BACKGROUND: The aim of the study was to identify the variables of the internal compensatory mechanisms that differentiate the body build and posture of people with Down syndrome (DS) from the intellectual disability (ID) population. It was assumed that gaining knowledge in the abovementioned aspect will allow for a better understanding of the limitation of the kinesthetic abilities of people with ID and DS and simultaneously enable to optimize the process of planning and interventions to improve physical activity in this population with the adequate use of theirs strengths in the biomechanical and morphofunctional systems.
METHODS: The methodology of this systematic review was developed according to the PRISMA guidelines. A search of PubMed, EBSCO, Scopus databases was conducted to identify all studies on DS/ID and the body build and posture from 2003 to 2023.
RESULTS: 395 articles were assessed to determine eligibility, while 22 studies met the inclusion criteria and were subjected to detailed analysis and assessment of their methodological quality. The differentiation of the body build and posture in DS population can be induced by both internal and external compensatory mechanisms. It is difficult to confirm the direct effect of the intrinsic variables that impact the body build and posture in the ID population, excluding people with DS.
CONCLUSIONS: Compared to other ID, the intrinsic differences in the body build and posture in DS individuals were induced by gender, age, and level of ID. The tendency for diversity between DS and other ID populations in body build and posture may be determined by the presence of the third copy of chromosome 21 in DS group. Internal compensatory processes may be induced mainly by abnormalities in the structure of the cervical vertebrae and feet. IQ should not be used as the only variable that identifies the population of people with ID.

This study aims to evaluate the relationship between breast cancer and somatotypes during early life by meta-analysis and give the corresponding advice.
Observational studies till April 5, 2021, which explore women with/without breast cancer who used the Stunkard Figure Rating Scale/Sørensen Somatotypes to evaluate their somatotype before 18 years of age and distant breast cancer risk were included. Using random/fixed-effect models, the pooled relative risks (RRs) and 95% confidence intervals (CIs) were estimated. Then a nonlinear dose-response meta-analysis was conducted using restricted cubic spline analysis.
Six articles involving 15,211 breast cancer patients from 341,905 individuals were included for performing a meta-analysis of early somatotype and breast cancer risk. The pooled results showed that the protection became stronger with the increase of somatotype until it reached 6. The restricted cubic spline model indicated a linear relationship between somatotypes and breast cancer (P-nonlinearity = 0.533). Subgroup analysis of menopausal status showed that increasing somatotype during childhood was increasingly protective against postmenopausal breast cancer from somatotype 3 to somatotype 6, with a 0.887-fold (RR = 0.887, 95% CI: 0.842, 0.934) to 0.759-fold (RR = 0.759, 95% CI: 0.631, 0.913) decreased risk of breast cancer (P-nonlinearity = 0.880), but this association was not found in the population with premenopausal breast cancer (P-nonlinearity = 0.757). When stratified by age, among people younger than 10 years of age, an increase in somatotype was associated with a statistically significant reduction in breast cancer risk. From somatotype 3 to somatotype 6, the risk of breast cancer was reduced by 9.7-27.7% (P-nonlinearity = 0.175).
With early-life adiposity, our data support an inverse association with breast cancer risk, especially age less than 10 years and in postmenopausal women. Since girls with overweight likely remain overweight or even develop obesity in adulthood. While adults with overweight and obese are at increased risk of breast cancer and other types of cancer and various chronic diseases. Hence, we recommend that children should maintain a normal or slightly fat somatotype throughout all periods of life.

The performance of male soccer players (MSP) depends on multiple factors such as body composition. The physical demands of modern soccer have changed, so the ideal body composition (BC) requirements must be adapted to the present. The aim of this systematic review and meta-analysis was to describe the anthropometric, BC, and somatotype characteristics of professional MSP and to compare the values reported according to the methods and equations used. We systematically searched Embase, PubMed, SPORTDiscus, and Web of Science following the PRISMA statement. Random-effects meta-analysis, a pooled summary of means, and 95% CI (method or equation) were calculated. Random models were used with the restricted maximum likelihood (REML) method. Seventy-four articles were included in the systematic review and seventy-three in the meta-analysis. After comparing the groups according to the assessment method (kinanthropometry, bioimpedance, and densitometry), significant differences were found in height, fat mass in kilograms, fat mass percentage, and fat-free mass in kilograms (p = 0.001; p < 0.0001). Taking into account the equation used to calculate the fat mass percentage and ∑skinfolds, significant differences were observed in the data reported according to groups (p < 0.001). Despite the limitations, this study provides useful information that could help medical technical staff to properly assess the BC of professional MSP, providing a range of guidance values for the different BC.

In addition to age-related weight gain, menopause adds additional challenges for women with the occurrence of significant metabolic alterations and central and visceral fat redistribution. The changes in body composition then influence risks of cardiovascular disease, metabolic disruption, cancer, fracture, lung disease, sexual dysfunction, mental health disorders and dementia. They may also heighten the severity of vasomotor symptoms. Treatment of these changes requires a flexible long-term strategy. This narrative review explores the pathogenesis of the metabolic changes at menopause and effective management options.

Anthropometrics are a set of direct quantitative measurements of the human body\'s external dimensions, which can be used as indirect measures of body composition. Due to a number of limitations of conventional manual techniques for the collection of body measurements, advanced systems using three-dimensional (3D) scanners are currently being employed, despite being a relatively new technique. A systematic review was carried out using Pubmed, Medline and the Cochrane Library to assess whether 3D scanners offer reproducible, reliable and accurate data with respect to anthropometrics. Although significant differences were found, 3D measurements correlated strongly with measurements made by conventional anthropometry, dual-energy X-ray absorptiometry (DXA) and air displacement plethysmography (ADP), among others. In most studies (61.1%), 3D scanners were more accurate than these other techniques; in fact, these scanners presented excellent accuracy or reliability. 3D scanners allow automated, quick and easy measurements of different body tissues. Moreover, they seem to provide reproducible, reliable and accurate data that correlate well with the other techniques used.

The present meta-analysis summarizes existing evidence on the relationship between the internalization of body shape ideals (IBSI) and body dissatisfaction.
Pooled effect sizes (r) were computed using a random-effects model. The robustness of the results was examined using influence analyses. Potential predictors of effect heterogeneity were examined using subgroup analysis and univariable/multivariable meta-regressions. Publication bias was examined using the three-parameter selection model (3PSM).
A total of 141 effect-sizes from 78 studies (N = 39,491) were retrieved. Results revealed medium (r = .25; muscular/athletic-ideal internalization) to very large (r = .43, general attractiveness-ideal internalization; and r = .45, thin-ideal internalization) relationships, all these being largely similar in male and female individuals.
IBSI and body dissatisfaction were strongly linked: (a) in younger individuals (general attractiveness-ideal internalization); (b) when IBSI was operationalized in terms of endorsement rather than mere awareness of appearance ideals; (c) in studies of lower methodological quality (muscular/athletic-ideal internalization); and (d) when IBSI was assessed using instruments involving social comparisons. Given the largely cross-sectional nature of data included in this meta-analysis, further testing in prospective and experimental studies is needed to confirm hypotheses about causality of observed associations. Such findings would have impact for prevention and intervention studies.
El presente metanálisis resume la evidencia existente sobre la relación entre la internalización de los ideales de la figura corporal (IBSI) y la insatisfacción corporal. MÉTODO: Los tamaños de los efectos agrupados (r) se calcularon utilizando un modelo de efectos aleatorios. La robustez de los resultados se examinó mediante análisis de influencia. Los predictores potenciales de heterogeneidad del efecto se examinaron mediante análisis de subgrupos y metarregresión univariable/multivariable. El sesgo de publicación se examinó mediante la inspección visual de la simetría de la gráfica de embudo y la prueba de Egger.
Se recuperó un total de 141 tamaños de efectos de 78 estudios (N = 39 491). Los resultados revelaron relaciones medias (r = .25; internalización muscular/atlética-ideal) a relaciones muy grandes (r = .43, internalización ideal de atractivo general; y r = .45, internalización delgada-ideal), siendo todas ellas en gran parte similares en individuos masculinos y femeninos. DISCUSIÓN: La Internalización de los Ideales de la Figura Ideal (IBSI) y la insatisfacción corporal fueron ligados fuertemente: (i) en individuos más jovenes (internalización atractivo-ideal general); (ii) cuando IBSI se puso en marcha en términos de aprobación en lugar de la mera conciencia de los ideales de apariencia; (iii) en estudios de menor calidad metodológica (internalización muscular/atlética-ideal); y (iv) cuando IBSI fue evaluado utilizando instrumentos que implican comparaciones sociales. Dada la gran naturaleza transversal de los datos incluidos en este metanálisis, se necesitan pruebas adicionales en estudios prospectivos y experimentales para confirmar hipótesis sobre la causalidad de las asociaciones observadas. Tales hallazgos tendrían impacto para los estudios de prevención e intervención.

The study required o apply various modes of corresponding publications search through such international databases as RussiaScopus, Web of Science, Medline, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RISC, eLIBRARY.RU. Actually, there are not less than one hundred definitions of constitution of individual. For the first time, constitutional differences were mentioned in Ayurveda. The following mentioning about constitutional types is found in the teachings of Hippocrates. The Ancient Greek philosopher Aristotle supplemented the teachings of Hippocrates. In the 18th century the somatic predispositions of the psyche were mentioned for the first time by J.-A. de La Mettrie. However, the systemic study of constitutional characteristics begins only in the 19th century. In the 20th century, the constitutional characters of human began to be associated with such clinical science as psychiatry. In the mid-30s of the 20th century acquires significance the classification of types approved by I. P. Pavlov. After Pavlov\'s theory, numerous works begin to appear where attempts are made to determine the main somatotypic reactions of individuals (V. B. Shtefko, A. D. Ostrovsky, V. N. Shevkunenko). In 1929, V. N. Shevkunenko, the outstanding Leningrad scientist, developed the classification that was lead as foundation of the theory of W. H. Sheldon (1940, 1942). Approximately in the same time period (1941) the Russian researcher V. V. Bunak develops criterion estimated indices of classification for males. In the end of 20th century classifications by B. Heath and L. Carter, V. P. Chtetsov, R. N. Dorokhov, V. G. Petrukhin, A. V. Kondrashov acquire great reputation. In the 21st century, the methods directed to biologically differential indices lined up with consideration of medical individual indices of body mass and body length are developed. Nowadays, despite of enormous number of methods, the universal criteria for somatotyping are to be developed.

BACKGROUND: Published studies have shown contradictory results regarding the relationship between somatometric parameters and varicoceles. We performed a systematic review and meta-analysis to investigate the possible effects of age, height, weight, and body mass index (BMI) on the presence and severity of varicoceles.
METHODS: Databases including EMBASE, MEDLINE, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Web of Science, and Google Scholar were systematically searched to identify relevant articles published up to March 2020. Two researchers independently identified eligible articles and extracted data. Cochran\'s Q statistic and I2 statistics were used to assess heterogeneity. Meta-analysis was performed using StataSE 12.0 software (StataCorp LP, USA). Random-effects models were used to obtain the weighted mean differences (WMDs) and 95% confidence intervals (CIs). Publication bias was assessed using Begg\'s funnel plot and Egger\'s regression test.
RESULTS: The search strategy produced 272 articles, of which 18 articles were eligible according to the inclusion/exclusion criteria. A total of 56,325 patients with varicocele and 1,334,694 patients without varicocele were included in the meta-analysis to evaluate the effect of somatometric parameters on the presence and severity of varicocele. The overall results demonstrated that the presence of varicoceles was significantly associated with height (WMD = 1.41, 95% CI = 1.07 to 1.74, P < 0.001) and inversely correlated with BMI (WMD = - 1.35, 95% CI = -1.67 to - 1.03, P < 0.001) but not with age (WMD = -0.93, 95% CI = -2.19 to 0.33, P = 0.149) or weight (WMD = 0.24, 95% CI = -2.24 to 2.72, P = 0.850). The severity of varicocele was inversely correlated with increased BMI but not with age.
CONCLUSIONS: The presence of varicoceles was significantly associated with height and inversely correlated with BMI.

BACKGROUND: The aim of the present systematic review was to profile soccer players\' anthropometric, physiological, and physical attributes relative to different competitive levels, playing positions and age groups.
METHODS: The systematic search was conducted using different databases and according to the Population/Intervention or Exposure/Comparison/Outcome(s) [PICO] criteria.
RESULTS: The present review shows that the somatotype characteristics, percentage (%) of body fat, maximal oxygen uptake (VO2max), repeated-sprint ability (RSA), running speed, strength, and muscular power of the lower limbs were the most powerful discriminators between male soccer players of different competitive levels, playing positions, and age groups. Specifically, higher VO2max, muscle strength, muscular power (vertical jump height), running speed (10-30 m) and agility, and lower % of body fat were identified in elite soccer players (higher-level) compared to all other competitive levels (i.e., lower-level: sub-elite, amateur, recreational). As for the competitive level differences, higher VO2max, mean anaerobic power, RSA and sprint performances (5 to 20 m), and lower % of body fat and lower limbs\' explosive capabilities (countermovement jump [CMJ] and squat jump [SJ]) were found in outfielders (forwards, midfielders, and defenders) as compared to goalkeepers, from a very youth age (8 years old). Concerning age-related performance, it appears that physical performance increased significantly with age.
CONCLUSIONS: These data, together with the fact that each position, age category, and playing level has a different physiological background in male soccer players, demonstrate that training programs should be individualized to each position, playing level and age category, as is already done with goalkeepers.

We describe a case report of a 30-year-old bodybuilder suffering acute myocardial infarction (AMI). He had been taking stanozolol and testosterone for two months. The coronary angiogram showed high thrombotic burden in the left anterior descending artery without underlying atherosclerosis. Few case reports of AMI in athletes taking anabolic androgenic steroids (AASs) have been reported so far. AAS-related AMI is possibly underreported in the medical literature due to the desire of the affected individuals to hide AAS use. Physicians should always consider the possibility of AAS abuse in the context of a young athlete suffering AMI. AASs can predispose to AMI through the acceleration of coronary atherosclerosis. Additionally, thrombosis without underlying atherosclerosis or vasospasm is highly possible to cause AMI in AAS users. Complications after AMI may be more frequent in AAS users.