黄酮类化合物-一类低分子量的次级代谢产物-在整个植物界中普遍存在且聚宝盆。在结构上,主要结构由具有不同取代模式的C6-C3-C6环组成,从而获得许多子类,例如:黄酮醇,黄酮木脂素,类黄酮苷,flavans,花青素,极光,花青素,黄酮,新类黄酮,查尔酮,异黄酮,黄酮和黄烷酮。黄酮类化合物被评估为具有类似药物的性质,因为它们具有不同的治疗活性,可以起到心脏保护作用,抗病毒,抗糖尿病药,抗炎,抗菌,抗癌,还可以对抗阿尔茨海默病和其他疾病。然而,关于它们的结构和生物活性之间关系的信息很少。因此,本综述试图总结黄酮类化合物的所有治疗活性,它们的作用机制和结构活动关系。
Flavonoids -a class of low molecular weight secondary metabolites- are ubiquitous and cornucopia throughout the plant kingdom. Structurally, the main structure consists of C6-C3-C6 rings with different substitution patterns so that many sub-classes are obtained, for example: flavonols, flavonolignans, flavonoid glycosides, flavans, anthocyanidins, aurones, anthocyanidins, flavones, neoflavonoids, chalcones, isoflavones, flavones and flavanones. Flavonoids are evaluated to have drug like nature since they possess different therapeutic activities, and can act as cardioprotective, antiviral, antidiabetic, anti-inflammatory, antibacterial, anticancer, and also work against Alzheimer\'s disease and others. However, information on the relationship between their structure and biological activity is scarce. Therefore, the present
review tries to summarize all the therapeutic activities of flavonoids, their mechanisms of action and the structure activity relationship.