背景:在医学研究中的随机对照试验(RCT)中,将应用的干预措施与常规治疗(TAU)作为对照条件进行比较。当前研究的目的是研究如何将TAU的概念描述为评估抑郁症治疗的RCT中的对照条件。焦虑综合征,和初级保健中与压力相关的精神障碍。
方法:对符合PRISMA标准的RCT中使用TAU作为对照组的RCT进行系统评价。我们使用了一个多学科数据库(Scopus),一个数据库专注于护理(Cinahl),和一个医疗数据库(PubMed)。搜索于2021年11月和2022年5月进行。
结果:纳入的32项研究包括7803名参与者。TAU的内容分类如下:1)TAU的基本描述缺乏详细说明以及对当地或国家指南的参考,2)TAU的适度描述,包括对国家或地方指南的参考或详细描述3)TAU的高级描述,包括对国家指南的参考和包含五个关键概念的详细描述:早期评估,可访问性,心理治疗,药物,体格检查.18项研究有基础,11中度,以及TAU的3种高级描述。
结论:限制是仅包括以英文发表的研究。
结论:本研究为TAU提供了一种具有三种分类水平的评估工具。在初级保健中进行的RCT研究中,对TAU的描述仍然不足,这可能会影响结果的解释。在未来的研究中,建议对TAU进行详细描述。
In randomized controlled trials (RCTs) within medical research, applied interventions are compared to treatment-as-usual (TAU) as the control condition. The aim of the current study was to examine how the concept of TAU is described when used as control condition in RCTs evaluating treatments for depression, anxiety syndromes, and stress-related mental disorders in primary care.
A systematic
review of RCTs utilizing TAU as control group in the RCT in accordance with PRISMA standards was conducted. We used one multidisciplinary database (Scopus), one database focused on nursing (Cinahl), and one medical database (PubMed). The searches were conducted in November 2021 and May 2022.
The included 32 studies comprised of 7803 participants. The content of TAU was classified as follows: 1) Basic descriptions of TAU lacking a detailed account as well as reference to local or national guidelines, 2) Moderate description of TAU including reference to national or local guidelines or a detailed description 3) Advanced description of TAU including references to national guidelines and a detailed description containing five key concepts: early assessment, accessibility, psychological treatment, medication, somatic examination. 18 studies had basic, 11 moderate, and 3 advanced descriptions of TAU.
The limitations were that only studies published in English were included.
The current study provides an assessment tool with three classification levels for TAU. The description of TAU is still insufficient in RCT studies conducted in primary care, which may affect the interpretation of results. In future research a detailed description of TAU is recommended.