Source control

源代码控制
  • 文章类型: Case Reports
    我们提出了一个威胁生命的产后急性坏死性胰腺炎病例。患者是一名37岁的女性,没有既往病史,通过剖腹产分娩了一名健康的男婴。二十天后,她因急性恶心出现在急诊科,非血性呕吐,腹胀,上腹部疼痛放射到背部。不到24小时后,尽管进行了积极的复苏,她还是进展为感染性休克,在ICU需要加压药支持。最初的CT成像显示整个胰腺有多个斑片状低密度,与严重的坏死性胰腺炎一致。由于难以获得感染的来源控制,她的住院更加复杂,艰难梭菌,和营养缺乏导致严重的失踪症。在接受多次经皮引流后,她于第59天出院,IV抗生素,和内镜下胃囊吻合术伴4例胰腺坏死切除术。自放电以来,患者因胰腺炎并发症需要再次入院两次.
    We present a life-threatening case of postpartum acute necrotizing pancreatitis. The patient is a 37-year-old female with no past medical history who delivered a healthy baby boy via cesarean section. Twenty days later, she presented to the emergency department with acute onset of nausea, non-bloody vomiting, abdominal bloating, and epigastric pain radiating to the back. Less than 24 hours later, she progressed into septic shock despite aggressive resuscitation, requiring vasopressor support in the ICU. Initial CT imaging showed multiple patchy hypodensities throughout the pancreas consistent with severe necrotizing pancreatitis. Her hospitalization was further complicated by difficulty obtaining source control of her infection, Clostridium difficile, and nutritional deficiencies that resulted in gross anasarca. She was discharged from the hospital on day 59 after undergoing multiple percutaneous drain placements, IV antibiotics, and endoscopic gastrocystostomy with four pancreatic necrosectomies. Since discharge, the patient has required readmission twice for complications from her pancreatitis.
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  • 文章类型: Case Reports
    背景:肺炎链球菌很少引起生殖道感染,但特别是在易感的情况下,它可能是阴道菌群的短暂部分,因此可能发生盆腔感染。与肺炎球菌性盆腔腹膜炎相关的可能病症包括使用宫内节育器,最近的分娩和妇科手术。这些事件的潜在机制可能是通过输卵管从生殖道上升感染。
    方法:我们介绍了一个健康的年轻女性,戴着月经阴道内杯,由肺炎链球菌引起的盆腔腹膜炎和肺炎。放射学发现右卵巢囊性形成和所有腹膜腔腹水积液后,进行了紧急探查腹腔镜检查和右卵巢切除术。腹部败血症消退后,实质巩固并发坏死性肺炎,因此患者接受了右下肺叶切除术。
    结论:月经杯是一种自保留的阴道内月经液收集装置,被认为是卫生棉条和护垫的安全替代品,使用与罕见的不良反应有关。很少有传染病病例被描述,其中潜在的机制可能包括细菌在子宫环境中积累的血液中复制,随后进入生殖道。
    结论:在罕见的肺炎球菌性盆腔腹膜炎中,考虑到所有可能的感染源是至关重要的,就像评估阴道内装置的可能参与一样,如今越来越多地使用,但其中潜在的并发症仍然描述不佳。
    BACKGROUND: Streptococcus pneumoniae infrequently causes genital tract infections but - in particular predisposing circumstances - it can be a transient part of vaginal flora and thus pelvic infections can occur. Possible conditions associated with pneumococcal pelvic-peritonitis include the use of intrauterine contraceptive devices, recent birth and gynecologic surgery. The underlying mechanism of these occurrences is likely to be the ascending infection from the genital tract via the fallopian tubes.
    METHODS: We present a case of pelvic-peritonitis and pneumonia due to Streptococcus pneumoniae in a healthy young woman wearing a menstrual endovaginal cup. Following the radiological findings of a cystic formation in the right ovary and ascites effusions in all peritoneal recesses an emergency exploratory laparoscopy with right ovariectomy was performed. After resolution of abdominal sepsis, parenchymal consolidation complicated into necrotizing pneumonia, hence the patient underwent a right lower lobectomy.
    CONCLUSIONS: The menstrual cup is a self-retaining intravaginal menstrual fluid collection device, considered as a safe alternative to tampons and pads, which use is associated with rare adverse effects. Few cases of infectious disease have been described, where the underlying mechanism may consist of bacterial replication within the blood accumulated in the uterine environment, with subsequent ascension into the genital tract.
    CONCLUSIONS: In the rare occurrence of pneumococcal pelvic-peritonitis considering all possible infectious sources is paramount, as is assessing the possible involvement of intravaginal devices, increasingly used nowadays but of which potential complications are still poorly described.
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  • 文章类型: Case Reports
    血清肿被定义为对损伤和手术的反应的浆液性液体集合,特别是乳房切除术和重建和腹部手术。大多数血清瘤是自限性的,出现在急性术后时期;然而,文献中也报道了手术后几年的血清肿诊断。以感染的血清瘤为来源的持续菌血症是一种罕见的实体。我们介绍了第一例报告的持续性菌血症,继发于感染的血清肿并伴有肺和前列腺的败血症,而在多次超声心动图上没有任何心内膜炎的证据。该病例突出了精心体检和源头控制在菌血症管理中的重要性。
    A seroma is defined as a serous fluid collection that develops as a response to injury and surgeries, particularly mastectomy and reconstructive and abdominal surgeries. The majority of the seromas are self-limiting and arise in the acute postoperative period; however, diagnosis of seroma several years after surgery has also been reported in the literature. Persistent bacteremia with infected seroma as a source is a rare entity. We present the first case to be reported of persistent bacteremia secondary to infected seroma with septic emboli to lungs and prostate without any evidence of endocarditis on multiple echocardiograms. This case highlights the importance of meticulous physical examination and source control in the management of bacteremia.
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  • 文章类型: Case Reports
    快速生长的分枝杆菌越来越被认为是病原体,在免疫功能低下和免疫功能正常的人群中,在过去的十年中,它们的发病率显著增加。肺部感染是最常见的,然而,任何器官都可能受到影响。这些感染的治疗费用很高,延长,并且通常抗菌素耐药性对成功的结果构成了重大挑战。源控制与抗微生物药物一起是治疗的基石。我们报告了一系列3例肺外快速生长的分枝杆菌感染患者,其中仅通过源控制即可成功治疗。
    Rapid growing mycobacteria have been increasingly recognized as pathogens, both in immunocompromised and immunocompetent population, and their incidence has increased over the last decade significantly. Pulmonary infections are the most common, however, any organ can be affected. The treatment of these infections is costly, prolonged, and often antimicrobial resistance poses a significant challenge to a successful outcome. The source control together with antimicrobials is the cornerstone of treatment. We report a case series of 3 patients with extrapulmonary rapid growing mycobacterial infections in whom the successful treatment was achieved with source control alone.
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