Teratomas

畸胎瘤
  • 文章类型: Journal Article
    宫颈畸胎瘤是新生儿畸胎瘤的一种罕见形式,是新生儿宫颈肿块的不寻常原因。畸胎瘤是来自所有3个生殖细胞层的不寻常肿瘤:内胚层,中胚层,和外胚层,比例不同。宫颈畸胎瘤是一种罕见的实体。其预后主要取决于新生儿呼吸窘迫的风险,它的延伸和潜在的恶性肿瘤。手术治疗必须尽可能完整,以避免复发和恶性转化。我们报告了一例完全切除和治愈的婴儿宫颈未成熟畸胎瘤。没有复发的报道。我们研究的目的是回顾诊断,先天性宫颈畸胎瘤的治疗和预后.宫颈畸胎瘤虽然不常见,但在新生儿颈部肿块的鉴别诊断中应考虑。畸胎瘤是源自所有三个生殖细胞层的罕见肿瘤,占所有病例的3%。先天性宫颈畸胎瘤的早期完整手术方法可以取得良好的效果,并发症和复发率低。
    Cervical teratoma is a rare form of teratoma in neonates and is an unusual cause of cervical masses in them. Teratomas are unusual tumors derived from all 3 germs cell layers: endoderm, mesoderm, and ectoderm, with varying proportions. The cervical teratoma is a rare entity. Its prognosis mostly depends on the risk of neonatal respiratory distress, its extension and potential malignancy. Surgical management must be as complete as possible to avoid recurrences and malignant transformation. We report a case of a cervical immature teratoma in an infant with total excision and cure. No recurrence has been reported. The aim of our study is to review the diagnosis, management and outcomes of congenital cervical teratomas. Cervical teratoma although uncommon should be considered in the differential diagnosis of neck masses in neonates. Teratomas are rare tumors derived from all three germ cell layers affecting the neck in 3% of all cases. An early complete surgical approach to congenital cervical teratomas allows good results with low rates of complication and recurrence.
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  • 文章类型: Case Reports
    卵巢类癌是一种罕见的肿瘤,其中甲状腺(甲状腺肿)和类癌成分共存。该疾病通常被认为是边缘性恶性肿瘤,然而,已经描述了转移性疾病的病例。文献中没有数据可用于指导诊断和治疗。
    我们使用以下关键词对文献中发表的组织病理学证实的类癌病例进行了汇总分析和系统评价:“卵巢类癌”,“胸膜类癌病例报告”。在SpedaliCivili的肿瘤内科病房诊断并随访了一例树状类癌肿瘤(布雷西亚,意大利)也被描述和包括在内。
    确定了66篇合格出版物,提供来自117名患者的数据,加上我们机构确诊的病例.在介绍时,在88名有症状的患者中,37%的患者患有腹胀,49%的患者因腹部肿瘤肿块增大而疼痛,37%来自便秘(仅在其中9个中分析了肽YY,导致高于生理范围)。手术是99%患者的主要治疗方法。3例患者在诊断时患有转移性疾病,5例患者在根治性手术后复发。疾病复发时的组织学与两名患者的甲状腺成分有关,两名患者的类癌成分,一名患者的两种组织学。未达到该系列中的中位无病生存期和总生存期。
    卵巢类癌通常表现为良性行为,手术在大多数情况下是治愈性的。然而,由于甲状腺和神经内分泌(类癌)成分,一小部分患有这种疾病的患者可能会复发。因此,需要对彻底手术的患者进行随访,特别是那些在诊断时患有大量疾病的人。
    Ovarian strumal carcinoid is a rare tumor in which thyroid (struma) and carcinoid components coexist. The disease is generally considered to be a borderline malignancy, however, cases with metastatic disease have been described. No data in the literature are available to guide diagnosis and therapy.
    We performed a pooled analysis and a systematic review of histopathological-confirmed strumal carcinoid cases published in the literature using the following keywords: \"strumal carcinoid of the ovary\", \"strumal carcinoid case report\". A case of strumal carcinoid tumor diagnosed and followed-up at the Medical Oncology Unit of Spedali Civili (Brescia, Italy) was also described and included.
    Sixty-six eligible publications were identified, providing data from one hundred and seventeen patients, plus a case diagnosed at our institution. At presentation, among the eighty-eight patients with symptomatic disease, 37% of patients suffered from abdominal distention and 49% from pain due to a growing abdominal tumor mass, 37% from constipation (peptide YY was analyzed in only nine of them, resulting above the physiologic range). Surgery was the primary therapy in 99% of the patients. Three patients had metastatic disease at diagnosis and five patients underwent recurrence after radical surgery. Histology at disease recurrence concerned the thyroid component in two patients, the carcinoid component in two patients, both histologies in one patient. Median disease-free survival and overall survival in this series were not attained.
    Strumal carcinoid of the ovary generally presents a benign behavior and surgery is curative in most cases. However, a small group of patients with this disease can undergo disease recurrence due to both the thyroid and the neuroendocrine (carcinoid) components. A follow-up in radically operated patients is therefore needed, particularly in those with a voluminous disease at diagnosis.
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  • 文章类型: Case Reports
    几种肿瘤产生于纵隔内的不同结构。尽管每种类型的纵隔肿瘤都有特定的区室,可以发生从一个隔室到另一个隔室的生长进程。前纵隔是几种肿瘤的部位,对胸外科医师提出了有趣的诊断和治疗挑战。前纵隔是纵隔内大多数肿瘤生长的所在地。胸腺瘤和淋巴瘤是前纵隔最常见的病理。间质起源的肿瘤(血管瘤,淋巴管瘤,脂肪瘤)及其恶性对应物可能发生在任何纵隔区。前纵隔区不太常见的肿瘤是异位甲状腺和甲状旁腺肿瘤,生殖细胞肿瘤,间充质起源肿瘤,血管瘤,和宫颈纵隔积液。大多数纵隔生长通常在临床上保持沉默,直到它们变大并引起压迫症状。这里,我们介绍了一系列五个前纵隔肿瘤,包括孤立性良性畸胎瘤,纤维良性肿瘤,恶性纤维肉瘤,错构瘤软骨瘤,还有恶性胸腺瘤.
    Several tumors arise from different structures within the mediastinum. Although each type of mediastinal tumor has a predilection for a specific compartment, the progression of growth from one compartment to another can occur. The anterior mediastinum is the site of several tumors that pose interesting diagnostic and therapeutic challenges to thoracic surgeons. The anterior mediastinum is the seat of the majority of neoplastic growths within the mediastinum. Thymomas and lymphomas are the most common pathologies of the anterior mediastinum. Tumors of mesenchymal origin (hemangioma, lymphangioma, lipomas) and their malignant counterparts may occur in any of the mediastinal compartments. Less common tumors of the anterior mediastinal compartment are ectopic thyroid and parathyroid tumors, germ cell tumors, mesenchymal origin tumors, hemangiomas, and cervicomediastinal hygromas. Most of the mediastinal growths usually remain clinically silent until they become large and cause compressive symptoms. Here, we present a case series of five anterior mediastinal tumors consisting of solitary benign teratoma, fibrous benign tumor, malignant fibrosarcoma, hamartomatous chondroma, and malignant thymoma.
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  • 文章类型: Case Reports
    Spinal cord teratomas are rare. There are few reports of teratomas affecting the cervical spine and their association with spondylotic radiculopathy has not been described. A 59-year-old woman with history of fecal incontinence attended with cervical radicular pain radiating to upper limbs. Physical examination showed distal muscle hypotrophy and abolishment of bicipital, tricipital, and brachioradialis reflexes of the right arm, preserving proximal strength. Also, hiporreflexia and loss of proprioception in the right lower limb was observed. Magnetic resonance imaging showed an intramedullary mass at C7-T1, accompanied by intervertebral disk protrusions and dural sac compressions at the same level. One-stage posterior-anterior operative approach for tumor resection, decompression of the radiculopathy and replacement of intervertebral discs was performed. The histopathological diagnosis was for a mature teratoma. We described the first case of an intramedullary cervical teratoma associated with radiculopathy in an adult, providing evidence of rare long-lasting teratomas affecting the cervical spine.
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  • 文章类型: Case Reports
    Teratomas is a germ cell tumors, which is rare in the upper palatal and lingual. This article presents a patient with teratomas on the palate and tongue accompanied with cleft palate. The clinical manifestations and histopathological characteristics of teratomas are discussed according to relevant literatures.
    畸胎瘤是一种生殖细胞来源的肿瘤,发生于上腭及舌的畸胎瘤罕见。本文报道1例上腭及舌畸胎瘤伴不完全性腭裂的病例,并结合相关文献对其临床表现、组织病理学特点等进行讨论。.
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  • 文章类型: Journal Article
    Primary carcinoma of the fallopian tube represents <1% of all gynecological tumors, and benign tumors of the fallopian tube are encountered even less frequently. Mature teratomas of the fallopian tube and ovary are extremely rare, and to date, only a few cases have been reported. A 31-year-old woman presented with a left adnexal mass that was identified by pelvic ultrasonography during a regular checkup. The patient underwent laparoscopic left salpingectomy and left ovarian cystectomy. Histopathological examination of the removed tissue revealed features compatible with mature cystic teratomas of both the left fallopian tube and ovary. At 26 months post-surgery, the patient underwent a cesarean section at 39+2 weeks of gestation. A right ovarian cystic mass was incidentally identified during the procedure. Right ovarian cystectomy was performed, and histopathological analysis revealed the mass to be a teratoma. The patient continued to receive annual follow-up after surgical intervention and demonstrated no evidence of disease at a routine 2-year follow-up examination. The discussion of the present case is followed by a brief review of the literature.
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  • 文章类型: Journal Article
    Gastric teratoma is a rare tumor, accounting for less than 1 % of all teratomas in infants & children. To date, only about 102 cases have been reported in the literature. A 10 month old infant was brought with a history of upper abdominal mass which was otherwise asymptomatic. On evaluation it was diagnosed as gastric teratoma. On laparotomy the mass was found to be originating from lesser curvature of stomach. Mass was excised and histopathologically it was a mature cystic teratoma. No recurrence after 18 months of follow-up.
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  • 文章类型: Case Reports
    头部和颈部的畸胎瘤由于其模糊的起源,奇异的微观外观,不可预测的行为和通常戏剧性的临床表现是临床惊喜。本文重点介绍小儿头颈部畸胎瘤及其多样性和稀有性,并回顾了这组肿瘤的最新术语。
    Teratomas of the head and neck due to their obscure origin, bizarre microscopic appearance, unpredictable behaviour and often dramatic clinical presentation are a clinical surprise. This article focuses on pediatric head and neck teratomas and on their diversity and rarity and also reviews the recent terminology of this group of tumours.
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