背景:组织粘合剂已广泛用于眼科手术的各种手术,证明既有效又安全。然而,没有研究比较组织粘合剂-2-氰基丙烯酸正辛酯(SurgiSeal®)与传统缝合闭合术在接受下睑上睑手术的亚洲儿童中的手术疗效.方法:单中心回顾性病例对照研究。从2019年11月至2023年5月,对22例患者进行了手术矫正。共纳入20例随访至少1个月的患者进行分析。经过标准化的上睑手术,A组用表皮下缝合和2-氰基丙烯酸辛酯进行伤口闭合,B组用6-O快速吸收外科肠线缝合闭合。术后1、4、12周随访。结果:共10例(20只眼)行组织黏合剂皮肤闭合术(A组),10例患者(18眼)使用常规缝合材料进行了伤口闭合(B组)。性别比没有显着差异,手术时的平均年龄,术前和术后最佳矫正视力(BCVA),观察组间或平均手术时间。两组术后BCVA均有改善,症状缓解,术后角膜病变的严重程度显着降低。随访期间未报告复发或并发症。两组之间的美学结果相似,而组织粘合剂组儿童的护理人员对术后护理的便利性表示高度满意。结论:可以使用2-氰基丙烯酸辛酯(SurgiSeal®)成功闭合儿童下眼睑眼睑手术伤口。此方法简单,安全,与传统缝线相比有效。
Background: Tissue adhesive has been widely used in ophthalmic surgery for various procedures, proving both effective and safe. However, no studies have compared the surgical efficacy of the tissue adhesive 2-octyl cyanoacrylate (SurgiSeal®) to that of traditional suture closure in Asian children undergoing surgery for lower lid epiblepharon. Methods: This is a single-center retrospective
case-control study. Surgical correction for epiblepharon was performed on 22 patients from November 2019 to May 2023. A total of 20 patients who were followed up for at least 1 month were included for analysis. After standardized epiblepharon surgery, group A underwent wound closure with a subcuticular suture and 2-octyl cyanoacrylate, and group B underwent closure with a 6-O fast-absorbing surgical gut suture. Patients were followed up at 1, 4, and 12 weeks post-surgery. Results: A total of 10 patients (20 eyes) underwent skin closure with tissue adhesives (group A), and 10 patients (18 eyes) underwent wound closure using conventional suture material (group B). No significant differences in the sex ratio, mean age at operation, pre- and postoperative best-corrected visual acuity (BCVA), or average surgical time were observed between groups. Both groups exhibited improved postoperative BCVA, with symptom relief and a significant decrease in the severity of keratopathy after surgery. Neither recurrence nor complications were reported during follow-up. The aesthetic results were similar between groups, while caregivers of children in the tissue adhesive group expressed high satisfaction regarding the ease of postoperative care. Conclusions: Successful closure of lower lid epiblepharon surgery wounds in children can be performed using 2-octyl cyanoacrylate (SurgiSeal®). This method is simple, safe, and effective when compared to conventional sutures.