Solid

固体
  • 文章类型: Journal Article
    简介:牙源性肿瘤包括一组异质性病变,范围从错构瘤性病变到恶性肿瘤。组织学表现的显着变化可能会误导其准确的诊断和分类。成釉细胞瘤通常很容易理解并且易于诊断,但是自从Broca在1867年对牙源性肿瘤进行分类以来,分类系统一直在变化。多年来,它已被世界卫生组织修改,有许多补充和遗漏。这种动态变化是基于分子和遗传研究的结果和结论,最后一次修改是在2017年。病例报告:我们介绍了2例32岁和60岁女性报告面部肿胀,显示存在明显的组织病理学发现,并被诊断为成釉细胞瘤伴有牙样或腺样成釉细胞瘤。文献检索显示缺乏不同形式的成釉细胞瘤,这些成釉细胞瘤显示形成导管样结构和牙质。结论:由于缺乏相关研究和对患者的随访,生物学行为仍未被探索,因此强调此类病例很有趣。了解新实体的发病机制和组织病理学特征将有助于及时诊断,治疗计划和扩大病变范围。
    在线版本包含补充材料,可在10.1007/s12070-023-03534-6获得。
    Introduction: Odontogenic tumors encompass a heterogeneous group of lesions that range from hamartomatous lesions to malignancy. Considerable variation in histologic presentation can mislead their accurate diagnosis and categorization. Ameloblastoma is generally well understood and is easy to diagnose but there has been a constant change in the classification systems ever since Broca classified odontogenic tumors in the year 1867. Over the years, it has been modified by the World Health Organization with many additions and omissions. This dynamic change is based on the result and conclusions of molecular and genetic studies with the last modification in 2017. Case Report: We present two cases of females aged 32 and 60 years who reported with facial swellings, revealed the presence of distinct histopathological findings and were diagnosed as ameloblastoma with dentinoid or adenoid ameloblastoma. Literature search revealed dearth of distinct forms of ameloblastoma that show the formation of duct like structures and dentinoid. Conclusion: It is interesting to highlight such cases as the biological behavior is still unexplored due to paucity of relevant studies and follow up of patients. Understanding the pathogenesis and the histopathological characteristics of the newer entities will enable the prompt diagnosis, treatment plan and expanding the spectrum of the lesions.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-023-03534-6.
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  • 文章类型: Journal Article
    这篇重要评论涵盖了通过同步荧光光谱法(SFS)及其品种分析不同类型的固体样品的文献报告,其中包括同步磷光光谱和同步发光光谱,在这三十年(1990-2019年)。定性和定量光谱分析都描述了广泛的标本。它们的物理形式和化学组成包括:a)从基质上的溶液中预浓缩的有机和无机分析物(珠子,膜,过滤器,磁盘,paper),b)复杂成分的天然和合成多组分标本(生物组织,土壤,聚合物)和c)无机和配位化合物,包括多孔材料,特别是金属有机骨架(MOF)。提供了与通过“常规”光学发射光谱法和其他分析技术(如果可用)获得的数据的比较。该方法的高分辨率品种的具体优势,一阶和二阶导数固态同步荧光,发光,和磷光光谱进行了描述。还注意典型测试的实际情况,以及相关的实验设置。动力是这种非常有前途的方法的新兴能力,例如化学反应的原位监测,体内诊断,表面反应,和吸附物的检测。分析了现有的挑战,并揭示了进一步发展这一点的未探索应用“利基”和相关的分析方法。145个参考文献,9表,17个数字和1个方案。
    This critical Review covers the literature reports on analysis of different types of solid samples by the synchronous fluorescence spectroscopy (SFS) and its varieties, which include synchronous phosphorescence spectroscopy and synchronous luminescence spectroscopy, in the three decades (1990-2019). Both the qualitative and quantitative spectroscopic analysis is described for a wide range of specimens. Their physical forms and chemical composition include: a) organic and inorganic analytes pre-concentrated from solution on matrices (beads, membranes, filters, disks, paper), b) natural and synthetic multi-component specimens of complex composition (biological tissues, soil, polymers) and c) inorganic and coordination compounds including porous materials and particularly metal-organic frameworks (MOFs). The comparison with the data obtained by \"conventional\" optical emission spectroscopy and other analytical techniques (when available) is presented. The specific advantages of the high-resolution varieties of the method, the first- and second-derivative solid-state synchronous fluorescence, luminescence, and phosphorescence spectroscopy are described. An attention is also paid to practical conditions of the typical tests, and the relevant experimental setups. The impetus is on the emerging capabilities of this highly promising method e.g. in-situ monitoring of chemical reactions, in-vivo diagnostics, surface reactions, and detection of the adsorbate. The existing challenges are analyzed, and the unexplored application \"niches\" to further develop this and the related analytical methods are revealed. 145 references, 9 Tables, 17 Figures and 1 Scheme.
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  • 文章类型: Journal Article
    实体乳头状癌(SPC)是一种罕见的乳腺肿瘤,其预后取决于浸润性成分。我们回顾了65例SPC的临床病理特征。75.4%的病例可见侵入性成分。几乎所有具有III级核的肿瘤都具有侵袭性成分。浸润性肿瘤患者的平均年龄明显高于非浸润性肿瘤(P=0.036)。除一名发生远处转移并死于疾病的患者外,所有患者均存活且无疾病。SPC具有良好的临床病程。仔细检查侵入性组件是强制性的,尤其是患者年龄较大、核级别较高的肿瘤。
    Solid papillary carcinoma (SPC) is an uncommon breast tumor whose prognosis depends on invasive component. We studied clinicopathological features of SPC by reviewing 65 cases. Invasive component was seen in 75.4% cases. Almost all tumors with grade III nuclei had invasive component. Mean patients\' age of invasive tumors was significantly higher than that of non-invasive tumors (P = .036). All patients were alive and disease free except for a single patient who developed distant metastasis and died of disease. SPC have excellent clinical course. Careful search for invasive component is mandatory, especially in tumors with older patient\'s age and higher nuclear grade.
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  • 文章类型: Journal Article
    Bacillus species are known to cause severe infection in immunocompromised hosts. The incidence of Bacillus bloodstream infections and characteristics of infection among children with cancer or indication for hematopoietic cell transplant (HCT) is unknown.
    We performed a retrospective medical record review of all cases of Bacillus bacteremia between January 1, 2005, and December 31, 2014, at Boston Children\'s Hospital. We report average incidences from 2012 to 2014. We performed a detailed review of infections among children with cancer or undergoing HCT and a case-control study to evaluate whether neutropenia at diagnosis caries higher risk of Bacillus infection for children with acute lymphoblastic leukemia (ALL).
    One hundred fourteen children developed Bacillus bacteremia during the study period, with an estimated incidence of 0.27/1,000 patients. Among children treated for cancer or undergoing HCT, there were 37 bloodstream infections (2.0/1,000 patients). Of the 37 oncology/HCT patients, oncologic diagnoses included ALL (18), acute myeloid leukemia (3), myelodysplastic syndrome (1), solid tumors (8), and 7 children were undergoing HCT. The incidence of infection among children with ALL was 34/1,000 patients and all central nervous system (CNS) infections (6) and deaths (3) occurred in this population. Neutropenia at time of diagnosis in children with ALL was not associated with risk of infection (P = 0.17).
    We report the first hospital-wide analysis of Bacillus infection and found that immunocompromised children experience a significant proportion of Bacillus infections. Children with ALL have a high incidence of infection and are at higher risk of CNS involvement and death.
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  • 文章类型: Journal Article
    Solid variant papillary thyroid carcinoma (SVPTC) is a rare variant of papillary thyroid cancer (PTC) and its prognostic value is still unclear. The purpose of this systematic clinical review and meta-analysis is to investigate the prognostic value of SVPTC in comparison with classical PTC (cPTC).
    Four electronic databases, including PubMed, Scopus, Web of Science, and Virtual Health Library, were searched in June 2017. Extracted data were pooled into odds ratio (OR) or hazard ratio (HR) and their corresponding 95% confidence interval (CI) using the random-effect model.
    From 1439 articles, we finally included 11 studies with 205 SVPTCs for meta-analysis. Overall, SVPTC manifested a significantly higher risk for vascular invasion, tumor recurrence, and cancer mortality as compared to cPTC. The genetic profile of SVPTC was also distinct from that of cPTC.
    A case of SVPTC should be regarded as an aggressive variant of PTC because of a higher risk for tumor recurrence and mortality.
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  • 文章类型: Journal Article
    Solid pseudopapillary tumors (SPTs) of the pancreas are a rare occurrence, not exceeding 1-2% of all exocrine pancreatic tumors. SPT was first described in 1959 as \"papillary tumor of the pancreas, benign or malignant\" and affects mainly young women, in their second or third decade of age. These tumors are of low malignant potential, unclear pathogenesis, grow gradually and become considerably large before causing symptoms. A typical clinical presentation is often described by affected patients and, in some cases, an SPT is an incidental finding during the time the patient undergoes medical imaging studies for other health issues. SPT is frequently located at the head or tail of the pancreas. Metastases are rare but, when present, affect predominantly the liver.
    We report a series of five SPT cases in female patients 13-47 years old, presenting with almost identical symptoms of upper abdominal discomfort and non-tender palpable mass. Two out of five patients also reported vomiting, nausea and poor appetite as co-existing non-diagnostic symptoms. Only one patient presented without any symptoms. Tumor location and dimensions varied. One patient underwent a pancreatoduodenectomy (Whipple\'s procedure), while the remaining patients underwent distal pancreatectomy with concomitant splenectomy.
    Perioperative morbidity and mortality was zero. All five patients are disease-free at a follow-up from 3 months to 13 years. Histopathology reports supported the diagnosis of SPT and no metastatic disease was present in any of the patients.
    The overall prognosis of SPT of the pancreas is excellent due to its favorable biological features, even in the presence of distal metastasis. Although surgical resection is often curative, a close follow-up is advised in order to diagnose a possible local recurrence or distal metastasis and choose the proper therapeutic option for the patients.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    BACKGROUND: Solid-cystic pseudopapillary tumor of the pancreas is rare and most commonly seen in young women. We present a young women with solid-cystic pseudopapillary tumor of the pancreas and discuss the literature.
    METHODS: Thirty nine years old female patient with a mass about 12cm in the pancreas with splenic invasion seen in our clinic. After having CT and PET-CT view, patient underwent surgery. Distal pancreatectomy with mass excision and splenectomy was performed. Microscopic examination result was solid cystic pseudopapillary tumor with spleen invasion.
    CONCLUSIONS: Solid-cystic pseudopapillary tumor of the pancreas has cystic solid pseudopapillary structures. Prognosis of tumor is better than other pancreatic tumor. Complete resection of tumor with splenic inclusion is surgical treatment.
    CONCLUSIONS: In case of large slow growing pancreatic tumor with splenic metastasis, solid-cystic pseudopapillary tumor of the pancreas should be considered in the diagnosis. Complete surgical resection is associated with long-term survival even in the presence of metastatic disease. Close follow-up is necessary after surgery.
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