TORS

TORS
  • 文章类型: Journal Article
    目的:经口机器人手术在口咽病理学的治疗模式中已经确立。Versius手术系统(CMRSurgical)是一种用于多种专业临床的机器人平台,但目前尚未在头部和颈部进行测试。这项研究利用手术创新的理想框架来前瞻性地评估和报告Versius的人类临床经验和单中心病例系列经口机器人手术(TORS)。
    方法:在理想框架阶段1和2a之后,该研究评估了Versius在从良性病例过渡到恶性病例之前在人类TORS中的表现。对系统设置进行了迭代调整,仪器仪表,和技术,按照理想的建议记录。评估标准包括成功完成程序,设置时间,手术时间,并发症,主观印象。对进行四臂手术的系统进行了进一步评估。
    结果:成功完成了30个TORS程序(15个良性,15恶性),无术中并发症或转换为开放手术。设置时间在研究期间显著减少。确定了仪器挑战,敦促需要针对TORS的特定工具。这项研究引入了四臂手术,展示Versius的独特能力,尽管观察到远端通路的局限性。
    结论:使用Versius手术系统是可行的。TORS专用仪器的开发将有利于性能和系统的更广泛采用。4臂手术是可能的,但需要进一步评估。建议进行多中心评估(IDEAL阶段2b)。
    OBJECTIVE: Transoral robotic surgery is well established in the treatment paradigm of oropharyngeal pathology. The Versius Surgical System (CMR Surgical) is a robotic platform in clinical use in multiple specialities but is currently untested in the head and neck. This study utilises the IDEAL framework of surgical innovation to prospectively evaluate and report a first in human clinical experience and single centre case series of transoral robotic surgery (TORS) with Versius.
    METHODS: Following IDEAL framework stages 1 and 2a, the study evaluated Versius to perform first in human TORS before transitioning from benign to malignant cases. Iterative adjustments were made to system setup, instrumentation, and technique, recorded in accordance with IDEAL recommendations. Evaluation criteria included successful procedure completion, setup time, operative time, complications, and subjective impressions. Further evaluation of the system to perform four-arm surgery was conducted.
    RESULTS: 30 TORS procedures were successfully completed (15 benign, 15 malignant) without intraoperative complication or conversion to open surgery. Setup time significantly decreased over the study period. Instrumentation challenges were identified, urging the need for TORS-specific instruments. The study introduced four-arm surgery, showcasing Versius\' unique capabilities, although limitations in distal access were observed.
    CONCLUSIONS: TORS is feasible with the Versius Surgical System. The development of TORS-specific instruments would benefit performance and wider adoption of the system. 4-arm surgery is possible however further evaluation is required. Multicentre evaluation (IDEAL stage 2b) is recommended.
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  • 文章类型: Case Reports
    The da Vinci single-port (SP) is utilized in transoral robotic surgery (TORS) procedures for malignant oropharyngeal tumors. We report a case utilizing the da Vinci SP in TORS for sialolith removal.
    A 75-year-old male with chronic right submandibular gland (SMG) sialadenitis underwent combined da Vinci SP TORS approach with sialendoscopy for multiple SMG sialoliths. We were unable to find a previous report of using the da Vinci SP in TORS for SMG sialolith removal.
    The da Vinci SP has been utilized in a combined TORS approach with sialendoscopy for SMG sialolith removal. The da Vinci SP\'s additional arm provides improved retraction, enabling optimal visualization, dissection, and preservation of important structures such as the lingual nerve.
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  • 文章类型: Journal Article
    背景:这项研究的目的是确定与手术切缘阳性或淋巴结囊外延伸(ECE)发生率相关的术前患者特征,这需要在经口机器人手术(TORS)后进行辅助放化疗。
    方法:我们对34例接受TORS治疗的原发性口咽癌患者进行了一项单机构回顾性研究。所有影像学检查均由一名神经放射科医师进行。手术边缘和ECE状态由单个头颈部病理学家确定。使用单变量分析检查了术前患者特征与阳性手术切缘和淋巴结ECE的关联。使用逻辑回归确定这些结果的独立预测因子。
    结果:术前,大多数患者患有早期疾病(7cT1和21cT2;10cN0).4例(12%)患者出现切缘阳性。23例(68%)患者出现临床阳性淋巴结。29例(85%)患者进行了颈淋巴结清扫术,其中19例淋巴结病理阳性,15例淋巴结ECE。Logistic回归显示术前淋巴结较大是ECE的独立预测因子(比值比,13.32[95%CI,1.46-121.43])。在21例临床淋巴结阳性的患者中,行颈部清扫术,ECE在术前淋巴结大小≥3.0的患者中更常见。<3.0厘米(92%vs.44%,P=0.046)。没有与阳性切缘相关的患者特征。
    结论:术前淋巴结较大的患者更容易出现ECE,因此在TORS后进行放化疗,具有潜在的更高的毒性率。在决定治疗方法时,应考虑淋巴结大小。需要进一步的研究来验证这些结果。
    BACKGROUND: The purpose of this study was to identify preoperative patient characteristics associated with the incidence of positive surgical margins or lymph node extracapsular extension (ECE), which necessitate adjuvant chemoradiation after transoral robotic surgery (TORS).
    METHODS: We conducted a single institution retrospective study of 34 consecutive patients with primary oropharyngeal cancer who underwent TORS. All imaging was reviewed by a single neuroradiologist. Surgical margins and ECE status were determined by a single head and neck pathologist. Associations of preoperative patient characteristics with positive surgical margins and lymph node ECE were examined using univariate analysis. Independent predictors of these outcomes were determined using logistic regression.
    RESULTS: Preoperatively, the majority of patients had early-stage disease (7 cT1 and 21 cT2; 10 cN0). Positive margins occurred in 4 (12 %) patients. A clinically positive lymph node was seen in 23 (68 %) patients. Neck dissection was performed in 29 (85 %) patients, among whom 19 had a pathologically positive lymph node and 15 had nodal ECE. Logistic regression showed that larger preoperative lymph node size was an independent predictor of ECE (odds ratio, 13.32 [95 % CI, 1.46-121.43]). Among the 21 patients with a clinically positive lymph node who underwent neck dissection, ECE was present more often in patients with a preoperative node size ≥ 3.0 vs. < 3.0 cm (92 % vs. 44 %, P = 0.046). There was no patient characteristic associated with positive margins.
    CONCLUSIONS: Patients with a larger preoperative lymph node appear more likely to have ECE, and thus be treated with chemoradiation after TORS, with a potentially higher rate of toxicity. Lymph node size should be taken into account when deciding upon treatment approaches. Further research is needed to validate these results.
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  • 文章类型: Case Reports
    在人乳头状瘤相关的口咽鳞状细胞癌中,手术治疗越来越受欢迎。机器人手术在口咽唾液起源肿瘤中起着不同的作用,手术是主要的基本方式。这种方式可以用于更好地进入口咽,避免唇裂入路下颌骨切开术。器官保存方法如口咽部鳞状细胞癌,像放化疗这样的非手术方式,在这类癌症中不受欢迎,在目前的情况下。在这种情况下,机器人辅助手术有助于通过避免下颌骨切开术来降低发病率。
    Surgical management is increasingly preferred in human papilloma-related oropharyngeal squamous cell carcinoma. Robotic surgery has a different role to play in oropharyngeal salivary origin tumors, where surgery is the primary essential modality. This modality may be used for better access to the oropharynx, avoiding a lip split approach with mandibulotomy. The organ preservation approach such as in oropharyngeal squamous cell carcinoma, with nonsurgical modalities like chemoradiotherapy, is not preferred in such cancers, as in the present case. In this context, robot-assisted surgery helps in reducing the morbidity by avoiding the mandibulotomy.
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  • 文章类型: Journal Article
    BACKGROUND: Cervical spondylodiscitis is a rare but severe complication of pharyngeal surgery.
    METHODS: This multicenter retrospective study reported all patients in the database of the French head and neck tumor study group (GETTEC) affected by cervical spondylodiscitis after transoral robotic surgery (TORS) for malignant pharyngeal tumor from January 2010 to January 2017.
    OBJECTIVE: To describe cases of post-TORS cervical spondylodiscitis, identify alarm signs, and determine optimal management of these potentially lethal complications.
    RESULTS: Seven patients from 6 centers were included. Carcinomas were located in the posterior pharyngeal wall. Tumor stage was T1 or T2. All patients had risk factors for spondylodiscitis. Mean time to diagnosis was 12.6days. The interval between surgery and spondylodiscitis diagnosis ranged from 20days to 4.5months, for a mean 2.1months. The most common symptom was neck pain (87%). Infections were polymicrobial; micro-organisms were isolated in 5 cases and managed by intravenous antibiotics, associated to medullary decompression surgery in 3 cases. Follow-up found favorable progression in 4 cases, and 3 deaths (mortality, 43%).
    CONCLUSIONS: This French multicenter study found elevated mortality in post-TORS spondylodiscitis, even in case of limited resection. Surgeons must be aware of this complication and alerted by persistent neck pain, fever, asthenia, impaired or delayed posterior pharyngeal wall wound healing or elevation of inflammatory markers. MRI is the most effective diagnostic radiological examination.
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  • 文章类型: Comparative Study
    OBJECTIVE: To examine pain after Transoral Robotic Surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC) versus traditional bilateral tonsillectomy in adults.
    METHODS: Pain evolvement was assessed in a prospective case-control design of 16 consecutive patients treated with TORS for early stage OPSCC versus 12 patients, who underwent bilateral tonsillectomy on suspicion of malignant disease. The TORS group received an optimized analgesia regime of preoperative oral celecoxib and gabapentin, intra- and postoperative high-dose intravenous dexamethasone, and regular postoperative oral contalgin, gabapentin, celecoxib, paracetamol and rescue morphine. The tonsillectomy group received the departmental standard analgesia regime with low-dose preoperative oral dexamethasone, celecoxib and paracetamol. Postoperative regular analgesia consisted of oral NSAID and paracetamol with weak opioids prescribed as required. Pain intensity was recorded at rest and during swallowing twice a day.
    RESULTS: The median pain intensity on postoperative day (POD) 1-4 was 2 in the TORS group versus 4.5 in the tonsillectomy group. From POD 5-10 median pain intensity was 3.5 and 4, respectively. The median length of stay was 5 days in the TORS group and less than 24 hours in the tonsillectomy group.
    CONCLUSIONS: With an optimized analgesia regime TORS for OPSCC can be performed with postoperative pain levels comparable to bilateral tonsillectomy in adults.
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