Strategy

Strategy
  • 文章类型: Journal Article
    该研究旨在确定一些干预措施,以改善COVID-19大流行期间护士的心理健康。
    本研究中使用的数据是EBSCOhost,ProQuest,泰勒和弗朗西斯,科学直接,还有JSTOR.搜索这些研究以获取可用的全文文章。我们使用了偏见风险评估工具,即,乔安娜·布莱特研究所横断面研究工具的质量评估清单,队列研究,和随机对照试验。
    本综述共纳入8项研究。应对COVID-19护士心理社会问题的干预措施包括2类:(1)预防心理社会问题的干预措施-基于模拟的团队合作培训,心理健康促进策略,和预审,分诊,预防,和控制2019年冠状病毒疾病(COVID-19)评估培训;(2)克服COVID-19护士经历的心理社会问题的干预措施-移动健康计划,干预森林,情感自由技巧,远程咨询和心理健康干预。
    尽管有限制,我们能够对纳入研究的偏倚风险进行完整评估,这些研究提供了可靠的研究信息.建议医院可以提供干预措施,以提高护士的心理幸福感。
    UNASSIGNED: The study aimed to identify some interventions to improve the psychological well-being of nurses during the COVID-19 pandemic.
    UNASSIGNED: The data used in this study are EBSCOhost, ProQuest, Taylor & Francis, Science Direct, and JSTOR. These studies were searched for available full-text articles. We used tools for risk of bias assessment, namely, the quality assessment checklist of Joanna Bright Institute tools for cross-sectional studies, cohort studies, and randomized controlled trials.
    UNASSIGNED: A total of eight studies were included in this review. The interventions in dealing with the psychosocial problems of COVID-19 nurses consisted of 2 categories: (1) interventions to prevent psychosocial problems - simulation-based teamwork training, mental health promotion strategies, and pre-examination, triage, prevention, and control of Coronavirus disease 2019 (COVID-19) evaluation training; and (2) interventions to overcome psychosocial problems experienced by COVID-19 nurses - mobile wellness programs, intervention FOREST, emotional freedom techniques, tele-counselling and mental health interventions.
    UNASSIGNED: Despite limitations, we were able to perform a complete assessment of the risk of bias in included studies that provide reliable information on the studies. It is recommended that hospitals can provide interventions to improve the psychological well-being of nurses.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    癫痫占神经系统疾病全球负担的很大一部分。这篇综述旨在评估人口统计学,临床特征,根据2018年至2023年发表的研究,沙特阿拉伯癫痫患者的管理。使用PubMed进行了系统评价,Medline,Embase,和Cochrane图书馆从2018年1月到2023年1月,其中与流行病学相关的关键术语,临床特征,治疗,沙特阿拉伯的癫痫治疗策略被用于搜索相关研究。所有这一时期用英语发表的相关文章都包括在内,和关于作者的数据,研究的年份,样本量,研究设计,人口特征,临床特征,并收集治疗策略。男性优势,有6-24.9%的癫痫家族史,局灶性癫痫和强直阵挛性癫痫的分布相等,脑电图异常19.7-70%,单药治疗的患病率较高是本综述的主要发现.
    Epilepsy accounts for a large part of the global burden of neurological disorders. This review aimed to assess the demographics, clinical characteristics, and management of patients with epilepsy in Saudi Arabia based on studies published from 2018 to 2023. A systematic review was carried out using PubMed, Medline, Embase, and Cochrane Library from January 2018 to January 2023, where key terms related to the epidemiology, clinical characteristics, treatment, and management strategy of epilepsy in Saudi Arabia were used to search for related studies. All relevant articles published in this period in the English language were included, and data about authors, year of the study, sample size, study design, demographic characteristics, clinical characteristics, and treatment strategy were collected. A male preponderance, a 6-24.9% family history of epilepsy, an equal distribution of focal and tonic-clonic epilepsy, EEG abnormalities of 19.7-70%, and a higher prevalence of monotherapy regimens were the main findings of this review.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:医疗机构的领导者正在努力应对不断上涨的费用和对医疗服务的需求激增。作为回应,他们越来越多地采用人工智能(AI)技术来改善患者护理流程,减轻业务负担,并有效提高医疗质量。
    目标:在本文中,我们将回顾现有文献,并综合有关领导力在推动医疗保健领域AI转型中的作用的见解。
    方法:我们对多个数据库进行了全面的搜索,包括MEDLINE(通过Ovid),PsycINFO(通过Ovid),CINAHL(通过EBSCO),BusinessSourcePremier(通过EBSCO),和加拿大商业与时事(通过ProQuest),2015年至2023年6月发表的关于医疗保健行业人工智能转型的文章。具体来说,我们专注于实证研究,特别强调领导力。我们用了一个归纳法,定性绘制证据的专题分析方法。根据PRISMA-ScR(系统评论的首选报告项目和范围评论的荟萃分析扩展)报告了研究结果。
    结果:对2,813篇独特摘要的回顾导致检索了97篇全文文章以供评估,其中我们包括22篇文章供审查。我们对文献的映射表明,医疗保健行业内领先的AI转型涉及导航受复杂的各种监管影响的不断变化的格局。技术和组织环境。技术,战略,操作,需要组织领导才能推动AI转型。跨技术领域的领导力,适应性,和人际交往能力对于成功驾驭这一转变至关重要。
    结论:结论:这篇综述提供了对领导力职能领域的见解,必要的领导能力,以及塑造与人工智能转型相关的领导行为的环境因素。未来对医疗保健中人工智能的研究应该将领导力作为一个关键因素进行调查,并检查功能领域的相互关联性。领导能力和背景,通过严格的研究方法,以加强现有的证据基础。
    背景:
    BACKGROUND: The leaders of health care organizations are grappling with rising expenses and surging demands for health services. In response, they are increasingly embracing artificial intelligence (AI) technologies to improve patient care delivery, alleviate operational burdens, and efficiently improve health care safety and quality.
    OBJECTIVE: In this paper, we map the current literature and synthesize insights on the role of leadership in driving AI transformation within health care organizations.
    METHODS: We conducted a comprehensive search across several databases, including MEDLINE (via Ovid), PsycINFO (via Ovid), CINAHL (via EBSCO), Business Source Premier (via EBSCO), and Canadian Business & Current Affairs (via ProQuest), spanning articles published from 2015 to June 2023 discussing AI transformation within the health care sector. Specifically, we focused on empirical studies with a particular emphasis on leadership. We used an inductive, thematic analysis approach to qualitatively map the evidence. The findings were reported in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews) guidelines.
    RESULTS: A comprehensive review of 2813 unique abstracts led to the retrieval of 97 full-text articles, with 22 included for detailed assessment. Our literature mapping reveals that successful AI integration within healthcare organizations requires leadership engagement across technological, strategic, operational, and organizational domains. Leaders must demonstrate a blend of technical expertise, adaptive strategies, and strong interpersonal skills to navigate the dynamic healthcare landscape shaped by complex regulatory, technological, and organizational factors.
    CONCLUSIONS: In conclusion, leading AI transformation in healthcare requires a multidimensional approach, with leadership across technological, strategic, operational, and organizational domains. Organizations should implement a comprehensive leadership development strategy, including targeted training and cross-functional collaboration, to equip leaders with the skills needed for AI integration. Additionally, when upskilling or recruiting AI talent, priority should be given to individuals with a strong mix of technical expertise, adaptive capacity, and interpersonal acumen, enabling them to navigate the unique complexities of the healthcare environment.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:受过国际教育的护士(IEN)从发展中国家向发达国家的迁移日益增加,这凸显了实施促进其工作场所过渡的融合战略的重要性,提高工作满意度和专业能力。
    目的:混合方法系统综述旨在综合当前有关IEN在整个过渡过程中影响工作满意度和专业能力的因素的文献,包括预迁移,迁移,和迁移后时期。
    方法:本研究从2013年到2023年进行了混合方法系统综述,使用CINAHL,Scopus,和PubMed数据库并雇用人口,干预措施,比较,结果(PICO)框架。质量评估采用混合方法评估工具(MMAT),数据分析遵循收敛并行设计。数据综合是叙述式的,文献综述遵循系统评价和荟萃分析(PRISMA)指南的首选报告项目。
    结果:在565篇文章中,11项研究(8项定性,两个定量,和一种混合方法)符合纳入标准。确定了影响IEN工作满意度和专业能力的三个关键主题:迁移前和部署前的需求,工作场所整合方面的挑战,以及移民后的职业挑战和保留策略。
    结论:该研究主要针对从发展中国家招募的IENs,可能会限制调查结果对其他地区或国家的IEN的普遍性。此外,在现有的研究中,来自发达国家的护士也是移民的,这进一步限制了研究成果的适用性。
    结论:必须重新考虑迁移前的语言要求,并评估在整合期间完成这些要求的可行性,以提高IEN的工作满意度和专业能力。此外,提高IEN工作满意度的关键因素包括提供个性化支持,解决管理障碍,促进职业发展,高效地管理工作负载,并促进医疗团队内部的有效沟通。
    BACKGROUND: The increasing migration of internationally educated nurses (IENs) from developing to developed countries highlights the importance of implementing integration strategies that facilitate their workplace transition, leading to improved job satisfaction and professional competence.
    OBJECTIVE: The mixed-methods systematic review aimed to synthesise the current literature on factors influencing job satisfaction and professional competencies among IENs throughout their transition process, including the pre-migration, migration, and post-migration periods.
    METHODS: This study conducted a mixed-methods systematic review from 2013 to 2023, using the CINAHL, Scopus, and PubMed databases and employing a Population, Interventions, Comparisons, Outcomes (PICO) framework. Quality assessment employed the Mixed Methods Appraisal Tool (MMAT), and data analysis followed a convergent parallel design. Data synthesis was presented narratively, and the literature review adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
    RESULTS: Out of 565 articles, eleven studies (eight qualitative, two quantitative, and one mixed-method) met the inclusion criteria. Three key themes that influenced job satisfaction and professional competencies among IENs were identified: pre-migration and pre-deployment demands, challenges in workplace integration, and post-migration career challenges and retention strategies.
    CONCLUSIONS: The study primarily focused on IENs recruited from developing countries, potentially limiting the generalisability of the findings to IENs from other regions or countries. Furthermore, the inclusion of nurses from developed countries who also migrated was limited in the available studies, which further restricts the applicability of the research findings.
    CONCLUSIONS: It is essential to reconsider the pre-migration language requirements and evaluate the feasibility of completing them during the integration period to enhance the job satisfaction and professional competencies of IENs. Additionally, key factors for improving job satisfaction among IENs include providing personalised support, addressing managerial barriers, facilitating career advancement, efficiently managing workloads, and promoting effective communication within the healthcare team.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    全球应急部门(ED)面临不断升级的挑战,如人满为患、资源限制,患者需求增加。本研究旨在识别和分析策略,以提高ED的结构性能,专注于减少过度拥挤,优化资源配置,改善患者预后。通过对文献和观察研究的全面回顾,这项研究强调了各种方法的有效性,包括分类优化,动态人员配备,技术集成,和战略资源管理。关键发现表明,量身定制的策略,例如实施高级分诊协议和利用远程医疗,可以显著减少等待时间和提高患者吞吐量。此外,有证据表明,动态人员配置模型和尖端诊断工具的整合有助于提高运营效率和护理质量.这些策略,当合并时,为ED面临的复杂挑战提供多方面的解决方案,有希望更好的患者护理和满意度。该研究强调需要采取全面的方法,结合组织和技术创新,以满足不断变化的紧急医疗需求。
    Emergency Departments (EDs) globally face escalating challenges such as overcrowding, resource limitations, and increased patient demand. This study aims to identify and analyze strategies to enhance the structural performance of EDs, with a focus on reducing overcrowding, optimizing resource allocation, and improving patient outcomes. Through a comprehensive review of the literature and observational studies, the research highlights the effectiveness of various approaches, including triage optimization, dynamic staffing, technological integration, and strategic resource management. Key findings indicate that tailored strategies, such as implementing advanced triage protocols and leveraging telemedicine, can significantly reduce wait times and enhance patient throughput. Furthermore, evidence suggests that dynamic staffing models and the integration of cutting-edge diagnostic tools contribute to operational efficiency and improved quality of care. These strategies, when combined, offer a multifaceted solution to the complex challenges faced by EDs, promising better patient care and satisfaction. The study underscores the need for a comprehensive approach, incorporating both organizational and technological innovations, to address the evolving needs of emergency healthcare.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    在印度青少年健康战略(IAHS)的背景下,需要对青少年的健康需求进行细致入微的了解,以便为改善印度青少年健康和福祉的政策干预提供信息。
    使用来自全球疾病负担的数据,受伤,和2019年风险因素研究,我们确定了导致寿命损失(YLL)的十大原因,残疾生活年(YLDs),和残疾调整寿命年(DALYs),按性别和年龄组(10-14岁和15-19岁)分列,2019年印度及其各州。向IAHS通报改善印度青少年健康所需的改进或扩展重点,我们回顾了在IAHS中解决疾病负担的十大原因的程度,以及在青少年友好健康诊所监测信息系统(AFHCMIS)和健康管理信息系统(HMIS)中捕获的青少年服务利用数据中的年龄和性别分类。我们还审查了IAHS操作框架中确定的数据来源中IAHS结果指标在人口一级的数据捕获中的可用性以及年龄和性别分类。
    10-14岁和15-19岁年龄组的女性有675万和925万DALY,分别,其中39.1%和44.2%为YLL;男性的相应DALYs分别为671万和965万(42.3%和41.1%YLL),分别。在IAHS的6个主题领域中,确定的大多数战略和指标都是针对性健康和生殖健康,其次是营养,在青少年中,这些疾病广泛地占YLD而不是YLL。与致命疾病和病症的疾病负担相比,IAHS存在显着差距,传染病,和非传染性疾病。在15-19岁的男性和女性中,损伤占YLL的65.9%和45.3%,10-14岁男性占40.8%。具体来说,道路伤害(15.3%,95%UI11.0-18.0)和自我伤害(11.3%,95%UI8.7-14.2)占15-19年伤害死亡的大部分,而溺水(7.7%95%UI5.8-9.6)和道路伤害(6.9%,95%UI4.7-8.6)是10-14岁男性中受伤死亡最多的人。然而,只有自我伤害和基于性别的暴力在IAHS中被特别处理,对其他伤害采取非特异性干预措施.腹泻,下呼吸道感染,疟疾,脑炎,结核病,伤寒,肝硬化,和肝炎是导致青少年YLL和DALYs的其他疾病,但IAHS和AFHCMIS下的服务提供中均未解决这些问题。在HMIS中捕获的死亡原因数据中没有年龄或性别分类,以了解青少年的死亡率。对于人口水平的IAHS结果指标,在人口调查中,不分性别的10-14年的数据采集在很大程度上缺失,没有一项调查采集15-19岁女性或男性的身体活动不足和心理健康指标数据.
    与印度青少年致命和非致命疾病负担的主要原因相比,IAHS主题重点存在相当大的差异,以及在监测IAHS结果指标的人口水平数据的可用性方面,可能会对改善印度的青少年健康构成重大限制。决策者可以利用本文中的发现来完善旨在改善青少年健康和福祉的行动。
    比尔和梅琳达·盖茨基金会。
    UNASSIGNED: A nuanced understanding of the health needs of adolescents in the context of the India Adolescent Health Strategy (IAHS) is needed to inform policy interventions for improving the health and well-being of adolescents in India.
    UNASSIGNED: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, we identified the top ten causes of years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) disaggregated by sex and age group (10-14 and 15-19 years) for India and its states in 2019. To inform the IAHS of refinement or expansion in focus needed to improve adolescent health in India, we reviewed the extent to which the top 10 causes of disease burden are addressed in the IAHS, and the availability of and age- and sex-disaggregation in the service utilisation data for adolescents captured in the Adolescent Friendly Health Clinic monitoring information system (AFHC MIS) and Health Management Information System (HMIS). We also reviewed the availability of and age-and sex-disaggregation in the data capture at the population level for the IAHS outcome indicators in the data sources identified in the IAHS operational framework.
    UNASSIGNED: Females in the 10-14 and 15-19 years age groups suffered 6.75 million and 9.25 million DALYs, respectively, 39.1% and 44.2% of which were YLLs; the corresponding DALYs for males were 6.71 million and 9.65 million (42.3% and 41.1% YLLs), respectively. Within the 6 thematic areas of the IAHS, most strategies and indicators identified are for sexual and reproductive health followed by nutrition, and broadly these conditions accounted for YLDs and not YLLs in adolescents. Significant gaps in the IAHS in comparison to the disease burden for fatal diseases and conditions were seen across injuries, communicable diseases, and non-communicable diseases. Injuries accounted for 65.9% and 45.3% of YLLs in males and females aged 15-19 years, and 40.8% in males aged 10-14 years. Specifically, road injuries (15.3%, 95% UI 11.0-18.0) and self-harm (11.3%, 95% UI 8.7-14.2) accounted for most of the injury deaths in 15-19 years whereas drowning (7.7% 95% UI 5.8-9.6) and road injuries (6.9%, 95% UI 4.7-8.6) accounted for the most injury deaths in 10-14 years males. However, only self-harm and gender-based violence are specifically addressed in the IAHS with non-specific interventions for other injuries. Diarrhoea, lower respiratory infections, malaria, encephalitis, tuberculosis, typhoid, cirrhosis, and hepatitis are the other disease conditions accounting for YLLs and DALYs in adolescents but these are neither addressed in the IAHS nor in service provision under the AFHC MIS. There is no age- or sex-disaggregation in the cause of death data captured in the HMIS to allow an understanding of mortality in adolescents. For the IAHS outcome indicators at the population level, data capture for the 10-14 years irrespective of sex was largely missing from the population surveys and none of the surveys captured data for either females or males aged 15-19 years for physical inactivity and mental health indicators.
    UNASSIGNED: The considerable differences seen in the IAHS thematic focus as compared with the leading causes of fatal and non-fatal disease burden in adolescents in India, and in the availability of population-level data to monitor the outcome indicators of the IAHS can pose substantial limitations for improving adolescent health in India. The findings in this paper can be utilized by decision makers to refine action aimed at improving adolescent health and well-being.
    UNASSIGNED: Bill & Melinda Gates Foundation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    澳大利亚国家生育战略以妇女为中心的护理:澳大利亚生育服务的战略方向(战略)于2019年11月由联邦政府发布。它的制定是为了就有效提供以妇女为中心的产妇护理提供国家指导。该战略围绕四个安全价值观构建,尊重,选择,和访问,并以十二项以妇女为中心的护理原则为基础。通过检查以前的研究,这项审查的目的是提供一个基本的理解,如何提供产妇保健服务是在这些核心价值方面得到满足。通过使用策略值的四个数据库对澳大利亚文献进行了系统的搜索,其中41篇文章符合选择标准。包括的文章主要在2019年前发表,在战略发表之前提供了对澳大利亚产妇护理提供的基线理解。研究结果表明,这四个价值观与女性的价值观一致;然而,女性并不总是按照价值观接受护理,特别是来自优先人群的妇女。女性优先考虑自己和孩子的安全,阐明了与产妇护理提供者建立尊重关系的必要性,想要自主做出自己的决定,并期望获得适当的,当地,产妇服务。此外,虽然确实存在适当的护理口袋,这些更可能发生在单一服务级别,而不是更广泛地发生在人口级别。这意味着该战略是必要的,必须通过协调一致的国家对策来优先考虑其运作,以更好地满足澳大利亚妇女的产妇护理需求。需要进一步的研究来确定战略的有效性。
    Australia\'s national maternity strategy Woman-centred care: strategic directions for Australian maternity services (the Strategy) was released by the federal government in November 2019. It was developed to provide national guidance on the effective provision of woman-centred maternity care. The Strategy is structured around four values of safety, respect, choice, and access, and underpinned by twelve principles of woman-centred care. By examining previous research, this review aims to provide a baseline understanding of how maternity care provision is being met in relation to these core values. A systematic search of Australian literature was undertaken via four databases using the Strategy\'s values and 41 articles met the selection criteria. Include articles were predominantly published pre-2019, providing a baseline understanding of Australian maternity care provision prior to the Strategy\'s publication. Findings suggest that the four values align with those of women; however, women were not always receiving care in accordance with the values, particularly among women from priority populations. Women prioritised safety for themselves and their babies, articulated the need for respectful relationships with maternity care providers, wanted autonomy to make their own decisions, and desired access to appropriate, local, maternity services. Additionally, while pockets of appropriate care do exist, these are more likely to occur at a single-service level than more broadly at a population level. This implies the Strategy is needed, and its operationalisation must be prioritised through a coordinated national response to better meet the maternity care needs of Australian women. Further research is warranted to determine the Strategy\'s effectiveness.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:没有足够的数据来告知危重患者针对GN感染的最佳抗菌治疗持续时间和类型。
    方法:基于通过PubMed和Cochrane进行文献检索的叙事综述,使用以下关键词:“多药耐药(MDR)”,“广泛耐药(XDR)”,“泛耐药(PDR)”,“难以治疗(DTR)革兰氏阴性感染,\"\"抗生素持续治疗\",\“抗生素联合治疗\”\“抗生素单药治疗\”\“革兰氏阴性菌血症\”,“革兰氏阴性肺炎”,和“革兰氏阴性腹腔感染”。
    结果:目前的文献数据表明,由于产ESBL的全球患病率较高(45-50%),采用更长(≥10-14天)疗程的协同联合治疗。MDR(35%),XDR(15-20%),PDR(5.9-6.2%),和碳青霉烯酶(CP)/金属-β-内酰胺酶(MBL)产生(12.5-20%)革兰氏阴性(GN)微生物(即,肺炎克雷伯菌,铜绿假单胞菌,和鲍曼不动杆菌)。另一方面,较短疗程(≤5~7天)的单药治疗应仅限于治疗由GN引起的感染,且抗生素敏感性较高(≥3种抗生素).一般方法应基于(i)在MDR-GN的情况下,第三代或下一代头孢菌素±喹诺酮/氨基糖苷类;(ii)碳青霉烯类±磷霉素/氨基糖苷类用于广谱β-内酰胺酶(ESBLs);(iii)旧药与新的广谱β-内酰胺酶抑制剂的关联PDR,和CP微生物。治疗药物监测(TDM)结合最低抑菌浓度(MIC),杀菌vs.抑菌抗生素,以及耐药性风险预测因子的存在(与患者相关,抗生素,和微生物)应代表影响治疗GN感染的抗菌策略的变量。
    结论:尽管结果中描述了治疗策略,临床医生必须记住,所有治疗决策都是动态的,需要根据患者的临床和微生物学反应进行频繁的重新评估。
    BACKGROUND: Not enough data exist to inform the optimal duration and type of antimicrobial therapy against GN infections in critically ill patients.
    METHODS: Narrative review based on a literature search through PubMed and Cochrane using the following keywords: \"multi-drug resistant (MDR)\", \"extensively drug resistant (XDR)\", \"pan-drug-resistant (PDR)\", \"difficult-to-treat (DTR) Gram-negative infection,\" \"antibiotic duration therapy\", \"antibiotic combination therapy\" \"antibiotic monotherapy\" \"Gram-negative bacteremia\", \"Gram-negative pneumonia\", and \"Gram-negative intra-abdominal infection\".
    RESULTS: Current literature data suggest adopting longer (≥10-14 days) courses of synergistic combination therapy due to the high global prevalence of ESBL-producing (45-50%), MDR (35%), XDR (15-20%), PDR (5.9-6.2%), and carbapenemases (CP)/metallo-β-lactamases (MBL)-producing (12.5-20%) Gram-negative (GN) microorganisms (i.e., Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumanii). On the other hand, shorter courses (≤5-7 days) of monotherapy should be limited to treating infections caused by GN with higher (≥3 antibiotic classes) antibiotic susceptibility. A general approach should be based on (i) third or further generation cephalosporins ± quinolones/aminoglycosides in the case of MDR-GN; (ii) carbapenems ± fosfomycin/aminoglycosides for extended-spectrum β-lactamases (ESBLs); and (iii) the association of old drugs with new expanded-spectrum β-lactamase inhibitors for XDR, PDR, and CP microorganisms. Therapeutic drug monitoring (TDM) in combination with minimum inhibitory concentration (MIC), bactericidal vs. bacteriostatic antibiotics, and the presence of resistance risk predictors (linked to patient, antibiotic, and microorganism) should represent variables affecting the antimicrobial strategies for treating GN infections.
    CONCLUSIONS: Despite the strategies of therapy described in the results, clinicians must remember that all treatment decisions are dynamic, requiring frequent reassessments depending on both the clinical and microbiological responses of the patient.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目前,食品安全危害已成为全球公共卫生的最重要威胁之一。考虑到全球食品安全领域的众多危机,区域,和国家层面,以及它们对消费者身心健康的影响,评估每个国家的风险沟通策略非常重要。食品安全风险沟通(FSRC)旨在为个人提供保护其健康免受食品安全风险的手段,并就食品风险做出明智的决策。本研究的目的是将FSRC作为风险分析的关键部分之一,考虑到食品污染的普遍性和最近与食品有关的危机,它的重要性。此外,提到了FSRC的实施阶段。在FSRC中,必须遵守原则和先决条件。如今,FSRC有各种策略。FSRC的不同平台正在迅速发展。根据目标群体选择和评估适当的策略,利益相关者的共识,风险评估员和风险管理人员的合作与协调对改善和实施FSRC具有重大影响。
    Currently, food safety hazards have introduced as one of the most important threats to public health worldwide. Considering numerous crises in the field of food safety at global, regional, and national levels, and their impact on the physical and mental health of consumers, it is very vital to evaluate risk communication strategies in each country. Food safety risk communication (FSRC) aims to provide the means for individuals to protect their health from food safety risks and make informed decisions about food risks. The purpose of this study is to present FSRC as one of the key parts of risk analysis, its importance considering the prevalence of food contamination and recent crises related to food. Additionally, the stages of implementation of FSRC are mentioned. In FSRC, it is essential to comply with the principles and prerequisites. There are various strategies for FSRC nowadays. Different platforms for FSRC are rapidly evolving. Choosing and evaluating the appropriate strategy according to the target group, consensus of stakeholders, cooperation and coordination of risk assessors and risk managers have a significant impact in order to improve and implement FSRC.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Systematic Review
    废水基础设施在社会运行中起着不可或缺的作用,人类生产活动,和卫生安全。然而,气候变化对废水基础设施构成了严重威胁。迄今为止,缺乏全面的摘要,并对气候变化对废水基础设施的影响进行严格的证据评估。我们对科学文献进行了系统的回顾,灰色文学,和新闻。总的来说,检索到61,649份文件,其中96项被认为是相关的,并接受了详细分析。我们为所有收入环境中的城市制定了城市级决策的类型学适应策略,以应对废水结构的气候变化。84%和60%的研究集中在高收入国家和下水道系统,分别。溢出,破损,腐蚀是下水道系统的主要挑战,而淹没和处理性能的波动是污水处理厂面临的主要问题。为了适应气候变化的影响,制定了类型学适应战略,以提供一个简单的指南,为不同收入水平的城市快速选择脆弱废水设施的适应措施。鼓励未来的研究更多地关注与模型相关的改进/预测,气候变化对下水道以外的其他废水设施的影响,以及低收入或中低收入的国家。这项审查提供了见解,以全面了解气候变化对废水设施的影响,并促进应对气候变化的决策。
    Wastewater infrastructures play an indispensable role in society\'s functioning, human production activities, and sanitation safety. However, climate change has posed a serious threat to wastewater infrastructures. To date, a comprehensive summary with rigorous evidence evaluation for the impact of climate change on wastewater infrastructure is lacking. We conducted a systematic review for scientific literature, grey literature, and news. In total, 61,649 documents were retrieved, and 96 of them were deemed relevant and subjected to detailed analysis. We developed a typological adaptation strategy for city-level decision-making for cities in all-income contexts to cope with climate change for wastewater structures. 84% and 60% of present studies focused on the higher-income countries and sewer systems, respectively. Overflow, breakage, and corrosion were the primary challenge for sewer systems, while inundation and fluctuation of treatment performance were the major issues for wastewater treatment plants. In order to adapt to the climate change impact, typological adaptation strategy was developed to provide a simple guideline to rapidly select the adaptation measures for vulnerable wastewater facilities for cities with various income levels. Future studies are encouraged to focus more on the model-related improvement/prediction, the impact of climate change on other wastewater facilities besides sewers, and countries with low or lower-middle incomes. This review provided insight to comprehensively understand the climate change impact on wastewater facilities and facilitate the policymaking in coping with climate change.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号