目的:比较上前庭神经炎(SVN)患者与一般法国人群中心血管危险因素(CVRF)的患病率,并检查急性前庭上缺损血管病因的可能性。
方法:一项单中心回顾性研究比较了高胆固醇血症的患病率,高血压,糖尿病,吸烟,SVN患者与法国普通人群之间的心血管疾病和心房颤动。纳入标准包括:持续数天的旋转性眩晕,没有听力损伤或神经体征,视频头部脉冲测试(vHIT)上的前半规管和外侧半规管受累。一位高级放射科医生在桥小脑MRI上分析了前庭上神经和内耳结构的增强。
结果:纳入2016年5月至2020年2月的118例SVN。统计分析涉及106例。SVN人群的高胆固醇血症(RR=0.40)明显少于法国普通人群。其他CVRF无显著差异。在84%的MRI上观察到前庭上神经增强。
结论:SVN患者的CVRF患病率并不高于一般人群。本研究强调了SVN中前庭上神经的受累多于前庭前动脉的受累。
OBJECTIVE: To compare the prevalence of cardiovascular risk factors (CVRF) in patients with superior vestibular neuritis (SVN) versus the general French population, and to examine the possibility of vascular etiology in acute superior vestibular deficit.
METHODS: A single-center retrospective study compared the prevalence of hypercholesterolemia, hypertension, diabetes, smoking, cardiovascular disease and atrial fibrillation between patients with SVN and the French general population. Inclusion criteria comprised: rotatory vertigo lasting several days, without hearing impairment or neurological signs, with anterior and lateral semicircular canal involvement on video-Head-Impulse-Test (vHIT). A senior radiologist analyzed superior vestibular nerve and inner ear structure enhancement on cerebellopontine MRI.
RESULTS: One hundred and eighteen cases of SVN were included from May 2016 to February 2020. Statistical analyses concerned 106 cases. The SVN population had significantly less hypercholesterolemia (RR=0.40) than the general French population. There was no significant difference concerning other CVRFs. Superior vestibular nerve enhancement was observed on 84% of MRIs.
CONCLUSIONS: Prevalence of CVRF was not higher in patients with SVN than in the general population. The present study highlighted involvement of the superior vestibular nerve more than of the anterior vestibular artery in SVN.