BACKGROUND: Effective emotional regulation (ER) skills are important for sexual function, as they impact emotional awareness and expression during sexual activity, and therefore, satisfaction and distress. Emotion regulation interventions may offer a promising approach to improve sexual health. Web-based emotion regulation may be a therapeutic strategy for men and women with sexual health concerns. Nevertheless, there is a scarcity of intervention trials investigating its effects in this context, much less using the internet.
OBJECTIVE: This study aims to investigate the effects of a web-based emotion regulation training program for sexual function in both men and women.
METHODS: The participants were recruited based on their self-reported sexual problems, which for men was defined by a score of <25 on the International Index Erectile Function (IIEF) and for women by a score of <26.55 on the Female Sexual Function Index (FSFI). The final sample included 60 participants who were randomized to either a web-based emotion regulation training for sexual function or to a waitlist control group. The treatment consisted of an 8-week web-based emotion regulation training for sexual function. The participants were assessed at baseline, post intervention, and the 3-month follow-up.
RESULTS: Of the 60 participants included, only 6 completed all 3 assessment points (n=5, 20% in the treatment group and n=1, 5% in the waitlist control group) after receiving the intervention. At follow-up, there were no significant differences between groups in any measure. Among the intervention completers, large-to-moderate within-group effect sizes were observed between the assessment points on measures of emotion regulation, depression, lubrication, orgasm, thoughts of sexual failure, and abuse during sexual activity. The adherence rate was very low, limiting the generalizability of the findings.
CONCLUSIONS: Participants who completed the intervention showed improvements in both sexual function domains and emotion regulation. Nonetheless, due to a high dropout rate, this trial failed to collect sufficient data to allow for any conclusions to be drawn on treatment effects.
BACKGROUND: ClinicalTrials.gov NCT04792177; https://clinicaltrials.gov/study/NCT04792177.

Female sexual dysfunction (FSD) has a negative impact on women\'s quality of life, self-esteem, and physical health. The aim of the present study was to explore the prevalence and the factors associated with FSD using an online questionnaire. A cross-sectional survey was conducted among young adults (18-35 years old) in Hungary using the DSM-5 criteria. The participants (n = 5942) were divided into three major groups: FSD (20.3%), an intermediate group (43.9%), and a control group (35.6%). Most of the women showing FSD were affected with female orgasmic disorder (9.2%) and genito-pelvic pain/penetration disorder (4.6%), while female sexual interest/arousal disorder was found in altogether 100 women (1.7%); 4.8% of women were affected by more than one definite disorder. The occurrence of female sexual dysfunction was related to the women\'s previous sexual history (first sexual experience, sexual education, early encounter with pornographic content, and sexual abuse), their self-satisfaction (with their own body, genitalia, and sexual attraction), and their sexual orientation. Sexual dysfunction showed a strong association with abuse, sexually transmitted diseases, and self-esteem. The present study identified the relationship between sexual dysfunctions and other health conditions, which can be the basis for some form of screening and early assistance programs for FSD.

Introduction and Hypothesis Female urinary incontinence (UI) has a negative impact on sexual function and sexual quality of life (QoL) in women. But there is still no consensus on the type of UI or the prevalence of sexual dysfunction (SD). The aim of the study was to evaluate sexual disorders in women with overactive bladder (OAB) compared to patients with urinary stress incontinence (SUI) and healthy controls. Materials and Methods 106 women presenting to a urogynecological outpatient clinic (referral clinic) were investigated using standardized questionnaires and the Female Sexual Function Index (FSFI-d). All 65 incontinent women underwent a full urodynamic examination; the controls (31) were non-incontinent women in the same age range who came for routine check-ups or minor disorders not involving micturition or pelvic floor function. Women with mixed urinary incontinence, a history of previous medical or surgical treatment for UI, recurrent urinary tract infections, previous radiation therapy or pelvic organ prolapse of more than stage 2 on the Pelvic Organ Prolapse Quantification (POP-Q) system were excluded. Results 100 questionnaires could be evaluated (94.3%). Thirty-four women had urinary stress incontinence, 35 had OAB, 31 were controls. Mean age was 56 years, with no significant differences between groups. The scores of the questionnaire ranged from 2 to 35.1 points. The median score of OAB patients was significantly lower (17.6) than the median score of the controls (26.5; p = 0,004). The stress-incontinent women had a score of 21.95, which was lower than that of the controls but statistically non-significant (p = 0.051). In all subdomains, the OAB patients had lower scores than the stress-incontinent women and significantly lower values than the control group. Most striking was the impairment of \"sexual interest in the last 4 weeks\". The figure for \"none or almost no sexual activity\" was 80% for the OAB group, 64.7% for the group of stress-incontinent women and 48% for the control group. Incontinence during intercourse was reported by one OAB patient and 4 stress-incontinent women but did not occur in the control group. Conclusions There is a high prevalence of SD in women with urinary incontinence. Patients with OAB reported a greater negative impact on sexual function and had significantly lower scores for the FSFI questionnaire than patients with stress incontinence or controls.
Einleitung und Hypothese Die weibliche Harninkontinenz wirkt sich negativ auf die Sexualfunktion und die sexuelle Lebensqualität von betroffenen Frauen aus. Aber es herrscht immer noch kein Konsens über die Auswirkungen der Art der Harninkontinenz auf die Prävalenz von sexuellen Funktionsstörungen. Ziel dieser Studie war es, sexuelle Funktionsstörungen bei Frauen mit überaktiver Blase zu evaluieren im Vergleich zu Patientinnen mit Stressharninkontinenz sowie einer gesunden Kontrollgruppe. Material und Methoden 106 Frauen, die an eine urogynäkologische Ambulanz überwiesen wurden, wurden mithilfe standardisierter Fragebögen und der deutschsprachigen Fassung des Female Sexual Function Index (FSFI-d) untersucht. Bei allen 65 inkontinenten Frauen wurde eine vollständige urodynamische Untersuchung durchgeführt, die Kontrollgruppe (31) bestand aus nicht inkontinenten Frauen desselben Alters, die sich wegen einer Routineuntersuchung oder kleineren Beschwerden, die nicht im Zusammenhang mit Harnentleerung oder Beckenbodenfunktion standen, vorstellig wurden. Frauen mit gemischter Harninkontinenz, medizinischen oder chirurgischen Inkontinenzbehandlungen in der Anamnese, wiederholten Harntraktinfekten, einer früheren Radiotherapie oder einem Beckenorganvorfall von mehr als Stadium II (bewertet mit dem [POP-Q] Beckenorgan-Prolaps-Quantifizierungssystem) wurden nicht in die Studie aufgenommen. Ergebnisse Es konnten insgesamt 100 Fragebogen evaluiert werden (94,3%). 34 Frauen litten an Belastungsharninkontinenz, 35 hatte eine überaktive Blase/Dranginkontinenz, 31 Frauen dienten als Kontrollgruppe. Das mittlere Alter betrug 56 Jahre, und es gab keine signifikanten Unterschiede zwischen den Gruppen. Die erzielte Punktzahl für den Fragenbogen reichte von 2 bis 35,1 Punkten. Die Durchschnittswerte der Patientinnen mit überaktiver Blase waren signifikant niedriger (17,6) als die durchschnittliche Punktzahl der Kontrollgruppe (26,5; p = 0,004). Die Punktzahl der Gruppe mit Belastungsharninkontinenz betrug 21,95, was auffällig war im Vergleich zur Kontrollgruppe. Trotzdem war dieser Unterschied nicht statistisch signifikant (p = 0,051). Patientinnen mit überaktiver Blase wiesen in allen Teilbereichen geringere Werte als Frauen mit Belastungsharninkontinenz und signifikant niedrigere Werte als die Kontrollgruppe auf. Am auffälligsten war die Beeinträchtigung von „sexuellem Interesse in den vergangenen 4 Wochen“: 80% der Patientinnen kreuzten „keine oder fast keine sexuelle Aktivitäten“ an, bei Frauen mit Belastungsharninkontinenz waren es 64,7% und bei der Kontrollgruppe 48%. Eine Patientin mit überaktiver Blase und 4 der Frauen mit Belastungsharninkontinenz, aber keine der Frauen in der Kontrollgruppe vermeldeten Inkontinenz während des Geschlechtsverkehrs. Schlussfolgerungen Obwohl es eine hohe Prävalenz an sexuellen Funktionsstörungen bei Frauen mit Harninkontinenz gab, wiesen Patientinnen mit überaktiver Blase eine stärkere negative Auswirkung auf die Sexualfunktion auf und hatten signifikant niedrigere Werte beim FSFI-Fragenbogen als Frauen mit Belastungsharninkontinenz oder Frauen aus der Kontrollgruppe.

BACKGROUND: Hypoactive Sexual Desire Disorder (HSDD) is a common sexual problem of women which has negative impacts on their health and quality of life. Given the side effects of pharmacologic interventions, it would be beneficial to patients trying to find new options based on herbal medicine.
OBJECTIVE: To evaluate efficacy of carrot seed on sexual dysfunction of women with HSDD compared with placebo.
METHODS: In this randomized double-blind clinical trial, 68 participants randomly assigned to the intervention group which took 500 mg carrot seed three times a day for 12 weeks versus placebo. Participants in two groups filled Female Sexual Function Index (FSFI) questionnaire at baseline, week six and 12. Repeated measure analysis of variance (ANOVA) test was used for statistical analysis.
RESULTS: Thirty women in carrot seed group and thirty women in placebo group completed 12 weeks of the study. In general, carrot seed compared to placebo improved the total score of FSFI 7.329 ± 0.830 (p < 0.001), desire 4.1±0.7 (p < 0.001), lubrication 4.7±0.4 (p = 0.019), arousal 4.1±0.08 (p < 0.001), satisfaction 4.8±1.1 (p < 0.001), orgasm 3.9±0.9 (p < 0.001) and pain 5.4±1(p < 0.001). No adverse event was reported in this study.
CONCLUSIONS: Women with HSDD may benefit from six weeks\' treatment with carrot seed for improvement of sexual dysfunction. Further large clinical studies are warranted to confirm efficacy of this herbal drug.

BACKGROUND: Sexual dysfunction (SD) is a stressful and common symptom in women with multiple sclerosis (MS) and affects different aspects of their life, seriously. The purpose of this study was to determine the prevalence, dimensions, and predictor factors of SD in Iranian women with MS.
METHODS: This cross-sectional study was conducted in Iran MS Society. Participants were 260 married women who had definite MS. Data were collected using self-report questionnaires, including Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 (MSISQ-19); Fatigue Severity Scale (FSS); Depression, Anxiety, and Stress Scale-21 (DASS-21); Questionnaire for Urinary Incontinence Diagnosis (QUID); ENRICH Marital Satisfaction Scale (EMS); Sexual Self-Efficacy Questionnaire; and socio-demographic and disease information questionnaire. Pearson correlation coefficients, independent sample t-test, one-way analysis of variance (ANOVA), and multiple linear regression model were used for data analysis.
RESULTS: Majority (76.2%) of the participants had SD, and according to the dimensions of SD in MS, primary SD was found in 176 (67.7%), secondary SD in 158 (60.7%), and tertiary SD in 126 (48.5%) of the participants. The most important and common problem was delayed orgasm (60%). According to the results of multiple linear regression model, the predictor factors of SD were sexual self-efficacy (B = -0.721, P < 0.001), disability status (B = 2.714, P < 0.001), urge incontinence (B = 0.367, P = 0.029), depression (B = 0.446, P = 0.007), anxiety (B = 0.332, P = 0.037), fatigue (B = 0.177, P = 0.002), duration of disease (B = -0.463, P = 0.014), and duration of DMT use (B = 0.662, P = 0.002).
CONCLUSIONS: According to the results of this cross-sectional study, SD was a very common and complex problem in women of Iran MS Society, and a number of physical, neurological, and psychological factors, such as sexual self-efficacy, disability status, urge incontinence, depression, anxiety, fatigue, duration of DMT use, and duration of disease, play a role in SD of these patients. So, in the treatment procedure of SD in MS women, adopting a multidisciplinary approach, as well as considering all contributory factors and their impact on sexual function, is recommended.