USA

美国
  • 文章类型: Journal Article
    胃癌是全球第五大最常见的癌症诊断和第四大癌症相关死亡原因。在美国,胃癌的发病率显示出明显的种族和种族差异,韩裔美国人的胃癌发病率比非西班牙裔白人高五倍以上。因为胃癌在美国并不常见,目前没有筛查指南。在胃癌发病率较高的国家,已经实施了早期发现和干预的筛查指南,这与降低死亡率相关.来自高发国家的移民一旦离开原籍国,就会以较低的速度发展成胃癌,但患胃癌的风险仍然较高。这种风险似乎随着后代的增加而降低。随着内窥镜检查的可用性增加,针对高危人群启动胃癌筛查指南有可能通过早期诊断和治疗胃癌来提高生存率.本文旨在为全球胃癌流行病学提供背景,回顾发展为胃癌的危险因素,突出美国胃癌负担中的种族和族裔差异,检查高发国家存在的现行指导方针,并建议未来的研究检查在高风险人群中额外筛查的有效性,以降低美国少数民族的胃癌死亡率和不同负担。
    Gastric cancer is the fifth most common cancer diagnosis and fourth leading cause of cancer-related death globally. The incidence of gastric cancer in the USA shows significant racial and ethnic disparities with gastric cancer incidence in Korean Americans being over five times higher than in non-Hispanic whites. Since gastric cancer is not common in the USA, there are no current screening guidelines. In countries with higher incidences of gastric cancer, screening guidelines have been implemented for early detection and intervention and this has been associated with a reduction in mortality. Immigrants from high incidence countries develop gastric cancer at lower rates once outside of their country of origin, but continue to be at higher risk for developing gastric cancer. This risk does seem to decrease with subsequent generations. With increasing availability of endoscopy, initiating gastric cancer screening guidelines for high-risk groups can have the potential to improve survival by diagnosing and treating gastric cancer at an earlier stage. This article aims to provide context to gastric cancer epidemiology globally, review risk factors for developing gastric cancer, highlight racial and ethnic disparities in gastric cancer burden in the USA, examine current guidelines that exist in high incidence countries, and suggest future studies examining the efficacy of additional screening in high-risk populations to reduce gastric cancer mortality and disparate burden on ethnic minorities in the USA.
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  • 文章类型: Journal Article
    本文简要介绍了公认共识标准的发展,美国医疗器械认可工作程序和认可共识标准概述,并分析了美国认可管理体系的经验,旨在为我国医疗器械标准管理体系的完善提供参考。
    This paper gives a brief introduction on the development of recognized consensus standards, the recognition working procedure and the overview of medical devices recognized consensus standards in USA, and analyzes the experience of the recognition management system in USA, aiming at providing a reference for the improvement of the medical device standard management system in China.
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  • 文章类型: Journal Article
    BACKGROUND: Because international guidelines recommend best practices regarding staging of incident bladder cancer, we determined the adherence to such recommendations in the United States, performing a large retrospective database analysis.
    METHODS: Patients with the diagnosis of urothelial cancer were identified in the Surveillance, Epidemiology, and End Results (SEER)-Medicare database between 1992 and 2007. Staging procedures were identified and analyzed. As reference for published recommendations, we used the American Urological Association (AUA), European Association of Urology (EAU), and National Comprehensive Cancer Network (NCCN) guidelines. Based on these sources, recommended initial staging of bladder cancer was analyzed. Of all 56,130 patients, 6148 (10.9%) had a cytologic examination, 29,677 (52.9%) had a standard urinalysis, 2882 (5.1%) underwent intravenous pyelography (IVP), 6950 (12.4%) underwent retrograde pyelography (RPG), and 8145 (14.5%) had computed tomography/magnetic resonance imaging (CT/MRI).
    RESULTS: There was a significant trend over the years to a higher use of cytologic analysis, standard urinalysis, and CT/MRI. We observed a significant trend toward a lower rate of IVP and a stable use of RPG. The limitation of our study is that claims data are designed for payment processing, not quality measurement.
    CONCLUSIONS: Despite published recommendations on the initial diagnosis of bladder cancer, our data show that less than half of the included patients received all the elements thought to be required for an initial diagnosis of bladder cancer as recommended by guidelines. Greater adherence to recommendations may ensure optimal treatment strategies. Appropriate treatment is critical to patient outcomes, because evidence-based therapeutic management can be practiced only if an accurate assessment of the disease takes place at the time of initial diagnosis.
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