Poor removal of many pharmaceuticals and personal care products in sewage treatment plants leads to their discharge into the receiving waters, where they may cause negative effects for aquatic environment and organisms. In this study, electrochemical removal process has been used as alternative method for removal of mefenamic acid (MEF). For our knowledge, removal of MEF using electrochemical process has not been reported yet. Effects of initial concentration of mefenamic acid, sodium chloride (NaCl), and applied voltage were evaluated for improvement of the efficiency of electrochemical treatment process and to understand how much electric energy was consumed in this process. Removal percentage (R%) was ranged between 44 and 97%, depending on the operating parameters except for 0.1 g NaCl which was 9.1%. Consumption energy was 0.224 Wh/mg after 50 min at 2 mg/L of mefenamic acid, 0.5 g NaCl, and 5 V. High consumption energy (0.433 Wh/mg) was observed using high applied voltage of 7 V. Investigation and elucidation of the transformation products were provided by Bruker software dataAnalysis using liquid chromatography-time of flight mass spectrometry. Seven chlorinated and two non-chlorinated transformation products were investigated after 20 min of electrochemical treatment. However, all transformation products (TPs) were eliminated after 140 min. For the assessment of the toxicity, it was impacted by the formation of transformation products especially between 20 and 60 min then the inhibition percentage of E. coli bacteria was decreased after 80 min to be the lowest value.

With the aim of exploring treatment alternatives for priority insecticide acetamiprid (ACMP) abatement, the removal of this compound from water by ozonation was studied for the first time, paying special attention to the kinetic, mechanistic and toxicological aspects of the process. The second order rate constants of reactions between ACMP and both molecular ozone (O3) and hydroxyl radicals (OH) were determined to be 0.25M-1s-1 and 2.1·109M-1s-1, respectively. On the basis of kinetic results, the degradation of ACMP during ozonation could be well-explained by the reactivity of this pesticide with OH. HPLC/MS analysis of the ozonated ACMP showed ACMP-N-desmethyl, 6-chloronicotinic acid, N\'cyano-N-methyl acetamidine and N\'-cyano acetamidine as the major transformation products (TPs), all of them formed through amine α carbon oxidation in combination with hydrolysis. Microtox bioassays revealed an increase in the toxicity of the medium during ACMP ozonation process, followed by a decrease to relatively low values. These changes could be attributed to the synergistic effects between TPs as well as to the presence of toxic intermediate aldehydes. Even though adopting strategies to further promote ozone decomposition to hydroxyl radicals appears to be essential, ozonation can be an effective treatment process for ACMP removal and associated toxicity abatement.