUSIONS: LO is safe and effective in children with palpable cryptorchidism. The rates of redo-orchiopexy as well as an incidence of early complications and testicular atrophy rates are comparable to CO.
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  • 文章类型: Case Reports
    耻骨发育不全是一种罕见的发现,被诊断为偶然发现或与各种临床综合征有关。它通常在儿童早期发现,然而,很少有报道在成年后发现的病例。我们介绍了一例64岁男性单侧耻骨上肌发育不全,在持续创伤的检查中偶然发现的。我们的患者在童年时期就报告了单侧髋关节脱位的治疗方法,并且有同侧睾丸未降的手术史。这个确切的耻骨rami发育不全的星座,睾丸未降和髋关节发育不良在现有文献中是独一无二的。尽管我们的病人生活正常,耻骨发育不全是偶然发现的,始终评估这些患者的全身受累情况是很重要的,来自肌肉骨骼系统或其他器官,以便为他们提供更好的治疗。
    Pubic bone aplasia is a rare finding that is either diagnosed as incidental finding or associated with various clinical syndromes. It is usually discovered in early childhood, however, there are few reported cases of late discovery during adulthood. We present a case of a 64-year-old male with unilateral superior pubic rami aplasia, discovered incidentally during workup for sustained trauma. Our patient reported treatment for unilateral hip dislocation in his early childhood and had a history of operated undescended testes ipsilaterally. This exact constellation of pubic rami aplasia, undescended testes and hip dysplasia is unique in the available literature. Even though our patient had a normal life and the pubic aplasia was discovered incidentally, it is important to always assess these patients for systemic involvement, either from the musculoskeletal system or other organs, in order to provide better treatment for them.
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  • 文章类型: Case Reports
    Transverse testicular ectopia (TTE) is an uncommon anatomical abnormality where both the gonads migrate toward the same hemiscrotum. Embryologically, several theories regarding the origin of TTE have been suggested including adhesion and fusion of developing Wolffian canals, aberrant gubernaculum, testicular adhesions, defective formation of the internal inguinal ring, and traction on the testis by persistent Mullerian structures. To date, about 100 cases of TTE have been reported in the literature. Herein, we report five cases of TTE operated in the Department of Paediatric Surgery, Sardar Patel Medical College, Bikaner, over a period of 5 years. All cases were in the age group of 3 months to 4 years, out of which four were diagnosed preoperatively by clinical examination and ultrasonography (USG). Two of these four cases presented with inguinoscrotal swellings and contralateral undescended testes and other two presented with absence of testes in the scrotum. One case presented with a scrotal abscess which revealed both the testes in the abscess cavity. All five cases were operated upon with herniotomy and transseptal orchidopexy and discharged successfully. TTE, although rare, has a spectrum of presentations and should be kept in mind as a possibility in cases of inguinoscrotal disorders in young age group. A preoperative USG may be helpful in conformation of diagnosis.
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  • 文章类型: Journal Article
    目的:对于高度腹内睾丸的隐睾患者的最佳手术策略尚未达成共识。这项系统评价和荟萃分析比较了Fowler-Stephens睾丸固定术(FSO)的1期或2期结果,开放或腹腔镜。
    方法:数据库PubMed,科克伦图书馆,WebofScience数据库,俄罗斯科学引文索引,SciELO引文索引,中国国家知识基础设施,万方数据,系统检索了《中国生物》中有关文献。
    结果:最终分析中包括了涉及1991年手术睾丸的60项研究。1期和2期FSO的总体成功率分别为85%和87%,两者的总体萎缩率分别为10%。1阶段FSO的成功率,开放和腹腔镜,分别为83%和87%;萎缩率为12%和8%。2期FSO的相应成功率分别为81%和89%;萎缩率分别为17%和8%。优势比表明2阶段FSO明显优于1阶段,腹腔镜优于开腹。随着时间的推移评估腹腔镜FSO,2000年之前、2000年至2010年以及2010年之后的成功率为85%,89%,88%,萎缩率为15%,9%,6%,报告中没有异质性,漏斗图显示无发表偏倚。
    结论:每种矫正高位腹内睾丸(IAT)的手术方法均具有可接受的成功率,从81%到89%。然而,成功率最高,萎缩率最低,2期腹腔镜FSO是治疗腹内隐睾的首选方法。
    OBJECTIVE: There has been no consensus regarding the best surgical strategy for patients with cryptorchidism involving high-level intra-abdominal testes. This systematic review and meta-analysis compared the outcomes of Fowler-Stephens orchiopexy (FSO) conducted as 1-stage or 2-stage, open or laparoscopic.
    METHODS: The databases PubMed, Cochrane Library, Web of Science Database, Russian Science Citation Index, SciELO Citation Index, China National Knowledge Infrastructure, WanFang Data, and China Biology Medical disc were systematically searched for relevant articles.
    RESULTS: Sixty studies involving 1991 operated testes were included in the final analysis. The overall success rates for 1- and 2-stage FSOs were 85% and 87%, respectively; overall atrophy rates for both were 10%. The success rates of 1-stage FSOs, open and laparoscopic, were 83% and 87%; with atrophy rates of 12% and 8%. The corresponding success rates of 2-stage FSOs were 81% and 89%; with atrophy rates of 17% and 8%. The odds ratios indicated that 2-stage FSO was significantly superior to 1-stage, and laparoscopic superior to open. Evaluating laparoscopic FSO over time, the success rates prior to year 2000, 2000 through 2010, and after 2010 were 85%, 89%, and 88%, and atrophy rates were 15%, 9%, and 6%, with no heterogeneity in the reports, and the funnel plot showed no publication bias.
    CONCLUSIONS: Each surgical technique for correcting high-level intra-abdominal testes (IATs) had an acceptable success rate, from 81% to 89%. However, in terms of highest success rate and lowest atrophy rate, 2-stage laparoscopic FSO is the first choice for treating high intra-abdominal cryptorchidism.
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  • 文章类型: Journal Article
    OBJECTIVE: Limited efforts have been made in assessing the qualities of clinical practice guidelines (CPGs) on cryptorchidism (UDT). This appraisal aims to determine the quality of recent CPGs on the management of UDT.
    METHODS: After systematic literature search, all English-based CPGs providing recommendations for the management of UDT from 2012 to 2017 were reviewed. Using the AGREE II (Appraisal of Guidelines and Research Evaluation) instrument, eligible CPGs were independently appraised by 5 reviewers. Domain scores were calculated and summarized. Intraclass coefficient (ICC) was used to assess for interrater reliability.
    RESULTS: Five CPGs from Agency for Healthcare Research and Quality (AHRQ), American Urological Association (AUA), British Association of Pediatric Surgeons/British Association of Urologic Surgeons (BAPS/BAUS), Canadian Urological Association (CUA), and European Association of Urology/European Society for Pediatric Urology (EAU/ESPU) were assessed. There was a solid agreement (ICC: 0.749) among the 5 reviewers (p<0.001). Most recommendations for diagnostic and treatment approaches were consistent across CPGs. For most guidelines, the domains of \'clarity of presentation,\' \'scope and purpose,\' \'stakeholder involvement,\' and \'rigor of development\' were high, while \'applicability\' was low.
    CONCLUSIONS: Most guidelines on UDT score high in the AGREE II domains and have consistent recommendations. To improve the \'applicability\' domain, future guidelines should improve on aspects that facilitate implementation of the recommendations.
    METHODS: Systematic review.
    METHODS: V (based on the lowest level of evidence utilized by the assessed guidelines).
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  • 文章类型: Journal Article
    未降睾丸(UDT)治疗的最佳模式仍存在争议。然而,从随机对照研究和荟萃分析中获得的知识使不同组的研究人员能够制定UDT患者管理指南.作者回顾了最近的文献,得出以下结论:(1)不推荐激素治疗,考虑到直接结果(只有15-20%的保留睾丸下降)和可能对精子发生的长期不利影响。(2)手术是首选的治疗方法;在大约95%的UDT中,睾丸固定术是成功的,并发症发生率低(约1%)。(3)Orchiopexy应在12至18月龄之间进行,或在第一次接触,如果诊断后。
    The best mode of undescended testis (UDT) treatment remains controversial. However, knowledge gained from randomized controlled studies and meta-analyses allowed different groups of researchers to set out guidelines on management of patients with UDT. The authors reviewed recent literature and came to the following conclusions: (1) Hormonal treatment is not recommended, considering both the immediate results (only 15-20% of retained testes descend) and the possible long-term adverse effects on spermatogenesis. (2) Surgery is the treatment of choice; orchiopexy is successful in about 95% of UDT, with a low rate of complications (about 1%). (3) Orchiopexy should be performed between 12 and 18 months of age, or at first contact if diagnosed later.
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  • 文章类型: Journal Article
    OBJECTIVE: To review the primary orchidopexy failure rate and outcome of repeat orchidopexy in a tertiary paediatric surgical centre and identify risk factors.
    METHODS: A prospectively collected and validated audits system was used to identify all boys having a repeat orchidopexy from August 1990 to December 2008 (18 years).
    RESULTS: In total, 1538 boys underwent orchidopexy with 1886 testicles operated on. Of these 348 (22.6%) patients had bilateral cryptorchidism. A need for repeat orchidopexy was identified in 31 boys resulting in a primary failure rate of 1.6% over the 18 years. Unilateral orchidopexy as the primary operation had a 1.5% failure rate. The failure rate for bilateral cryptorchidism was 1.87% per testicle rising to 1.93% per testicle when the primary operation was synchronous bilateral orchidopexy. Orchidopexy failure occurred in 9 patients (1.97%) who were under 24 months, 15 (2.67%) who were between 24 and 72 months and 7 (0.8%) over 72 months at time of first operation.
    CONCLUSIONS: Possible risk factors for primary orchidopexy failure are bilateral operation and older age at time of operation. Failure in achieving a satisfactory scrotal position (and testicular loss) following orchidopexy has been postulated as a potential surgical standard for revalidation of paediatric surgeons. This study adds important contemporary data to inform that process.
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