目的:评价超声乳化白内障吸出术联合眼管成形术和小梁切开治疗原发性闭角型青光眼(PACG)的疗效。
方法:在本回顾性研究中,连续的,单外科医生病例系列,我们分析了接受手术的PACG患者的术前和术后测量结果.记录不良事件。主要结果是随访年每个四分位数的平均眼内压(IOP),以及每个四分位数结束时患者服用的降低IOP药物的数量与基线值相比。
结果:共纳入39例PACG患者的46只眼。术前眼压和青光眼药物治疗分别为19.33±6.03mmHg和1.80±1.39(N=46)。术后四个四分位数的IOP平均值(mmHg)为14.00±3.33(N=44),13.44±2.83(N=32),14.38±2.39(N=16),和14.92±2.90(N=13)(p<0.0001)。每个四分位数的平均用药数为0.32±0.80、0.22±0.42、0.59±0.80和0.08±0.28(p<0.0001),而所有四分位数的中位数为0。
结论:与基线测量相比,将OMNI手术系统与超声乳化术联合使用可显著降低平均IOP和降低IOP的药物数量。
OBJECTIVE: To evaluate the outcomes of combined canaloplasty and
trabeculotomy with phacoemulsification for primary angle-closure glaucoma (PACG).
METHODS: In this retrospective, consecutive, single-surgeon
case series, we analyzed the pre- and postoperative measurements of PACG patients who had the procedure. Adverse events were recorded. The main outcomes were mean intraocular pressure (IOP) in each quartile of the follow-up year and the number of IOP-lowering medications the patients were on by the end of each quartile compared to their baseline values.
RESULTS: A total of 46 eyes from 39 PACG patients were included. The preoperative IOP and glaucoma medications taken were 19.33±6.03 mm Hg and 1.80±1.39, respectively (N=46). Postoperative IOP means (mm Hg) in the subsequent four quartiles were 14.00±3.33 (N=44), 13.44±2.83 (N=32), 14.38±2.39 (N=16), and 14.92±2.90 (N=13) (p<0.0001). The mean number of meds was 0.32±0.80, 0.22±0.42, 0.59±0.80, and 0.08±0.28 in each respective quartile (p<0.0001), while the median was 0 across all quartiles.
CONCLUSIONS: Combining the OMNI surgical system with phacoemulsification led to substantial reductions in mean IOP and the number of IOP-lowering medications when compared to baseline measurements.