SLA

SLA
  • 文章类型: Journal Article
    随着复杂动态系统理论(CDST)在第二语言问题(SLA)领域的出现,与以前相比,人们越来越需要合适的CDST兼容方法来研究L2情感变量的时间变化。为此目的的创新方法之一是潜在增长曲线建模(LGCM),最近引起了SLA学者的注意。然而,这种方法的应用在SLA中仍然是一个新兴的需求。为了响应这一需求,本研究对概念化进行了回顾,意义,以及LGCM实现的技术特点。在这样做的时候,这篇综述提出了一些在SLA中引入LGCM的实践。此外,为SLA研究人员提高LGCM素养提供了一些实际意义。最后,讨论了该方法在SLA中的使用进展的未来研究建议。
    With the advent of Complex dynamic systems theory (CDST) in the field of second language question (SLA), the need for suitable CDST compatible methods for the investigation of temporal change in L2 affective variables has been felt more than before. One of the innovative methods for this purpose is latent growth curve modeling (LGCM), which has recently drawn the attention of SLA scholars. However, the application of this method is still a burgeoning demand in SLA. In response to this demand, the present study provides a review of the conceptualization, significance, and technical features of the implementation of LGCM. In doing so, this review suggests a number of practices via which LGCM has been introduced in SLA. Additionally, some practical implications are provided for SLA researchers to enhance their literacy of LGCM. Finally, future research suggestions for the progress of the use of this method in SLA are discussed.
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  • 文章类型: Journal Article
    增材制造(3D打印)在技术方面极大地改变了原型制作过程,建筑,材料,以及它们的多物理性质。其中最流行的3D打印技术是大桶光聚合,其中紫外线(UV)光被部署以在液体光固化树脂分子之间形成链,将它们交联,结果,固化树脂。在这份手稿中,三种光聚合技术,即,立体光刻(SLA),数字光处理(DLP),和连续数字光处理(CDLP),被审查。此外,列出了光固化树脂材料的固化后机械性能,以及一些展示它们在实践中应用的案例研究。该手稿旨在提供光聚合技术的概述和未来趋势,以激发读者在该领域的进一步研究,特别是关于开发新材料和微棒和仿生结构的数学模型。
    Additive manufacturing (3D printing) has significantly changed the prototyping process in terms of technology, construction, materials, and their multiphysical properties. Among the most popular 3D printing techniques is vat photopolymerization, in which ultraviolet (UV) light is deployed to form chains between molecules of liquid light-curable resin, crosslink them, and as a result, solidify the resin. In this manuscript, three photopolymerization technologies, namely, stereolithography (SLA), digital light processing (DLP), and continuous digital light processing (CDLP), are reviewed. Additionally, the after-cured mechanical properties of light-curable resin materials are listed, along with a number of case studies showing their applications in practice. The manuscript aims at providing an overview and future trend of the photopolymerization technology to inspire the readers to engage in further research in this field, especially regarding developing new materials and mathematical models for microrods and bionic structures.
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  • 文章类型: Journal Article
    背景:激光间质热疗(LITT;也称为立体定向激光消融或SLA),是一种微创治疗方式,最近在恶性原发性和转移性脑肿瘤和放射性坏死的治疗中得到了重视,并且最近已经报道了治疗脊柱转移的研究。
    方法:在这里,我们提供了LITT的各种当代用途及其报告结果的简要文献综述。
    结果:历史上,LITT的主要适应症是治疗复发性胶质母细胞瘤(GBM).然而,适应症不断扩大,现在包括不同等级的神经胶质瘤,脑转移瘤(BM),放射性坏死(RN),其他类型的脑肿瘤以及脊柱转移瘤。LITT正在成为保险箱,可靠,微创临床方法,特别是对于深层的,局灶性恶性脑肿瘤和放射性坏死。LITT在治疗其他类型的脑肿瘤和脊柱肿瘤中的作用似乎在少数中心发展。虽然这项技术似乎是安全的,并且越来越多地使用,很少有前瞻性临床试验,大多数已发表的研究在同一份报告中结合了不同的病理。
    结论:需要精心设计的前瞻性试验来牢固地确立LITT在脑和脊柱病变治疗中的作用。
    BACKGROUND: Laser Interstitial Thermotherapy (LITT; also known as Stereotactic Laser Ablation or SLA), is a minimally invasive treatment modality that has recently gained prominence in the treatment of malignant primary and metastatic brain tumors and radiation necrosis and studies for treatment of spinal metastasis has recently been reported.
    METHODS: Here we provide a brief literature review of the various contemporary uses for LITT and their reported outcomes.
    RESULTS: Historically, the primary indication for LITT has been for the treatment of recurrent glioblastoma (GBM). However, indications have continued to expand and now include gliomas of different grades, brain metastasis (BM), radiation necrosis (RN), other types of brain tumors as well as spine metastasis. LITT is emerging as a safe, reliable, minimally invasive clinical approach, particularly for deep seated, focal malignant brain tumors and radiation necrosis. The role of LITT for treatment of other types of tumors of the brain and for spine tumors appears to be evolving at a small number of centers. While the technology appears to be safe and increasingly utilized, there have been few prospective clinical trials and most published studies combine different pathologies in the same report.
    CONCLUSIONS: Well-designed prospective trials will be required to firmly establish the role of LITT in the treatment of lesions of the brain and spine.
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  • 文章类型: Journal Article
    BACKGROUND: The optimal treatment of brain metastases recurring after radiosurgery (BMRS) remains an area of active investigation. Stereotactic laser ablation (SLA, also known as laser interstitial thermal therapy) has recently emerged as a potential treatment option.
    OBJECTIVE: To summarize the available literature on SLA as treatment of BMRS and synthesize findings on local control, overall survival, neurologic outcome, imaging findings, morbidity, and postprocedure clinical course.
    METHODS: We performed a comprehensive search of PubMed for articles investigating SLA as treatment of BMRS.
    RESULTS: Thirteen peer-reviewed publications met our search criteria. Local control was a function of the percentage of tumor that was thermally ablated. In completely ablated tumors, 3-month local control was 80%-100%. Median survival ranged from 5.8 to 19.8 months. About two-thirds of treated lesions showed postablation expansion of contrast-enhancing volume and fluid-attenuated inversion recovery volume. Expansion could start within an hour of treatment, and resolution typically occurred within 6 months. Notably, maximal expanded contrast-enhancing volume could reach >3-fold the preoperative lesion volume. The incidence of SLA-related permanent neurologic injuries was <10%. The most common complications were hemorrhage, thermal injury causing neurologic deficit, and malignant cerebral edema. Nearly all patients were treated with dexamethasone, but there was variability in the dose and duration of therapy. Median hospital stay was 1-2 days (range, 1-5 days), and most treated patients were discharged home (range, 59.5%-100%).
    CONCLUSIONS: Our analysis provides support for continued development of SLA as a treatment of BMRS. Standardization of periprocedural management will be needed.
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