菌群失调是由外部和内部宿主因素导致的肠道微生物群改变的临床状况。它与胃肠道和肠外改变密切相关,所以它的症状是广泛的和非特异性的。迄今为止,仍然存在差距,限制专业人员及时诊断和开出适当的治疗处方。我们的目标是综合现有的文献,这些文献涉及早期发现肠道菌群失调患者的临床参数和使用益生菌作为辅助治疗最常见的临床事件。在PubMed中对文献进行了范围审查,Embase,科克伦,和BVS(西班牙语中的BibliotecaVirtualenSalud)数据库,用于过去5年中发表的文章。与临床表现相关的主要研究和文献综述,菌群失调筛查,并纳入益生菌作为成人和儿科患者的辅助治疗。检索到23篇文章,其中最常报告的症状是腹胀,腹痛,和腹泻。慢性和代谢性疾病,其中病症与菌群失调最密切相关。根据症状学和病因学,菌群失调通常用益生菌治疗。菌群失调,经常与腹泻有关,应该考虑其他症状,如腹胀和疼痛,以及易感条件和患者风险因素。益生菌通常用作抗生素相关性腹泻的辅助治疗,肠易激综合征,和儿童过敏性疾病。最常用的益生菌是威兹曼尼亚凝结菌(以前称为凝结芽孢杆菌),克劳氏碱性芽孢杆菌(原名克劳氏芽孢杆菌),鼠李糖乳杆菌,罗伊利氏杆菌,和布拉氏酵母菌.
Dysbiosis is a clinical condition marked by altered gut microbiota resulting from external and internal host factors. It is strongly associated with gastrointestinal and extraintestinal alterations, so its symptomatology is broad and nonspecific. To date, gaps remain that limit professionals from making a timely diagnosis and prescribing the appropriate treatment. We aim to synthesize existing literature regarding clinical parameters for the early detection of patients with intestinal dysbiosis and the clinical events in which the use of probiotics as adjuvant therapy is most frequently reported. A scoping
review of the literature was conducted in PubMed, Embase, Cochrane, and BVS (Biblioteca Virtual en Salud in Spanish) databases for articles published in the last 5 years. Primary studies and literature reviews related to clinical presentation, dysbiosis screening, and probiotics as adjuvant therapy for adult and pediatric patients were included. Twenty-three articles were retrieved in which the most frequently reported
symptoms were abdominal distension, abdominal pain, and diarrhea. Chronic and metabolic diseases where the conditions most strongly associated with dysbiosis. Depending on symptomatology and etiology, dysbiosis is often treated with probiotics. Dysbiosis, often linked to diarrhea, should be considered with other
symptoms like abdominal distension and pain, along with predisposing conditions and patient risk factors. Probiotics are commonly used as co-adjuvant treatments for antibiotic-associated diarrhea, irritable bowel syndrome, and childhood allergic diseases. The most commonly used probiotics were Weizmannia coagulans (formerly B. coagulans), Alkalihalobacillus clausii (formerly Bacillus clausii), Lacticaseibacillus rhamnosus, Limosilactobacillus reuteri, and Saccharomyces boulardii.