背景:细菌及其副产物是髓根尖周病发病和延续的关键贡献者。肛门内药物治疗对于实现成功的牙髓治疗结果至关重要,因为它可以靶向并根除生物力学制备后残留的微生物。
目的:本研究的目的是比较和评估氢氧化钙(CH)糊剂的抗菌功效,三重抗生素糊剂(TAP),和益生菌(PBs)作为肛门内药物在12-17岁的儿童中接受根管治疗,以管理年轻恒牙中感染的牙髓组织。
方法:选择30例上颌切牙牙髓治疗患者,年龄12-17岁,无全身并发症。他们被随机分为三组,即,I组-CH组,第二组-TAP,第III组-PB每组分配10颗牙齿。进入后,通过将纸点插入根管来收集第一个样本(S1),在生物力学制备后立即收集第二个样品(S2),7天后收集第三个样本(S3),即,肛门内用药。样本被送去进行微生物分析以评估微生物计数,并对所得数据进行统计分析。
结果:三种管内药物成功地减少了感染根管中粪肠球菌的微生物计数。然而,根据研究结果,与CH组相比,PB组表现出更高的抗粪肠球菌效力,并表现出与TAP组相似的抗微生物效力.
结论:PB表现出与TAP相当的抗菌功效,但高于Ca(OH)2糊剂。因此,PB可以用作年轻恒牙的肛门内药物。
BACKGROUND: Bacteria and their byproducts are key contributors to the onset and perpetuation of pulpoperiapical pathosis. Intracanal medication is vital in achieving successful endodontic outcomes as it targets and eradicates remaining microorganisms following biomechanical preparation.
OBJECTIVE: The aim of the
study was to compare and evaluate the antimicrobial efficacy of calcium hydroxide (CH) paste, triple antibiotic paste (TAP), and probiotics (PBs) as intracanal medicament in 12-17-year-old children undergoing root canal treatment for the management of infected pulpal tissues in young permanent teeth.
METHODS: A total of 30 patients aged 12-17 years indicated for endodontic therapy in maxillary incisors and with no systemic complications were selected. They were randomly divided into three groups, i.e., Group I - CH group, Group II - TAP, and Group III - PB allocating 10 teeth in each group. After access opening, the first sample (S1) was collected by inserting a paper point into the root canal, the second sample (S2) was collected immediately after biomechanical preparation, and the third sample (S3) was collected after 7 days, i.e., postintracanal medication. Samples were sent for microbiological analysis to assess the microbial count, and statistical analysis was done for the obtained data.
RESULTS: The three intracanal medicaments were successful in reducing the microbial counts of Enterococcus faecalis in the infected root canals. However, according to the results of the
study, the PB group demonstrated greater effectiveness against E. faecalis compared to the CH group and displayed similar antimicrobial efficacy as the TAP group.
CONCLUSIONS: PB exhibited antimicrobial efficacy comparable to TAP but greater than Ca (OH) 2 paste. Hence, PB can be utilized as an intracanal medicament in young permanent teeth.